Cold Plasma in Healthcare Market - Growth, Trends, COVID-19 Impact, and Forecasts (2023 - 2028)

The Cold Plasma in Healthcare Market is segmented by Application (Wound Healing, Surgical Application and Other Medical Applications), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report offers the value (in USD million) for the above segments.

Healthcare Cold Plasma Industry Overview

Market Snapshot
Study Period: 2018 - 2028
Fastest Growing Market: Europe
Largest Market: North America
CAGR: 15.3 %

Major Players


*Disclaimer: Major Players sorted in no particular order


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Healthcare Cold Plasma Market Analysis

The cold plasma in the healthcare market is expected to grow with a CAGR of 15.3% during the forecast period.

The COVID-19 pandemic has impacted the cold plasma market due to disruptions to various treatments and supply chains. The disruption in the supply chain during COVID-19 and the delay in the delivery of essential products required for the manufacturing of cold plasma had an adverse effect on the market. Some major issues faced by the market during a pandemic include trucking bottlenecks and port checkpoints slowing down their deliveries, including critical supplies; export bans imposed in many countries, only a few manufacturing units were functional, lack of healthcare workers to transport and produce products; lack of proper coordination and alignment among federal, local, and state agencies as well as among healthcare organizations, which lead to a fragmented approach towards ordering and fulfillment. However, with restored services, treatment procedures, increased hospital visits, and decreasing restrictions on COVID-19, the demand for cold plasma in the treatment of various diseases and infections is likely to increase, which is expected to boost market growth over the forecast period.

Factors driving the growth of the market are environmental friendliness and other benefits of cold plasma techniques and the increasing use of cold plasma in wound healing. In addition, the use of cold plasma in dentistry is increasing due to the advantages of cold plasma over other methods. For example, according to an article published by Materials Today Bio in January 2022 entitled "Aurora Borealis in Dentistry: Cold Plasma Applications in Biomedicine", cold plasma was observed to decontaminate dental caries without the need for drilling, as compared to mechanical methods that are used to clean an infected tooth, and its active plasma particles can penetrate deep into the cavity.

Cold plasma is effectively combined with chemotherapy in the treatment of cancer and promotes wound sterilization, blood coagulation, and cell proliferation in wound healing. Its use enables effective medical treatment of cancer and various skin injuries and diseases. For example, according to an article published in the journal Oxidative Medicine and Cellular Longevity in December 2021 titled "Cold Physical Plasma in Cancer Therapy: Mechanism, Signalling, and Immunity", treatment of tumor tissue in the head and neck with cold argon plasma led to higher levels of extracellular cytochrome c and triggered more apoptotic cells than in healthy tissue. Cold argon plasma can also selectively kill cancer cells more effectively than non-neoplastic cells. Thus, cold argon plasma is effective in killing cancer cells without any side effects, which is expected to increase the demand for cold plasma treatment, thereby fueling market growth.

However, the lack of awareness about cold plasma technology in the healthcare industry and stringent regulatory policies are likely to restrain the growth of the market.

Healthcare Cold Plasma Industry Segments

As per the scope of the report, cold plasma is an ionized gas at room temperature that is created by electric discharge. The cold plasma treatment is a contact-free and painless procedure to sterilize wounds and promote wound healing. The costs are comparable to or lower than those of standard antimicrobial wound treatment. The Cold Plasma in Healthcare Market is segmented by Application (Wound Healing, Surgical Application, and Other Medical Applications), and Geography (North America, Europe, Asia-Pacific, and South America). The report offers the value (in USD million) for the above segments.

By Application
Wound Healing
Surgical Application
Other Medical Applications
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Rest of World

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Healthcare Cold Plasma Market Trends

This section covers the major market trends shaping the Healthcare Cold Plasma Market according to our research experts:

Wound Healing Segment is Expected to Hold a Significant Market Share

The wound healing segment is expected to hold a significant market share as cold plasma can kill bacteria, including drug-resistant bacteria, to prevent further infection rates, promote the wound healing process, and eliminate further complications. For instance, according to an article published by Semantic in June 2020, titled "Cold atmospheric plasma as an effective method to treat diabetic foot ulcer: A randomized clinical trial", it has been observed that cold atmospheric plasma applied to a patient's wound three times a week for three consecutive weeks have shown a reduction in the wound size. Cold plasma decreases the bacterial load in chronic wounds and promotes healing without any significant side effects on normal tissue. Additionally, it has been observed that helium cold atmospheric plasma (CAP) therapy lowers the pH of the aqueous medium, which may cause wound acidification and thus speeds up the healing process.

In addition, according to the World Health Organization 2020, there are more than 1.35 million people that die every year as a result of road traffic crashes and accidents. Road traffic injuries are the leading cause of death among people aged between 15 and 29 years. Every year, the lives of more than 1.4 million people are cut short as a result of road traffic crashes. Therefore, since there are a large number of trauma and wound management cases observed yearly, the adoption rate of cold plasma is expected to increase for wound healing across hospitals and healthcare facilities.

Moreover, as the geriatric population is increasing, they are more prone to developing chronic wounds due to various conditions such as diabetes and peripheral artery disease. For instance, according to the World Population Ageing Highlight 2020 report published by the United Nations, the global geriatric population is increasing rapidly around the world, and in 2020, about 727.0 million people of age 65 years or more were living across the world, which was about 9.3% of the total global population. Also, the same report projected that the population of people of age 65 years or more will be about 1.5 billion people by 2050, which will be about 16.0% of the global population. Thus, the growing aging population will have a significant impact on the growth of the studied segment over the next few years and is expected to drive the growth of the cold plasma market.

Thus, the rising geriatric population, increasing incidences of road accidents, and the increasing usage of cold plasma for the treatment of chronic wounds are anticipated to increase the demand for the studied segment, thereby boosting the segment’s growth.

Estimated Aging Population aged 65 years or over (thousands), 2019-2050, Global

North America is Expected to Register Higher Growth Over the Forecast Period

The North American region is expected to register a high CAGR in the cold plasma market owing to the increasing prevalence of chronic diseases such as cancer and diabetes, the presence of key industry players, and the adoption of cold plasma technology in healthcare.

The rising burden of cancer is likely to increase the demand for cold plasma therapy with minimal side effects. For instance, according to the statistics published by the Canadian Cancer Society in 2021, around 4,000 Canadians were diagnosed with stomach cancer and 1,950 deaths occurred in Canada by the end of 2021. In addition, as per the American Society of Clinical Oncology 2021 report, an estimated 235,760 adults (119,100 men and 116,6600 women) in the United States were diagnosed with lung cancer. Similarly, according to statistics published by the American Association of Cancer Research, in 2021 approximately 26,560 new cases of stomach cancer were detected in the United States, with 16,160 males and 10,400 women. Cold plasma treatment is considered one of the most effective cancer treatments as it helps to eliminate cancerous cells and promotes the healing of cancerous lesions. Thus, the increasing prevalence of cancer is expected to increase the demand for cold plasma therapy, thereby boosting market growth.

In addition, the rising number of dental caries cases among the population, especially in children and the geriatric population, is likely to increase the demand for non-drilling and effective treatment as well as maintain patient comfort, which increases the demand for cold plasma therapy, in turn fueling the market's growth.

Moreover, the increasing company focus on utilizing cold atmospheric plasma technology for treating various chronic diseases and conditions is anticipated to increase the growth of the cold plasma market over the forecast period. For instance, in September 2021, United States Medical Innovations presented the positive results of Phase I clinical trial using cold atmospheric plasma for the treatment of solid tumors at the Baird Global Healthcare Conference.

Thus, the rising prevalence of cancer, the growing geriatric population, and increasing company activities are anticipated to drive the market's growth over the forecast period.

Cold Plasma in Healthcare Market2

Healthcare Cold Plasma Market Competitor Analysis

The cold plasma in the healthcare market is consolidated and competitive. The competitive landscape includes an analysis of a few international as well as local companies which hold the market shares and are well known, including ADTEC Plasma Technology Co., Ltd., CINOGY System GmBH, U.S. Medical Innovation, Neoplas med GmBH, Apyx Medical, and Terraplasma Medical GmbH, among others.

Healthcare Cold Plasma Market Top Players

  1. Neoplas med GmbH

  2. U.S. Medical Innovations

  3. terraplasma medical GmbH

  4. Adtec Healthcare

  5. Apyx Medical

*Disclaimer: Major Players sorted in no particular order


Healthcare Cold Plasma Market Recent Developments

  • In March 2022, Neoplas Med GmbH announced the superiority of cold atmospheric plasma beam therapy in the treatment of chronic wounds with a gold standard trial. A comparative clinical study demonstrated significant improvement in wound closure and infection control following treatment with plasmajet kINPen MED from Neoplas Med compared to other wound care procedures.
  • In September 2021, US Medical Innovations, LLC (USMI), an FDA-registered United States life sciences and biomedical device company, and the Jerome Canady Research Institute for Advanced and Biological Technological Sciences (JCRI-ABTS), announced the successful results of Phase I clinical trial using cold atmospheric plasma for the treatment of solid tumors at the Baird 2021 Global Healthcare Conference.

Healthcare Cold Plasma Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Defination

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Environment Friendliness and Other Benefits of Cold Plasma Techniques

      2. 4.2.2 Increasing Use of Cold Plasma in Wound Healing

    3. 4.3 Market Restraints

      1. 4.3.1 Lack of Awareness about Cold Plasma Technology in the Healthcare Industry and Stringent regulatory Policies

    4. 4.4 Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Application

      1. 5.1.1 Wound Healing

      2. 5.1.2 Surgical Application

      3. 5.1.3 Other Medical Applications

    2. 5.2 Geography

      1. 5.2.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.2.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.2.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.2.4 Rest of World


    1. 6.1 Company Profiles

      1. 6.1.1 ADTEC Plasma Technology Co. Ltd

      2. 6.1.2 Neoplas med GmbH

      3. 6.1.3 U.S. Medical Innovations

      4. 6.1.4 CINOGY System GmbH

      5. 6.1.5 terraplasma medical GmbH

      6. 6.1.6 Apyx Medical

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments
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Healthcare Cold Plasma Market Research FAQs

The Global Cold Plasma in Healthcare Market is studied from 2018 - 2028.

The Global Cold Plasma in Healthcare Market is growing at a CAGR of 15.3% over the next 5 years.

Europe is growing at the highest CAGR over 2018 - 2028.

North America holds highest share in 2021.

Neoplas med GmbH, U.S. Medical Innovations, terraplasma medical GmbH, Adtec Healthcare, Apyx Medical are the major companies operating in Global Cold Plasma in Healthcare Market.

Global Cold Plasma in Healthcare Industry Reports

In-depth industry statistics and market share insights of the Global Cold Plasma in Healthcare sector for 2020, 2021, and 2022. The Global Cold Plasma in Healthcare research report provides a comprehensive outlook of the market size and an industry growth forecast for 2023 to 2028. Available to download is a free sample file of the Global Cold Plasma in Healthcare report PDF.

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