Cancer Vaccines Market - Growth, Trends, COVID-19 Impact, and Forecasts (2021 - 2026)

The Cancer Vaccines Market is Segmented by Technology (Recombinant Cancer Vaccines, Whole-cell Cancer Vaccines, DNA Cancer Vaccines, and Other Technologies), Treatment Method (Preventive Vaccine and Therapeutic Vaccine), Application (Prostate Cancer, Cervical Cancer, and Other Applications), and Geography (North America, Europe, Asia Pacific, Middle-East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Market Snapshot

Cancer Vaccines Market Bar Graph
Study Period: 2018 - 2026
Base Year: 2020
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 13.2 %

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Market Overview

The cancer vaccines market is projected to register a CAGR of 13.24% during the forecast period, with a revenue of approximately USD 4,825.61 million in 2020 and expected to reach USD 10,175.41 million by 2026.

Due to the sudden outbreak of the COVID-19, the cancer vaccine market observed a significant setback in terms of growth. As the COVID-19 cases were rising, globally the healthcare systems shifted their focus in curbing the disease, thereby, resulting in the delay of prevention, diagnosis, and treatment of other chronic conditions, like cancer. Thus, a negative impact is expected on the cancer vaccine market currently. However, in the forthcoming years, the market is expected to gain momentum due to the relaxation of restrictions and bouncing back of the R&D activities and clinical trials related to cancer vaccines.

Certain factors driving the cancer vaccine market growth include the increasing number of cancer cases, rising investments and government funding in developing cancer vaccines, and technological developments in cancer vaccines.

As per the International Agency for Research on Cancer (IARC), in December 2020, globally, 1 in 5 people develop cancer during their lifetime, and 1 in 8 men, and 1 in 11 women die from the disease. The IARC estimated that in 2020, the prevalence of cancer rose to 19.3 million cases and 10 million cancer deaths in 2020, which was around 18 million cancer cases around the world in 2018. With this growing burden, the prevention of cancer is one of the most significant challenges. Cancer vaccines play a vital role in the maintenance of the immune system, as they are considered to be biological response modifiers. These cancer vaccines target the infectious agents that may cause cancer through the production of antibodies.

Cancer vaccines are considered a new therapy and are not popular, as compared to the other alternative therapeutic drugs. However, cancer vaccines have shown great potential in both preventive and therapeutic ways. Moreover, as the number of cancer cases is increasing, the development of new cancer vaccines is also increasing for the treatment and prevention of disease. In 2019, Sanofi invested EUR 80 million in BioNTech, a German biotech company, for the development of a messenger RNA cancer vaccine for the treatment of solid tumors.

However, the stringent regulatory issues, along with longer timelines in manufacturing vaccines and the availability of alternative therapies, act as major hindering factors in the global cancer vaccines market’s growth.

Scope of the Report

As per the scope of the report, cancer vaccines are defined as the vaccines developed to prevent or treat existing cancers by strengthening the body’s natural immune response system against cancer. These cancer vaccines belong to a class of substances known as biological response modifiers. These modifiers work by stimulating or restoring the immune system’s ability to fight against diseases. The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The cancer vaccines market is segmented based on technology (recombinant cancer vaccines, whole-cell cancer vaccines, DNA cancer vaccines, and other technologies), treatment method (preventive vaccine and therapeutic vaccine), application (prostate cancer, cervical cancer, and other applications), and geography (North America, Europe, Asia Pacific, Middle-East and Africa, and South America). The report offers the value (in USD million) for the above segments.

By Technology
Recombinant Cancer Vaccines
Whole-cell Cancer Vaccines
Viral Vector and DNA Cancer Vaccines
Other Technologies (Dendritic Cells, Antigen, etc.)
By Treatment Method
Preventive Vaccine
Therapeutic Vaccine
By Application
Prostate Cancer
Cervical Cancer
Other Applications
By Geography
North America
United States
United Kingdom
Rest of Europe
Asia Pacific
South Korea
Rest of Asia Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Key Market Trends

Recombinant Cancer Vaccines are Expected to a Hold Significant Market Share in the Cancer Vaccines Market

A recombinant vaccine is a vaccine produced through recombinant DNA technology. This includes DNA encoding an antigen, which stimulates an immune response into mammalian cells, expressing the antigen in these cells and then purifying it from them. Many different viruses have been genetically modified to express tumor-associated antigens (TAA) for intramuscular or subcutaneous injection.

Poxviruses have several beneficial features as vectors for cancer vaccines, including broad cell tropism, potent immunogenicity, and pre-existing neutralizing immunity, only in those patients who received the vaccinia virus (the smallpox vaccine). Vaccinia virus, fowlpox virus, and canarypox virus have been investigated clinically for cancer vaccination.

Furthermore, numerous studies are being conducted in the field of viral recombinant cancer vaccines, which may reap positive results in the future, primarily related to cancer vaccination. This is expected to aid the market’s growth. For instance, In July 2019, Oxford Vacmedix UK Limited (OVM), a UK-based biopharma company, collaborated and issued Innovate UK grant to CHAIN Biotechnology Ltd and the University of Oxford to develop OVM-100, a recombinant overlapping peptide (ROP) HPV vaccine targeted at cervical cancer.

However, the recent COVID-19 pandemic has posed a significant negative impact on the respective segment by delaying the development activities of recombinant cancer vaccines.

Cancer Vaccines Market Key Trends

North America Dominates the Market Over the Forecast Period

North America is expected to grow due to the high prevalence of cancer and developed healthcare infrastructure in the region. The United States has a better healthcare infrastructure than most developed countries. The National Cancer Institute (NCI) stated that the national spending on cancer care is expected to reach USD 156 billion by 2020.

According to the estimates of the GLOBOCAN, in 2020, an estimated 1,95,499 new cases of cancer were diagnosed in Mexico, and 90,222 people died from the disease. The rising number of cancer cases is creating opportunities for market players.

The major market players are focusing on R&D activities to bring new and reliable treatments to the market. In December 2020, Anixa Biosciences, a San Jose, California-based biotech company with Cleveland Clinic, received USFDA investigational new drug application for its new breast cancer vaccine technology developed by Cleveland Clinic immunologist Dr. Vincent Tuohy and his research team to start the first human clinical trials.

Providence Therapeutics is a Toronto-based clinical-stage biotechnology company that develops cancer vaccines for human use. Currently, the company is developing a personalized mRNA cancer vaccine designed to generate strong T cell responses that aim to kill cancer cells and destroy tumors in ovarian cancer, breast cancer, and brain cancer.

Cancer Vaccines Market Growth Rate By Region

Competitive Landscape

The global cancer vaccines market is consolidated and consists of a few major players. Market players are adopting different growth strategies to enhance their market presence, such as partnerships, agreements, collaborations, mergers, and acquisitions. Companies, like AstraZeneca PLC, Bristol-Myers Squibb, GlaxoSmithKline, Roche, Merck & Co. Inc., OSE Immunotherapeutics, Sanofi, and Moderna, among others, hold substantial shares in the cancer vaccines market.

Recent Developments

  • In March 2021: eTheRNA, a Belgian-based immunotherapy company, received a EUR 6.9 million grant from the European Commission to accelerate the clinical development of mRNA-based vaccines for cervical cancers.
  • In November 2020: Moderna Inc. release interim data from the expansion cohort of its ongoing Phase 1 study of its mRNA personalized cancer vaccine (PCV) mRNA-4157 in combination with Merck’s Keytruda, and results demonstrated that the vaccine candidate is well tolerated at all dose levels and produced responses as measured by tumor shrinkage in HPV (-)Head and Neck Squamous Cell Carcinoma (HNSCC) patients.

Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Burden of Cancer

      2. 4.2.2 Rising Investments and Government Funding in the Development of Cancer Vaccines

      3. 4.2.3 Technological Developments in Cancer Vaccines

    3. 4.3 Market Restraints

      1. 4.3.1 Stringent Regulatory Guidelines and Longer Timelines Required for Manufacturing Process

      2. 4.3.2 Presence of Alternative Therapies

    4. 4.4 Industry Attractiveness - Porter's Five Forces Analysis

      1. 4.4.1 Bargaining Power of Buyers/Consumers

      2. 4.4.2 Bargaining Power of Suppliers

      3. 4.4.3 Threat of New Entrants

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Technology

      1. 5.1.1 Recombinant Cancer Vaccines

      2. 5.1.2 Whole-cell Cancer Vaccines

      3. 5.1.3 Viral Vector and DNA Cancer Vaccines

      4. 5.1.4 Other Technologies (Dendritic Cells, Antigen, etc.)

    2. 5.2 By Treatment Method

      1. 5.2.1 Preventive Vaccine

      2. 5.2.2 Therapeutic Vaccine

    3. 5.3 By Application

      1. 5.3.1 Prostate Cancer

      2. 5.3.2 Cervical Cancer

      3. 5.3.3 Other Applications

    4. 5.4 By Geography

      1. 5.4.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.4.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.4.3 Asia Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia Pacific

      4. 5.4.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.4.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Anixa Biosciences Inc.

      2. 6.1.2 AstraZeneca PLC

      3. 6.1.3 Bristol Myers Squibb Company

      4. 6.1.4 F Hoffmann-La Roche AG (Genentech)

      5. 6.1.5 GlaxoSmithKline PLC

      6. 6.1.6 Merck & Co. Inc.

      7. 6.1.7 OSE Immunotherapeutics

      8. 6.1.8 Sanofi SA

      9. 6.1.9 Dendreon Pharmaceuticals LLC

      10. 6.1.10 Moderna Inc.

      11. 6.1.11 Vaccitech Limited

      12. 6.1.12 ProvidenceTherapeutics

      13. 6.1.13 eTheRNA immunotherapies

    2. *List Not Exhaustive

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The Global Cancer Vaccines Market market is studied from 2018 - 2026.

The Global Cancer Vaccines Market is growing at a CAGR of 13.2% over the next 5 years.

The Global Cancer Vaccines Market is valued at 4825 Million USD in 2018.

The Global Cancer Vaccines Market is valued at 10175 Million USD in 2026.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

OSE Immunotherapeutics, GlaxoSmithKline PLC, F Hoffmann-La Roche AG (Genentech), Moderna Inc., Merck & Co. Inc. are the major companies operating in Global Cancer Vaccines Market.

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