United States Esoteric Testing Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Report Includes United States Esoteric Testing Market Growth Trends and is segmented by Type (Infectious Diseases Testing, Endocrinology Testing, Oncology Testing, Genetic Testing, Toxicology Testing, Immunology Testing, Neurology Testing, and Others) and Technology (Chemiluminescence Immunoassay, Enzyme-Linked Immunosorbent Assay, Mass Spectrometry, Real-Time PCR, Flow Cytometry, Radioimmunoassay, and Other Technologies). The Market Size and Forecast are Provided in Terms of Value (In USD Million) for the Above Segments.

United States Esoteric Testing Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

United States Esoteric Testing Market Size

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United States Esoteric Testing Market Summary
Study Period 2019 - 2030
Base Year For Estimation 2024
Forecast Data Period 2025 - 2030
Market Size (2025) USD 9.10 Billion
Market Size (2030) USD 12.59 Billion
CAGR (2025 - 2030) 6.70 %
Market Concentration Medium

Major Players

United States Esoteric Testing Market Major Players

*Disclaimer: Major Players sorted in no particular order

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United States Esoteric Testing Market Analysis

The United States Esoteric Testing Market size is estimated at USD 9.10 billion in 2025, and is expected to reach USD 12.59 billion by 2030, at a CAGR of 6.7% during the forecast period (2025-2030).

The COVID-19 epidemic had an impact on the growth of the esoteric testing market in the United States. The COVID-19 pandemic has put a strain on the US healthcare system and boosted the need for ELISA and RT-PCR testing to detect COVID-19. For instance, in February 2021, Agilent Technologies Inc. launched the Agilent Dako SARS-CoV-2 IgG Enzyme-Linked Immunosorbent Assay (ELISA) kit to detect immunoglobulin G (IgG) antibodies qualitatively to SARS-CoV-2 in human serum or plasma. Thus, the demand for esoteric testing has increased during the pandemic. However, the market continued to grow post-pandemic over the forecast period due to the significant adoption of esoteric testing in the diagnosis of chronic and infectious diseases.

The rise in the prevalence of chronic and infectious diseases in the United States, advancements in R&D activities in the healthcare sector, increased population awareness for early diagnosis, and an increase in the number of diagnostic tests are expected to significantly contribute to the growth of the United States esoteric testing market during the forecast period. For instance, as stated in the American Heart Association 2021 Journal, it is estimated that by the year 2035, more than 130 million adults in the United States will have some type of heart disease. Additionally, according to Cancer Facts and Figures 2022, published in January 2022 by the American Cancer Society, there were around 1.9 million new cancer diagnoses and 609,360 cancer-related deaths in the United States in 2022. The need for precise diagnosis and treatment is enhanced by the rising incidence of cancer and the significant burden of other chronic diseases. This is likely to boost the adoption of esoteric testing for early diagnosis purposes, which will ultimately spur market expansion over the forecast period.

Moreover, market participants are concentrating on the development of innovative techniques for utilizing esoteric testing technology. For instance, in June 2021, Thermo Fisher Scientific introduced the Invitrogen Attune CytPix flow cytometer, which allows users to better comprehend cell morphology and quality. Thus, all the aforementioned factors are expected to boost market growth over the forecast period. However, the high price of diagnostic procedures has limited the growth of the market.

United States Esoteric Testing Industry Overview

The United States' esoteric testing market is consolidated with the presence of several players. It encourages innovation, research, and development. Companies like Labcorp, Quest Diagnostics, OPKO Health Inc., Laboratory Corporation of America, Fulgent Genetics, Mayo Medical Laboratories, Invitae, Myriad Genetics, Nordic Laboratories, Genomic Health, American Esoteric Laboratories (AEL), Miraca Holdings hold a substantial market share in the Esoteric Testing market.

United States Esoteric Testing Market Leaders

  1. Laboratory Corporation of America Holding

  2. Opko Health Company

  3. Mayo Medical Laboratories

  4. Invitae

  5. Myriad Genetics

  6. *Disclaimer: Major Players sorted in no particular order
United States Esoteric Testing Market Concentration
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United States Esoteric Testing Market News

  • September 2022: Neogen Corporation launched its innovative Veratox VIP assay to detect cashew, the second assay in Neogen's new Veratox VIP line of enhanced quantitative ELISA products.
  • March 2022: Waters Corporation launched the Xevo TQ Absolute system, a highly sensitive and compact benchtop tandem mass spectrometer. As per the company, this latest mass spectrometer is up to 15X more sensitive for quantifying negatively ionizing compounds than its predecessor, is 45% smaller and uses up to 50% less electricity and gas supply.

United States Esoteric Testing Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Prevalence of Chronic and Infectious Diseases
    • 4.2.2 Rising Demand for Early Disease Detection Using Specialized Diagnostic Tests
    • 4.2.3 Increasing Funding and Research Grants for the Development of Innovative Esoteric Tests
  • 4.3 Market Restraints
    • 4.3.1 High Price of Esoteric Testing Procedures
  • 4.4 Porter Five Forces
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION

  • 5.1 By Type
    • 5.1.1 Infectious Diseases Testing
    • 5.1.2 Endocrinology Testing
    • 5.1.3 Oncology Testing
    • 5.1.4 Genetic Testing
    • 5.1.5 Toxicology Testing
    • 5.1.6 Immunology Testing
    • 5.1.7 Neurology Testing
    • 5.1.8 Others
  • 5.2 By Technology
    • 5.2.1 Chemiluminescence Immunoassay
    • 5.2.2 Enzyme-Linked Immunosorbent Assay
    • 5.2.3 Mass Spectrometry
    • 5.2.4 Real-Time PCR
    • 5.2.5 Flow Cytometry
    • 5.2.6 Radioimmunoassay
    • 5.2.7 Other Technologies

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Laboratory Corporation of America
    • 6.1.2 Opko Health Company
    • 6.1.3 Mayo Medical Laboratories
    • 6.1.4 Myriad Genetics
    • 6.1.5 Exact Science Corporation
    • 6.1.6 Avista Capital Partners (Miraca Holdings Inc)
    • 6.1.7 Fulgent Genetics Inc
    • 6.1.8 Invitae
    • 6.1.9 Quest Diagnostic
    • 6.1.10 Nordic Laboratories,
    • 6.1.11 Sonic Healthcare (American Esoteric Laboratories (AEL)),
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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United States Esoteric Testing Industry Segmentation

As per the scope of the report, esoteric testing allows the analysis of rare substances or molecules that are not performed in a routine clinical laboratory. These are additional tests ordered when a physician requires additional detailed information outside routine lab testing to complete a diagnosis, establish a prognosis or choose and monitor a therapeutic regimen. Esoteric testing generally requires sophisticated instruments and materials as well as specialized personnel to perform and analyze results. The United States Esoteric Testing Market is Segmented by Type (Infectious Diseases Testing, Endocrinology Testing, Oncology Testing, Genetic Testing, Toxicology Testing, Immunology Testing, Neurology Testing, and Others) and Technology (Chemiluminescence Immunoassay, Enzyme-Linked Immunosorbent Assay, Mass Spectrometry, Real-Time PCR, Flow Cytometry, Radioimmunoassay, and Other Technologies). The report offers the value in USD (US Dollar) million for the above segments.

By Type Infectious Diseases Testing
Endocrinology Testing
Oncology Testing
Genetic Testing
Toxicology Testing
Immunology Testing
Neurology Testing
Others
By Technology Chemiluminescence Immunoassay
Enzyme-Linked Immunosorbent Assay
Mass Spectrometry
Real-Time PCR
Flow Cytometry
Radioimmunoassay
Other Technologies
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United States Esoteric Testing Market Research FAQs

How big is the United States Esoteric Testing Market?

The United States Esoteric Testing Market size is expected to reach USD 9.10 billion in 2025 and grow at a CAGR of 6.70% to reach USD 12.59 billion by 2030.

What is the current United States Esoteric Testing Market size?

In 2025, the United States Esoteric Testing Market size is expected to reach USD 9.10 billion.

Who are the key players in United States Esoteric Testing Market?

Laboratory Corporation of America Holding, Opko Health Company, Mayo Medical Laboratories, Invitae and Myriad Genetics are the major companies operating in the United States Esoteric Testing Market.

What years does this United States Esoteric Testing Market cover, and what was the market size in 2024?

In 2024, the United States Esoteric Testing Market size was estimated at USD 8.49 billion. The report covers the United States Esoteric Testing Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the United States Esoteric Testing Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

United States Esoteric Testing Industry Report

Statistics for the 2025 United States Esoteric Testing market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. United States Esoteric Testing analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.