Cold Chain Packaging Market Size and Share
Market Overview
| Study Period | 2019 - 2030 |
|---|---|
| Market Size (2025) | USD 32.29 Billion |
| Market Size (2030) | USD 48.93 Billion |
| Growth Rate (2025 - 2030) | 8.67% CAGR |
| Fastest Growing Market | Asia Pacific |
| Largest Market | Europe |
| Market Concentration | Medium |
Major Players
*Disclaimer: Major Players sorted in no particular order Image © Mordor Intelligence. Reuse requires attribution under CC BY 4.0. |
|
Cold Chain Packaging Market Analysis by Mordor Intelligence
The cold chain packaging market size stands at USD 32.29 billion in 2025 and is projected to reach USD 48.93 billion by 2030, expanding at an 8.67% CAGR. Growth is underpinned by rising biologics volumes, expanding e-commerce grocery fulfilment, and global vaccine initiatives that standardize temperature-controlled distribution. Regulatory frameworks such as the United States Food and Drug Administration’s 21 CFR 600.15 and the European Union’s new Packaging and Packaging Waste Regulation compel validated solutions, while real-time IoT monitoring elevates performance expectations. Consolidation among logistics majors amplifies technology diffusion, and corporate ESG targets accelerate the pivot toward reusable and bio-based formats, reshaping supplier strategies across the cold chain packaging market.
Key Report Takeaways
- By product, insulated containers led with 35.53% revenue share in 2024; temperature-monitoring devices are forecast to grow at a 12.95% CAGR to 2030.
- By packaging system, passive solutions held 55.32% of the cold chain packaging market share in 2024, while hybrid systems record the highest projected CAGR at 10.32% through 2030.
- By material, expanded polystyrene accounted for 40.43% share of the cold chain packaging market size in 2024; bio-based phase change materials are advancing at an 11.23% CAGR through 2030
- By usability, single-use formats commanded 70.34% share in 2024, whereas reusable solutions are projected to expand at 9.43% CAGR to 2030.
- By application, pharmaceuticals and biotechnology captured 45.22% of the cold chain packaging market in 2024; clinical trials and diagnostics are expected to grow at 11.34% CAGR by 2030.
- By geography, Europe led with 38.96% share in 2024, while Asia-Pacific is set to expand at 12.02% CAGR through 2030.
Global Cold Chain Packaging Market Trends and Insights
Drivers Impact Analysis
| Driver | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
|---|---|---|---|
| Biologics and cell-/gene-therapy logistics | +1.8% | North America & Europe | Medium term (2-4 years) |
| E-commerce grocery and meal-kit expansion | +1.5% | Asia-Pacific and North America | Short term (≤ 2 years) |
| Global vaccine programmes | +1.2% | Asia-Pacific, Middle East & Africa, Latin America | Medium term (2-4 years) |
| Decentralized clinical-trial parcels | +0.9% | North America, Europe, expanding Asia-Pacific | Long term (≥ 4 years) |
| Reusable passive shippers for ESG compliance | +0.7% | Europe and North America | Long term (≥ 4 years) |
| Insurer-driven smart indicator uptake | +0.6% | Developed markets worldwide | Medium term (2-4 years) |
| Source: Mordor Intelligence | |||
Boom in Biologics and Cell-/Gene-Therapy Logistics
Nearly half of new pharmaceuticals require temperature control, and many advanced therapies need cryogenic conditions below -150 °C. In January 2025 Cryoport introduced the HV3 shipper that maintains such ultra-low levels for prolonged periods, illustrating the sector’s shift toward specialised designs. [1]Cryoport, “Cryoport Unveils HV3 Cryogenic Shipping System for Advanced Therapies,” gasworld.com The FDA’s biologics licensing requirements demand validated evidence of stability throughout transit, making packaging qualification integral to product approval.[2]U.S. Food and Drug Administration, “Biologics License Applications and Master Files,” federalregister.gov Personalised medicine trends intensify shipment frequency and value, driving premium demand across the cold chain packaging market.
Expansion of E-commerce Grocery and Meal-Kit Delivery
Online grocery volumes for chilled and frozen foods increase the need for lightweight, space-efficient insulation that withstands last-mile variability. HelloFresh employs AI to adjust pack configuration to weather and route specifics, demonstrating how data drives material selection. Ranpak’s curbside-recyclable climaliner Plus, launched April 2024, offers 72 hours of thermal protection and responds to consumers’ sustainability expectations. These innovations expand the cold chain packaging market beyond traditional pharmaceutical lanes.
Global Vaccine Initiatives in Emerging Nations
Gavi, UNICEF and WHO establish procurement frameworks that set global performance baselines. Ethiopia’s 2024 solar electrification of 300 clinics underscores infrastructure constraints that packaging must overcome. Freeze-preventive cold boxes endorsed by WHO eliminate ice-pack conditioning and reduce wastage in rural deployments. Such programmes push suppliers toward rugged, rapidly deployable designs, sustaining demand across the cold chain packaging market.
Decentralized Clinical-Trial Parcel Demand
Regulatory support for direct-to-patient models increases shipment counts while shrinking payloads. Digital display labelling, recognised by ISPE in 2025, allows real-time multilingual updates without relabelling. [3]ISPE, “Digital Display Labelling in Clinical Supplies,” ispe.org Packaging must protect sensitive samples under varied domestic storage conditions, favouring extended-duration passive systems equipped with smart sensors. Drone-compatible formats are also gaining traction, enhancing service reach for remote participants.
Restraints Impact Analysis
| Restraint | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
|---|---|---|---|
| Polymer feedstock price volatility | -1.4% | Global, pronounced Asia-Pacific | Short term (≤ 2 years) |
| EU circular-economy limits on EPS | -0.8% | European Union | Medium term (2-4 years) |
| Air-freight capacity squeeze for bulky shippers | -0.6% | Global air-cargo hubs | Short term (≤ 2 years) |
| Lithium battery limits on active systems | -0.4% | Worldwide air transport routes | Medium term (2-4 years) |
| Source: Mordor Intelligence | |||
Polymer Feedstock Price Volatility
Upward swings in polyethylene and polypropylene costs compress converter margins and can delay switching to reusable packaging that carries higher upfront spend. Smaller producers often lack hedging mechanisms, prompting them to rationalise portfolios and prioritise high-value pharmaceutical accounts.
EU Circular-Economy Limits on EPS
The Packaging and Packaging Waste Regulation effective February 2025 obliges full recyclability by 2030. Makers accelerate alternative developments; DS Smith’s TailorTemp fibre solution, launched January 2025, keeps goods cool for 36 hours while fitting curbside recycling streams DS Smith. Mandatory extended-producer responsibility fees raise compliance costs, nudging the cold chain packaging market toward bio-based materials.
Segment Analysis
By Product: Smart Monitoring Drives Innovation
Insulated containers provided the backbone of shipments and accounted for 35.53% of the cold chain packaging market in 2024. Despite this dominance, temperature-monitoring devices post a 12.95% CAGR as supply chains demand continuous visibility. Smart labels such as Timestrip’s semaglutide indicator extend compliance to high-value biologics, capturing adoption across healthcare providers.
The convergence of IoT chips and low-power networks upgrades passive boxes into connected assets. SkyCell’s 1500X hybrid container runs for 270 hours and transmits live data, illustrating how monitoring devices integrate with insulation substrates to limit excursions. These advances attract insurers that now reward proven risk reduction, expanding addressable volumes for device makers within the cold chain packaging market.
Note: Segment shares of all individual segments available upon report purchase
By Packaging System: Hybrid Solutions Gain Momentum
Passive shippers retained 55.32% share of the cold chain packaging market size in 2024, valued for simplicity and regulatory familiarity. Hybrid formats, however, post the fastest 10.32% CAGR by embedding sensors and limited power assistance inside traditional shells, thereby balancing cost and control. Va-Q-Tec’s Thermal Coat adds an intelligent layer to legacy boxes and reduces reliance on fully powered units.
Global airlines tighten lithium-battery carriage rules, capping state-of-charge at 30%, which constrains active container usage. Solar harvesting and supercapacitor integration mitigate this hurdle and push manufacturers toward passive-active hybrids. As compliance audits intensify, shippers with built-in traceability gain procurement preference, strengthening hybrid growth across the cold chain packaging market.
By Material: Bio-Based PCMs Lead Sustainability Shift
Expanded polystyrene dominated 40.43% of the cold chain packaging market share in 2024 owing to cost efficiency. Regulatory scrutiny, however, elevates demand for bio-based phase change materials, which grow at 11.23% CAGR. MDPI research in 2025 showed microencapsulated PCMs delivering 144.3 kJ/kg latent heat, meeting 2 °C to 8 °C pharma requirements while enabling recycling.
Vacuum panels and phenolic foams serve premium niches seeking thinner walls and extended duration. Cellulose sponge cooling media, documented by peer-reviewed studies, add antimicrobial benefits and biodegradability, aligning with EU circular goals. Material diversification therefore accelerates, migrating the cold chain packaging market toward circularity without compromising performance.
By Usability: Reusable Systems Gain ESG Traction
Single-use designs still occupied 70.34% of shipments in 2024 due to contamination control and logistical ease. Corporate sustainability pledges now favour loops: Cold Chain Technologies targets elimination of 100 million lb of landfill waste by 2025 through reusable fleets, reporting 60% fossil-fuel savings on mature lanes.
Asset-tracking via IoT reduces loss rates and maximises turns, shortening payback to fewer than eight trips for high-frequency routes. Rental models such as Sonoco’s Orion r® service shift capex to opex, widening adoption among mid-sized pharma exporters. These incentives underpin the 9.43% CAGR for reusable formats across the cold chain packaging market.
By Application: Clinical Trials Propel Specialized Demand
Pharmaceuticals and biotechnology represented 45.22% of revenue in 2024, driven by strict 2 °C to 8 °C and -20 °C protocols. Decentralized clinical trials lift demand for small, patient-direct cartons and drive an 11.34% CAGR in the segment. ISPE-recognised digital labelling eliminates manual over-stickering, cutting errors and meeting multilingual rules.
Food applications remain volume heavy, especially dairy and frozen desserts that require moderate hold times. Cross-pollination of pharma-grade indicators into premium seafood shipping raises quality benchmarks. Chemical and industrial flows use cryo-friendly drums for specialty resins, adding incremental demand to the cold chain packaging market.
Segment Analysis: By End-User Application
Geography Analysis
Europe’s 38.96% share in 2024 reflects mature pharmaceutical clusters, advanced infrastructure, and regulatory emphasis on carbon reduction. The European Medicines Agency updated guidance in 2025, prompting wider validation of reusable systems. Va-Q-Tec’s German facilities anchor regional innovation, while new Dutch production from Cold Chain Technologies shortens lead times for life-science clients.
Asia-Pacific records the highest 12.02% CAGR to 2030, fuelled by pharmaceutical capacity expansions in India and rising biologics output in South Korea. Government vaccine programmes mobilise refrigerated logistics, and local suppliers partner with Cryoport’s new United Kingdom hub to replicate best practice regionwide. As infrastructure scales, regional players increasingly specify hybrid containers to navigate variable power networks, strengthening the cold chain packaging market in the region.
North America continues to invest in serialisation and traceability under the Drug Supply Chain Security Act, reinforcing demand for smart shippers. Cross-border trade with Mexico sustains temperature-controlled produce flows, while Canada’s biologics firms pilot bio-based PCMs. Middle East and Africa benefit from Gavi-backed solar-powered storage that lifts vaccine coverage, and Latin America improves seafood exports through insulated pallet covers. This diverse landscape ensures the cold chain packaging market remains geographically balanced with Asia-Pacific supplying the lion’s share of incremental growth.
Competitive Landscape
The cold chain packaging market is moderately fragmented yet consolidating. Global integrators pursue scale and technology depth; DHL’s March 2025 acquisition of CRYOPDP added 600,000 annual life-science shipments and widened reach in Asia-Pacific and EMEA. TOPPAN’s USD 1.8 billion purchase of Sonoco’s Thermoformed and Flexible Packaging unit broadened its sustainable material suite.
Incumbents such as Sonoco ThermoSafe, Pelican BioThermal, and Va-Q-Tec defend share through patent portfolios in vacuum insulation and hybrid monitoring. Emerging tech suppliers like Wiliot embed postage-stamp-sized sensors that broadcast via Bluetooth, turning every box into a data node. Strategic alliances flourish; Envirotainer’s 2024 pact with a leading airline promotes sustainable aviation fuel usage within temperature-controlled lanes.
Competition now hinges on aligning performance with recyclability. DS Smith’s fibre-based TailorTemp, Ranpak’s paper-based thermal liners, and SkyCell’s long-run hybrid containers differentiate on verified carbon savings. Suppliers failing to invest in circular-ready platforms risk exclusion from pharmaceutical vendor lists, sharpening innovation cycles across the cold chain packaging market.
Cold Chain Packaging Industry Leaders
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Cold chain Technologies
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Cryopak
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Sonoco Thermosafe
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Sofrigam Company
-
Softbox Systems Ltd
- *Disclaimer: Major Players sorted in no particular order
Recent Industry Developments
- January 2025: Cryoport unveiled the HV3 cryogenic shipper for advanced therapies, offering enhanced ultra-low temperature hold times.
- January 2025: DS Smith launched TailorTemp at PharmaPack Europe, a fully recyclable fibre solution delivering 36-hour cooling.
- December 2024: Sonoco finished the USD 4.2 billion purchase of Eviosys, expanding its metal packaging platform
- June 2024: Cold Chain Technologies opened a manufacturing and distribution centre in Breda, Netherlands, enhancing European supply capacity.
Global Cold Chain Packaging Market Report Scope
A cold chain product is defined as any temperature-sensitive product, such as frozen foods, research samples, or pharmaceuticals. Cold chain packaging, is vital for maintaining the thermal integrity of temperature-sensitive products during transport. Cold chain packaging can use active or passive packaging methods.
Active packaging configurations are usually leased containers that employ a power source, batteries or electricity, and a thermostat to control heating or cooling within the shipping container.
Passive packaging configurations are manufactured containers that utilize insulated packaging such as polystyrene, polyurethane, or vacuum insulated panels and phase change materials (PCM) to maintain a desired temperature inside the shipping container.
| Insulated Containers |
| Insulated Shippers |
| Refrigerants Gel Packs and PCMs |
| Temperature-Monitoring Devices |
| Vacuum-Insulated Panels |
| Dry-Ice Systems |
| Active Systems |
| Passive Systems |
| Hybrid Systems |
| Expanded Polystyrene (EPS) |
| Polyurethane (PUR) |
| Vacuum Insulation Panels (VIP) |
| Expanded Polypropylene (EPP) |
| Bio-based PCMs |
| Corrugated Cardboard with Barrier Liners |
| High-performance Foams (Phenolic, PIR) |
| Single-use |
| Reusable |
| Pharmaceuticals and Biotechnology |
| Clinical Trials and Diagnostics |
| Dairy and Frozen Desserts |
| Meat and Seafood |
| Other Application |
| North America | United States | |
| Canada | ||
| Mexico | ||
| Europe | Germany | |
| United Kingdom | ||
| France | ||
| Italy | ||
| Spain | ||
| Russia | ||
| Rest of Europe | ||
| Asia-Pacific | China | |
| India | ||
| Japan | ||
| South Korea | ||
| Australia and New Zealand | ||
| Rest of Asia-Pacific | ||
| Middle East and Africa | Middle East | United Arab Emirates |
| Saudi Arabia | ||
| Turkey | ||
| Rest of Middle East | ||
| Africa | South Africa | |
| Nigeria | ||
| Egypt | ||
| Rest of Africa | ||
| South America | Brazil | |
| Argentina | ||
| Rest of South America | ||
| By Product | Insulated Containers | ||
| Insulated Shippers | |||
| Refrigerants Gel Packs and PCMs | |||
| Temperature-Monitoring Devices | |||
| Vacuum-Insulated Panels | |||
| Dry-Ice Systems | |||
| By Packaging System | Active Systems | ||
| Passive Systems | |||
| Hybrid Systems | |||
| By Material | Expanded Polystyrene (EPS) | ||
| Polyurethane (PUR) | |||
| Vacuum Insulation Panels (VIP) | |||
| Expanded Polypropylene (EPP) | |||
| Bio-based PCMs | |||
| Corrugated Cardboard with Barrier Liners | |||
| High-performance Foams (Phenolic, PIR) | |||
| By Usability | Single-use | ||
| Reusable | |||
| By Application | Pharmaceuticals and Biotechnology | ||
| Clinical Trials and Diagnostics | |||
| Dairy and Frozen Desserts | |||
| Meat and Seafood | |||
| Other Application | |||
| By Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Russia | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| India | |||
| Japan | |||
| South Korea | |||
| Australia and New Zealand | |||
| Rest of Asia-Pacific | |||
| Middle East and Africa | Middle East | United Arab Emirates | |
| Saudi Arabia | |||
| Turkey | |||
| Rest of Middle East | |||
| Africa | South Africa | ||
| Nigeria | |||
| Egypt | |||
| Rest of Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
Key Questions Answered in the Report
What is the current cold chain packaging market size and expected growth?
The market stands at USD 32.29 billion in 2025 and is projected to reach USD 48.93 billion by 2030, reflecting an 8.67% CAGR.
Which segment is growing fastest within the cold chain packaging market?
Temperature-monitoring devices lead with a 12.95% CAGR as supply chains prioritise real-time visibility.
How do sustainability regulations influence material choices?
The EU requirement for full recyclability by 2030 accelerates shifts from EPS to bio-based PCMs and fibre-based insulation solutions.
Why are hybrid packaging systems gaining traction?
Hybrid shippers merge passive insulation with smart sensors, balancing cost with regulatory compliance, and are expanding at 10.32% CAGR.
What drives Asia-Pacific’s rapid cold chain packaging market growth?
Pharmaceutical manufacturing expansion, vaccine logistics, and modernising refrigeration infrastructure push the region to a 12.02% CAGR.
How are reusable packaging formats affecting total cost of ownership?
IoT-enabled tracking and rental models reduce loss and capital expenditure, cutting payback periods to fewer than eight shipping cycles for high-frequency lanes.
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