Protein Crystallization Market - Growth, Trends, Covid-19 Impact, and Forecasts (2022 - 2027)

The Protein Crystallization Market is segmented by Product (Instruments, Reagents or Consumables, Services and Software), End-User (Pharmaceutical and Biotechnology industries and Others), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The report offers the value (in USD Million) for the above segments.

Market Snapshot

Protein Crystallization Market Overview
Study Period: 2019-2027
Base Year: 2021
Fastest Growing Market: North America
Largest Market: Asia-Pacific
CAGR: 8 %

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Market Overview

The Protein Crystallization Market is projected to register a CAGR of 8% during the forecast period (2022-2027).

Amidst COVID-19, the Protein Crystallization market is expected to grow owing to the rising cases of infectious disease among the people. An increase in the demand for vaccines and protein-based therapy to overcome the COVID-19 infection is expected to boost the market's growth. Also, the extensive usage of protein crystallization to develop the COVID-19 vaccination is expected to boost the market's growth. For instance, in January 2021, Elasmogen identified protein-based drugs that can potentially stop COVID-19 infections through a partnership with the University of Minnesota. Hence, the increasing prevalence of COVID-19 is expected to positively impact the market's growth.

The increasing demand for protein therapeutics is a key factor driving the market's growth. This is because protein therapeutics have become an integral part of the health care industry over recent years. Protein therapeutics are extensively used to treat various major diseases, such as cancer, owing to their low immunogenicity and specificity. The increasing demand fro protein-based drugs and therapeutics led the manufacturers to implement growth strategies to gain the major market share, thereby increasing the market's growth. For instance, in January 2022, Amgen announced that they would partner with Generate Biomedicines to discover and create protein therapeutics for five targets across several therapeutic areas and multiple modalities. The increasing demand for protein therapeutics is due to the increasing prevalence of Chronic disease and rising awareness regarding protein therapeutics efficiency. According to the World Health Organization (WHO), an estimated 19.3 million new cancer cases worldwide and almost 10.0 million cancer deaths will occur in 2020. Such an increase in chronic disease prevalence has increased the need to develop novel and efficient drugs. Protein Crystallization is widely used in drug discovery and development, which further propels the market's growth. Advancements in protein crystallography and the implementation of standard protocols create a lucrative opportunity for market growth. Increasing application fields and areas of protein crystallization for tailoring effective drug candidates contribute to the market's growth over the forecast period.

Scope of the Report

As per the scope of this report, protein crystallization is the process of forming crystals that offer key insights into protein function and helps researchers understand the inner workings of a living cell. Protein Crystallography is widely used in the drug discovery and development process. The Protein Crystallization Market is segmented by Product (Instruments, Reagents or Consumables, Services, and Software), End-User (Pharmaceutical and Biotechnology industries, and Others), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The Market report also covers the estimated market sizes and trends of 17 countries across major regions globally. The report offers values in USD million for the above segments.

By Technology
Protein Purification systems
Protein Crystallization
Protein Crystal Mouting
Protein Crystallography
By Product
Reagents or Consumables
Services and software
By End User
Pharmaceutical and Biotechnology Industries
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Key Market Trends

The Pharmaceuticals and Biotechnology Industries Segment is Expected to Hold a Major Market Share in the Protein Crystallization Market Marke

The pharmaceutical and biotechnology industries are expected to be the most lucrative segment, with extensive usage of Protein Crystallization in their production process. The pharmaceutical industry is expected to register significant revenue growth over the forecast period owing to the increasing application of protein crystallization in the drug discovery and development process and rising demand for protein therapeutics. The increasing innovative launches to meet the growing demand are also expected to boost the market's growth. For instance, in July 2021, DeepMind company announced the release of a massive protein structure database, which will be one of the most important databases since mapping the human genome. In November 2020, Rigaku Corporation announced the launch of Rigaky HyPix-Arc 100, a curved photon counting X-ray detector for single crystal X-ray diffraction applications. Thereby, the rise in the pharmaceutical industry's research and development expenditure significantly impacts the market's growth. For instance, in 2020, in the report published by the Congressional Budget Office (CBO), the pharmaceutical industry spent over USD 83 billion on the research and development process. The report states that Research and Development costs have increased by about 8.5 percent per year over roughly the past decade. Additionally, biotechnology companies are also expected to register significant revenue over the forecast period owing to the increasing application of protein crystallization for genomic engineering, proteomics research, and protein engineering.

Protein Crystallization Market Share

North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period

The United States is likely to command the global market owing to the technological innovations in protein crystallization. Owing to the increase in the research and development activities in the biopharma sector in the United States region, the Protein Crystallization market is expected to grow in this region. The robust growth of protein crystallization can be attributed to the rising investment and funding activities for proteomics research and for the development of structure-based drugs. According to the Binder Dijker Otte (BDO) USA Reports, in 2020, companies listed on the biotechnology index (NBI) average research and development spending increased by 16%, in 2020, to USD 284.25 million in the US pharmaceutical industry. Thus the increasing research and development activities in the United States region provide lucrative opportunities for the growth of the Protein Crystallization market. Moreover, the presence of major market players and advanced technologies for product development is expected to mark this region with dominating share. Additionally, an increase in research and development activities and the presence of favorable healthcare infrastructure are fueling the growth of the overall regional market to a large extent.

Protein Crystallization Market Growth

Competitive Landscape

The Protein Crystallization Market is fragmented and competitive and consists of several major players. In terms of market share, a few of the major players are currently dominating the market. Some companies currently dominating the market are Repligen corporation, Sartorius, Cytiva, Asahi Kasei Medical Co., Ltd, Parker Hannifin Corp, Mar cor, Koch Separation solutions, Meissner Filtration Products, Inc, Antylia Scientific, Biotree, and others.

Recent Developments

In November 2021, Thermo Fisher Scientific collaborated with MSAID company, a leader in proteomics artificial intelligence, to proteomics researchers with advanced mass spectroscopy software named proteome discovery 3.0 software with CHIMERYS to substantially enhance the identification rate and the number of unique peptide identifications.

In March 2021, Bruker Corporation launched new plasma proteomics software, PaSER software v.1.1 which will allow ‘run & done’ high throughput 4D proteomics with immediate availability of identified protein groups after the experiment is done.

Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increasing investment in the Research and development of Biopharmaceuticals

      2. 4.2.2 Rising adaption of the protein therapeutics

    3. 4.3 Market Restraints

      1. 4.3.1 Lack of trained Personnel

      2. 4.3.2 High cost of the instruments

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Technology

      1. 5.1.1 Protein Purification systems

      2. 5.1.2 Protein Crystallization

      3. 5.1.3 Protein Crystal Mouting

      4. 5.1.4 Protein Crystallography

    2. 5.2 By Product

      1. 5.2.1 Instruments

      2. 5.2.2 Reagents or Consumables

      3. 5.2.3 Services and software

    3. 5.3 By End User

      1. 5.3.1 Pharmaceutical and Biotechnology Industries

      2. 5.3.2 Others

    4. 5.4 Geography

      1. 5.4.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.4.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.4.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.4.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.4.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Rigaku Corporation

      2. 6.1.2 Hampton Research Corp

      3. 6.1.3 MiteGen LLC

      4. 6.1.4 Agilient Technologies

      5. 6.1.5 Krackeler Scientific

      6. 6.1.6 SARomics Biostructures AB

      7. 6.1.7 Tecan Trading AG

      8. 6.1.8 Charles River

    2. *List Not Exhaustive

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The Global Protein Crystallization Market market is studied from 2019 - 2027.

The Global Protein Crystallization Market is growing at a CAGR of 8% over the next 5 years.

North America is growing at the highest CAGR over 2021- 2026.

Asia-Pacific holds highest share in 2021.

Agilient Technologies-, Rigaku Corporation, Hampton Research Corp, SARomics Biostructures AB, Charles River are the major companies operating in Global Protein Crystallization Market .

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