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The market is segmented by Therapy, Route of Administration (Oral, Parenteral, Other Routes of Administration), Disease, and Geography.
Fastest Growing Market:
The market for hormone replacement therapy is expected to witness a CAGR of approximately 6.5%, over the forecast period. Certain factors that are positively affecting the market growth are increasing awareness on post-menopausal issues among women, rise in drug development with novel delivery systems, and hormonal imbalance disorders with rising geriatric population.
Hormonal imbalance disorders, with an increase in the geriatric population, is one of the major factors responsible for the growth of the market studied. With various kinds of hormonal changes, the female body predominantly gets affected by the natural process of aging, leading to abnormalities and diseases. Some of the common problems include weight gain, memory decline, fatigue, low libido, aging appearance, and muscle loss.
The most frequently reported consequence of age-related hormonal changes occurs in cases related to menopause. The global average onset age for menopause among women is approximately 50 years. In women, by the age of 50 years and above, the production levels of estrogen and progesterone decrease significantly. The decrease in production levels of estrogen and progesterone are compensated by the pituitary gland, with the increased production of follicle stimulating hormone (FSH). This is physically manifested in women in the form of post-menopause symptoms, which include flush. In the United States, up to 10% of women are diagnosed with polycystic ovary syndrome (PCOS), nearly 6% of married women below the age of 45 years suffer from infertility, and nearly 8% men under the age of 45 years receive fertility treatment during their lifetime.
These factors associated with age lead to the rising demand for HRT, thus driving the market studied.
Hormone replacement therapy (HRT) is a treatment technique for replacing and/or replenishing hormones in the human body, which are at inadequate levels than those required for the normal physiology of the human body. The most prominent application of HRT is in the treatment of symptom alleviation of menopause.
|Estrogen Hormone Replacement|
|Growth Hormone Replacement|
|Thyroid Hormone Replacement|
|By Route of Administration|
|Other Routes of Administration|
|Growth Hormone Deficiency|
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The most common form of estrogen replacement therapy (ERT) is oral medication. Besides, ERT is also available in the commercial market, in the form of pills, patches, and suppositories.
The most prominently consumed oral ERT variants include conjugated estrogens (Premarin), estradiol (Estrace), and Estratab. ERTs are an effective treatment option for female patients suffering from menopause symptoms. However, there are several side effects associated with the usage of ERTs. Oral ERTs are associated with strokes, blood clots, and some cases of cancer. These side effects have been well documented in the form of moderate-severe adverse drug reactions (ADRs).
These ADRs are expected to cause some erosion in the popularity of ERTs. However, their adoption rate is expected to increase over the forecast period, globally, due to the increasing prevalence of hormonal imbalance issues among the geriatric people and pregnant women.
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Rising geriatric population is one of the primary factors responsible for the growth of the hormonal replacement therapy market in the United States.
According to the National Institutes of Health (NIH), almost half of all the postmenopausal women in the United States reported having used HRT at least once in their life. The conjugated equine estrogens (CEE)/bazedoxifene tablet, a combination of estrogen and a selective estrogen receptor modulator, is available in the United States for menopausal VMS treatment and osteoporosis prevention.
Three organizations, namely, the American College of Obstetricians and Gynecologists, the North American Menopause Society (NAMS), and the Endocrine Society, have produced guidelines on the use of HRT during menopause. As of 2016, there were 15 producers of estrogens and eight producers of progestins. In 2016, the top-selling HRT-based drug was Premarin, with a market share greater than 50% among HRTs. Consequently, Premarin became the fifth most prescribed drug in the country.
Overall, the market for HRT in the United States is scheduled for high growth over the forecast period. The major drivers of this market are expected to increase the adoption of HRT among women, for both post-menopausal and menopause management.
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The market is consolidated. Several companies with the largest market share are Abbott, Bayer AG, Merck KGaA, Novartis AG, and Pfizer Inc. However, there are efforts being made by new players to enter the hormone replacement therapy market.
1.1 Study Deliverables
1.2 Study Assumptions
1.3 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Increasing Awareness on Post-menopausal Issues among Women
4.2.2 Rise in Drug Development with Novel Delivery Systems
4.2.3 Hormonal Imbalance Disorders with Rising Geriatric Population
4.3 Market Restraints
4.3.1 High Cost of Hormone Replacement Therapy
4.3.2 Substantial Risk of Cancer Associated with Hormone Replacement Therapy
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION
5.1 By Therapy
5.1.1 Estrogen Hormone Replacement
5.1.2 Growth Hormone Replacement
5.1.3 Thyroid Hormone Replacement
5.1.4 Testosterone Replacement
5.2 By Route of Administration
5.2.3 Other Routes of Administration
5.3 By Disease
5.3.3 Growth Hormone Deficiency
5.3.4 Other Diseases
5.4.1 North America
184.108.40.206 United States
220.127.116.11 United Kingdom
18.104.22.168 Rest of Europe
22.214.171.124 South Korea
126.96.36.199 Rest of Asia-Pacific
5.4.4 Middle East & Africa
188.8.131.52 South Africa
184.108.40.206 Rest of Middle East & Africa
5.4.5 South America
220.127.116.11 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Abbott Laboratories
6.1.2 Bayer AG
6.1.3 Eli Lilly and Company
6.1.4 F. Hoffmann-La Roche
6.1.5 Hisamitsu Pharmaceutical Co. Inc.
6.1.6 Merck KGaA
6.1.7 Mylan NV
6.1.8 Novartis AG
6.1.9 Novo Nordisk AS
6.1.10 Pfizer Inc.
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments