Analytical Instrumentation In Life Science Market Size and Share

Analytical Instrumentation In Life Science Market (2025 - 2030)
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Analytical Instrumentation In Life Science Market Analysis by Mordor Intelligence

The analytical instrumentation in life science market size stood at USD 20.45 billion in 2025 and is forecast to reach USD 31.18 billion by 2030, reflecting an 8.09% CAGR. Heightened biologics development, stricter regulatory expectations for real-time process control, and accelerating precision-medicine programs are the primary engines behind this expansion.[1]FDA, “Content and Review of CMC Information for Human Somatic Cell Therapy INDs,” fda.gov Growing demand for high-resolution mass spectrometry, chromatography innovations that support continuous manufacturing, and artificial-intelligence-powered data analytics continue to widen the application scope of next-generation instruments. Asia-Pacific records the fastest uptake as regional CDMOs standardize high-throughput screening, while North America capitalizes on its established R&D infrastructure to maintain value leadership.[2]ISPE, “Navigating the Asia Pacific Pharmaceutical Landscape for Global Impact,” ispe.org Competitive activity is typified by scale-building acquisitions that bundle instruments, software, and consumables into integrated workflow solutions.

Key Report Takeaways

  • By product type, chromatographs led with 29.8% revenue share in 2024, while spectrometers are tracking the highest 8.2% CAGR through 2030.
  • By end-user, the pharmaceutical segment held 60.1% of the analytical instrumentation in life science market share in 2024; biopharmaceutical and nutraceutical applications are advancing at a 9.1% CAGR.
  • By geography, North America commanded 39.4% revenue in 2024, whereas Asia-Pacific is projected to expand at a 9.5% CAGR to 2030.

Segment Analysis

By Type of Product: Spectrometers drive innovation beyond traditional boundaries

The spectrometer category contributed USD 7.1 billion to the analytical instrumentation in life science market size in 2025 and is set to grow at an 8.2% CAGR through 2030. Liquid chromatographs preserved a 67.4% slice of chromatography revenue, but ion chromatographs now register 8.4% growth on the back of trace-impurity testing mandates. Orbitrap Astral Zoom debuted in 2025 with 35% faster scan rates, enabling real-time peptide-mapping of complex biologics and cementing high-resolution MS as the preferred platform for cell-therapy analytics. Gas-chromatography vendors respond to helium shortages by integrating hydrogen-safety interlocks and nitrogen-switch kits, limiting carrier-gas costs for QC labs. Micro-XRF instruments gain traction for non-destructive elemental mapping in controlled-release tablet coatings, extending their reach beyond traditional materials science. Novel gas analyzers oriented toward bioprocess monitoring now post 9.3% annual growth, reflecting the shift toward continuous biomanufacturing workflows that rely on in-line CO₂ and O₂ analytics.

Second-generation spectrometers further reduce acquisition costs per data point, widening adoption in mid-tier firms without diluting analytical power. As instrument throughput rises, consumable vendors bundle ultralow-void columns and high-capacity trapping cartridges, creating a holistic ecosystem that enhances vendor lock-in. The analytical instrumentation in life science market therefore benefits from hardware, software, and reagent co-development that optimizes complete workflows rather than isolated instrument performance.

Analytical Instrumentation In Life Science Market: Market Share by Type of Product
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By End User Vertical: Biopharmaceuticals reshape analytical requirements

The pharmaceutical segment captured 60.1% revenue in 2024, but biopharmaceutical manufacturing is projected to outpace it, expanding at 9.1% CAGR and lifting the collective analytical instrumentation in life science market size for biologics to USD 12.9 billion by 2030. API producers still account for 63.7% of pharmaceutical purchases, yet outsourcing to contract development and manufacturing organizations (CDMOs) is accelerating at 10.2%, creating distributed demand across North American and Asian service hubs.

WuXi Biologics expanded Worcester capacity to 36,000 liters, underlining the scale of analytical demand embedded in multiproduct biologics sites. Samsung Biologics’ 784,000-liter campus exemplifies how mega-facilities integrate hundreds of chromatography, spectroscopy, and in-line PAT stations to maintain consistent viral-vector output. Nutraceutical producers increasingly adopt pharmaceutical-grade validation, leveraging mid-range LC-MS and FT-IR instruments for ingredient authentication and micro-contaminant surveillance. The convergence of end-user requirements encourages platform instrument designs that deliver compliance flexibility across a spectrum of therapeutic and wellness products.

Geography Analysis

North America retained 39.4% of 2024 revenue behind its advanced biomanufacturing infrastructure and earliest adoption of continuous-processing guidance. The region’s regulatory rigor drives consistent upgrades to high-resolution instruments, and domestic stimulus packages direct USD-scale investments toward on-shore manufacturing resilience.

Asia-Pacific is the fastest-growing territory, operating at a 9.5% CAGR to 2030 as CDMOs scale capacity and governments offer tax incentives for single-use bioreactors and PAT equipment. India’s generics sector and Singapore’s biologics corridor draw multinational firms that demand standardized QC platforms compatible with global filings, lifting the analytical instrumentation in life science market across the region. China’s CRO industry exceeded CNY 64.77 billion in 2023 and continues to import premium LC-MS and UHPLC systems to service complex molecule pipelines.

Europe holds steady growth as PIC/S alignment simplifies multinational instrument validation. Waters’ USD 45 million Longbridge plant triples local orbitrap component capacity, underscoring sustained European demand for precision manufacturing inputs. South America is an emerging buyer base; Shimadzu’s Mexico subsidiary seeks 150% sales growth by 2028, signalling regional appetite for tier-one instruments. Middle East and Africa remain early-stage but attract pilot-scale investments tied to vaccine self-sufficiency programs, foreshadowing incremental instrument shipments aligned to GMP facility buildouts.

Analytical Instrumentation In Life Science Market CAGR (%), Growth Rate by Region
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Competitive Landscape

The analytical instrumentation in life science market is moderately consolidated; the top five suppliers control 49% of 2024 global revenue, with Thermo Fisher holding 23%. Multi-year acquisition pipelines aim to secure integrated software, consumables, and services that elevate switching costs. Thermo Fisher’s USD 4.1 billion purchase of Solventum’s purification unit extends its downstream-processing footprint and reinforces cross-selling of chromatography and filtration consumables. Agilent’s USD 925 million BioVectra buy-out strengthens the firm’s RNA-based therapeutics service offering, pairing sample-prep instrumentation with custom manufacturing capacity.

Waters, Danaher, and Bruker focus on differentiated high-resolution MS, GC-MS, and FT-IR systems, embedding AI-driven analytics to boost operator productivity. Waters’ BioResolve Protein A column achieves 7× sensitivity gains, underscoring how consumables innovation supports hardware competitiveness. Bruker integrates DART ionization for faster therapeutic-drug monitoring, broadening clinical applicability of its timsTOF platform. Medium-sized specialists leverage modular designs to serve niche workflows such as in-line gas analysis and mini-XRF food testing, cultivating defensible positions despite scale disadvantages.

Platform-level digital ecosystems emerge as the next battleground. Vendors that couple secure cloud data lakes with predictive-maintenance algorithms create visible ROI for labs facing skilled-labor shortages. Continuous expansion of subscription-based software revenue shields margin in an environment where instrument hardware is incrementally commoditizing.

Analytical Instrumentation In Life Science Industry Leaders

  1. Agilent Technologies

  2. Thermo Fisher Scientific

  3. Waters Corporation

  4. Bruker Corporation

  5. Shimadzu Scientific

  6. *Disclaimer: Major Players sorted in no particular order
Analytical Instrumentation In Life Science Market Concentration
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Recent Industry Developments

  • June 2025: Thermo Fisher unveiled Orbitrap Astral Zoom and Orbitrap Excedion Pro, increasing scan speeds by 35% and multiplexing by 50%, targeting biopharma and omics workflows.
  • June 2025: Waters introduced BioResolve Protein A columns with MaxPeak Premier to boost antibody-titer sensitivity 7× and enable aggregate analyses.
  • June 2025: Bruker showcased DART integration and timsMetabo for PFAS detection, expanding routine clinical and environmental applications.
  • April 2025: Thermo Fisher committed USD 2 billion to U.S. innovation, allotting USD 500 million to R&D for next-generation analytical platforms.
  • April 2025: QIAGEN outlined three sample-prep instrument launches by 2026 to enhance lab automation and reduce plastic waste
  • February 2025: Thermo Fisher agreed to acquire Solventum’s purification and filtration business for USD 4.1 billion, aiming for mid-to-high single-digit organic growth.

Table of Contents for Analytical Instrumentation In Life Science Industry Report

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET LANDSCAPE

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Surge in Demand of Analytical Instrumentation in Pharmaceutical Industry
    • 4.2.2 Expansion of Cell and Gene Therapy Pipeline Necessitating High-Resolution Characterization
    • 4.2.3 Regulatory Push for In-Line Process Analytical Technology (PAT) in Continuous Manufacturing
    • 4.2.4 Growing Public-Private Funding in Omics and Biomarker Research
    • 4.2.5 Rising Potency of Novel Drug Modalities Requiring Ultra-Sensitive Detection
    • 4.2.6 Accelerated Adoption of High-Throughput Screening by Asian CDMOs
  • 4.3 Market Restraints
    • 4.3.1 High Initial Cost
    • 4.3.2 Shortage of Skilled Analytical Chemists and Data Scientists
    • 4.3.3 Data Integrity and Validation Compliance Burden (ALCOA+ requirements)
    • 4.3.4 Complex Preventive Maintenance Leading to Higher Downtime Costs
  • 4.4 Industry Ecosystem Analysis
  • 4.5 Technology Snapshot
    • 4.5.1 Automation and Miniaturization in Analytical Instruments
    • 4.5.2 AI/ML-assisted Spectral Interpretation
    • 4.5.3 Multi-Omics Data Integration Platforms
  • 4.6 Porter's Five Forces Analysis
    • 4.6.1 Bargaining Power of Buyers/Consumers
    • 4.6.2 Bargaining Power of Suppliers
    • 4.6.3 Threat of New Entrants
    • 4.6.4 Threat of Substitute Products
    • 4.6.5 Intensity of Competitive Rivalry

5. MARKET SIZE AND GROWTH FORECASTS (VALUES)

  • 5.1 By Type of Product
    • 5.1.1 Chromatographs
    • 5.1.1.1 Gas Chromatographs (GC)
    • 5.1.1.2 Liquid Chromatographs (HPLC, UHPLC)
    • 5.1.1.3 Ion Chromatographs
    • 5.1.2 Spectrometer (Mass, Elemental Analysis and Molecular Analysis)
    • 5.1.2.1 Mass Spectrometry
    • 5.1.2.1.1 LC-MS
    • 5.1.2.1.2 GC-MS
    • 5.1.2.1.3 MALDI-TOF
    • 5.1.2.2 Elemental Analysis
    • 5.1.2.2.1 ICP-MS
    • 5.1.2.2.2 ICP-OES
    • 5.1.2.3 Molecular Analysis
    • 5.1.2.3.1 FT-IR
    • 5.1.2.3.2 Raman
    • 5.1.2.3.3 UV-Vis
    • 5.1.3 Gas Analyzer
    • 5.1.3.1 Laser-Based Gas Analyzers
    • 5.1.3.2 Electrochemical Gas Analyzers
    • 5.1.3.3 Photoacoustic Gas Analyzers
    • 5.1.4 Liquid Analyzer
    • 5.1.4.1 pH/ORP Analyzers
    • 5.1.4.2 Dissolved Oxygen (DO) Analyzers
    • 5.1.4.3 Conductivity and Total Organic Carbon (TOC) Analyzers
    • 5.1.5 Analytical X-ray Instrumentation and Analytical Microscopes
    • 5.1.5.1 X-ray Diffraction (XRD)
    • 5.1.5.2 X-ray Fluorescence (XRF)
    • 5.1.5.3 Electron Microscopes (SEM, TEM)
    • 5.1.5.4 Atomic Force Microscopes (AFM)
  • 5.2 By End User Vertical
    • 5.2.1 Biopharmaceutical and Nutraceutical
    • 5.2.1.1 Biologics Manufacturers
    • 5.2.1.2 Nutraceutical Producers
    • 5.2.2 Pharmaceutical
    • 5.2.2.1 Active Pharmaceutical Ingredient (API) Manufacturers
    • 5.2.2.2 Contract Research and Manufacturing Organizations (CROs/CDMOs)
  • 5.3 By Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Nordics
    • 5.3.2.5 Rest of Europe
    • 5.3.3 South America
    • 5.3.3.1 Brazil
    • 5.3.3.2 Rest of South America
    • 5.3.4 Asia-Pacific
    • 5.3.4.1 China
    • 5.3.4.2 Japan
    • 5.3.4.3 India
    • 5.3.4.4 South-East Asia
    • 5.3.4.5 Rest of Asia-Pacific
    • 5.3.5 Middle East and Africa
    • 5.3.5.1 Middle East
    • 5.3.5.1.1 Gulf Cooperation Council Countries
    • 5.3.5.1.2 Turkey
    • 5.3.5.1.3 Rest of Middle East
    • 5.3.5.2 Africa
    • 5.3.5.2.1 South Africa
    • 5.3.5.2.2 Rest of Africa

6. COMPETITIVE LANDSCAPE

  • 6.1 Market Concentration
  • 6.2 Strategic Moves (M&A, Partnerships, Product Launches)
  • 6.3 Market Share Analysis
  • 6.4 Company Profiles {(includes Global level Overview, Market level overview, Core Segments, Financials as available, Strategic Information, Market Rank/Share for key companies, Products and Services, and Recent Developments)}
    • 6.4.1 Thermo Fisher Scientific Inc.
    • 6.4.2 Agilent Technologies Inc.
    • 6.4.3 Waters Corporation
    • 6.4.4 Shimadzu Corporation
    • 6.4.5 Bruker Corporation
    • 6.4.6 Danaher Corporation (SCIEX and Pall)
    • 6.4.7 PerkinElmer Inc.
    • 6.4.8 Mettler Toledo International Inc.
    • 6.4.9 Sartorius AG
    • 6.4.10 Merck KGaA (MilliporeSigma)
    • 6.4.11 Bio-Rad Laboratories Inc.
    • 6.4.12 Malvern Panalytical Ltd.
    • 6.4.13 Metrohm AG
    • 6.4.14 JASCO Corporation
    • 6.4.15 JEOL Ltd.
    • 6.4.16 LECO Corporation
    • 6.4.17 Anton Paar GmbH
    • 6.4.18 HORIBA Ltd.
    • 6.4.19 Tecan Group Ltd.
    • 6.4.20 Hitachi High-Tech Corporation

7. MARKET OPPORTUNITIES AND FUTURE OUTLOOK

  • 7.1 White-Space and Unmet-Need Assessment
  • 7.2 Emerging Opportunities in Point-of-Need Microfluidic Analyzers
  • 7.3 Integration of Real-Time Release Testing (RTRT)
  • 7.4 Digital Twin and Predictive Maintenance for Analytical Labs
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Global Analytical Instrumentation In Life Science Market Report Scope

Analytical instrumentation in the life science industry helps analyze the materials, establish the composition, quality control, drug discovery, and research and development. The scope of the study includes the revenue accrued from the sale of various types of analytical instruments for various applications in the life sciences industry. This segment includes industries such as pharmaceuticals and biopharmaceuticals - establishments engaged in manufacturing medicinal and pharmaceutical products.

The analytical instrumentation market in the lifesciences industry is segmented by type of product (chromatographs, spectrometer (mass, elemental analysis, and molecular analysis), gas analyzer, liquid analyzer, and analytical x-ray instrumentation and analytical microscopes), end-user vertical (the biopharmaceutical and nutraceutical, and pharmaceutical) and geography (North America, Europe, Asia-Pacific, Rest of the World). The market sizes and forecasts are provided in terms of value in (USD) for all the above segments.

By Type of Product
Chromatographs Gas Chromatographs (GC)
Liquid Chromatographs (HPLC, UHPLC)
Ion Chromatographs
Spectrometer (Mass, Elemental Analysis and Molecular Analysis) Mass Spectrometry LC-MS
GC-MS
MALDI-TOF
Elemental Analysis ICP-MS
ICP-OES
Molecular Analysis FT-IR
Raman
UV-Vis
Gas Analyzer Laser-Based Gas Analyzers
Electrochemical Gas Analyzers
Photoacoustic Gas Analyzers
Liquid Analyzer pH/ORP Analyzers
Dissolved Oxygen (DO) Analyzers
Conductivity and Total Organic Carbon (TOC) Analyzers
Analytical X-ray Instrumentation and Analytical Microscopes X-ray Diffraction (XRD)
X-ray Fluorescence (XRF)
Electron Microscopes (SEM, TEM)
Atomic Force Microscopes (AFM)
By End User Vertical
Biopharmaceutical and Nutraceutical Biologics Manufacturers
Nutraceutical Producers
Pharmaceutical Active Pharmaceutical Ingredient (API) Manufacturers
Contract Research and Manufacturing Organizations (CROs/CDMOs)
By Geography
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Nordics
Rest of Europe
South America Brazil
Rest of South America
Asia-Pacific China
Japan
India
South-East Asia
Rest of Asia-Pacific
Middle East and Africa Middle East Gulf Cooperation Council Countries
Turkey
Rest of Middle East
Africa South Africa
Rest of Africa
By Type of Product Chromatographs Gas Chromatographs (GC)
Liquid Chromatographs (HPLC, UHPLC)
Ion Chromatographs
Spectrometer (Mass, Elemental Analysis and Molecular Analysis) Mass Spectrometry LC-MS
GC-MS
MALDI-TOF
Elemental Analysis ICP-MS
ICP-OES
Molecular Analysis FT-IR
Raman
UV-Vis
Gas Analyzer Laser-Based Gas Analyzers
Electrochemical Gas Analyzers
Photoacoustic Gas Analyzers
Liquid Analyzer pH/ORP Analyzers
Dissolved Oxygen (DO) Analyzers
Conductivity and Total Organic Carbon (TOC) Analyzers
Analytical X-ray Instrumentation and Analytical Microscopes X-ray Diffraction (XRD)
X-ray Fluorescence (XRF)
Electron Microscopes (SEM, TEM)
Atomic Force Microscopes (AFM)
By End User Vertical Biopharmaceutical and Nutraceutical Biologics Manufacturers
Nutraceutical Producers
Pharmaceutical Active Pharmaceutical Ingredient (API) Manufacturers
Contract Research and Manufacturing Organizations (CROs/CDMOs)
By Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Nordics
Rest of Europe
South America Brazil
Rest of South America
Asia-Pacific China
Japan
India
South-East Asia
Rest of Asia-Pacific
Middle East and Africa Middle East Gulf Cooperation Council Countries
Turkey
Rest of Middle East
Africa South Africa
Rest of Africa
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Key Questions Answered in the Report

What is the current size of the analytical instrumentation in life science market?

The analytical instrumentation in life science market reached USD 20.45 billion in 2025 and is projected to expand to USD 31.18 billion by 2030.

Which region is growing the fastest?

Asia-Pacific is the fastest-growing region, posting a 9.5% CAGR through 2030 due to expanding CDMO capacity and government incentives.

Which product segment shows the highest growth?

Spectrometers, particularly high-resolution mass-spectrometry platforms, are forecast to grow at an 8.2% CAGR through 2030 as biologics characterization needs intensify.

Who are the leading companies in this market?

Thermo Fisher Scientific leads with 23% revenue share, followed by Agilent Technologies, Waters Corporation, Danaher, and Bruker.

How is regulation influencing instrument demand?

Stricter FDA and EMA guidance on continuous manufacturing and PAT drives real-time analytical adoption, boosting demand for in-line chromatography and mass-spectrometry systems.

What key challenge could slow market growth?

High capital expenditure and a shortage of skilled analytical chemists remain significant barriers, potentially curbing instrument deployment in resource-constrained settings.

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