Schizophrenia Drugs Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The Schizophrenia Drugs Market is Segmented by Therapeutic Class (Second-generation Antipsychotics, Third-generation Antipsychotics, and Other Therapeutic Classes), Treatment (Oral and Injectables), and Geography (North America, Europe, Asia Pacific, Middle East and Africa, and South America). The report offers the value (in USD billion) for the above segments.

Market Snapshot

Schizophrenia Drugs Market Summary
Study Period: 2019-2027
Base Year: 2021
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 3.24 %
Schizophrenia Drugs Market Major Players

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Market Overview

The schizophrenia drugs market is expected to register a CAGR of 3.24% during the forecast period (2022 - 2027).

The emergence of the COVID-19 pandemic had its impact on the schizophrenia market as all the procedures including diagnostic and therapeutic around the world were impacted due to the decline in visits to hospitals and diagnostic centers because of lockdown restrictions imposed by various governments globally. Further, many studies reported the negative impact of COVID-19 on patients with schizophrenia disorder, which is also expected to impact the studied market. According to an article published, in May 2020, titled "Schizophrenia and COVID-19 delirium", COVID-19 has had a substantial impact on the global population, and people with schizophrenia are at a higher risk of infection and its consequences due to difficulties adhering to preventive protocols and the existence of other medical comorbidities. As per the same source, infected schizophrenia patients may experience more severe symptoms than others. Similarly, according to an article published by the Europe PMC, in 2020, titled "COVID-19 paranoia in a patient suffering from schizophrenic psychosis", the COVID-19 pandemic triggered COVID-19--related hallucinations and delusions, along with changes in the patient's mood making it aggressive. Hence, the COVID-19 pandemic is having a significant negative impact on the lives of people with schizophrenia. However, with the resumed services and procedures, the schizophrenia drugs market is expected to regain its full potential over the forecast period.

The increasing incidence and prevalence of schizophrenia and associated disorders and mental illness, increasing focus of government and health care organizations on mental health, and rising investments in research and development activities by the market players are all projected to increase the growth of the market over the forecast period.

The increasing prevalence of schizophrenia and associated disorders along with the rising geriatric population, who is more susceptible to late-onset schizophrenia, is the key factor driving the growth of the market over the forecast period. For instance, according to the World Health Organization, in 2022, schizophrenia affects 24 million people, worldwide. Furthermore, this number is likely to continue to increase, along with the growth in the aging population. According to the World Population Ageing Highlight 2020 report published by the United Nations, the global geriatric population is increasing rapidly around the world and in 2020, about 727 million people of age 65 years or more were living across the world which was about 9.3% of the total global population. As per the same source, it is anticipated that there will be 1.5 billion people of age 65 years or above in the world, by 2050. Additionally, the American Psychiatric Association and the National Institute of Mental Health estimated that the risk of an individual having schizophrenia at some point in their life is between 0.3% and 0.7%.

Furthermore, the market is likely to be driven by a growth in the number of patients receiving treatment and rising demand for improved healthcare infrastructure. In recent years, governments in several countries have worked closely with numerous institutions across the globe to provide better protection to those suffering from schizophrenia. The expanding prevalence of the condition, as well as the growing need to effectively manage it, are driving the market over the forecast period.

However, the increasing cases of addiction associated with these drugs and the patent expiry of major drugs are hampering the overall market growth.

Scope of the Report

As per the scope of the report, Schizophrenia is characterized by delusions, hallucinations, and other cognitive difficulties, which can often be a lifelong struggle. It is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. People with schizophrenia may seem like they have lost touch with reality. Although schizophrenia is not as common as other mental disorders, the symptoms can be disabling. The schizophrenia drugs market is segmented by therapeutic class (second-generation antipsychotics, third-generation antipsychotics, and other therapeutic classes), treatment (oral and injectables), and geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Therapeutic Class
Second-generation Antipsychotics
Third-generation Antipsychotics
Other Therapeutic Classes
By Treatment
Oral
Injectables
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia Pacific
China
Japan
India
Australia
South Korea
Rest of Asia Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America

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Key Market Trends

The Second-generation Antipsychotics Segment Expects to Register a High CAGR in the Forecast Period

The Second-generation antipsychotics segment is expected to grow over the forecast period, owing to the factors such as the rising prevalence of mental health disorders including schizophrenia, highly effective in treating symptoms like hallucinations and delusions in patients with schizophrenia.

According to an article published in November 2020, titled "Effectiveness of antipsychotic drugs in schizophrenia: a 10-year retrospective study in a Korean tertiary hospital", the study results showed that among antipsychotics, clozapine has the best efficacy for treatment continuation. In addition to clozapine, aripiprazole and paliperidone, have also been demonstrated to be the most effective in treating schizophrenia.

Furthermore, the increasing company focus on developing effective drug products for treating patients with schizophrenia and rising product approvals are also contributing to the growth of the antipsychotic drugs segment, thereby boosting the market growth over the period. For instance, in June 2021, the United States Food and Drug Administration approved Alkermes’s Lybalvi, an oral antipsychotic drug composed of olanzapine, for schizophrenia and bipolar I disorder. In addition, in September 2021, the United States Food and Drug Administration approved Janssen's Invega Hafyera, a long-acting atypical antipsychotic drug, the first-and-only twice-yearly injectable for the treatment of schizophrenia in adults.

As a result, improving efficacy and effectiveness in treating schizophrenia, as well as increasing company focus on developing atypical antipsychotic drugs for treating schizophrenia, are likely to fuel market expansion throughout the projection period.

Schizophrenia Drugs Market : Number of Active Schizophrenia Clinical Trials, By Phase, Global, As of July 2022

North America is Expected to Have the Significant Market Share

North America is expected to hold a major market share in the schizophrenia drugs market due to the increasing prevalence of schizophrenia and related mental disorders in the population, rising geriatric population, presence of robust healthcare infrastructure and high healthcare spending, and presence of major market players.

The increasing burden of mental illness and schizophrenia in the population is the key factor driving the market growth in the region. According to the June 2022 update of the National Alliance of Mental Illness (NAMI), the annual prevalence of schizophrenia among adults in the United States is about 1.5 million people, and thus, schizophrenia drugs are expected to be in demand in the region which will boost growth in the studied market in North America. In addition to this, Schizophrenia typically affects men in their late teens or early twenties and women in their late twenties or early thirties. Similarly, according to the World Health Organization, in 2022, people with schizophrenia are two to three times more likely to die early than the general population. This is often due to physical illnesses, such as cardiovascular, metabolic, and infectious diseases.

Furthermore, the company is mainly focusing on adopting various business strategies such as collaborations, product launches, acquisitions, and partnerships to withhold their position in the schizophrenia drugs market is likely to boost the market growth. For instance, in November 2021, Neurocrine Biosciences partnered with Sosei Group Corporation to develop a new brand of protein inhibitor that helps to improve treatments for a wide range of neuropsychiatric disorders. Under the agreement, Neurocrine Biosciences has the right to develop and produce muscarinic M4, M1, and dual M1/M4 receptor agonists discovered by Sosei Heptares. In addition, Neurocrine Biosciences plans to submit an Investigational New Drug Application to the Food and Drug Administration and begin a placebo-controlled phase 2 study with one of the M4 agonists as a potential schizophrenia treatment, by 2022. Similarly, in June 2020, Neurocrine Biosciences entered into a strategic collaboration with Takeda Pharmaceuticals to develop and commercialize compounds in Takeda’s early-to-mid-stage psychiatry pipeline. Under the collaboration, Takeda granted an exclusive license to Neurocrine Biosciences for seven pipeline programs, including three clinical-stage assets for schizophrenia, treatment-resistant depression, and anhedonia.

Hence, the increasing burden of mental illness, schizophrenia, and related disorders among people, increasing focus and research and development activities by the market players, and other factors are likely to increase the market expansion over the forecast period.

Schizophrenia Drugs Market - Growth Rate By Region

Competitive Landscape

The schizophrenia drugs market is highly competitive and consists of major and small players. In terms of market share, major players currently dominate the market. Some of the major market players include Alkermes PLC, Otsuka Pharmaceuticals, Eli Lilly and Company, Johnson & Johnson, and AbbVie (Allergan PLC), among others.

Major Players

  1. Johnson & Johnson

  2. Eli Lilly and Company

  3. AbbVie Inc.(Allergan Plc)

  4. Alkermes PLC

  5. Otsuka Pharmaceutical Inc.

Schizophrenia Drugs Market Concentration

Recent Developments

  • In February 2022, Vanderbilt University  signed a worldwide license and a research collaboration agreement with Neumora Therapeutics to develop precision medicines for brain diseases through the integration of data science and neuroscience. The license program includes two new series of compounds that targets schizophrenia and other neuropsychiatric disorders.
  • In March 2022, AbbVie entered into a new co-development and license agreement with Gedeon Richter, to research, develop and commercialize novel dopamine receptor modulators for the potential treatment of neuropsychiatric diseases.

Table of Contents

  1. 1. INTRODUCTION

    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study

  2. 2. RESEARCH METHODOLOGY

  3. 3. EXECUTIVE SUMMARY

  4. 4. MARKET DYNAMICS

    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Burden of Schizophrenia and Associated Disorders

      2. 4.2.2 Increase in Focus of Governments and Health Care Organizations on Mental Health and Increasing Investments in R&D

    3. 4.3 Market Restraints

      1. 4.3.1 Increase in Cases of Addiction Associated with these Drugs

      2. 4.3.2 Patent Expiry of Major Drugs

    4. 4.4 Industry Attractiveness - Porter's Five Forces Analysis

      1. 4.4.1 Bargaining Power of Buyers/Consumers

      2. 4.4.2 Bargaining Power of Suppliers

      3. 4.4.3 Threat of New Entrants

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION

    1. 5.1 By Therapeutic Class

      1. 5.1.1 Second-generation Antipsychotics

      2. 5.1.2 Third-generation Antipsychotics

      3. 5.1.3 Other Therapeutic Classes

    2. 5.2 By Treatment

      1. 5.2.1 Oral

      2. 5.2.2 Injectables

    3. 5.3 Geography

      1. 5.3.1 North America

        1. 5.3.1.1 United States

        2. 5.3.1.2 Canada

        3. 5.3.1.3 Mexico

      2. 5.3.2 Europe

        1. 5.3.2.1 Germany

        2. 5.3.2.2 United Kingdom

        3. 5.3.2.3 France

        4. 5.3.2.4 Italy

        5. 5.3.2.5 Spain

        6. 5.3.2.6 Rest of Europe

      3. 5.3.3 Asia Pacific

        1. 5.3.3.1 China

        2. 5.3.3.2 Japan

        3. 5.3.3.3 India

        4. 5.3.3.4 Australia

        5. 5.3.3.5 South Korea

        6. 5.3.3.6 Rest of Asia Pacific

      4. 5.3.4 Middle East and Africa

        1. 5.3.4.1 GCC

        2. 5.3.4.2 South Africa

        3. 5.3.4.3 Rest of Middle East and Africa

      5. 5.3.5 South America

        1. 5.3.5.1 Brazil

        2. 5.3.5.2 Argentina

        3. 5.3.5.3 Rest of South America

  6. 6. COMPETITIVE LANDSCAPE

    1. 6.1 Company Profiles

      1. 6.1.1 Alkermes Plc

      2. 6.1.2 Abbvie (Allergan Plc)

      3. 6.1.3 AstraZeneca

      4. 6.1.4 Eli Lilly and Company

      5. 6.1.5 Johnson & Johnson

      6. 6.1.6 Pfizer Inc.

      7. 6.1.7 Sumitomo Dainippon Pharma

      8. 6.1.8 Vanda Pharmaceuticals

      9. 6.1.9 Bristol-Myers Squibb and Company

      10. 6.1.10 Otsuka America Pharmaceutical Inc.

      11. 6.1.11 Acadia Pharmaceuticals

      12. 6.1.12 Karuna Therapeutics

    2. *List Not Exhaustive
  7. 7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Frequently Asked Questions

The Global Schizophrenia Drugs Market market is studied from 2019 - 2027.

The Global Schizophrenia Drugs Market is growing at a CAGR of 3.24% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2021.

Johnson & Johnson, Eli Lilly and Company, AbbVie Inc.(Allergan Plc), Alkermes PLC, Otsuka Pharmaceutical Inc. are the major companies operating in Global Schizophrenia Drugs Market.

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