Hepatorenal Syndrome Treatment Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The Hepatorenal Syndrome Treatment Market is segmented by Treatment(Therapeutics, Liver Transplantation, Surgical Shunting, Renal Replacement Therapy, Others) and by Geography.

Market Snapshot

Study Period: 2018 - 2026
Base Year: 2021
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 6.2 %

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Market Overview

The hepatorenal syndrome treatment market is projected to record a CAGR of nearly 6.2% over the forecast period. Hepatorenal syndrome is a type of progressive kidney failure seen in people with severe liver damage, most often caused by cirrhosis. As the kidneys stop functioning, toxins begin to build up in the body. Eventually, this leads to liver failure. The major factor attributing to the growth of the market is the increase in the prevalence of liver damage and cirrhosis. According to the Centers for Disease Control and Prevention, 4.5 million adults are diagnosed with chronic liver disease in the year 2018, in the United States alone. Furthermore, increasing fast-track and orphan drug designations boosts the market growth. However, side effects with the drugs and stringent regulations are restraining the market growth.

Scope of the Report

Hepatorenal syndrome is the development of renal failure in patients with advanced chronic liver disease. This report is segmented by treatment, and by geography.

By Treatment
Liver Transplantation
Surgical Shunting
Renal Replacement Therapy
Other Treatments
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Key Market Trends

Therapuetics Segment is the Fastest Growing Segment of the Hepatorenal Syndrome Treatment Market.

The therapeutics segment is expected to grow at a greater phase as the patients prefer taking drugs than undergoing surgeries. Furthermore, increasing fast track and orphan designations to the drugs is further boosting the segment. Several drugs have received orphan drug designation, thereby accelerating their approval process, and this can act as a factor pushing the growth of the therapeutics segment. For instance, in November 2018, BioVie Inc. announced that the FDA granted Orphan Drug designation to its Terlipressin drug for the treatment of the hepatorenal syndrome. The designation for orphan drugs allows manufacturers to qualify for various incentives, including tax credits for qualified clinical trials, along with seven years of market exclusivity upon regulatory approval. This is likely to drive the hepatorenal syndrome treatment market during the forecast period.

fast track

North America Dominates the Market and is Expected to do the Same in the Forecast Period

North America is expected to dominate the overall market, throughout the forecast period. The market growth is due to the factors, such as the presence of key players, established healthcare infrastructure, increased prevalence of severe liver damage and cirrhosis are some of the key factors accountable for its large share in the market. Furthermore, beneficial government initiatives and an increase in the number of research partnerships are some of the drivers expected to increase the market growth. In this region, the United States has the maximum share due to supportive healthcare policies, high number of patients, and a developed healthcare market. According to the US Department of Health and Human Services,1 in 400 adults in the United States has cirrhosis for the year 2018. As per the statistics the increasing patient pool and increasing disposable revenue in this country boost the market growth of the region.


Competitive Landscape

The hepatorenal syndrome treatment market is moderately competitive and consists of several major players. Some of the companies which are currently dominating the market are Cumberland Pharmaceuticals Inc., Mallinckrodt Pharmaceuticals, New Medicon Pharma Lab, Becton, Dickinson and Company, Edwards Lifesciences Corporation, Aetna Inc.,Baxter, Fuji Systems Corp, Johnson & Johnson Co, G Surgiwear Ltd.

Table of Contents


    1. 1.1 Study Deliverables

    2. 1.2 Study Assumptions

    3. 1.3 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increasing Prevalence of Severe Liver Damage Which Often Leads to Hepatorenal Syndrome

      2. 4.2.2 Increasing Fast Track and Orphan Drug Designations

    3. 4.3 Market Restraints

      1. 4.3.1 Side-effects and Risks Related to Drug Usage

      2. 4.3.2 Stringent Regulatory Requirements

    4. 4.4 Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Treatment

      1. 5.1.1 Therapeutics

      2. 5.1.2 Liver Transplantation

      3. 5.1.3 Surgical Shunting

      4. 5.1.4 Renal Replacement Therapy

      5. 5.1.5 Other Treatments

    2. 5.2 Geography

      1. 5.2.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.2.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.2.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.2.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.2.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Cumberland Pharmaceuticals Inc.

      2. 6.1.2 Mallinckrodt Pharmaceuticals

      3. 6.1.3 New Medicon Pharma Lab

      4. 6.1.4 Becton, Dickinson and Company

      5. 6.1.5 Edwards Lifesciences Corporation

      6. 6.1.6 Aetna Inc.

      7. 6.1.7 Baxter

      8. 6.1.8 Fuji Systems Corp

      9. 6.1.9 Johnson & Johnson Co

      10. 6.1.10 G Surgiwear Ltd

    2. *List Not Exhaustive

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The Hepatorenal Syndrome Treatment Market market is studied from 2018 - 2026.

The Hepatorenal Syndrome Treatment Market is growing at a CAGR of 6.2% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2021.

Cumberland Pharmaceuticals Inc. , Mallinckrodt Pharmaceuticals, New Medicon Pharma Lab, Becton, Dickinson and Company, Edwards Lifesciences Corporation are the major companies operating in Hepatorenal Syndrome Treatment Market.

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