Spine Biologics Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The Spine Biologics Market is segmented By Product (Bone Graft Substitutes, Spinal Allografts, Others), By End User and Geography.

Market Snapshot

Spine Biologics Market Size
Study Period: 2018 - 2026
Base Year: 2021
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 4 %
Spine Biologics Market Major Players

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Market Overview

The Spine Biologics Market is expected to register a CAGR of 4% during the forecast period. This is attributing to the growing geriatric population, rising prevalence of spine deformities, and technological advancements in bone grafting procedures. In addition, rising incidences of degenerative spine disorders with a significant increase in treatment rates and increasing preference for minimally invasive procedures are also fueling the growth of the market. Moreover, interbody fusion and direct lateral interbody fusion are the two advanced biological mechanisms for the treatment of the deformity of the spine and are highly adopted among surgeons globally. Furthermore, Advancements in the biomaterial and minimally invasive procedure approach associated with lateral body fusion is an ideal approach for the treatment of spine disorders as this procedure results in safe, effective, fast recovery and less injury. It further promotes the demand for spine biologics in the treatment of disc generation, sclerosis and other spine-related disorders. Spine injuries are very common among the population who are above 50 years as they are more susceptible to have structural alteration in the spine or spinal impairments thus growing geriatric population around worldwide will also promote the demand of treatment and diagnosis of the disorders. Therefore, the aforementioned factors will drive the spine biologics market in forecasted period.

Scope of the Report

As per the scope, Spine biologics comprises biomaterials that are used in the treatment of spinal cord injuries, degenerative disc diseases, and bone fusion surgeries. It mainly stimulates the growth of bone formation by different stages which involve inflammatory, repair, and remodeling. Spine Biologics Market is segmented By Product, End-User, and Geography.

By Product
Bone Graft Substitutes
Bone Morphogenetic Proteins
Synthetic Bone Grafts
Spinal Allografts
Machined Bones Allograft
Demineralized Bone Matrix
By End User
Ambulatory Surgical Centers
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle East and Africa
South Africa
Rest of Middle East and Africa
South America
Rest of South America

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Key Market Trends

Spinal Allografts in Spinal Biologics is Estimated to Witness a Healthy Growth in Future

Spinal allografts are estimated to witness healthy growth in the future which is attributed to several benefits associated with its usage. Spinal allografts are the allograft bone that is donated from another patient (donor) and used in the spine treatment procedure. The use of allografts in spinal fusion will eliminate the additional surgical procedure that is reduced surgery time. In addition, these are osteoconductive which means it provides a scaffold to the spine repair. Moreover, several companies are working and providing on natural bone grafts that are harvested from the donor body. For instance, Zimmer Biomet offers RegenerOss Resorbable Xenograft (natural bone grafts). Products from such international and well-established companies indicate the demand for spinal allografts in the market.

Spine Biologics Market Share

North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period

North America is expected to hold a significant market share in the global Spine Biologics Market due to the presence of the geriatric population, increasing adoption of minimally invasive procedure, and rising prevalence of spine disorders such as spondylolisthesis, spinal stenosis, and disc-related issue. As per the American Association of Neurological Surgeons, every year an estimate of 17,000 new cases of spinal cord injury reported in the United States. Thus a large number of spinal cord injury population will significantly promote the demand for the treatment of disorders wherein spinal biologics plays an important role in diagnosis and thereby driving the overall market The United States owns the largest share of Spine Biologics Market in the North America region Furthermore, well-established infrastructure, stable economic growth, growing health care expenditure is also expected to fuel the Spine Biologics Market in this region.

Spine Biologics Market Growth

Competitive Landscape

The Spine Biologics Market is moderately competitive and consists of several major players. Some of the companies which are currently dominating the market are Johnson & Johnson (Depuy Synthes), Orthofix Medical Inc., Stryker Corporation, Zimmer Biomet, Arthrex, Inc., Exactech, Inc, Medtronic plc, etc.

Major Players

  1. Orthofix Medical Inc

  2. Zimmer Biomet

  3. Arthrex, Inc.

  4. Johnson & Johnson (Depuy Synthes)

  5. Stryker Corporation

Johnson & Johnson (Depuy Synthes), Orthofix Medical Inc., Stryker Corporation, Zimmer Biomet, Arthrex, Inc., Exactech, Inc, Medtronic plc

Table of Contents


    1. 1.1 Study Assumptions and Market Definition​

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Geriatric Population

      2. 4.2.2 Growing Prevalence of Spine Deformities

      3. 4.2.3 Technological Advancements

    3. 4.3 Market Restraints

      1. 4.3.1 Reimbursement Policies

    4. 4.4 Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Product

      1. 5.1.1 Bone Graft Substitutes

        1. Bone Morphogenetic Proteins

        2. Synthetic Bone Grafts

      2. 5.1.2 Spinal Allografts

        1. Machined Bones Allograft

        2. Demineralized Bone Matrix

      3. 5.1.3 Others

    2. 5.2 By End User

      1. 5.2.1 Hospitals

      2. 5.2.2 Ambulatory Surgical Centers

      3. 5.2.3 Others

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle East and Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Johnson And Johnson (Depuy Synthes)

      2. 6.1.2 Orthofix Medical Inc.

      3. 6.1.3 Stryker Corporation

      4. 6.1.4 Zimmer Biomet

      5. 6.1.5 Arthrex, Inc.

      6. 6.1.6 Exactech, Inc

      7. 6.1.7 Spine Wave, Inc.

      8. 6.1.8 Medtronic plc

      9. 6.1.9 NuVasive, Inc.

    2. *List Not Exhaustive

**Competitive Landscape includes Business Overview, Financials, Products and Strategies, and Recent Developments
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Frequently Asked Questions

The Spine Biologics Market market is studied from 2018 - 2026.

The Spine Biologics Market is growing at a CAGR of 4% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2021.

Orthofix Medical Inc, Zimmer Biomet, Arthrex, Inc., Johnson & Johnson (Depuy Synthes), Stryker Corporation are the major companies operating in Spine Biologics Market.

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