Protease Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

the Report Covers Proteases Market Revenue and It is Segmented by Source (Animal (Trypsin, Pepsin, Renin, and Other Animal Sources), Plant (Papain, Bromelain, and Other Plant Sources), and Microbial (Alkaline Protease, Acid Protease, and Neutral Protease)); by Application (Food and Beverage, Pharmaceuticals, Animal Feed, and Other Applications); and by Geography (North America, Europe, Asia-Pacific, South America, and Middle East and Africa). the Market Size and Values are Provided in Terms of (USD Million) During the Forecasted Years for the Above Segments.

Protease Market Size

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Proteases Market Summary
Study Period 2019 - 2029
Market Size (2024) USD 3.54 Billion
Market Size (2029) USD 4.72 Billion
CAGR (2024 - 2029) 6.00 %
Fastest Growing Market Middle East and Africa
Largest Market North America

Major Players

Proteases Market

*Disclaimer: Major Players sorted in no particular order


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Protease Market Analysis

The Proteases Market size is estimated at USD 3.54 billion in 2024, and is expected to reach USD 4.72 billion by 2029, growing at a CAGR of 6% during the forecast period (2024-2029).

Proteases are a diverse group of enzymes that act as proteinases, peptidases, and amidases and have a broad range of industrial applications, particularly in the food, detergents, and pharmaceutical sectors. Research has shown that proteases constitute a significant class of industrial enzymes, accounting for approximately 60% of the enzyme market and 40% of all enzyme sales worldwide. Proteases are essential industrial enzymes that break down peptide bonds in proteins and find numerous uses in chemical and biological processes. One of the main advantages of using proteases is their ability to produce natural products, exhibit activity under mild reaction conditions, and exhibit stereospecificity, specificity, and biodegradability. Companies have introduced innovative products that reduce reaction time to enhance overall yield. Proteases are crucial in developing many fast-moving consumer goods (FMCG) products. The market's primary driver is the multiple applications of proteases in various industries. Additionally, their non-toxic and non-pathogenic attributes make them eco-friendly, further boosting the market.

Protease enzymes find use in three primary applications in the food industry: meat products, baked goods, and beverages. In meat products, proteases are used to tenderize the meat, making it softer and palatable and reducing overall processing time. The global processed food industry is experiencing significant growth, driven by changing lifestyles that demand ready-to-cook/eat products. This is expected to drive the demand for proteases during the forecast period. Additionally, microbial proteases have gained interest due to their vital role in metabolic activities and their immense utilization in industries. The proteases available in the market are of microbial origin because of their high yield, less time consumption, and cost-effectiveness, which have made them suitable for biotechnological application in the market

Protease Market Trends

Rising Application of Proteases in Various Industries

Proteases are enzymes that play a significant role in various industries, making up 60% of the enzyme market. They are used in the production of detergent, leather, food, pharmaceuticals, paper, and pulp, as well as in the recovery of silver from photographic films and bioremediation procedures. Manufacturing daily essentials, such as textiles, paper, feed, food, medications, and chemicals, generates a substantial amount of waste, which is harmful to the environment and human health. Thus, the use of proteases has become crucial in increasing processing efficiency while reducing waste production and preserving natural resources. As a result, companies worldwide are searching for alternative technologies or mergers and acquisitions to meet the annual demand while consuming fewer natural resources.

For instance, in November 2022, Novozymes and LinusBio collaborated to test new, non-invasive technology in a clinical trial to assess exposure to harmful compounds. The project will leverage LinusBio's environmental biodynamics platform to map out harmful compound exposure during a clinical trial of probiotics sponsored by Novozymes' human health unit. The clinical trial will assess exposure to heavy metals, such as lead, and a broad range of environmental pollutants and is part of a larger clinical program from Novozymes OneHealth. Apart from environmental benefits, protease enzymes are widely used in the food and beverage industry to enhance food proteins' flavor, nutritional value, solubility, and digestibility. They are utilized in various applications such as brewing, coagulation of milk, and the meat industry, where proteases are used to tenderize meat products by breaking down the microfibre in the meat structure. Alkaline proteases prepare protein hydrolysates of high nutritional value with a well-defined peptide profile.

Protease enzymes have diverse applications in numerous industries. The market is expected to grow significantly in the upcoming years due to its vital role in reducing waste production, improving processing efficiency, and preserving natural resources.

Proteases Market: Per Capita Meat Consumption, in %, By Type, United States, 2022

Asia-Pacific is the Fastest-growing Market

India, China, and South Korea are some of the fastest-growing markets for processed foods globally, making the Asia-Pacific region the most productive market for protease enzymes by application. In India, the food processing industry is one of the largest in the world, and the country presents enormous growth potential for proteases. In China, rapid urbanization and income growth create a demand for high-value products, diversifying the Chinese diet and increasing the demand for protease enzymes.

South Korea has a developing processed food industry, where consumers are more inclined toward frozen processed foods and frozen meat products, especially pork meat with high-fat content. It holds the fifteenth largest market share in processed food globally. The South Korean food industry also holds greater potential for wide applications of food additives like proteases.

The expanding organized retail chains in developing regions further augment the demand for processed meat products, benefiting meat tenderizing agents, including protease. In the bakery industry, protease is used to reduce the gluten of flour, improve the plasticity of gluten, increase dough volume, improve dough toughness, and shorten dough forming time. The heightened demand for high-quality, long-shelf-life, healthy bakery products, including bread, cakes, biscuits, and others, is expected to fuel the growth of the protease enzyme segment.

In addition to food and bakery products, protease enzymes are widely used in detergents and pharmaceuticals. The Asia-Pacific region also presents untapped growth potential for protease enzymes in these industries. Overall, the Asia-Pacific region is an important market for protease enzymes and is expected to witness significant growth in the coming years.

Proteases Market: Market Size (%), By Region, Global, 2022

Protease Industry Overview

The protease market is consolidated in nature with the top players occupying major market shares. Some of the major players in this sector include International Flavors & Fragrances, Inc., Koninklijke DSM NV, Novozymes AS, BASF SA, and Associated British Foods plc. These players adopt various strategies to maintain their leading position in the market and build a strong brand image. The key strategies these players adopt are mergers and acquisitions, which help them consolidate their market position and expand their product portfolios.

Product innovation and new product developments are essential strategies, top players adopt to cater to consumer demand and preferences. Companies invest heavily in research and development activities to introduce new and improved products, which helps them to differentiate their products from their competitors and expand their customer base. Moreover, companies also focus on expanding their product portfolios by adding new product lines and acquiring new businesses. This strategy enables companies to cater to consumers' evolving needs and preferences and increase their market share.

Protease Market Leaders

  1. International Flavors & Fragrances, Inc.

  2. Novozymes A/S

  3. Koninklijke DSM NV

  4. BASF SE

  5. Associated British Foods plc

*Disclaimer: Major Players sorted in no particular order

Proteases Market Concentration
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Protease Market News

  • June 2021: Koninklijke DSM NV introduced its new protease enzyme, ProAct 360™, which enables feed producers to be more flexible in selecting and using raw materials. This helps to reduce the industry's reliance on soy and other major crops while lowering feed costs. ProAct 360 also significantly enhances protein digestibility, ensuring greater retention of nitrogen in metabolism and lower nitrogen emissions to the environment. The launch of this enzyme is part of DSM's strategy to expand its product portfolio and drive sustainable innovation in the industry.
  • March 2021: Novozymes AS launched Formea Prime, a protease enzyme developed for protein drinks using the company's enzymatic Formea platform. This new product launch is expected to help the industry produce better-tasting protein beverages for consumers. Novozymes AS is committed to leveraging its research and development capabilities to bring innovative products to market and expand its product portfolio to meet evolving customer needs.
  • February 2021: International Flavors & Fragrances merged with DuPont's Nutrition and Biosciences Business. The combined company continues to operate under the name IFF. The merger solidified IFF's place as one of the biggest players in the ingredients space.

Protease Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Drivers

    2. 4.2 Market Restraints

    3. 4.3 Porter's Five Forces Analysis

      1. 4.3.1 Threat of New Entrants

      2. 4.3.2 Bargaining Power of Buyers/Consumers

      3. 4.3.3 Bargaining Power of Suppliers

      4. 4.3.4 Threat of Substitute Products

      5. 4.3.5 Intensity of Competitive Rivalry


    1. 5.1 Source

      1. 5.1.1 Animal

        1. Trypsin

        2. Pepsin

        3. Renin

        4. Other Animal Sources

      2. 5.1.2 Plant

        1. Papain

        2. Bromelain

        3. Other Plant Sources (Keratinases and Ficin)

      3. 5.1.3 Microbial

        1. Alkaline Protease

        2. Acid Protease

        3. Neutral Protease

    2. 5.2 Application

      1. 5.2.1 Food and Beverage

        1. Dairy

        2. Bakery

        3. Beverages

        4. Meat and Poultry

        5. Infant Formula

      2. 5.2.2 Pharmaceuticals

      3. 5.2.3 Animal Feed

      4. 5.2.4 Other Applications

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

        4. Rest of North America

      2. 5.3.2 Europe

        1. Spain

        2. United Kingdom

        3. France

        4. Germany

        5. Italy

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Singapore

        5. Australia

        6. Rest of Asia-Pacific

      4. 5.3.4 South America

        1. Brazil

        2. Argentina

        3. Rest of South America

      5. 5.3.5 Middle-East and Africa

        1. South Africa

        2. United Arab Emirates

        3. Saudi Arabia

        4. Rest of Middle-East and Africa


    1. 6.1 Most Adopted Strategies

    2. 6.2 Market Share Analysis

    3. 6.3 Company Profiles

      1. 6.3.1 Novus International Inc.

      2. 6.3.2 International Flavors & Fragrances Inc.

      3. 6.3.3 Koninklijke DSM NV

      4. 6.3.4 Biocatalyst Ltd

      5. 6.3.5 Novozymes A/S

      6. 6.3.6 Advanced Enzyme Technologies

      7. 6.3.7 Associated British Foods plc

      8. 6.3.8 Bioseutica BV

      9. 6.3.9 BASF SE

      10. 6.3.10 Kemin Industries Inc.

    4. *List Not Exhaustive

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Protease Industry Segmentation

Protease is an enzyme that catalyzes the hydrolysis of peptide bonds present in proteins and has many functions, including industrial and medical purposes, like extracting gums, processing food, treating inflammation, and many others. The protease market is segmented by source, application, and geography. By source, the market is segmented into animal (trypsin, pepsin, renin, and other animal sources), plant (papain, bromelain, and other plant sources), and microbial (alkaline protease, acid protease, and neutral protease). By application, the market is segmented into food and beverage (dairy, bakery, beverages, meat and poultry, and infant formula), pharmaceuticals, animal feed, and other applications. By geography, the market is segmented by North America, Europe, Asia-Pacific, South America, and Middle East and Africa. The market sizing has been done in value terms in USD for all the abovementioned segments.

Other Animal Sources
Other Plant Sources (Keratinases and Ficin)
Alkaline Protease
Acid Protease
Neutral Protease
Food and Beverage
Meat and Poultry
Infant Formula
Animal Feed
Other Applications
North America
United States
Rest of North America
United Kingdom
Rest of Europe
Rest of Asia-Pacific
South America
Rest of South America
Middle-East and Africa
South Africa
United Arab Emirates
Saudi Arabia
Rest of Middle-East and Africa
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Protease Market Research FAQs

The Proteases Market size is expected to reach USD 3.54 billion in 2024 and grow at a CAGR of 6% to reach USD 4.72 billion by 2029.

In 2024, the Proteases Market size is expected to reach USD 3.54 billion.

International Flavors & Fragrances, Inc., Novozymes A/S, Koninklijke DSM NV, BASF SE and Associated British Foods plc are the major companies operating in the Proteases Market.

Middle East and Africa is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Proteases Market.

In 2023, the Proteases Market size was estimated at USD 3.34 billion. The report covers the Proteases Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Proteases Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Protease Industry Report

Statistics for the 2024 Proteases market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Proteases analysis includes a market forecast outlook to for 2024 to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Protease Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)