Gene Synthesis Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Report Covers Gene Synthesis Companies and the Market is Segmented by Method (Oligonucleotide Synthesis and Gene Assembly), End User (Academic and Research Institute, Biopharmaceutical Companies, and Contract Research Organizations), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Market values are Provided (in USD million) for the above segments.

Gene Synthesis Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Gene Synthesis Market Size

Gene Synthesis Market Summary
Study Period 2019 - 2030
Base Year For Estimation 2024
Forecast Data Period 2025 - 2030
Historical Data Period 2019 - 2023
CAGR 8.00 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Gene Synthesis Market Major Players

*Disclaimer: Major Players sorted in no particular order

Compare market size and growth of Global Gene Synthesis Market with other markets in Healthcare Industry

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Healthcare IT

Medical Devices

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Device Drug Combination

Gene Synthesis Market Analysis

The Global Gene Synthesis Market is expected to register a CAGR of 8% during the forecast period.

The COVID-19 pandemic has impacted the gene synthesis market in both ways, negatively and positively. At the start of the COVID-19 pandemic, most of the businesses and research activities around the world ceased due to the increasing rate of infection from the SARS-CoV-2 virus which not only reduced the use of gene synthesizers in laboratories but also the demand for it in the market. But in the quest for developing vaccines against the virus infection, which was rising in every corner of the world, the gene synthesizers played a very crucial role in the research and development of the vaccine as some of the vaccines are mRNA based and due to its efficiency too. For example, in January 2022, the Food and Drug Administration provided second approval to the mRNA-based COVID-19 vaccine from Moderna called Spikevax. Therefore, gene synthesis played a crucial role during the COVID-19 pandemic, and the market is expected to grow further.

The factors that are responsible for the growth of the Gene Synthesis market include increasing research and development in the field of genomics and next-generation sequencing, increased government funding for genomics, and increasing demand for personalized medicine and therapeutics for different chronic diseases. As personalized medicine aims to provide tailor-made therapies to individual patients, depending on the molecular basis of the disease, it has become popular over recent years. Healthcare technology, genomics, connected devices, big data analytics, and artificial intelligence are generating vast amounts of health-related data and insights which is enabling healthcare providers to offer better and faster diagnostics and treatment services by making more informed treatment decisions. In addition, gene synthesis is also finding its applications in the molecular diagnosis of infectious and genetic diseases. Genetic tests, which can detect genetic variations and predict how a person is likely to respond to certain drugs, are becoming commercially available. Therefore, increasing focus on personalized medicine and other factors, such as a patient-centered approach, are driving the growth of the gene synthesis market.

Factors, such as the aging global population and the rising prevalence of chronic diseases, are putting unrelenting pressure on the capacity and financial viability of the healthcare systems across the world and will also play a role in the driving growth of the gene synthesis market. Personalized medicine holds the promise of providing better patient care and a high safety margin while lowering total healthcare costs. As per the data published in December 2021 by International Diabetes Federation (IDF), there were about 537 million adults (20-79 years) who were living with diabetes in 2021 all over the globe and the federation projected that this number would rise to 783 million by 2045. The lack of skilled professional is the major restraining factor for the growth of the gene synthesis market as the devices are overly complex and needs special attention while handling and it's very difficult to find an expert professional for handling. Another factor that will also have a role in the inhibition of the market growth is the excessive cost and complexity of the devices.

Gene Synthesis Industry Overview

The gene synthesis market is moderately competitive and consists of several major players. In terms of the market share, few of the major players currently dominate the market. Owing to the increasing number of diseases and rising drug discovery processes, few other smaller players are expected to enter the market. Some of the major players of the market are Merck KGaA, Genscript, Genewiz Inc., Eurofins Genomics, and Bio Basic Inc., among others.

Gene Synthesis Market Leaders

  1. Merck KGaA

  2. Genewiz Inc.

  3. Eurofins Genomics

  4. Thermo Fisher Scientific

  5. GenScript

  6. *Disclaimer: Major Players sorted in no particular order
Gene Synthesis Market Concentration
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Gene Synthesis Market News

  • In July 2022, OraSure Technologies launched its OmniGene Gut DNA and RNA product (OMR-205) for gut microbiome researchers.
  • In April 2022, DNA Script launched an early access program for their SYNTAX system customers under which organizations receive early access to the latest advancements of their enzymatic DNA synthesis technology.

Gene Synthesis Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing R&D in the Field of Genomics and Next Generation Sequencing
    • 4.2.2 Increased Government Funding Toward Genomics
    • 4.2.3 Increasing Demand for Personalized Medicine
  • 4.3 Market Restraints
    • 4.3.1 Lack of Skilled Professionals
    • 4.3.2 High Cost and Complexity of Techniques
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Method
    • 5.1.1 Oligonucleotide Synthesis
    • 5.1.1.1 Solid Phase Phosphoramidite Synthesis
    • 5.1.1.2 Microchip-based Oligonucleotide Synthesis
    • 5.1.2 Gene Assembly
    • 5.1.2.1 Ligation-mediated Assembly
    • 5.1.2.2 PCR-mediated Assembly
  • 5.2 By End User
    • 5.2.1 Academic and Research Institutes
    • 5.2.2 Biopharmaceutical Companies
    • 5.2.3 Contract Research Organizations
  • 5.3 Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Italy
    • 5.3.2.5 Spain
    • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
    • 5.3.3.1 China
    • 5.3.3.2 Japan
    • 5.3.3.3 India
    • 5.3.3.4 Australia
    • 5.3.3.5 South Korea
    • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle East and Africa
    • 5.3.4.1 GCC
    • 5.3.4.2 South Africa
    • 5.3.4.3 Rest of Middle East and Africa
    • 5.3.5 South America
    • 5.3.5.1 Brazil
    • 5.3.5.2 Argentina
    • 5.3.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 ATUM (DNA2.0 Inc.)
    • 6.1.2 Bio Basic Inc.
    • 6.1.3 Beijing SBS Genetech Co. Ltd
    • 6.1.4 Eurofins Genomics
    • 6.1.5 Azenta (Genewiz Inc.)
    • 6.1.6 Genscript
    • 6.1.7 Merck KGaA
    • 6.1.8 OriGene Technologies Inc.
    • 6.1.9 Thermo Fisher Scientific Inc. (GeneArt)
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape Covers - Business Overview, Financials, Products and Strategies, and Recent Developments
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Gene Synthesis Industry Segmentation

As per the scope of the report, gene synthesis refers to the in vitro, base-by-base synthesis of double-stranded DNA molecules. Unlike DNA replication, which occurs in-vivo or by polymerase chain reaction (PCR), gene synthesis does not require a template strand for its initiation. The Gene Synthesis Market is Segmented by Method (Oligonucleotide Synthesis and Gene Assembly), End User (Academic and Research Institute, Biopharmaceutical Companies, And Contract Research Organizations), And Geography (North America, Europe, Asia-Pacific, Middle East and Africa, And South America). The Report Offers the Value (in USD Million) For the Above Segments.

By Method Oligonucleotide Synthesis Solid Phase Phosphoramidite Synthesis
Microchip-based Oligonucleotide Synthesis
Gene Assembly Ligation-mediated Assembly
PCR-mediated Assembly
By End User Academic and Research Institutes
Biopharmaceutical Companies
Contract Research Organizations
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
South America Brazil
Argentina
Rest of South America
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Gene Synthesis Market Research FAQs

What is the current Global Gene Synthesis Market size?

The Global Gene Synthesis Market is projected to register a CAGR of 8% during the forecast period (2025-2030)

Who are the key players in Global Gene Synthesis Market?

Merck KGaA, Genewiz Inc., Eurofins Genomics, Thermo Fisher Scientific and GenScript are the major companies operating in the Global Gene Synthesis Market.

Which is the fastest growing region in Global Gene Synthesis Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Global Gene Synthesis Market?

In 2025, the North America accounts for the largest market share in Global Gene Synthesis Market.

What years does this Global Gene Synthesis Market cover?

The report covers the Global Gene Synthesis Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Gene Synthesis Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Gene Synthesis Industry Report

Statistics for the 2025 Global Gene Synthesis market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Gene Synthesis analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.