Hydroxyzine Imine Market Size & Share Analysis - Growth Trends & Forecasts (2023 - 2028)

The Hydroxyzine Imine Market is Segmented by Dosage Form (Tablets, Capsules, Injection, and Syrup), by Indication Type (Histamine-Mediated Pruritus, Urticaria, and Atopic Contact Dermatoses), and by Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Hydroxyzine Imine Market Size

Hydroxyzine Imine Market Summary
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Study Period 2018 - 2028
Base Year For Estimation 2022
Forecast Data Period 2023 - 2028
CAGR 5.10 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Hydroxyzine Imine Market  Major Players

*Disclaimer: Major Players sorted in no particular order


Need a report that reflects how COVID-19 has impacted this market and its growth?

Hydroxyzine Imine Market Analysis

The hydroxyzine imine market is expected to grow at a significant CAGR of 5.1% during the forecast period.

The COVID-19 pandemic impacted healthcare systems worldwide, exposing vulnerable patients to significant risks, resulting in fewer hospital visits. As a result, the demand for hydroxyzine imine drugs fell. However, during the later phase of the pandemic, research related to the benefits of hydroxyzine imine in COVID-19 patients increased. For instance, as per a research article published in JCM in December 2021, hydroxyzine belongs to the group of functional inhibitors of acid sphingomyelinase (FIASMA), and according to researchers, hydroxyzine could activate various biological processes that are advantageous against COVID-19 and benefit the infected patients, through potential subsequent antiviral and anti-inflammatory effects. Thus, due to such instances, the demand for hydroxyzine drugs increased during later phases of the pandemic. This further fuelled the studied market globally. Hence, the pandemic has shown a considerable impact on the market studied and its growth, which is expected to continue to grow over the analysis period.

Factors such as the increasing allergic reactions among the target population, an increase in investments and awareness campaigns, and a rise in the prevalence of anxiety disorders among the elderly population globally are the major factors that contribute to the market's growth.

The prevalence of allergies or related diseases is increasing globally than the previous few decades. There are several factors that contribute to the rise in cases of allergic conditions. For instance, according to Allergy Facts and Figures updated in April 2022, nearly more than 50 million people in the United States experience various types of allergies every year, and allergies are the sixth major cause of chronic illness in the country. Thus, there is a high burden of allergies in the country, which requires better treatment options.

In this context, according to an article published in IJERPH in November 2021, even though the factors for allergies are clearly unknown, genetic and environmental factors play a significant role in making allergic diseases a major challenge worldwide. Also, several studies suggest that hydroxyzine imine can be used to treat itching caused by allergies. It is an antihistamine that works by blocking certain natural substances, or histamine, that the human body makes during an allergic reaction. Thus, to control the disease burden, the demand for hydroxyzine imine is increasing. Therefore, the high burden of allergies among the target population and the benefits of hydroxyzine imine for allergies are expected to fuel the growth of the market.

Therefore, due to the above-mentioned factors, the market studied is expected to grow significantly during the study period. However, side effects associated with the medication are expected to restrain market growth during the forecast period.

Hydroxyzine Imine Market Trends

This section covers the major market trends shaping the Hydroxyzine Imine Market according to our research experts:

Atopic Contact Dermatitis Segment is Anticipated to Witness Growth Over the Forecast Period

Exposure to a chemical that irritates the skin or sets off an allergic reaction results in atopic contact dermatitis. The material might be one of the tens of thousands of known irritants and allergens. People frequently experience both allergic and irritating reactions simultaneously. The most typical type of contact dermatitis is an irritant. Due to the increasing geriatric population, increase in atopic dermatitis (AD) cases, and other external factors, the prevalence of contact dermatitis is increasing. Thus, the segment is expected to witness growth.

There are several risk factors that contribute to the growth of contact dermatitis, and it is more common in women, children, older people, and people with atopic tendencies. According to the data updated in the NCBI for contact dermatitis in May 2022, contact dermatitis accounts for up to 80% of instances of occupational dermatitis.

In addition, there is an increase in cases of atopic dermatitis (AD) globally, which is another risk factor that creates the contact dermatitis burden. For instance, according to an article published in the journal AMSU in September 2021, an estimated 15% to 20% of all children and 1% to 3% of all adults in developed countries are affected by AD. The source above also stated that, in some developed countries, the incidence of AD has increased by 2 to 3 times in the past decade, and in the first year of life, up to 50% of people with AD have allergic symptoms, and up to 85% begin before the age of five. Thus, the increase in the burden of the disease is generating demand for hydroxyzine imine drugs for effective treatment, driving the segment's growth. Hence, owing to the factors stated above, the studied segment is expected to witness significant growth during the forecast period.

Hydroxyzine Imine Market :Number of Population with Atopic Dermatitis (in %), By Skin color, Race and Ethnicity, United States, 2021

North America is Anticipated to Grow Significantly Over the Forecast Period

North America is expected to witness strong growth over the forecast period. Factors such as high awareness of treatments among the patient population, healthcare infrastructure, early adoption of novel medications, and increasing business partnerships of pharmaceutical companies with contract research organizations in emerging markets are driving the growth of the market in the region.

The major factor fueling the market's growth is the increasing prevalence of atopic dermatitis across the countries of the region, especially in the United States. As per NEA data updated in 2022, an estimated 16.5 million United States adults (7.3%) have atopic dermatitis that initially began at more than two years of age, with nearly 40% affected by moderate or severe disease. Thus, the burden of the disease is increasing the risk of contact dermatitis, which is a major healthcare concern. Thus, hydroxyzine imine is gaining demand for the treatment of such diseases, which is further expected to contribute to market growth.

In addition, the growing number of investments pertaining to eczema and several allergies are contributing to the market's growth. For instance, as per a report by the NIH published in March 2022, the estimated funding for atopic dermatitis research was USD 45 million in 2021 and USD 48 million in 2022. Thus, investments for research purposes in the region are expected to create more favorable opportunities for the development and innovation of hydroxyzine imine drugs. This is expected to drive the market's growth in the United States over the forecast period.

Furthermore, the United States, among other countries, observed a significant increase in the number of campaigns, primarily to raise awareness in society. For instance, Change AD is a campaign managed collaboratively by Sanofi and Regeneron. Every year, the campaign provides awareness about the disease and helps and supports people with AD by addressing bullying or stigma experienced by them. These campaigns are expected to create awareness among the target population for treatment. As a result of the aforementioned factors, the market is expected to grow in North America in the forecast period.

Hydroxyzine Imine Market - Growth Rate by Region

Hydroxyzine Imine Industry Overview

The hydroxyzine imine market is competitive and consists of several major players globally. The key players are developing novel products to compete with the existing products, while others are acquiring and partnering with the other companies trending in the market to expand their global presence. Some of the key players in the market are Teva Pharmaceuticals, Pfizer Inc., GSK PLC, Alliance Pharma, and Piramal Group (Piramal Healthcare UK Limited), among others.

Hydroxyzine Imine Market Leaders

  1. Piramal Healthcare UK Limited

  2. Alliance pharma PLC

  3. Pfizer, Inc

  4. GSK plc

  5. Teva Pharmaceuticals

*Disclaimer: Major Players sorted in no particular order

Hydroxyzine Imine Market Concentration

Hydroxyzine Imine Market News

  • October 2022: LEO Pharma A/S, a global medical dermatology company, launched AD Days Around the World, a global disease awareness campaign that highlights the experiences of people living with atopic dermatitis (AD), a chronic and debilitating skin disease. In partnership with global patient advocate Ashley Ann Lora, the campaign is focused on exploring the impact of AD on the lives of individuals worldwide living with AD.
  • February 2022: Hospitality Allergen Support UK (HASUK), the allergy awareness group, launched a campaign to raise awareness of allergen management.

Hydroxyzine Imine Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increasing Allergic Reaction among the Target Population

      2. 4.2.2 Increase in Investments and Awareness Campaigns

      3. 4.2.3 Increasing Prevalence of Anxiety Disorders among Elderly Population

    3. 4.3 Market Restraints

      1. 4.3.1 Side Effects associated with the Medication

    4. 4.4 Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Dosage Form

      1. 5.1.1 Tablets

      2. 5.1.2 Capsules

      3. 5.1.3 Injection

      4. 5.1.4 Syrup

    2. 5.2 By Indication Type

      1. 5.2.1 Histamine-Mediated Pruritus

      2. 5.2.2 Urticaria

      3. 5.2.3 Atopic Contact Dermatitis

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Teva Pharmaceuticals

      2. 6.1.2 Pfizer, Inc

      3. 6.1.3 GSK, plc

      4. 6.1.4 Alliance Pharma PLC

      5. 6.1.5 Piramal Group (Piramal Healthcare UK Limited)

      6. 6.1.6 Impax Laboratories, Inc

      7. 6.1.7 Novartis AG

      8. 6.1.8 Shanghai Ruizheng Chemical Technology Co., Ltd

      9. 6.1.9 N&R Industries

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments

Hydroxyzine Imine Industry Segmentation

As per the scope of the report, hydroxyzine imine, sold under the brand name Atarax, belongs to a group of medicines called antihistamines, used to treat allergic reactions. It is used in adults and children to reduce itching caused by urticaria (nettle rash) and dermatitis (eczema). Atarax is also used to treat anxiety in adults. The Hydroxyzine Imine Market is Segmented by Dosage Form (Tablets, Capsules, Injection, and Syrup), by Indication Type (Histamine-Mediated Pruritus, Urticaria, and Atopic Contact Dermatoses), and by Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Dosage Form
By Indication Type
Histamine-Mediated Pruritus
Atopic Contact Dermatitis
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Hydroxyzine Imine Market Research FAQs

The Hydroxyzine Imine Market is projected to register a CAGR of 5.1% during the forecast period (2023-2028).

Piramal Healthcare UK Limited, Alliance pharma PLC, Pfizer, Inc, GSK plc and Teva Pharmaceuticals are the major companies operating in the Hydroxyzine Imine Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2023-2028).

In 2023, the North America accounts for the largest market share in the Hydroxyzine Imine Market.

Hydroxyzine Imine Industry Report

Statistics for the 2023 Hydroxyzine Imine market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Hydroxyzine Imine analysis includes a market forecast outlook to 2028 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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