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The market is segmented by Cytokine Type, Therapeutic Application (Cancer, Asthma and Airway Inflammation, Arthritis, and Other Therapeutic Applications), and Geography.
Fastest Growing Market:
Cytokines are molecular messengers that allow the cells of the immune system to communicate with one another, to generate a coordinated, robust, but self-limited response to a target antigen. There are two types of cytokines used to treat patients with cancer, namely, interferons (INFs) and interleukins (ILs). A third type, called hematopoietic growth factors, is used to counteract some of the side effects of certain chemotherapy regimen. The growing interest, over the past two decades, in harnessing the immune system to eradicate cancer has been accompanied by heightened efforts to characterize cytokines and exploit their vast signaling networks, to develop cancer treatments. They directly stimulate immune effector cells and stromal cells at the tumor site, and enhance tumor cell recognition by cytotoxic effector cells. Numerous animal tumor model studies have demonstrated that cytokines have broad anti-tumor activity, which has been translated into a number of cytokine-based approaches for cancer therapy. Cytokines have proven to be effective in the treatment of cancer, and may continue to play a major role in the development of cancer immunotherapy. Cytokines are finding increasing acceptance in cancer therapy over the world.
As per the scope of the report, cytokines are produced by a broad range of cells, including cells of immune system of the human body, with respect to complex immune response. Cytokines help in intercellular communication in immune response, as they are cell signaling molecules, and thus, trigger the movement of cells on inflammation, infection site.
|By Cytokine Type|
|Tumor Necrosis Factor-TNF|
|Epidermal Growth Factor-EGF|
|Other Cytokine Types|
|By Therapeutic Application|
|Asthma and Airway Inflammation|
|Other Therapeutic Applications|
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The other applications segment includes diseases, like multiple sclerosis, psoriasis, ankylosing spondylitis, and inflammatory bowel disease. The inhibition of TNF using various blocking mediators has proven to be an effective therapy for patients with various forms of inflammatory disease, including psoriasis, psoriatic arthritis, ankylosing spondylitis, and inflammatory bowel disease. High TNF levels play a significant role in the raised, red skin plaques that come with psoriasis.
Cytokines are important in the pathogenesis of IBD, and their manipulation has successfully reduced disease severity and maintained remission. The approval of IL-17A-blocking biologics for the treatment of moderate-to-severe plaque psoriasis is a positive indicator for the market development,. However, further studies are being conducted to improve the efficacy of these treatments.
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North America is dominating the cytokine market, due to the rising prevalence of cancer in the region. Numerous animal tumour model studies have demonstrated that cytokines have broad anti-tumour activity, which has been translated into a number of cytokine-based approaches for cancer therapy. As per the Cancer Statistics, in 2016, an estimated 1.6 million new cases of cancer were diagnosed in the United States, with prevalence expected to rise to almost 19 million by 2024. Augmenting growth in the R&D of cancer therapy, along with lesser side effects (as compared to chemotherapy), has predisposed cytokine therapy, which is a non-specific immunotherapy. This factor has increased the market share of cytokines among cancer therapies, in the United States.
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The cytokine market consists of several major players. The comapanies are implementing certain strategic initiatives, such as a mergers, new product launches, acquisitions, and partnerships, which help them in strengthening their market position. For instance, in October 2017, US FDA approved Stelara (ustekinumab) for the treatment of adolescents with moderate-to-severe plaque psoriasis, which is developed by Janssen Pharmaceutica.
1.1 Study Deliverables
1.2 Study Assumptions
1.3 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Increased Acceptance in Cancer Therapy
4.2.2 Potential Biomarker for Neonatal Sepsis
4.2.3 Potential Contribution in Stem Cell Therapy
4.3 Market Restraints
4.3.1 Extensive Investments
4.3.2 Lacks Specificity
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION
5.1 By Cytokine Type
5.1.1 Tumor Necrosis Factor-TNF
5.1.4 Epidermal Growth Factor-EGF
5.1.5 Other Cytokine Types
5.2 By Therapeutic Application
5.2.2 Asthma and Airway Inflammation
5.2.4 Other Therapeutic Applications
5.3.1 North America
126.96.36.199 United States
188.8.131.52 United Kingdom
184.108.40.206 Rest of Europe
220.127.116.11 South Korea
18.104.22.168 Rest of Asia-Pacific
5.3.4 Middle East & Africa
22.214.171.124 South Africa
126.96.36.199 Rest of Middle East & Africa
5.3.5 South America
188.8.131.52 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.6 Bayer Healthcare Pharmaceuticals
6.1.7 Thermo Fisher Scientific
6.1.11 Johnson & Johnson
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
** Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments