Diphenhydramine Market Size & Share Analysis - Growth Trends & Forecasts (2023 - 2028)

The Diphenhydramine Market is Segmented by Dosage Forms (Tablets, Injection, Powder, Syrups), Application (Allergies, Insomnia, Cold, Nausea, Other Applications), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Diphenhydramine Market Size

Diphenhydramine Market
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Study Period 2018 - 2028
Base Year For Estimation 2022
Forecast Data Period 2023 - 2028
CAGR 2.00 %
Fastest Growing Market Asia-Pacific
Largest Market North America

Major Players

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*Disclaimer: Major Players sorted in no particular order

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Need a report that reflects how COVID-19 has impacted this market and its growth?

Diphenhydramine Market Analysis

The diphenhydramine market is expected to record a CAGR of around 2.0% over the forecast period (2022-2027).

COVID-19 has an impact on many facets of social life, medical procedures, and allergy diagnosis and management. One of the most crucial forms of treatment for IgE-mediated allergies is allergen-specific immunotherapy (AIT), which is based on the diseased person's immunological responses. As a result, the market is expanding because of the rising prevalence of allergies caused by the outbreak. The report published by the University of Florida Health in 2022 under the title 'Two common compounds show effectiveness against COVID-19 virus in early testing' stated that a combination of diphenhydramine and lactoferrin, a protein found in cow and human milk, the combination compounds were found to block the SARS-CoV-2 virus during tests in monkey cells and human lung cells. Moreover, as per the report published in March 2022 under the title 'Antihistamines for Postacute Sequelae of SARS-CoV-2 Infection', histamine antagonists were linked to improved survival and slowed the onset of COVID-19 symptoms in critically ill individuals. These results are likely to cause the adoption of diphenhydramine during COVID-19. Thus, owing to the aforementioned factors COVID-19 had a significant impact on the diphenhydramine market.

An increased number of allergy cases and research and development initiatives in the fields of allergy are boosting the growth of the market. The 2020 update from the Centers for Disease Control and Prevention stated that depending on the allergen, allergic rhinitis symptoms may manifest only during seasons or all year round, affecting as many as 60 million Americans each year. As per the same source, pollen exposure can also trigger symptoms of allergic conjunctivitis. Allergic conjunctivitis is the inflammation of the lining of the eye (conjunctiva) due to exposure to allergens like those in pollen. Up to 30% of the general population and 7 out of 10 people with allergic rhinitis were likely to have allergic conjunctivitis in 2020.

Owing to the aforementioned factors diphenhydramine market is likely to grow over the forecast period. However, the side effect related to diphenhydramine restrains the market growth.

Diphenhydramine Market Trends

This section covers the major market trends shaping the Diphenhydramine Market according to our research experts:

Tablets Form is Estimated to Witness a Healthy Growth Over the Forecast Period.

COVID-19 had a notable impact on the diphenhydramine market. According to the Asthma and Allergy Foundation of America (AAFA), pollen allergies were less in 2020 as a result of COVID-19 restrictions. This was anticipated when many people spent more time indoors and were less exposed to pollen. Children were least affected by seasonal allergies because of fewer outdoor activities and closed schools. The travel limitations and lockdowns remained in effect throughout spring 2021, so there was less exposure to allergy particles. Hence, the COVID-19 pandemic had a significant impact on the tablet segment of the diphenhydramine market.

The tablets form segment is estimated to witness healthy growth in the future, owing to the wide availability of drugs, low cost of manufacturing, ease of administration, and convenience in storage. Tablets are durable, long-lasting, stable, and typically have a longer shelf life than capsules. A single tablet can accommodate a higher dose of an active ingredient than a single capsule. Increasing research and development in the field of allergy are boosting the market growth. For instance, according to Clinicaltrial.gov, there are more than 100 studies currently ongoing for diphenhydramine as of August 2022. With the increased pipeline study related to diphenhydramine and the other aforementioned reasons, the tablet segment is anticipated to increase the market growth over the study period.

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North America is Expected to Hold a Significant Share in the Market and is Expected to do Same over the Forecast Period

North America is expected to hold a significant market share in the global diphenhydramine market, due to the increasing number of allergic populations. For instance, according to the 2022 report from the Asthma and Allergy Foundation of America, around 25 metropolitan areas are under the high-risk category for allergy attacks. Increased initiatives for providing awareness regarding allergy by the government are fueling the market growth. For instance, World Allergy Organization conducted world allergy week in 2022 from June 5th to 11th. The awareness week provides a need for greater attention and provides physicians and the public with a webinar, infographic, and additional information to educate and spread awareness on the allergy. As per the Asthma and Allergy Foundation of America (AAFA), Allergy Capitals Report March 2022, Scranton in Pennsylvania ranked 1 in the allergy population. As per the same source, more than 50 cities are on average at risk for allergy attacks. The same report emphasizes that there is a public health emergency since communities all over the country are experiencing the negative effects of climate change on their health in the United States. Some groups are even more vulnerable. Infants, kids, elders, expectant mothers, people of color, low-income groups, persons with disabilities, and many more who suffer from chronic illnesses like asthma are included in this. Thus, the increasing burden of allergic diseases is expected to aid the demand for diphenhydramine drugs and further propel the growth of the market in this region. Moreover, the increasing healthcare expenditure and the presence of well-established healthcare infrastructure are also fueling the growth of the overall regional market to a large extent.

According to the facts mentioned above diphenhydramine market is expected to grow in the studied region over the forecast period.

Diphenhydramine Market- Growth Rate by Region

Diphenhydramine Industry Overview

The diphenhydramine market is moderately competitive and consists of several major players. Some of the companies which are currently dominating the market are PAI Pharma, Souvin Pharmaceuticals Pvt.Ltd, Pfizer Inc., Johnson & Johnson, and Fresenius Kabi.

Diphenhydramine Market Leaders

  1. Fresenius Kabi

  2. Johnson & Johnson

  3. PAI Pharma

  4. Pfizer Inc.

  5. Souvin Pharmaceuticals Pvt.Ltd

*Disclaimer: Major Players sorted in no particular order

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Diphenhydramine Market News

  • In November 2021 researchers from UF College of Medicine's department of pathology, immunology, and laboratory medicine published that a combination of diphenhydramine and lactoferrin has been found in preliminary tests to inhibit the virus that causes COVID-19.

Diphenhydramine Market Report - Table of Contents

  1. 1. INTRODUCTION

    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study

  2. 2. RESEARCH METHODOLOGY

  3. 3. EXECUTIVE SUMMARY

  4. 4. MARKET DYNAMICS

    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Number of Allergic Population

      2. 4.2.2 Increasing Research and Development Expenditure

    3. 4.3 Market Restraints

      1. 4.3.1 Side Effects of Diphenhydramine

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD Million)

    1. 5.1 By Dosage Forms

      1. 5.1.1 Tablets

      2. 5.1.2 Injection

      3. 5.1.3 Powder

      4. 5.1.4 Syrups

    2. 5.2 By Application

      1. 5.2.1 Allergies

      2. 5.2.2 Insomnia

      3. 5.2.3 Cold

      4. 5.2.4 Nausea

      5. 5.2.5 Other Applications

    3. 5.3 Geography

      1. 5.3.1 North America

        1. 5.3.1.1 United States

        2. 5.3.1.2 Canada

        3. 5.3.1.3 Mexico

      2. 5.3.2 Europe

        1. 5.3.2.1 Germany

        2. 5.3.2.2 United Kingdom

        3. 5.3.2.3 France

        4. 5.3.2.4 Italy

        5. 5.3.2.5 Spain

        6. 5.3.2.6 Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. 5.3.3.1 China

        2. 5.3.3.2 Japan

        3. 5.3.3.3 India

        4. 5.3.3.4 Australia

        5. 5.3.3.5 South Korea

        6. 5.3.3.6 Rest of Asia-Pacific

      4. 5.3.4 Middle East and Africa

        1. 5.3.4.1 GCC

        2. 5.3.4.2 South Africa

        3. 5.3.4.3 Rest of Middle East and Africa

      5. 5.3.5 South America

        1. 5.3.5.1 Brazil

        2. 5.3.5.2 Argentina

        3. 5.3.5.3 Rest of South America

  6. 6. COMPETITIVE LANDSCAPE

    1. 6.1 Company Profiles

      1. 6.1.1 Fresenius Kabi

      2. 6.1.2 Souvin Pharmaceuticals Pvt.Ltd

      3. 6.1.3 PAI Pharma

      4. 6.1.4 Bayer Healthcare

      5. 6.1.5 Pfizer Inc.

      6. 6.1.6 Johnson & Johnson

      7. 6.1.7 S.S.Pharmachem

      8. 6.1.8 Remedy Labs

      9. 6.1.9 Amar Healthcare

      10. 6.1.10 Wan Bury

    2. *List Not Exhaustive
  7. 7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
Competitive Landscape Covers - Business Overview, Financials, Products and Strategies, and Recent Developments

Diphenhydramine Industry Segmentation

As per the scope of the report, diphenhydramine is an antihistamine used to treat allergies, hay fever, and cold. It reduces the effect of the natural chemical histamine in the body. It is also used to prevent nausea, vomiting, and motion sickness. The Diphenhydramine Market is Segmented by Dosage Forms (Tablets, Injection, Powder, Syrups), Application (Allergies, Insomnia, Cold, Nausea, Other Applications), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Dosage Forms
Tablets
Injection
Powder
Syrups
By Application
Allergies
Insomnia
Cold
Nausea
Other Applications
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America

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Diphenhydramine Market Research FAQs

The Global Diphenhydramine Market is projected to register a CAGR of 2% during the forecast period (2023-2028).

Fresenius Kabi, Johnson & Johnson, PAI Pharma, Pfizer Inc. and Souvin Pharmaceuticals Pvt.Ltd are the major companies operating in the Global Diphenhydramine Market.

Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2023-2028).

In 2023, the North America accounts for the largest market share in the Global Diphenhydramine Market.

Global Diphenhydramine Industry Report

Statistics for the 2023 Global Diphenhydramine market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Diphenhydramine analysis includes a market forecast outlook to 2028 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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