Desalting And Buffer Exchange Market Size
| Study Period | 2019 - 2030 |
| Base Year For Estimation | 2024 |
| Forecast Data Period | 2025 - 2030 |
| CAGR | 10.10% |
| Fastest Growing Market | Asia-Pacific |
| Largest Market | North America |
| Market Concentration | Medium |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Desalting And Buffer Exchange Market Analysis
The Desalting And Buffer Exchange Market is expected to register a CAGR of 10.1% during the forecast period.
The COVID-19 pandemic impacted the desalting & buffer exchange market initially. The sudden outbreak and massive numbers of COVID-19 infections created an unprecedented demand for research and development of therapeutic, vaccines, and diagnostic assays for managing COVID-19. The R&D of the COVID-19 diagnosis and therapeutics required desalting & buffer exchange products, which resulted in a hike in demand for the desalting & buffer exchange products in the downstream process amid the pandemic. Several research studies related to SARS-CoV-2 protein or nucleic acid extraction, diagnosis, and therapeutic development mentioned the use of desalting & buffer exchange products. For instance, according to the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA), in 2021, 11 billion COVID-19 vaccines were produced, and nearly 200 vaccine candidates were in the production pipeline. The desalting and buffer exchange products were extensively used in the vaccine production process as the buffer exchange is an important step in the downstream process. Thus, the pandemic had a favorable impact on the market initially; however, with the decrease in COVID-19 cases and the resumption of R&D for non-COVID-19 indications, the market is growing normally. It will continue the trend over the forecast period as well.
The increasing research and development by biopharmaceutical industries and the rising focus on proteomic and genomic research are the major drivers for the market.
The increasing demand for biopharmaceutical products, coupled with the rise in research and development expenditure on biopharmaceutical products, is one of the key drivers for the market. For instance, as per the data published by the European Federation of Pharmaceutical Industries and Associations' Annual Report 2022, the value of production for the research-based European pharmaceutical industry increased in the past years, and it reached the value of EUR 300.0 billion (USD 321.21 billion) in 2021. Such an initiative is expected to increase the production of drugs and related research works. Since desalting and buffer exchange play an important role in the downstream production process of drugs, the increasing expenditure on the research and development of biopharmaceuticals is expected to boost the market's growth over the forecast period.
Additionally, the increasing investment by the market players in the research and development of products and facilities is expected to boost the R&D and manufacturing of vaccines, which is also expected to elevate the demand for desalting and buffer exchange products in the coming years. For instance, in April 2022, Thermo Fisher Scientific opened its new single-use technology manufacturing site in Utah, the United States. The state-of-the-art facility will be more capable of manufacturing the high-quality technology and materials needed to develop new vaccines and breakthrough therapies. The facility will manufacture highly customizable bioprocess container (BPC) systems. Similarly, in December 2022, Pfizer invested over USD 750.0 million in expanding the Michigan pharmaceutical manufacturing plant in the United States to elevate the production of vaccines and medicines using mRNA technology. Hence, such investments by the market players are expected to drive the demand for purification processes of the final products, which essentially require desalting and buffer exchange products, thereby boosting the market growth over the forecast period.
Therefore, owing to the increasing investment in R&D and strategic initiatives by the key players related to the market, considerable market growth is expected over the forecast period.
However, the lack of skilled professionals may impede the market growth over the forecast period.
Desalting And Buffer Exchange Market Trends
The Pharmaceutical and Biotechnology Industries Segment is Expected to Witness Significant Growth Over the Forecast Period
The pharmaceutical and biotechnology industry segment is anticipated to grow with the advancing research and development activities and investments in the pharmaceutical and biotechnology domain.
The increase in research and developmental activities in the pharmaceutical and biotechnology industries to manufacture biopharmaceutical products may increase the demand for desalting and buffer exchange systems. For instance, as per the January 2023 update by the U.S. FDA, in 2022, 37 novel drugs were approved by the FDA. Since desalting and buffer exchange allow the separation of macromolecules from relatively smaller molecules, a crucial step in downstream processing to attain the final products, an increase in novel drug development by pharmaceutical and biotechnology companies is expected to drive the segment growth.
Furthermore, several pharmaceutical and biotechnology companies have taken strategic decisions to elevate the R&D and manufacturing of pharmaceuticals, which may surge the demand for desalting and buffer exchange products. For instance, in October 2022, Johnson & Johnson and Legend Biotech stated that they plan to increase their investments by twofold to USD 500.0 million to elevate the manufacturing of CAR-T cancer therapy. Similarly, in September 2022, Novartis invested over USD 300.0 million in biotherapeutics to create a fully integrated scientific environment to bolster its capacity and capabilities for early technical biologics development. Thus, such investments are expected to accelerate drug development. Therefore, the increasing expenditure on research and development and the recent developments by the biopharmaceutical and biotechnology industries to develop their pipeline products are expected to boost the segment growth over the forecast period.
Therefore, the pharmaceutical and biotechnology industry segment is expected to witness significant growth over the forecast period due to advancing research and development activities and rising investments by the pharmaceutical and biotechnology sectors.
North America is Expected to Witness Significant Growth Over the Forecast Period
North America is expected to witness healthy growth due to increasing demand for biopharmaceuticals and rising research and development expenditure by biopharmaceutical companies in the region. The region has significantly high R&D investment in biopharmaceuticals, which is anticipated to boost the demand for desalting & buffer exchange products as these products are utilized in the downstream processing of therapeutic biopharmaceuticals. For instance, as per the data published by the Pharmaceutical Research and Manufacturers of America in July 2022, the PhRMA member companies invested over 102.3 billion in the R&D of biopharmaceuticals for chronic and rare conditions in 2022. The same source further stated that it was the highest level of investment on record. Furthermore, the government of Canada has also been investing in the biomanufacturing, vaccine, and therapeutics ecosystem. For instance, the government of Canada invested over CAD 32.7 million (USD 24.4 million) into Novocol Pharmaceutical of Canada to expand the biomanufacturing capacity of Novocol's vaccines or therapeutics manufacturing and packaging for distribution.
The United States is expected to witness considerable growth among other countries of the North American region. The increasing focus by the market players on the research and development of cell biology products in the country is expected to propel the demand for desalting & buffer exchange products. For instance, in July 2022, Cytiva, in collaboration with Pall Corporation, invested over USD 1.5 billion to build its first chromatography resin plant outside Sweden. The company acquired a facility in Michigan in the United States, where the resin will be produced and used to purify and analyze biomolecules. Cytiva will get support from the State of Michigan and several United States agencies, including the Biomedical Advanced Research and Development Authority. Such investment by the market players and support from the public authorities is expected to contribute to the market growth over the forecast period.
Therefore, the increasing expenditure on research and development by the biopharmaceutical and biotechnology industries is expected to boost the growth of the North American region's desalting and buffer exchange market.
Desalting And Buffer Exchange Industry Overview
The desalting and buffer exchange market is moderately competitive and has several major players. A few of the major players are currently dominating the market in terms of market share. Some of the companies which are currently dominating the market are ThermoFisher Scientific, Sartorius AG, Merck KGaA, Agilient Technologies Inc., Repligen, PhyNexus, Inc, Biogen, Norgen Biotec Corp., Danaher, and others.
Desalting And Buffer Exchange Market Leaders
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Sartorius AG
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Merck KGaA
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Danaher Corporation (Cytvia)
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Agilient Technologies, Inc.
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Thermo Fisher Scientific Inc.
- *Disclaimer: Major Players sorted in no particular order
Desalting And Buffer Exchange Market News
- January 2023: Sartorius extended a strategic collaboration partnership agreement with RoosterBio Inc. to address purification challenges and establish scalable downstream manufacturing processes for exosome-based therapies. The collaboration would strengthen the bioprocessing portfolio of the company.
- June 2022: Global analytical science and device company Trajan Group Holdings Limited signed a binding share purchase agreement and a real estate purchase agreement to acquire 100% of Chromatography Research Supplies, Inc. (CRS), one of the leading global manufacturers of high-quality analytical consumables based in Kentucky, USA.
- February 2022: Sartorius, through its subgroup Sartorius Stedim Biotech, acquired the Novasep chromatography division following approval by the United States Federal Trade Commission.
Desalting And Buffer Exchange Industry Segmentation
As per the report's scope, desalting occurs when buffer salts and other molecules are removed from a sample in exchange for water. Buffer exchange occurs when the buffer salts in a sample are exchanged for those in another buffer. The Desalting and Buffer Exchange market is segmented by Product (Cassettes and Cartridges, Kits, Filter Plates, and Other Products), Technique (Filtration, Chromatography, and Precipitation), Application ( Bioprocess Application, Diagnostic Application, Pharmaceutical and Biotechnology Industries, and Other Applications) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Market report also covers the estimated market sizes and trends of 17 countries across major regions globally. The report offers the value (in USD) for the above segments.
| By Product | Cassettes and Catridges | ||
| Kits | |||
| Filter plates | |||
| Other Products | |||
| By Technique | Filtration | ||
| Chromatography | |||
| Precipitation | |||
| By Application | Pharmaceutical and Biotechnology Industries | ||
| Diagnostic Applications | |||
| Other Applications | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Middle East and Africa | GCC | ||
| South Africa | |||
| Rest of Middle East and Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
Desalting & Buffer Exchange Market Research FAQs
What is the current Global Desalting and Buffer Exchange Market size?
The Global Desalting and Buffer Exchange Market is projected to register a CAGR of 10.1% during the forecast period (2025-2030)
Who are the key players in Global Desalting and Buffer Exchange Market?
Sartorius AG, Merck KGaA, Danaher Corporation (Cytvia), Agilient Technologies, Inc. and Thermo Fisher Scientific Inc. are the major companies operating in the Global Desalting and Buffer Exchange Market.
Which is the fastest growing region in Global Desalting and Buffer Exchange Market?
Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in Global Desalting and Buffer Exchange Market?
In 2025, the North America accounts for the largest market share in Global Desalting and Buffer Exchange Market.
What years does this Global Desalting and Buffer Exchange Market cover?
The report covers the Global Desalting and Buffer Exchange Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Desalting and Buffer Exchange Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
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Global Desalting and Buffer Exchange Industry Report
Statistics for the 2025 Desalting And Buffer Exchange market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Desalting And Buffer Exchange analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
