G-Protein Coupled Receptors (GPCR) Market - Growth, Trends, COVID-19 Impact, and Forecasts (2021 - 2026)

G-Protein Coupled Receptors (GPCR) Market is Segmented on the basis of Assay Type, Application (Cardiovascular System, Central Nervous System (CNS), OncologyOthers), and Geography

Market Snapshot

G Protein Coupled Receptors Gpcr Market Overview
Study Period: 2018 - 2026
Base Year: 2020
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 6.8 %
G Protein Coupled Receptors Gpcr Market Key Players

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Market Overview

G-protein coupled receptors market is anticipated to be driven by rising number of cancer cases, rising prevalence of lifestyle-related issues, such as cardiovascular infections, and respiratory issues. G-protein coupled receptors (GPCRs) are exceptionally helpful in the innovative work of newer medication substances. Furthermore, the increasing government funding for R&D activities in drug discovery and development is anticipated to drive the market growth. Additionally, the functional and structural literature on the pharmacological components of the GPCRs is demonstrating the adaptable utilities of GPCRs targets in the treatment of an expansive range of disorders which helps the market expand. The high cost involved in the maintenance of GPCR cell lines impedes the growth of the G-protein coupled receptors (GPCR) market.

Scope of the Report

G-protein coupled receptor (GPCR), also called seven-trans membrane receptor or heptahelical receptor, is a protein located in the cell membrane that binds extracellular substances and transmits signals from these substances to an intracellular molecule called a G protein (guanine nucleotide-binding protein). GPCRs are found in the cell membranes of a wide range of organisms, including mammals, plants, microorganisms, and invertebrates. Some examples of GPCRs include beta-adrenergic receptors, which bind epinephrine, prostaglandin E2 receptors, which bind inflammatory substances called prostaglandins, and rhodopsin, which contains a photo reactive chemical called retinal, which responds to light signals received by rod cells in the eye.

By Assay Type
Calcium Level Detection Assays
Radioligand Binding and GTPγS Functional Assays
cAMP Assays and cGMP Assays
β-Arrestin Functional Assays
Reporter Gene Assays
Other Assay Types
By Application
Cardiovascular System
Central Nervous System (CNS)
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle East & Africa
South Africa
Rest of Middle East & Africa
South America
Rest of South America

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Key Market Trends

Oncology Estimated to Dominate the Global G-Protein Coupled Receptors (GPCR) Market, by Therapeutic Areas

More than 700 genes are identified as the G-protein coupled receptors, which form the largest protein superfamily in the human genome. GPCRs play a vital role in interfering with a wide variety of physiological events, from sensory modulations to hormonal responses. Recently, a key focus on basic and clinical investigators demonstrated that signaling through GPCRs affects the various aspects of cancer biology, such as invasion, migration, and vascular remolding. Hence, the development of GPCR-targeted drugs will provide a novel therapeutic strategy in treating various types of cancers. As GPCR signaling is an important contributor to tumor growth and metastasis, discerning how G protein-coupled receptor kinases (GRKs) regulate GPCR activity in cancer cells may greatly improve the understanding of tumorigenesis and oncogenesis, and help develop novel anti-cancer therapies.

G Protein Coupled Receptors Gpcr Market Key Trends

Asia-Pacific is Anticipated to Register a Rapid CAGR

The Asia-Pacific region is expected to grow at a significant rate during the forecast period, owing to the economic development of the countries, such as China and India, along with the increasing government investment in the biotechnology and biopharmaceutical sector, increasing life expectancy, rising per capita income, and unmet market needs in the region. Additionally, Asia Pacific is anticipated to be the fastest-growing regional market due to the presence of several emerging companies, such as Sosei Heptares, and NB Health Laboratory. The number of growth initiatives undertaken by the companies to improve their market presence drives regional growth.

G Protein Coupled Receptors Gpcr Market Growth Rate

Competitive Landscape

The players in global G-protein coupled receptors (GPCR) market are focusing on the expansion of their product portfolios, by adopting inorganic growth strategies, such as acquisitions, mergers, and partnerships. For instance, in June 2018, Amgen's erenumab secured the FDA approval as the first G-protein coupled receptor-targeted antibody. Despite various challenges, several biologics are under the manufacturing process. 

Table of Contents


    1. 1.1 Study Deliverables

    2. 1.2 Study Assumptions

    3. 1.3 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Demand for GPCR assays in Drug Discovery Studies

      2. 4.2.2 Wide Range Applications of GPCRs in the Treatment for Various Medical Conditions

      3. 4.2.3 Increasing prevalence of chronic Diseases

    3. 4.3 Market Restraints

      1. 4.3.1 Challenges with the purification of GPCRs

      2. 4.3.2 Complexity of the GPCR Signalling System

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Assay Type

      1. 5.1.1 Calcium Level Detection Assays

      2. 5.1.2 Radioligand Binding and GTPγS Functional Assays

      3. 5.1.3 cAMP Assays and cGMP Assays

      4. 5.1.4 β-Arrestin Functional Assays

      5. 5.1.5 Reporter Gene Assays

      6. 5.1.6 Other Assay Types

    2. 5.2 By Application

      1. 5.2.1 Cardiovascular System

      2. 5.2.2 Central Nervous System (CNS)

      3. 5.2.3 Oncology

      4. 5.2.4 Others

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle East & Africa

        1. GCC

        2. South Africa

        3. Rest of Middle East & Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Abcam PLC

      2. 6.1.2 Becton, Dickinson and Company

      3. 6.1.3 PerkinElmer Inc.

      4. 6.1.4 Merck KGaA

      5. 6.1.5 Enzo Biochem Inc. (Enzo Life Sciences Inc.)

      6. 6.1.6 Danaher Corporation (Molecular Devices LLC)

      7. 6.1.7 Promega Corporation

      8. 6.1.8 Bioinvenu Corporation

      9. 6.1.9 Thermo Fisher Scientific Inc.

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The G-Protein Coupled Receptors (GPCR) Market market is studied from 2018 - 2026.

The G-Protein Coupled Receptors (GPCR) Market is growing at a CAGR of 6.8% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

Abcam PLC, Enzo Life Sciences Inc., Promega Corporation, PerkinElmer Inc., Thermo Fisher Scientific Inc. are the major companies operating in G-Protein Coupled Receptors (GPCR) Market.

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