Manufacturers focus highly on extraction conditions, as the extraction conditions of beta-glucan are highly responsible for the ratio of the soluble and insoluble fraction. High solubility of soluble beta-glucan enables companies to produce products with a smooth texture.​ Soluble beta-glucan finds its applications increasingly in the cosmetics industry to manufacture creams and lotions, as it can be easily absorbed into the skin to achieve desired cosmetic or dermatologic results.​ Manufacturers are offering soluble beta-glucan that has higher water solubility compared to insoluble beta-glucan, thereby making it ideal for a wide array of applications.​ For instance, Tate & Lyle, offers PromOat Beta Glucan, a soluble oat bran fiber extracted from wholegrain oats and is free from chemicals. It is soluble and has strong water-binding and emulsifying properties, smooth and creamy texture in a variety of products, including beverages, dairy, soups, sauces, and dressings.

In the healthcare industry, beta-glucans are used for improving immune response and are used as oral medicines or injections for treating a range of medical diseases and disorders including high cholesterol, Crohn’s disease, diabetes, cancer, and high blood pressure.​ Moreover, an increasing number of research studies have been carried out using beta-glucans to treat a range of chronic inflammatory skin diseases and other health conditions. Such research studies involve the usage of topical creams containing beta-glucan to study the effect of the medications for treating the disease.​ Thus, the increasing applications of beta-glucan in the healthcare industry have led to manufacturers offering beta-glucan to carry out research studies and introduce potent drugs.