2018 - 2026
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The cancer vaccines market is projected to register a CAGR of 13.24% during the forecast period, with a revenue of approximately USD 4,825.61 million in 2020 and expected to reach USD 10,175.41 million by 2026.
Due to the sudden outbreak of the COVID-19, the cancer vaccine market observed a significant setback in terms of growth. As the COVID-19 cases were rising, globally the healthcare systems had shifted their focus in curbing the disease thereby resulting in the delay of prevention, diagnosis, and treatment of other chronic conditions like cancer. Thus, a negative impact is expected on the cancer vaccine market currently. However, in the forthcoming years, the market is expected to gain its momentum owing to the relaxation of restrictions and bouncing back of the R&D activities and clinical trials related to cancer vaccines.
Certain factors that are driving the Cancer vaccine market's growth include the increasing number of cancer cases, rising investments and government funding in the development of cancer vaccines, and technological developments in cancer vaccines.
As per the International Agency for Research on Cancer (IARC), in December 2020, globally, 1 in 5 people develop cancer during their lifetime, and 1 in 8 men and 1 in 11 women die from the disease. The IARC estimated that in 2020, the prevalence of cancer rose to 19.3 million cases and 10 million cancer deaths in year 2020, which was around 18 million cancer cases around the world in 2018. With this growing burden, the prevention of cancer is one of the most significant challenges. The cancer vaccines play a vital role in the maintenance of the immune system, as they are considered to be biological response modifiers. These cancer vaccines target the infectious agents that may cause cancer, through the production of the antibodies.
Cancer vaccines are considered to be a new therapy and are not popular, as compared to the other alternative therapeutic drugs. However, cancer vaccines have shown great potential in both preventive and therapeutic ways. Moreover, As number of cases of cancer are increasing, the development of new cancer vaccines is also increasing for treatment and prevention of disease. In 2019, Sanofi invested EUR 80 million in BioNTech, a German biotech company, for the development of messenger RNA cancer vaccine for the treatment of solid tumors.
However,the stringent regulatory issues, along with longer timelines in manufacturing of vaccines along with the availability alternative therapies, act as major hindering factors, in terms of the global cancer vaccines market’s growth.
Scope of the Report
As per the scope of the report, cancer vaccines are defined as the vaccines developed to prevent or treat existing cancers, by strengthening the body’s natural immune response system against cancer. These cancer vaccines belong to a class of substances, known as biological response modifiers. These modifiers work by stimulating or restoring the immune system’s ability to fight against diseases. The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The cancer vaccines market is segmented on the basis of technology (recombinant cancer vaccines, whole-cell cancer vaccines, dna cancer vaccines, and other technologies), treatment method (preventive vaccine and therapeutic vaccine), application (prostate cancer, cervical cancer, and other applications), and geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report offers the value (in USD million) for the above segments.
|Recombinant Cancer Vaccines|
|Whole-cell Cancer Vaccines|
|Viral Vector and DNA Cancer Vaccines|
|Other Technologies (Dendritic Cells, Antigen, etc.)|
|By Treatment Method|
Key Market Trends
Recombinant Cancer Vaccines are Expected to a Hold Significant Market Share in the Cancer Vaccines Market
A recombinant vaccine is a vaccine produced through recombinant DNA technology. This includes DNA encoding an antigen, which stimulates an immune response into mammalian cells, expressing the antigen in these cells and then purifying it from them. Many different viruses have been genetically modified to express tumour-associated antigens (TAA) for intramuscular or subcutaneous injection.
Poxviruses have several beneficial features as vectors for cancer vaccines, including broad cell tropism, potent immunogenicity, and pre-existing neutralizing immunity, only in those patients who received the vaccinia virus (the smallpox vaccine). Vaccinia virus, fowlpox virus, and canarypox virus have been investigated clinically for cancer vaccination.
Furthermore, numerous studies are being conducted in the field of viral recombinant cancer vaccines, which may reap positive results in future, primarily related to cancer vaccination. This is expected to aid the market’s growth. For instance, In July 2019, Oxford Vacmedix UK Limited (OVM), a UK-based biopharma company collaborated and issued Innovate UK grant to CHAIN Biotechnology Ltd and the University of Oxford to develop OVM-100, a recombinant overlapping peptide (ROP) HPV vaccine targeted at cervical cancer.
However, the recent COVID 19 pandemic has posed a significant negative impact on the respective segment by delaying the development activities of recombinant cancer vaccines.
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North America Dominates the Market Over the Forecast Period
North America is expected to grow due to the high prevalence of cancer, along with developed healthcare infrastructure in the region. The United States has a better healthcare infrastructure than most developed countries. The National Cancer Institute (NCI) stated that the national spending on cancer care is expected to reach USD 156 billion by 2020.
According to the estimates of the GLOBOCAN, in 2020, an estimated 1,95,499 new cases of cancer were diagnosed in Mexico, and 90,222 people died from the disease. The rising number of cancer cases are creating opportunities for market players.
The major market players are focusing on R&D activities to bring new and reliable treatments to the market. In December 2020, Anixa Biosciences a San Jose, California based biotech company in partnership with Cleveland Clinic received USFDA investigational new drug application for its new breast cancer vaccine technology developed by Cleveland Clinic immunologist Dr Vincent Tuohy, and his research team to start the first human clinical trials.
Providence Therapeutics is a Toronto based clinical stage biotechnology company that develops cancer vaccines for human use. Currently company is developing a personalized mRNA cancer vaccine designed to generate strong T cell responses that aim to kill cancer cells and destroy tumors in ovarian cancer, breast cancer and brain cancer.
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The global cancer vaccines market is consolidated and consists of a few major players. Market players are adopting different growth strategies to enhance their market presence, such as partnerships, agreements, collaborations, mergers, and acquisitions. Companies, like AstraZeneca PLC, Bristol-Myers Squibb, GlaxoSmithKline, Roche, Merck & Co. Inc., OSE Immunotherapeutics, Sanofi, and Moderna among others, hold substantial shares in the cancer vaccines market.
- In March 2021: eTheRNA, a Belgian based immunotherapy company received a EURO 6.9 million grant from the European Commission to accelerate the clinical development of mRNA-based vaccines for cervical cancers.
- In November 2020: Moderna, Inc. release interim data from the expansion cohort of its ongoing Phase 1 study of its mRNA personalized cancer vaccine (PCV) mRNA-4157 in combination with Merck’s Keytruda and results demonstrated that the vaccine candidate is well tolerated at all dose levels and produced responses as measured by tumour shrinkage in HPV(-)Head and Neck Squamous Cell Carcinoma (HNSCC) patients.
Table of Contents
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Growing Burden of Cancer
4.2.2 Rising Investments and Government Funding in the Development of Cancer Vaccines
4.2.3 Technological Developments in Cancer Vaccines
4.3 Market Restraints
4.3.1 Stringent Regulatory Guidelines and Longer Timelines Required for Manufacturing Process
4.3.2 Presence of Alternative Therapies
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION
5.1 By Technology
5.1.1 Recombinant Cancer Vaccines
5.1.2 Whole-cell Cancer Vaccines
5.1.3 Viral Vector and DNA Cancer Vaccines
5.1.4 Other Technologies (Dendritic Cells, Antigen, etc.)
5.2 By Treatment Method
5.2.1 Preventive Vaccine
5.2.2 Therapeutic Vaccine
5.3 By Application
5.3.1 Prostate Cancer
5.3.2 Cervical Cancer
5.3.3 Other Applications
5.4.1 North America
188.8.131.52 United States
184.108.40.206 United Kingdom
220.127.116.11 Rest of Europe
18.104.22.168 South Korea
22.214.171.124 Rest of Asia-Pacific
5.4.4 Middle East and Africa
126.96.36.199 South Africa
188.8.131.52 Rest of Middle East and Africa
5.4.5 South America
184.108.40.206 Rest of South America
6. COMPETITIVE LANDSCAPE
*List Not Exhaustive
6.1 Company Profiles
6.1.1 Anixa Biosciences, Inc.
6.1.2 AstraZeneca PLC
6.1.3 Bristol Myers Squibb Company
6.1.4 F. Hoffmann-La Roche AG (Genentech)
6.1.5 GlaxoSmithKline PLC
6.1.6 Merck & Co. Inc.
6.1.7 OSE Immunotherapeutics
6.1.8 Sanofi SA
6.1.9 Dendreon Pharmaceuticals LLC.
6.1.10 Moderna, Inc.
6.1.11 Vaccitech Limited
6.1.13 eTheRNA immunotherapies
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
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Frequently Asked Questions
What is the study period of this market?
The Global Cancer Vaccines Market market is studied from 2018 - 2026.
What is the growth rate of Global Cancer Vaccines Market?
The Global Cancer Vaccines Market is growing at a CAGR of 13.2% over the next 5 years.
What is Global Cancer Vaccines Market size in 2018?
The Global Cancer Vaccines Market is valued at 4825 Million USD in 2018.
What is Global Cancer Vaccines Market size in 2026?
The Global Cancer Vaccines Market is valued at 10175 Million USD in 2026.
Which region has highest growth rate in Global Cancer Vaccines Market?
Asia Pacific is growing at the highest CAGR over 2021- 2026.
Which region has largest share in Global Cancer Vaccines Market?
North America holds highest share in 2020.
Who are the key players in Global Cancer Vaccines Market?
- Merck & Co. Inc.
- OSE Immunotherapeutics
- GlaxoSmithKline PLC
- F. Hoffmann-La Roche AG (Genentech)
- Moderna, Inc.
Are the major companies operating in Global Cancer Vaccines Market.