North America Proteomics Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The North America Proteomics Market Report is Segmented by Component (Instruments and More), Technology (Mass Spectrometry and More), Application (Drug Discovery & Development and More), End-User (Pharmaceutical & Biotechnology Companies and More), and Geography (United States, Canada, and Mexico). The Market Forecasts are Provided in Terms of Value (USD).

North America Proteomics Market Size and Share

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North America Proteomics Market Analysis by Mordor Intelligence

The North America proteomics market size stands at USD 13.26 billion in 2025 and is forecast to reach USD 22.76 billion by 2030, registering an 11.41% CAGR. Rising integration of artificial intelligence with modern mass-spectrometry platforms, steady consolidation among instrument suppliers, and expanding venture capital flows into multi-omics start-ups combined to keep the region ahead of global peers. Strategic deals, such as Thermo Fisher Scientific’s USD 3.1 billion purchase of Olink, show how incumbents lock in next-generation protein-analysis assets to shorten discovery timelines. United States-based pharmaceutical sponsors dominate early-stage demand for high-throughput workflows, while smaller biotechnology firms and academic users increasingly rely on contract research organizations to offset capital barriers. Fuel for long-run growth also comes from regulatory moves that give clinical laboratories clearer pathways to adopt proteomic diagnostics, pushing hospitals and reference labs to modernize their analytical fleets.

Key Report Takeaways

  • By component, reagents led with 63.41% of the North America proteomics market share in 2024; software & services is projected to expand at a 12.85% CAGR to 2030.
  • By technology, mass spectrometry accounted for 28.27% of the North America proteomics market size in 2024, whereas next-generation sequencing is set to accelerate at a 13.02% CAGR through 2030.
  • By application, drug discovery and development held 45.36% North America proteomics market share in 2024; precision and personalized medicine is advancing at a 13.46% CAGR to 2030.
  • By end-user, pharmaceutical and biotechnology companies captured 67.50% share in 2024, while contract research organizations record the fastest 12.31% CAGR through 2030.
  • By geography, the United States dominated with 77.89% market share in 2024; Mexico posts the highest 12.79% CAGR between 2025 and 2030.

Segment Analysis

By Component: Reagents Remain Cornerstone of Daily Workflows

Reagents captured 63.41% of the North America proteomics market share in 2024 because every experiment requires fresh antibodies, enzymes, buffers, and labeling kits. Suppliers lock in predictable revenue by bundling consumables with instruments. The software & services slice is much smaller, yet it delivers a 12.85% CAGR because laboratories must extract insights from high-volume data. Cloud platforms equipped with pretrained AI models simplify spectrum annotation, protein-protein interaction mapping, and clinical-trial report generation. Instruments command premium prices but represent a cyclical buy-decision. Vendors therefore tie service contracts to hardware to smooth cash flows and improve customer retention across the North America proteomics market.

Growth in software also reflects a pivot toward subscription models. Data analysis portals charge per sample or per month, turning unpredictable capital expenses into operating budgets. Managed-service firms now integrate LIMS, statistical pipelines, and regulatory-grade audit trails, letting understaffed hospitals gain modern capabilities without hiring full-time bioinformaticians. As data volumes swell, so does demand for encrypted cloud storage, backup, and cyber-security audits. Each of these trends adds momentum to the North America proteomics industry and lifts long-run platform value for developers who can enable seamless reagent-to-report workflows.

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By Technology: Mass Spectrometry Leads, Next-Generation Sequencing Climbs Quickly

Mass spectrometry held 28.27% of the North America proteomics market size in 2024, reflecting decades of reliability, vast legacy datasets, and broad regulatory acceptance. High-resolution Orbitrap and time-of-flight systems now pair with foundation AI models that predict spectrum quality and post-translational modifications in real time. Next-generation sequencing platforms chart a 13.02% CAGR because vendors blend genomics, transcriptomics, and proteomics into single multi-omics reads. Illumina plans to commercialize spatial transcriptomics add-ons by 2026, combining its sequencers with NVIDIA GPUs to accelerate protein-structure insight within oncology studies.

Microfluidic sample-handling tools shrink reaction volumes, enabling low-cost point-of-care tests for infectious-disease proteotyping. Chromatography and capillary electrophoresis retain niche relevance for sample cleanup, while protein microarrays support high-throughput antibody discovery. Hybrid instruments that combine MS, NGS, and fluorescence-imaging modules reduce laboratory footprints and maximize asset utilization. Such convergence improves workflow efficiency, keeping end users loyal to suppliers that provide total solutions, thereby expanding the North America proteomics market.

By Application: Drug Discovery Dominant but Precision Medicine Accelerates

Drug discovery and development consumed 45.36% of the North America proteomics market size in 2024 because pharmaceutical sponsors rely on protein-level readouts from target validation through toxicity assessment. Companion-diagnostic development for antibody-drug conjugates keeps MS core facilities booked months in advance. Precision and personalized medicine, however, grows at 13.46% CAGR as hospitals deploy proteomic assays to stratify patients and monitor therapy in near real time. The FDA introduced a distinct classification for clinical mass-spectrometry devices in 2024, opening a clearer regulatory path for lab-developed proteomic tests.

Biomarker discovery remains critical because plasma proteomics panels now quantify more than 9,000 proteins per patient, enriching longitudinal cohorts for cardiovascular and neurodegenerative research. Agricultural and environmental proteomics emerge as spill-over segments, especially for food-safety surveillance. Vendors that package discovery, clinical trial support, and companion diagnostics in one offering win larger contracts, increasing competitive intensity within the North America proteomics market.

Proteomics Market: Market Share by Application
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Note: Segment shares of all individual segments available upon report purchase

By End-User: Contract Research Organizations Gain Momentum

Pharmaceutical and biotechnology companies still represented 67.50% revenue share in 2024 because they fund in-house target discovery and IND-enabling studies. Yet CROs log a 12.31% CAGR because sponsors convert fixed costs into variable fees by outsourcing proteomic workflows. The U.S. CMO/CRO industry is projected to grow at a fast pace by 2033. CROs, therefore, build specialized mass-spectrometry fleets and recruit data-science talent to provide end-to-end services.

Academic and government institutes remain vital for method innovation, yet grant budgets limit equipment refresh cycles. Diagnostic laboratories enter the market as new regulatory clarity encourages them to validate MS-based assays for metabolic disorders. Equipment vendors respond by launching benchtop sequencers such as Quantum-Si’s Platinum Pro, designed for small-volume clinical settings. These dynamics diversify revenue streams and broaden the North America proteomics market base.

Geography Analysis

United States facilities underpin 77.89% of the North America proteomics market size in 2024 because they host the largest concentration of pharmaceutical R&D budgets, clinical trial centers, and core mass-spectrometry laboratories. Regulatory frameworks shape demand: the FDA’s updated rules for laboratory-developed tests and clinical mass-spectrometry systems tightened compliance obligations yet also standardized expectations, enabling faster rollout of nationwide testing programs. Strategic acquisitions such as Thermo Fisher’s Olink deal and Agilent’s BIOVECTRA purchase reinforce U.S. leadership by embedding cutting-edge immuno-proteomics platforms into local supply chains. Venture investment cycles stay robust, with multiple proteomics start-ups exceeding USD 1 billion valuations within three years of launch, although hiring constraints in bioinformatics continue to slow project delivery. The country’s forecast CAGR through 2030 is 11.02%, confirming its anchor role in the North America proteomics market.

Canada accelerates at 11.96% CAGR thanks to public programs that train the next generation of biomanufacturing and analytical specialists. The federal workforce study highlighted demand for 65,000 new life-science employees by 2029. Harmonized regulatory frameworks let Canadian research institutes participate in cross-border oncology trials, drawing instrument placements northward. Favorable exchange rates and provincial tax incentives attract foreign sponsors looking for cost-efficient collaborative sites. However, shortages of senior computational biologists limit the pace at which local CROs can seize large-scale multi-omics contracts. Addressing these gaps will determine how much extra share Canada secures within the North America proteomics market.

Mexico records the fastest 12.79% CAGR because nearshoring policies coax multinational drug manufacturers to expand production campuses in Guadalajara and Monterrey. Government incentives for clinical-research infrastructure and alignment with FDA quality guidelines lower operational risk for sponsors, thereby boosting orders for proteomic instrumentation across central reference labs. Domestic talent pipelines still lack advanced bioinformatics training, so global companies partner with universities to develop certificate programs in mass-spectrometry data analysis. Infrastructure upgrades remain the main bottleneck, yet steady capital inflows from multinational clients position Mexico as the rising star of the North America proteomics market.

Competitive Landscape

Competition centers on end-to-end solutions that merge high-resolution detection with cloud-native analytics. Market leaders pursue bolt-on deals: Thermo Fisher added Olink’s proximity-extension assay to strengthen single-cell and low-abundance protein coverage, while Agilent folded BIOVECTRA into its portfolio to secure GMP biologics production capacity. Illumina’s alliance with NVIDIA embeds accelerated DRAGEN pipelines into sequencers, giving users real-time multi-omics alignment. Such moves signal that hardware margins alone no longer suffice; companies must own data infrastructure and analytical IP to defend share in the North America proteomics market.

Emerging disruptors target field-deployable workflows. Portable microfluidic prep kits pair with acoustic-ejection MS to enable same-day biomarker panels in oncology clinics. Start-ups also use large protein-protein interaction datasets to train foundation models that infer druggable sites with minimal lab work. Intellectual-property strategy shifts alongside technology: recent USPTO guidance on means-plus-function claims for antibodies broadens patent scope, letting innovators protect epitope-agnostic functionalities. This raises entry barriers yet invites litigation that could reshape control points within the North America proteomics industry.

Competitive intensity rises as CROs spin up full-service proteomics divisions. Vendors now bundle hardware leases, reagent consumables, data-science support, and regulatory documentation into multiyear contracts. Price competition focuses less on per-run costs and more on total turnaround time to clinical decision. Customers gravitate toward partners that can deliver validated data, integrate laboratory information-management systems, and withstand cybersecurity audits. Players that fail to scale AI pipelines or secure niche assay IP risk margin compression and share erosion in the North America proteomics market.

North America Proteomics Industry Leaders

  1. Agilent Technologies, Inc

  2. Bruker Corporation

  3. Danaher Corporation

  4. Illumina Inc.

  5. Thermo Fisher Scientific Inc.

  6. *Disclaimer: Major Players sorted in no particular order
North America Proteomics Market Concentration
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Recent Industry Developments

  • June 2025: Thermo Fisher Scientific unveiled Orbitrap Astral Zoom and Orbitrap Excedion Pro instruments, offering enhanced speed and sensitivity aimed at precision oncology workflows.
  • June 2025: Waters Corporation introduced BioResolve Protein A Affinity Columns using MaxPeak Premier Technology to raise antibody titer sensitivity sevenfold for biotherapeutic development.
  • January 2025: Quantum-Si launched Platinum Pro benchtop protein sequencer featuring Pro Mode for custom application development, with Avantor as exclusive distributor in the United States and Canada.
  • January 2025: Illumina announced collaboration with NVIDIA to accelerate multi-omic data analysis by integrating DRAGEN pipelines with GPU architecture.

Table of Contents for North America Proteomics Industry Report

1. Introduction

  • 1.1 Study Assumptions & Market Definition
  • 1.2 Scope of the Study

2. Research Methodology

3. Executive Summary

4. Market Landscape

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Escalating adoption of personalized medicine
    • 4.2.2 Surge in proteomics?specific funding
    • 4.2.3 Breakthroughs in high-throughput MS platforms
    • 4.2.4 Expansion of biopharma proteomics spending
    • 4.2.5 AI-enabled proteogenomic decision tools
    • 4.2.6 Field-deployable microfluidic sample-prep kits
  • 4.3 Market Restraints
    • 4.3.1 High capital cost of instruments
    • 4.3.2 Bioinformatics talent shortage
    • 4.3.3 Patent thickets on affinity reagents
    • 4.3.4 Cyber-security risks in cloud multi-omics
  • 4.4 Supply Chain Analysis
  • 4.5 Regulatory Landscape
  • 4.6 Technological Outlook
  • 4.7 Porter's Five Forces Analysis
    • 4.7.1 Threat of New Entrants
    • 4.7.2 Bargaining Power of Buyers
    • 4.7.3 Bargaining Power of Suppliers
    • 4.7.4 Threat of Substitutes
    • 4.7.5 Intensity of Competitive Rivalry

5. Market Size & Growth Forecasts (Value)

  • 5.1 By Component
    • 5.1.1 Instruments
    • 5.1.2 Reagents
    • 5.1.3 Software and Services
  • 5.2 By Technology
    • 5.2.1 Mass Spectrometry
    • 5.2.2 Spectroscopy
    • 5.2.3 Chromatography
    • 5.2.4 Next-Generation Sequencing
    • 5.2.5 Protein Microarrays
    • 5.2.6 Microfluidics
    • 5.2.7 X-ray Crystallography
    • 5.2.8 Other Technologies
  • 5.3 By Application
    • 5.3.1 Drug Discovery & Development
    • 5.3.2 Clinical Diagnostics
    • 5.3.3 Biomarker Discovery
    • 5.3.4 Precision and Personalized Medicine
    • 5.3.5 Agricultural & Environmental Proteomics
    • 5.3.6 Other Applications
  • 5.4 By End-user
    • 5.4.1 Pharmaceutical & Biotechnology Companies
    • 5.4.2 Academic & Research Institutes
    • 5.4.3 Contract Research Organizations
    • 5.4.4 Other End-users
  • 5.5 By Geography
    • 5.5.1 United States
    • 5.5.2 Canada
    • 5.5.3 Mexico

6. Competitive Landscape

  • 6.1 Market Concentration
  • 6.2 Competitive Benchmarking
  • 6.3 Market Share Analysis
  • 6.4 Company Profiles (includes Global level Overview, Market level overview, Core Segments, Financials as available, Strategic Information, Market Rank/Share for key companies, Products & Services, and Recent Developments)
    • 6.4.1 Agilent Technologies Inc.
    • 6.4.2 Alamar Biosciences, Inc.
    • 6.4.3 Bioinformatics Solutions Inc.
    • 6.4.4 Bio-Rad Laboratories Inc.
    • 6.4.5 Bruker Corporation
    • 6.4.6 Creative Proteomics
    • 6.4.7 Danaher Corporation
    • 6.4.8 GE Healthcare
    • 6.4.9 Illumina Inc.
    • 6.4.10 Merck KGaA
    • 6.4.11 Nautilus Biotechnology
    • 6.4.12 Oxford Nanopore Technologies
    • 6.4.13 Promega Corporation
    • 6.4.14 QIAGEN N.V.
    • 6.4.15 Revvity, Inc.
    • 6.4.16 Seer Inc.
    • 6.4.17 Shimadzu Corporation
    • 6.4.18 SomaLogic Inc.
    • 6.4.19 Thermo Fisher Scientific Inc.
    • 6.4.20 Waters Corporation

7. Market Opportunities & Future Outlook

  • 7.1 White-space & Unmet-Need Assessmen
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North America Proteomics Market Report Scope

As per the scope of the report, proteomics is the large-scale study of proteomes. A proteome is a set of proteins produced in an organism, system, or biological context. The North American proteomics market is segmented by type (instrumentation technology (spectroscopy, chromatography, electrophoresis, protein microarrays, X-Ray crystallography, and other instrumentation technologies), services and software (core proteomics services and bioinformatics software and services), and reagents), application (clinical diagnostics, drug discovery, and other applications), and geography (United States, Canada, and Mexico). The report offers values in USD million for all the above-mentioned segments.

By Component Instruments
Reagents
Software and Services
By Technology Mass Spectrometry
Spectroscopy
Chromatography
Next-Generation Sequencing
Protein Microarrays
Microfluidics
X-ray Crystallography
Other Technologies
By Application Drug Discovery & Development
Clinical Diagnostics
Biomarker Discovery
Precision and Personalized Medicine
Agricultural & Environmental Proteomics
Other Applications
By End-user Pharmaceutical & Biotechnology Companies
Academic & Research Institutes
Contract Research Organizations
Other End-users
By Geography United States
Canada
Mexico
By Component
Instruments
Reagents
Software and Services
By Technology
Mass Spectrometry
Spectroscopy
Chromatography
Next-Generation Sequencing
Protein Microarrays
Microfluidics
X-ray Crystallography
Other Technologies
By Application
Drug Discovery & Development
Clinical Diagnostics
Biomarker Discovery
Precision and Personalized Medicine
Agricultural & Environmental Proteomics
Other Applications
By End-user
Pharmaceutical & Biotechnology Companies
Academic & Research Institutes
Contract Research Organizations
Other End-users
By Geography
United States
Canada
Mexico
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Key Questions Answered in the Report

What makes reagents a cornerstone revenue stream in North American proteomics workflows?

Every experiment depends on a fresh supply of antibodies, enzymes, and labeling kits, creating steady, repeat-purchase demand that cushions suppliers against swings in capital-equipment budgets.

How is artificial intelligence (AI) changing proteomics workflows in pharmaceutical R&D?

AI models now annotate spectra in real time and predict post-translational modifications, allowing researchers to move from raw data to biological insight in hours instead of days.

Why are contract research organizations becoming indispensable partners for biotech firms?

CROs let sponsors convert fixed lab costs into flexible service fees while offering access to specialized mass-spectrometry fleets and experienced data-science teams that many small companies cannot staff in-house.

What recent regulatory developments are influencing adoption of clinical proteomic diagnostics in the United States?

The FDA’s creation of a dedicated classification for mass-spectrometry devices gives clinical laboratories clearer compliance paths, encouraging hospitals to add protein-based assays to their test menus.

Which technological innovations are most effective at shortening drug-discovery timelines in proteomics?

High-throughput Orbitrap instruments paired with acoustic-ejection sample loaders can process thousands of peptides per day, enabling faster target validation and biomarker screening.

How does the bioinformatics talent gap affect instrument utilization and project delivery?

Limited availability of specialists who can build and maintain multi-omics pipelines often leaves expensive instruments idle and forces companies to outsource data analysis, extending experimental lead times.

Page last updated on: June 24, 2025

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