Biodefense Gene Synthesis Market Size
| Study Period | 2019 - 2030 |
| Market Size (2025) | USD 435.49 Million |
| Market Size (2030) | USD 560.05 Million |
| CAGR (2025 - 2030) | 5.16% |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
| Market Concentration | Medium |
Major Players*Disclaimer: Major Players sorted in no particular order |
Biodefense Gene Synthesis Market Analysis
The Biodefense Gene Synthesis Market size is estimated at USD 435.49 million in 2025, and is expected to reach USD 560.05 million by 2030, at a CAGR of 5.16% during the forecast period (2025-2030).
The Biodefense gene synthesis market is influenced by several key factors that shape the landscape of biodefense strategies and technologies. Growing concerns over biosecurity threats, coupled with proactive government measures to combat biological risks ranging from bioterrorism and emerging infectious diseases to biowarfare agents are fueling the demand for advanced technologies like gene synthesis in biodefense. This trend stands out as a primary driver of market growth.
For instance, in March 2024, the United States Federal budget was released, and in that, a USD 20 billion fund was requested to bolster biodefense and public health preparedness and response over the next five years, from 2025-2030, via the Public Health and Social Services Emergency Fund. The influx of funds into biodefense and public health preparedness is likely to spur increased research and development activities focused on developing novel gene synthesis technologies tailored for biodefense applications. This is likely to drive the market over the forecast period.
Moreover, gene synthesis plays a crucial role in biodefense and public health. By enabling the rapid design and production of specific DNA sequences, it significantly enhances the ability to detect pathogens, develop vaccines, and create effective countermeasures. This capability is essential for responding swiftly to biological threats and outbreaks. The increased funding for biodefense is likely to accelerate advancements in these areas, potentially leading to more robust and efficient technologies. This could improve preparedness and response strategies, ultimately strengthening public health systems. which is also drive the biodefense gene synthesis market. Recently, a study published in the BioMedInformatics in December 2023, revealed that the shortening of DNA synthesis time, improvement of DNA sequencing accuracy, and continuous decline of DNA synthesis and sequencing costs have been crucial driving factors in the development of DNA-based data storage technology, which has become increasingly feasible and is widely applied in the research for pathogen, and toxins.
Thus, the aformentioned factors is likey to drive the demand for the biodefense gene synthesis market during the forecast period.
However, there are extensive regulations governing gene synthesis, espacially when it involves potentially harmful agents and this likey to hamper the overall market growth.
Biodefense Gene Synthesis Market Trends
Vaccine Development Hold Significant Market Share in the Biodefense Gene Synthesis Market
Gene synthesis enables the design and production of customized vaccines tailored to specific biosecurity threats, including bioterrorism agents and emerging infectious diseases. The ability to engineer vaccine candidates with precise genetic sequences enhances their efficacy and specificity in targeting pathogens. This feature of gene synthesis is likely to drive the segment growth in the biodefense gene synthesis market.
Moreover, favorable government investment and the evolution of gene synthesis technologies empower researchers to swiftly develop vaccine prototypes in response to newly identified biosecurity threats, which is expected to boost the segment grwoth. For instance, in September 2023, CEPI (Coalition for Epidemic Preparedness Innovations) announced a renewed collaboration with Global Affairs Canada, securing CAD 1 million in funding. This financial boost aims to expedite the development of vaccines targeting emerging infectious diseases. The funding underscores CEPI's commitment to addressing the biological security challenges of the 21st century.
Similarly, in June 2024, the Biomedical Advanced Research and Development Authority, part of the United States Administration for Strategic Preparedness and Response, announced to invest USD 500 million in project NextGen in order to execute multiple Phase 2b clinical trials evaluating novel vaccines administered as a nasal spray or as a pill to protect against symptomatic COVID-19.
Thus, favorable collaboration, invesment form the goverment and effective features of gene synthesis in the vaccine development process serves as a primary driver of innovation, research, and market growth within the biodefense gene synthesis and this drive the segment market growth.
North America is Expected to Hold a Significant Market Share Over the Forecast Period
The primary growth drivers of the biodefence gene synthesis market in North America are the increasing investment and initiatives by the government and rapid technological advancements. In the North America region, the United States dominated the market.
For instance, In February 2024, the United States based Nuclear Threat Initiative, a United States based security organization focused on reducing nuclear and biological threats, launched International Biosecurity and Biosafety Initiative for Science (IBBIS). IBBIS partners with governments, global organizations, industries, and academic institutions to craft and advocate for innovative tools, empowering stakeholders to mitigate risks in the bioscience and biotechnology R&D lifecycle.
Additionally, in August 2023, the Department of Defense released the Biodefense Posture Review, outlining reforms aimed at the department's posture to fight and win in the face of future threats. The Biodefense Posture Review was a whole enterprise that came together during COVID-19 response efforts and, building on that collaboration, developed guidance to achieve National Defense Strategy priorities and address biological threats, especially those with strategic consequences for the US military. The high number of initiatives taken by government agencies for biodefense is expected to boost the market expansion during the forecast period.
Therefore, factors such as rapid technological advancements, increasing investments and initiatives by governments are some factors that drive the biodefense gene synthesis market in the North America region.
Biodefense Gene Synthesis Industry Overview
The biodefense gene synthesis market is competitive and consists of a few major players. Companies, like Synbio Technologies, Azenta Life Sciences , Bio Basic Inc., Telesis Bio, Integrated DNA Technologies, Inc., Creative Biogen, Eurofins Genomics, Origene, GenScript Biotech and DNA Script SAS among others hold substantial market shares in the biodefense gene synthesis market. New product developments, acquisitions, collaborations, and regional expansions are some of the key strategic initiatives undertaken by major players to maintain stability in the market.
Biodefense Gene Synthesis Market News
- October 2024: Fabentech secured a USD 22 million loan from the European Investment Bank (EIB) through the European HERA Invest mechanism. This funding aims to expedite R&D and bioproduction efforts, bolstering Europe's preparedness and prevention measures against health emergencies, especially in light of both deliberate and natural biological threats.
- April 2022: Heat Biologics, Inc. announced a strategic partnership through its Scorpion Biological Services subsidiary with the State of Kansas. Under this partnership, with the State of Kansas and various local and university affiliates, the company aims to establish a cutting-edge biomanufacturing facility in Manhattan, Kansas. This facility will focus on biodefense, specializing in large molecules and biologics.
Biodefense Gene Synthesis Industry Segmentation
As per the scope of the report, biodefense gene synthesis refers to the use of gene synthesis technology to support biodefense efforts. This involves designing and synthesizing DNA sequences to help prevent, detect, or respond to biological threats.
The biodefense gene synthesis market is segmented by application. In terms of application, the market is segmented as vaccine development, pathogen detection, antimicrobial resistance studies, and others By geography the market is segmented into North America, Europe, Asia-Pacific, and Rest of the World.The report offers the value (in USD) for the above segments.
| By Application | Vaccine Development | ||
| Pathogen Detection | |||
| Antimicrobial Resistance Studies | |||
| Others | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Rest of the World | |||
| Vaccine Development |
| Pathogen Detection |
| Antimicrobial Resistance Studies |
| Others |
| North America | United States |
| Canada | |
| Mexico | |
| Europe | Germany |
| United Kingdom | |
| France | |
| Italy | |
| Spain | |
| Rest of Europe | |
| Asia-Pacific | China |
| Japan | |
| India | |
| Australia | |
| South Korea | |
| Rest of Asia-Pacific | |
| Rest of the World |
Biodefense Gene Synthesis Market Research FAQs
How big is the Biodefense Gene Synthesis Market?
The Biodefense Gene Synthesis Market size is expected to reach USD 435.49 million in 2025 and grow at a CAGR of 5.16% to reach USD 560.05 million by 2030.
What is the current Biodefense Gene Synthesis Market size?
In 2025, the Biodefense Gene Synthesis Market size is expected to reach USD 435.49 million.
Which is the fastest growing region in Biodefense Gene Synthesis Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in Biodefense Gene Synthesis Market?
In 2025, the North America accounts for the largest market share in Biodefense Gene Synthesis Market.
What years does this Biodefense Gene Synthesis Market cover, and what was the market size in 2024?
In 2024, the Biodefense Gene Synthesis Market size was estimated at USD 413.02 million. The report covers the Biodefense Gene Synthesis Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Biodefense Gene Synthesis Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
Biodefense Gene Synthesis Industry Report
Statistics for the 2025 Biodefense Gene Synthesis market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Biodefense Gene Synthesis analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
