Blood Group Typing Market Size & Share Analysis - Growth Trends And Forecast (2025 - 2030)

Global Blood Group Typing Market Trends and Insights

Growth in Global Blood Transfusion Procedures

Worldwide transfusion volumes continue to climb as complex cardiovascular, trauma, and oncological interventions become commonplace. Each transfusion episode triggers multiple compatibility checks, so even marginal increases in procedure counts magnify reagent and instrument demand. Emergency medicine now requires point-of-care analyzers that can process ABO-Rh typing in under five minutes, a capability that high-volume hospitals in the United States and Japan already view as essential^{[3]Pan American Health Organization, “Blood,” paho.org}. Automated workflows are therefore replacing manual tube testing in both tertiary centers and regional trauma networks.

Rising Prevalence of Chronic and Hematological Disorders

Long-term transfusion support for thalassemia, sickle cell disease, and hematologic cancers is reshaping routine practice from basic ABO-Rh matching to extended antigen phenotyping. Molecular assays that read multiple blood group loci in a single run limit alloimmunization, a risk especially acute in multi-transfused pediatric patients. Oncology protocols are also adopting prophylactic typing to offset transfusion reactions during chemotherapy cycles.

Expansion of National Blood Donation Programs

Pursuit of 100% voluntary donation—as advocated by the World Health Organization—has prompted new collection centers across India, Indonesia, and Nigeria to procure fully automated analyzers, refrigerated centrifuges, and LIS-connected barcode readers. Emerging economies often purchase turnkey reagent-instrument bundles, benefiting vendors that offer scalable platforms able to process hundreds of samples per shift while maintaining strict quality metrics.

Technological Advancements in Automated Blood Typing Systems

Robotics, machine vision, and middleware now combine to produce closed-tube, walk-away analyzers that curtail transcription errors and address a 9.25% vacancy rate for laboratory technologists in the United States. Real-time result validation with AI algorithms is beginning to flag aberrant reaction patterns, freeing technologists for complex problem-solving rather than routine pipetting.

Limited Healthcare Infrastructure in Low-Income Regions

Inconsistent electricity, inadequate cold chain capacity, and scarce maintenance expertise hamper reliable blood typing in a sizable share of African and rural South Asian facilities. Cap-ex hurdles slow adoption of NGS and even mid-tier automated serology systems, compelling many centers to rely on manual slide or rapid card tests with lower sensitivity.

Shortage of Skilled Laboratory Personnel

Accelerated retirements coupled with weak enrollment in medical laboratory programs restrict the number of qualified immunohematology technologists. Smaller hospitals struggle to staff 24-hour transfusion services, limiting in-house ability to manage complex antibody work-ups. Facilities frequently outsource advanced molecular typing to reference laboratories, stoking demand for send-out services but delaying real-time decision making in some care settings.

Segment Analysis

By Product – Services Outpace a Consumables-Dominated Base

Consumables accounted for 48.32% of blood typing market share in 2024, reflecting the high frequency of reagents used for routine gel card and microplate testing. The services category, however, is projected to post a 10.45% CAGR to 2030 as laboratories increasingly outsource NGS-based antigen panels and rare antibody identification. That outsourcing trend enlarges the blood typing market size for specialized reference providers, many of which package logistics, sequencing, and interpretive reports under subscription agreements. Instruments maintain mid-single-digit growth, driven by upgrades to AI-enabled analyzers that optimize reagent use and interface directly with hospital LIS platforms.

Laboratory managers cite the capital-intensive nature of NGS as the main reason for send-out adoption. Meanwhile, reagent suppliers face price pressure as automated analyzers become more frugal with micro-volume reaction pads. Despite that, rising total test volumes secure stable revenue streams for gel cards, buffers, and control sera. Instrument manufacturers differentiate through modular designs that expand from 96 to 384 well formats, aligning capacity with fluctuating seasonal demand.

Note: Segment shares of all individual segments available upon report purchase

By Technique – NGS Redefines the Molecular Frontier

PCR and microarray platforms delivered 37.23% of segment revenue in 2024, yet NGS is forecast to climb at a 12.45% CAGR, reflecting unrivaled depth of antigen coverage. The blood typing market size for NGS reagents is still below traditional serology reagents, but rapid uptake in reference centers is narrowing the gap. Multi-locus sequencing resolves Rh, Kell, Kidd, and Duffy variants in a single assay, which supports precision-matching policies for chronically transfused patients.

While serology remains the frontline workhorse for same-day ABO-Rh testing, clinicians now consider NGS confirmation indispensable for complex phenotyping. Microfluidics and lateral-flow cassettes keep a foothold in resource-constrained or emergency settings due to minimal training requirements. Hybrid workflows are therefore common: a slide or column agglutination test confirms immediate compatibility, with NGS data arriving a day later to refine extended match decisions.

By Test Type – Antigen Typing Accelerates Beyond ABO Dominance

ABO grouping generated 41.67% of 2024 revenues, a testament to its universal clinical necessity. Antigen typing nonetheless is projected for an 11.56% CAGR through 2030, outpacing the broader blood typing market. This trajectory stems from wider use of prophylactic phenotype matching in hemoglobinopathy care, where alloimmunization risk climbs after multiple transfusions. Cross-matching and antibody screening continue to anchor peri-operative protocols, yet hospitals now layer molecular antigen panels on top to ensure long-term compatibility.

The blood typing market size tied to antigen typing also benefits from prenatal testing, where fetal RHD genotyping guides anti-D immunoglobulin use. Manufacturers responding to this shift emphasize multiplex assay kits that cover 30+ clinically significant antigens without increasing sample input volumes. LIS-driven reflex rules then move positive screens straight into extended work-ups, preserving turnaround time.

Note: Segment shares of all individual segments available upon report purchase

By End User – Diversified Demand Beyond Hospital Labs

Hospitals held 52.86% of overall revenue in 2024, yet diagnostic laboratories, blood collection facilities, and academic centers are projected for the fastest 13.67% CAGR. Outsourcing by community hospitals funnels a growing number of samples into national reference labs, where high-throughput analyzers leverage economies of scale. Research institutions pursue grant-funded projects on blood group genomics, boosting demand for NGS library prep kits and bespoke bioinformatics pipelines.

Blood banks are deploying automated grouping instruments to accelerate donor unit release, integrating barcoded reagent packs and auto-validation middleware that synch with donor management software. This workflow modernization makes it possible to complete collection-to-issue cycles in under 24 hours, a target set by many national transfusion services.

Geography Analysis

North America controlled 33.45% of revenue in 2024 thanks to stringent regulatory oversight, high healthcare spending, and a mature hospital network that prioritizes fully automated immunohematology. FDA clearances in 2025 for integrated serology-molecular workstations illustrate the region’s appetite for technology that merges gel card processing with reflex NGS and AI-based interpretation. A tight labor market further accelerates instrument replacement cycles, as labs gravitate to walk-away analyzers that need fewer hands-on minutes.

Asia-Pacific is forecast to post the highest 8.92% CAGR through 2030. National blood donation expansion across India, Indonesia, and Vietnam is pouring large sample volumes into both public and private testing channels, while China is fast-tracking automated reagent rental programs in provincial centers. Japan holds the highest per-capita test penetration, driven by rapid uptake of molecular typing for oncology and transplantation. Local manufacturers in South Korea and China are entering the mid-range instrument tier, challenging Western incumbents on price and after-sales service.

Europe maintains steady mid-single-digit growth. Harmonized EU medical device regulations impose rigorous performance verification, yet reimbursement frameworks in Germany, France, and the Nordics support adoption of high-spec analyzers that reduce sample volume and waste. Meanwhile, the Middle East and Africa display uneven progress. Gulf Cooperation Council countries import top-end instruments for tertiary hospitals, whereas many sub-Saharan facilities rely on manual slide testing due to power instability. South America gains momentum as Brazil’s hemovigilance reforms channel capital into centralized testing hubs that serve multiple states.