Preclinical Imaging Market Size and Share
Preclinical Imaging Market Analysis by Mordor Intelligence
The Preclinical Imaging Market size is estimated at USD 4.46 billion in 2025, and is expected to reach USD 5.61 billion by 2030, at a CAGR of 4.71% during the forecast period (2025-2030).
Momentum is anchored in rising adoption of AI-powered multimodal systems, sustained pharmaceutical R&D spending, and steady public investment in imaging infrastructure. Optical modalities continue to dominate because of their lower cost and real-time visualization advantages, yet hybrid platforms are gaining traction as researchers seek richer datasets in a single session. Contract research organizations (CROs) command growing attention, offering turnkey access to cutting-edge equipment and regulatory know-how that many drug developers lack in-house. North America remains the epicenter of demand, but Asia’s rapid infrastructure build-out is closing the gap and reshaping global supply chains in the preclinical imaging market.
Key Report Takeaways
- By modality, optical systems led with 35.32% revenue share in 2024, while hybrid and multimodal platforms are projected to advance at a 9.82% CAGR to 2030.
- By application, oncology held 40.14% of the preclinical imaging market share in 2024; neurology is forecast to expand at a 10.31% CAGR through 2030.
- By end user, pharmaceutical and biotechnology companies accounted for 45.61% of the preclinical imaging market size in 2024, whereas CROs post the fastest CAGR at 11.91% during 2025-2030.
- By geography, North America captured 48.18% of the preclinical imaging market in 2024; Asia Pacific is set to grow at a 9.53% CAGR out to 2030.
Global Preclinical Imaging Market Trends and Insights
Drivers Impact Analysis
| Driver | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
|---|---|---|---|
| Rapid adoption of AI-augmented multimodal imaging platforms for small-animal studies | +0.9% | North America; Europe | Medium term (2–4 years) |
| Expansion of cell & gene therapy pipelines driving demand for longitudinal in-vivo tracking | +0.8% | Global | Long term (≥ 4 years) |
| Government-sponsored national preclinical imaging infrastructure programs | +0.6% | North America; Asia | Medium term (2–4 years) |
| Increase in preclinical research funding by both private and public organizations | +0.5% | Europe; Asia | Medium term (2–4 years) |
| Miniaturization of high-field MRI magnets enabling point-of-need rodent imaging | +0.4% | Global | Long term (≥ 4 years) |
| Integration of molecular imaging with CRISPR-based animal models | +0.3% | Global | Long term (≥ 4 years) |
| Source: Mordor Intelligence | |||
AI-Augmented Multimodal Imaging: Redefining Research Capabilities
Automated image acquisition and cross-modality analysis powered by artificial intelligence now cut processing times by as much as 70%, freeing scientists to focus on interpretation rather than data wrangling.[1]Bruker Corporation, “AI-Enhanced Multimodal Imaging for Translational Research,” bruker.com The technology enables synchronized anatomical, functional, and molecular readouts within the same animal, boosting statistical power while reducing cohort sizes. Fluorescence microscopy paired with 3T–7T MRI furthers insight into ionic shifts in cardiac and neurologic tissue, demonstrating the preclinical imaging market’s push toward non-invasive, longitudinal observation of disease progression. Commercial platforms embedding AI pipelines also simplify onboarding for less-experienced laboratories, widening the user base and injecting fresh demand into the preclinical imaging market.
Expansion of Cell & Gene Therapy Pipelines Driving Demand for Longitudinal In-vivo Tracking
Sixteen U.S. approvals for cell and gene therapies through 2024 created ripple effects that permeate discovery and toxicology workflows.[2]U.S. Food and Drug Administration, “Approved Cellular and Gene Therapy Products,” fda.gov Academic hubs such as Stanford’s Center for Cell and Gene Therapy illustrate how reporter gene imaging allows transplanted cells to be followed for months, providing safety and persistence data that regulators require.[3]Stanford Medicine, “Reporter Gene Imaging in Cell Therapy,” med.stanford.edu These needs translate to sustained orders for multimodal scanners capable of sensitive, whole-body tracking, reinforcing long-term growth in the preclinical imaging market.
Government-Sponsored National Preclinical Imaging Infrastructure Programs
Grant schemes like the U.S. Small Business Innovation Research initiative funnel up to USD 1.8 million into imaging technology development, encouraging start-ups to commercialize innovations that academic budgets alone could not support. Public funds lower the cost barrier for high-field MRI and hybrid PET/SPECT/CT platforms, deepening installed bases and stimulating service revenue across the preclinical imaging market.
Increase in Preclinical Research Funding from Private and Public Organizations
A GBP 57 (USD 76.7) million award to three U.K. universities in 2024 underscores the global surge of capital targeting advanced imaging, quantum technologies, and med-tech. Complementary micro-grants, such as the USD 5,000 MRI pilot awards issued by Stanford’s Wu Tsai Neurosciences Institute, cultivate a pipeline of novel applications that later mature into commercial demand. More institutions entering the frame multiply usage hours on shared equipment, driving consumables and maintenance revenue within the preclinical imaging market.
Restraint Impact Analysis
| Restraint | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
|---|---|---|---|
| Scarcity of skilled operators for multimodal systems in emerging markets | -0.7% | Emerging markets | Medium term (2–4 years) |
| Strict regulations in preclinical research | -0.6% | Europe; North America | Medium term (2–4 years) |
| High installation and operational costs associated with preclinical imaging modalities | -0.5% | Global | Short term (≤ 2 years) |
| Limited standardization across imaging modalities and protocols | -0.4% | Global | Medium term (2–4 years) |
| Source: Mordor Intelligence | |||
Scarcity of Skilled Operators for Multimodal Systems in Emerging Markets
Hybrid scanners demand cross-training in MRI, PET, optics, and data science, skills rarely found in a single individual. Laboratory downtime arises when qualified staff migrate to higher-paying hubs, constraining capacity expansion. Vendors respond with cloud-based remote operation dashboards that stretch expert support across facilities, yet talent shortages persist, tempering the pace of new installations in parts of Asia, Latin America, and Africa.
Strict Regulations in Preclinical Research
Revised guidance on animal welfare in the European Union mandates deeper justification for animal numbers, intensifying documentation workload and lengthening study timelines. Projects that cannot integrate advanced imaging to monitor the same animals over time now face increased scrutiny, creating a compliance hurdle for less-equipped sites and restraining pockets of demand in the preclinical imaging market.
Segment Analysis
By Modality: Hybrid Platforms Outpace Established Optical Leaders
Optical systems retained 35.32% of the preclinical imaging market in 2024, benefiting from affordability, intuitive operation, and real-time readouts that suit routine oncology and infectious-disease studies. The segment’s installed base remains pivotal for high-throughput screening, yet its CAGR lags emerging alternatives. Hybrid systems, notably PET/SPECT/CT and PET/MR, are forecast to grow 9.82% annually through 2030 as investigators seek multi-parametric insights without multiple anesthetic events. Advanced devices such as the MILABS VECTor integrate functional and anatomical imaging down to 4 µm, expanding experimental design latitude. Revvity’s IVIS SpectrumCT 2 exemplifies the convergence trend by adding CT attenuation correction to optical data, thereby enhancing quantification accuracy and boosting the preclinical imaging market size for hybrid platforms.
Falling component costs and improved workflow automation further accelerate hybrid adoption. Research consortia in Asia and Europe increasingly mandate multimodal capabilities when procuring shared equipment, highlighting the strategic shift from single-modality reliance. These preferences feed recurring demand for service contracts and software upgrades, deepening vendor revenue streams across the preclinical imaging market.
Note: Segment shares of all individual segments available upon report purchase
By Application: Oncology Leads but Neurology Surges
Oncology applications generated 40.14% of revenue in 2024, underpinned by continual innovation in immuno-oncology and targeted drug delivery. Chemical exchange saturation transfer (CEST) MRI, nanoparticle-enhanced CT, and optical reporters enable early tumor response assessment, guiding dose selection and accelerating go/no-go decisions. Meanwhile, neurology commands the fastest CAGR of 10.31% to 2030, spurred by aging populations and unmet needs in neurodegenerative disorders. High-field functional MRI paired with magnetic resonance spectroscopy allows researchers to interrogate both structure and metabolism in transgenic mouse models, an advance exemplified by Bruker’s BioSpec Maxwell series.
Cross-fertilization between neurology and cell-based therapeutics is adding further momentum. As gene-editing and regenerative therapies transition from concept to clinic, sponsors leverage longitudinal imaging to track vector biodistribution and graft viability, which expands the preclinical imaging market size tied to neurological indications.
By End User: CROs Capture Momentum from Pharmaceutical Outsourcing
Pharmaceutical and biotechnology enterprises held 45.61% of the preclinical imaging market in 2024 as they continue to anchor significant internal discovery and toxicology work. Nonetheless, CROs grow at an 11.91% CAGR because they provide turnkey multimodal capabilities, certified quality systems, and rapid study initiation. Smaller biotechs opt for external imaging to avoid capital expenditure, while large pharma uses CROs to flex capacity during peak pipelines. This outsourcing wave stimulates sales of scalable systems and cloud-ready analytics dashboards, enriching the preclinical imaging market size served by service providers.
CRO consolidation is also underway. Regional providers merge to achieve critical mass, negotiate better equipment pricing, and offer end-to-end regulatory datasets. The trend convinces equipment vendors to package maintenance and training services, helping CRO clients keep uptime high and maintain compliance without adding staff.
Note: Segment shares of all individual segments available upon report purchase
Geography Analysis
North America accounted for 48.18% of the preclinical imaging market in 2024. Federal grants like SBIR and sustained venture capital inflows finance a dense network of academic-industry collaborations. Centers such as MD Anderson Cancer Center house 7 T MRI and tri-modality PET/SPECT/CT systems, underlining the region’s commitment to maintaining technological edge. Breakthroughs such as integrated photoacoustic tomography-MRI workflows have emerged from U.S. labs, enabling concurrent vascular and metabolic imaging that refines tumor characterization.
Asia is the fastest-growing region with a 9.53% CAGR through 2030. China and Japan spearhead investment in sophisticated facilities, while national funding schemes streamline procurement approvals. Hong Kong Polytechnic University’s installation of 7 T MRI and advanced photoacoustic ultrasound reflects the region’s rapid capability build-up. Governments also nurture domestic CROs, offering subsidies that offset high import tariffs on imaging components, expanding regional participation in the preclinical imaging market.
Europe maintains robust share through well-coordinated public-private partnerships. Stringent animal welfare regulations accelerate demand for non-invasive modalities that reduce animal numbers, aligning ethical and scientific priorities. Investment vehicles like Discovery Park Ventures’ stake in Vox Imaging Technology channel fresh capital into MRI miniaturization, ensuring a pipeline of home-grown innovation. Vendors emphasize harmonized software platforms across preclinical and clinical lines: United Imaging’s translational architecture lets data flow seamlessly from rodent to human studies, reinforcing Europe’s focus on clinically predictive imaging workflows.
Competitive Landscape
The preclinical imaging market skews toward moderate concentration. Top players Bruker, Siemens Healthineers, and Revvity collectively command a sizable installed base and augment portfolios via strategic acquisitions. Bruker’s move into spatial transcriptomics illustrates diversification aimed at whole-organism molecular readouts, tightening its grip on cross-omic workflows. Siemens promotes end-to-end integration between its clinical MRI line and in-house preclinical systems, leveraging scale advantages in magnet manufacturing. Revvity packages AI-driven analytics to shorten study cycles, carving competitive differentiation beyond hardware.
Specialist firms such as Mediso and MR Solutions thrive by tailoring imaging suites for niche modalities like cryogen-free MRI or ultra-high-resolution SPECT. Their agility allows rapid customization for emerging therapeutic areas before diversified conglomerates retool. Meanwhile, cloud-native start-ups focus on data harmonization and remote scanner control, addressing operator scarcity and positioning themselves as indispensable partners to both equipment vendors and service laboratories. Regulatory acumen increasingly separates contenders: suppliers offering validated workflows aligned with FDA preclinical guidance attract pharma clients eager to streamline submission dossiers.
Preclinical Imaging Industry Leaders
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Bruker Corporation
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PerkinElmer Inc.
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FUJIFILM Holdings Corporation
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Mediso Ltd
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Siemens Healthineers AG
- *Disclaimer: Major Players sorted in no particular order
Recent Industry Developments
- April 2025: Bruker Corporation expanded its preclinical imaging portfolio with the launch of the BioSpec Maxwell series, featuring enhanced magnetic field strengths and integrated functional and metabolic imaging capabilities for neurological disease research.
- January 2025: The Centers for Medicare & Medicaid Services (CMS) launched the Cell and Gene Therapy Access Model to enhance access to cell and gene therapies, with applications open until March 14, 2025, potentially increasing demand for preclinical imaging in therapy development.
- May 2024: Shanghai United Imaging Healthcare Co., LTD received the United States Food and Drug Administration approval for the uMR Jupiter 5T MRI system. This whole-body magnetic resonance imaging system transcends the conventional limitations of ultra-high-field imaging and represents an advancement in diagnostic radiology.
- February 2024: Shanghai United Imaging Healthcare Co., LTD signed multiple partnership agreements at the Arab Health 2024 to expand its footprint in the Middle East region. The company partnered with Prepaire Labs, a pioneering biotechnology company revolutionizing drug discovery and personalized medicine. The company signed a partnership agreement with Al Mana Group, a pioneer in the healthcare field in the Kingdom of Saudi Arabia. The company also partnered strategically with the National Blood Cancer Center (NBCC), a chain of radiology centers in Saudi Arabia. This partnership covers system installations, academic cooperation, organizing seminars, and more.
Global Preclinical Imaging Market Report Scope
As per the scope of this report, preclinical imaging is the visualization technique employed on living animals for research purposes.
The preclinical imaging market is segmented by modality, application, end user, and geography. By modality, the market is segmented as optical imaging systems, nuclear imaging systems (PET/SPECT), micro-MRI, micro-CT, micro-ultrasound, photoacoustic imaging systems, hybrid & multi-modal platforms, and other modalities. By application, oncology, neurology, cardiovascular disorders, immunology & infectious diseases, metabolic disorders, and others. By end user the market is segmented into pharmaceutical & biotechnology companies, academic & research institutions, contract research organizations, and government & non-profit labs. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East & Africa, and South America. For each segment, the market sizing and forecasts have been done based on value (USD).
| Optical Imaging Systems |
| Nuclear Imaging Systems (PET/SPECT) |
| Micro-MRI |
| Micro-CT |
| Micro-Ultrasound |
| Photoacoustic Imaging Systems |
| Hybrid & Multi-modal Platforms |
| Other Modalities |
| Oncology |
| Neurology |
| Cardiovascular Disorders |
| Immunology & Infectious Diseases |
| Metabolic Disorders |
| Others |
| Pharmaceutical & Biotechnology Companies |
| Academic & Research Institutions |
| Contract Research Organizations |
| Government & Non-profit Labs |
| North America | United States |
| Canada | |
| Mexico | |
| Europe | Germany |
| United Kingdom | |
| France | |
| Italy | |
| Spain | |
| Rest of Europe | |
| Asia-Pacific | China |
| Japan | |
| India | |
| Australia | |
| South Korea | |
| Rest of Asia-Pacific | |
| Middle East & Africa | GCC |
| South Africa | |
| Rest of Middle East & Africa | |
| South America | Brazil |
| Argentina | |
| Rest of South America |
| By Modality | Optical Imaging Systems | |
| Nuclear Imaging Systems (PET/SPECT) | ||
| Micro-MRI | ||
| Micro-CT | ||
| Micro-Ultrasound | ||
| Photoacoustic Imaging Systems | ||
| Hybrid & Multi-modal Platforms | ||
| Other Modalities | ||
| By Application | Oncology | |
| Neurology | ||
| Cardiovascular Disorders | ||
| Immunology & Infectious Diseases | ||
| Metabolic Disorders | ||
| Others | ||
| By End User | Pharmaceutical & Biotechnology Companies | |
| Academic & Research Institutions | ||
| Contract Research Organizations | ||
| Government & Non-profit Labs | ||
| By Geography | North America | United States |
| Canada | ||
| Mexico | ||
| Europe | Germany | |
| United Kingdom | ||
| France | ||
| Italy | ||
| Spain | ||
| Rest of Europe | ||
| Asia-Pacific | China | |
| Japan | ||
| India | ||
| Australia | ||
| South Korea | ||
| Rest of Asia-Pacific | ||
| Middle East & Africa | GCC | |
| South Africa | ||
| Rest of Middle East & Africa | ||
| South America | Brazil | |
| Argentina | ||
| Rest of South America | ||
Key Questions Answered in the Report
What is the current size of the preclinical imaging market?
The preclinical imaging market size stands at USD 4.46 billion in 2025.
Which modality is growing fastest?
Hybrid and multimodal platforms are expanding at a 9.82% CAGR between 2025 and 2030.
Why are CROs gaining share?
Pharmaceutical firms outsource imaging to CROs to access specialized equipment and regulatory expertise, driving an 11.91% CAGR for CRO revenue.
Which region is expected to show the highest growth?
Asia Pacific is forecast to register a 9.53% CAGR through 2030 due to expanding research infrastructure and rising R&D budgets.
How is AI influencing preclinical imaging?
AI reduces image-processing time by up to 70% and enables cross-modality biomarker discovery, improving study speed and reproducibility.
What financial barriers limit wider adoption?
High-field MRI systems can exceed USD 1 million with annual service contracts up to USD 114,000, prompting many small institutes to rely on shared imaging centers.
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