Digestive Enzymes Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The Digestive Enzymes Market is segmented by Enzyme Type (Carbohydrase, Protease, Lipase, and Other Enzyme Types), Origin (Animal, Microbial, and Plant), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Digestive Enzymes Market Size

Digestive Enzymes Market Summary
Study Period 2019 - 2029
Base Year For Estimation 2023
CAGR 8.30 %
Fastest Growing Market Asia Pacific
Largest Market North America
Market Concentration Low

Major Players

Digestive Enzymes Market Major Players

*Disclaimer: Major Players sorted in no particular order


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Digestive Enzymes Market Analysis

The digestive enzymes market is expected to register a CAGR of 8.3% over the forecast period-2022-2027.  

The novel coronavirus has significantly impacted all industries, including food and beverage, automotive, chemicals, and many others. This pandemic has resulted in mass production shutdowns and supply chain disruptions, which have affected the global economy. Thus, such factors adversely affected the market initially. However, increasing gastrointestinal symptoms among patients who have suffered from COVID-19 positively impacted the market in later times. According to the study titled, "Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome" published in December 2020, COVID-19 patients experienced gastrointestinal symptoms such as anorexia (17.9%), nausea (17.9%), and diarrhea (24.2%). It also reported that in patients who suffered severely from COVID-19, the symptoms of gastrointestinal disorders became more pronounced. Digestive enzymes help to break food substances for easy digestion. These proteins speed up chemical reactions that turn nutrients into substances so that the digestive tract can absorb. Thus, digestive enzymes are one of the essential element for treating gastrointestinal disorders. Therefore, such instances indicate that the market witnessed a positive impact during later times of the pandemic.

Factors such as the rising geriatric population, the rising prevalence of gastrointestinal disorders, increasing awareness about GI health, and focus on preventive health management are contributing to the market growth. The global population is aging rapidly, owing to reduced birth rates and rising life expectancy. The demographic trend toward an elderly population represents a rising need for the management of disorders, such as GI tract obstructions. According to the report published by the World Health Organisation in October 2021, the proportion of the population aged 60 and over will increase from 1 billion in 2020 to 1.4 billion in 2030. It also reported that by 2050, the world's population of people aged 60 and over will double around 2.1 billion. The secretion of digestive enzymes usually reduces with age that contributes to high levels of gastric discomfort, lower digestion rates, reduced food consumption, and/or a variety of other GI disorders. Therefore, with the rising elderly population, the market for digestive enzymes is expected to grow over the forecast period.

However, perception of probiotic and prebiotic products as alternatives to digestive enzymes and stringent regulatory policies are likely to hinder the market growth over the forecast period.

Digestive Enzymes Market Trends

This section covers the major market trends shaping the Digestive Enzymes Market according to our research experts:

Animal Origin Enzymes Segment is Expected to Witness Growth Over the Forecast Period

The animal-origin digestive enzyme segment holds a significant market share in the origin segment and is expected to continue the same trend over the forecast period. The animal origin digestive enzymes are usually extracted from the pancreas of the swine, calf, or hogs. Pancreatin, Trypsin, Chymotrypsin, and Trypsin-Chymotrypsin mixture are some of the common animal-derived digestive enzymes. Pancreatin is a digestive enzyme produced by the pancreas and delivered to the small intestine for the hydrolysis of complex nutrients. Trypsin is a proteolytic enzyme crystallized from an extract of the pancreas gland of the ox. Chymotrypsin is a proteolytic enzyme crystallized from an extract of the pancreas gland of the ox. Trypsin-Chymotrypsin Mixture is a blend containing trypsin and chymotrypsin in different rations

Increasing cases of gastrointestinal disorders across the globe is one of the major drivers contributing to the segment growth. For instance, as per the study titled, "Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study" published in January 2021, more than 40.0% of persons globally have functional gastrointestinal disorders which affect quality of life and health care use. The animal derived digestive enzymes are considered as one of the effective treatments for such conditions therefore, increasing cases of gastrointestinal disorders is anticipated to positively impact the segment growth. Furthermore, many key players are involved in various growth strategies, such as collaborations, partnerships, agreements, and mergers and acquisitions that are expected to drive the market. In May 2020, Nestlé Health Science (NHSc) announced the successful completion of the asset purchase of Zenpep and Viokace, expanding NHSc's portfolio. ZENPEP and VIOKACE, available in the United States, are a combination of porcine-derived lipases, proteases, and amylases indicated for the treatment of exocrine pancreatic insufficiency. Thus, owing to the aforementioned factors, the animal origin segment is expected to witness significant growth over the forecast period.

Digestive Enzymes Market - Elderly Population (in million) in the United States, 2021 and 2050

North America is Expected to Dominate the Digestive Enzymes Market Over the Forecast Period

North America is expected to dominate the overall digestive enzymes market, over the forecast period. The growth is due to factors such as the rising cases of gastrointestinal disorders and the increasing geriatric population. For instance, according to the report published by the United Health Foundation in April 2021, more than 54.0 million adults ages 65 and older live in the United States in 2021 which is accounting for about 16.5% of the nation's population. The geriatric population is prone to gastrointestinal disorders owing to which positively impacts the market. For instance, according to the study titled, "Common Gastroenterology Disorders in the Elderly" published in February 2021, elderly patients experience increased rates of esophageal and gastric disorders, with a higher incidence of motility abnormalities, gastroesophageal reflux, reflux complications, gastric ulcers, and GI bleeding. Therefore, such instances are anticipated to propel market growth in this region.

Key product launches, increasing research work, high concentration of market players or manufacturer's presence, and acquisition & partnerships among major players in the United States are some of the factors driving the growth of the digestive enzyme market in the country. For instance, In March 2020, Klaire Labs launched Ther-biotic Synbiotic, the next-evolution, shelf-stable combination of prebiotic and probiotics strains, in the United States. Such instances are anticipated to drive the growth of the market in the country.

Therefore, owing to the aforesaid factors the growth of the studied market is anticipated in the North America Region.

Digestive Enzyme Market - Growth Rate by Region

Digestive Enzymes Industry Overview

The digestive enzymes market is fragmented in nature due to the presence of several companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international as well as local companies which hold the market shares and are well known including Zeus Biotech Limited, Klaire Labs, Amway Corporation, AbbVie Inc., and Biotics Research Corporation among others.

Digestive Enzymes Market Leaders

  1. AbbVie Inc.

  2. Biotics Research Corporation

  3. Klaire Labs

  4. Amway Corporation

  5. Zeus Biotech Pvt. Ltd.

*Disclaimer: Major Players sorted in no particular order

Digestive Enzymes Market Concentration
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Digestive Enzymes Market News

  • In February 2022, Bio-Cat Inc is sponsoring a clinical trial at the University Illinois at Urbana-Champaign to investigate the efficacy of a digestive enzyme blend that aims to improve protein digestion and gastrointestinal tolerance
  • In February 2022, Mimi's Rock Corp. announced that its supplements brand, Dr. Tobias, is expanding its product portfolio with digestive enzymes with prebiotics and probiotics to support gut health developed to meet growing market demand in the digestive health space

Digestive Enzymes Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Rising Geriatric Population

      2. 4.2.2 Rising Prevalence of Gastrointestinal Disorders

      3. 4.2.3 Increasing Awareness about GI Health and Focus on Preventive Health Management

    3. 4.3 Market Restraints

      1. 4.3.1 Perception of Probiotic and Prebiotic Products as Alternatives to Digestive Enzymes

      2. 4.3.2 Stringent Regulatory Policies

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD Million)

    1. 5.1 By Enzyme Type

      1. 5.1.1 Carbohydrase

      2. 5.1.2 Protease

      3. 5.1.3 Lipase

      4. 5.1.4 Other Enzyme Types

    2. 5.2 By Origin

      1. 5.2.1 Animal

      2. 5.2.2 Microbial

      3. 5.2.3 Plant

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 AbbVie Inc.

      2. 6.1.2 Amway Corporation

      3. 6.1.3 AST Enzyme

      4. 6.1.4 Biotics Research Corporation

      5. 6.1.5 Country Life LLC

      6. 6.1.6 Enzymedica

      7. 6.1.7 Enzymes Inc.

      8. 6.1.8 Garden of Life Inc.

      9. 6.1.9 Integrative Therapeutics

      10. 6.1.10 Klaire Labs

      11. 6.1.11 Metagenics

      12. 6.1.12 National Enzyme Company

      13. 6.1.13 Nestle SA

      14. 6.1.14 ProteoZymes

      15. 6.1.15 Zeus Biotech Pvt. Ltd.

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Digestive Enzymes Industry Segmentation

As per the scope of the report, digestive enzymes represent a group of enzymes secreted by the digestive organs to break down complex macromolecules into their constituents to facilitate their absorption by the body. Several digestive enzymes are commercially available as dietary supplements for the management of digestive disorders. The digestive enzymes market is segmented by enzyme type (Carbohydrase, Protease, Lipase, and Other Enzyme Types), origin (Animal, Microbial, and Plant), and geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.

By Enzyme Type
Other Enzyme Types
By Origin
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America
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Digestive Enzymes Market Research FAQs

The Global Digestive Enzymes Market is projected to register a CAGR of 8.30% during the forecast period (2024-2029)

AbbVie Inc., Biotics Research Corporation, Klaire Labs, Amway Corporation and Zeus Biotech Pvt. Ltd. are the major companies operating in the Global Digestive Enzymes Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Global Digestive Enzymes Market.

The report covers the Global Digestive Enzymes Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Global Digestive Enzymes Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Global Digestive Enzymes Industry Report

Statistics for the 2024 Global Digestive Enzymes market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Digestive Enzymes analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Digestive Enzymes Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)