Proteases Market - Growth, Trends, COVID-19 Impact, and Forecasts (2023 - 2028)

The Proteases Market is Segmented by Source (Animal (Trypsin, Pepsin, Renin, and Other Animal Sources), Plant (Papain, Bromelain, and Other Plant Sources), and Microbial (Alkaline Protease, Acid Protease, and Neutral Protease)), Application (Food and Beverage (Dairy, Bakery, Beverages, Meat and Poultry, and Infant Formula), Healthcare, Animal Feed, and Other Applications), and Geography (North America, Europe, Asia-Pacific, South America, and Middle-East and Africa). For each segment, the market sizing and forecast have been done based on the value (in USD million).

Proteases Industry Overview

Global Proteases Market
Study Period: 2018 - 2028
Fastest Growing Market: Asia Pacific
Largest Market: Europe
CAGR: 5.8 %

Major Players


*Disclaimer: Major Players sorted in no particular order


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Proteases Market Analysis

The protease market is projected to record a CAGR of 5.8% during the forecast period (2022-2027).

The COVID19 outbreak significantly impacted the proteases market due to the closure of several manufacturing units in the first quarter of 2021. Several research studies found that proteases are promising drug targets for the antiviral treatment of COVID-19. However, drug development and therapeutics could be a highly complex process. Thereby, the demand for these enzymes from several end-user industries rose, thus positively impacting the market.

Proteases are the largest group of enzymes with an essential role in many industries, especially food, detergents, and pharmaceuticals.

Protease enzymes help improve the digestibility of some foods. They are critical for the development of many FMCG products. The main driver of the market is the multiple applications of proteases in diverse industries. Their eco-friendly nature due to their non-toxic and non-pathogenic attributes is an added advantage boosting the market.

Proteases Industry Segments

Protease is derived from three major sources: animal, plant, and microbial. The animal source includes trypsin, pepsin, renin, and other animal sources. The plant source includes papain, bromelain, and other plant sources. The microbial include alkaline protease, acid protease, and neutral protease. Proteases are extensively used in food and beverage (dairy, bakery, beverages, meat and poultry, and infant formula), healthcare, animal feed, and other applications. The report also includes a geographical analysis spanning North America, Europe, Asia-Pacific, South America, and Middle-East and Africa. For each segment, the market sizing and forecast have been done based on the value (in USD million).

By Source
Other Animal Sources
Other Plant Sources (Keratinases and Ficin)
Alkaline Protease
Acid Protease
Neutral Protease
By Application
Food and Beverage
Meat and Poultry
Infant Formula
Animal Feed
Other Applications
By Geography
North America
United States
Rest of North America
United Kingdom
Rest of Europe
Rest of Asia-Pacific
South America
Rest of South America
Middle-East and Africa
South Africa
United Arab Emirates
Saudi Arabia
Rest of Middle-East and Africa

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Proteases Market Trends

This section covers the major market trends shaping the Proteases Market according to our research experts:

Rising Application of Proteases

Protease enzymes are significantly used in the food and beverages industries to improve the flavor, nutritional value, solubility, and digestibility of food protein. This enzyme has many applications, such as brewing, coagulation of milk, and other uses. For instance, in the baking industry, for quicker preparation of dough, its gluten is partially hydrolyzed by a heat-labile fungal protease because of its early inactivation in subsequent baking. Alkaline proteases are used to prepare protein hydrolysates of high nutritional value with a well-defined peptide profile. They also play a crucial role in meat tenderization, especially beef. Among the seafood products, food enzymes, particularly protease, are catalyzed for their benefits, such as improving oil separation and higher yield. They help save energy and enhance protein value and digestibility. They also offer better functional properties, such as emulsification, solubility, fat- and water-binding, and improved removal of residual meat, to achieve ‘clean’ fish frames for use as a source of calcium.

Proteases Market 1

Asia-Pacific is the Fastest-growing Market

Asia-Pacific is the fastest-growing region as it comprises countries with the highest population. This factor has made Asia-Pacific the most productive market for protease enzymes by applications. The region also presents untapped growth potential for protease enzymes in food, detergents, and pharmaceutical products. The protease market is witnessing rapid growth due to the increasing demand for processed food and animal feed in the region and the wide applications of enzymes, including in the processed food industry. These enzymes are used to reduce the mixing time, decrease dough consistency and uniformity, regulate the gluten strength in bread, and improve the texture and flavor. Due to the growing usage of proteases, the demand is escalating, which is further driving the market.

Proteases Market 2

Proteases Market Competitor Analysis

The proteases market is mature due to the presence of several domestic and global players. The major players in this sector are DuPont, Koninklijke DSM NV, Novozymes AS, Advanced Enzyme Technologies, and Merck KGaA. The key strategies adopted by these players are mergers and acquisitions, which help them sustain a leading position in the market and build a strong brand image. Some other top players adopt product innovations and new product developments as their key strategies to cater to consumer demand and preferences. Companies also engage in product innovation to expand their product portfolios.

Proteases Market Top Players

  1. E. I. Du Pont De Nemours and Company

  2. Advanced Enzyme Technologies

  3. Merck KGaA

  4. Koninklijke DSM NV

  5. Novozymes AS

*Disclaimer: Major Players sorted in no particular order

protease market.PNG

Proteases Market Recent Developments

  • In 2021, Koninklijke DSM NV launched its new proteases enzyme ProAct 360™, which will likely help feed producers be more flexible in their selection and use of raw materials, thus reducing the industry’s reliance on soy and other major crops while helping cut feed costs. It also significantly enhances protein digestibility, ensuring greater retention of nitrogen in the metabolism and lower nitrogen emissions to the environment. The major strategy behind the company's shift toward new product development is to expand its product portfolio.
  • In 2021, Novozymes AS launched Formea® Prime, a protease enzyme built on Novozymes’ enzymatic Formea®platform, which was developed for protein drinks. According to the company, this new product launch may help the industry produce better-tasting protein beverages for consumers.
  • In 2020, DuPont Nutrition & Biosciences announced the launch of Versilk in North America. It is one of the latest products in its range of enzymes that may help yogurt and beverage manufacturers achieve an optimal texture and taste in yogurts, dairy beverages, and other fermented beverages. New product developments can help the firm accelerate its business by expanding its portfolio.

Proteases Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Drivers

    2. 4.2 Market Restraints

    3. 4.3 Porter's Five Forces Analysis

      1. 4.3.1 Threat of New Entrants

      2. 4.3.2 Bargaining Power of Buyers/Consumers

      3. 4.3.3 Bargaining Power of Suppliers

      4. 4.3.4 Threat of Substitute Products

      5. 4.3.5 Intensity of Competitive Rivalry


    1. 5.1 By Source

      1. 5.1.1 Animal

        1. Trypsin

        2. Pepsin

        3. Renin

        4. Other Animal Sources

      2. 5.1.2 Plant

        1. Papain

        2. Bromelain

        3. Other Plant Sources (Keratinases and Ficin)

      3. 5.1.3 Microbial

        1. Alkaline Protease

        2. Acid Protease

        3. Neutral Protease

    2. 5.2 By Application

      1. 5.2.1 Food and Beverage

        1. Dairy

        2. Bakery

        3. Beverages

        4. Meat and Poultry

        5. Infant Formula

      2. 5.2.2 Healthcare

      3. 5.2.3 Animal Feed

      4. 5.2.4 Other Applications

    3. 5.3 By Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

        4. Rest of North America

      2. 5.3.2 Europe

        1. Spain

        2. United Kingdom

        3. France

        4. Germany

        5. Italy

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Singapore

        5. Australia

        6. Rest of Asia-Pacific

      4. 5.3.4 South America

        1. Brazil

        2. Argentina

        3. Rest of South America

      5. 5.3.5 Middle-East and Africa

        1. South Africa

        2. United Arab Emirates

        3. Saudi Arabia

        4. Rest of Middle-East and Africa


    1. 6.1 Market Share Analysis

    2. 6.2 Strategies Adopted by Players

    3. 6.3 Most Active Companies

    4. 6.4 Company Profiles

      1. 6.4.1 Abbott Laboratories

      2. 6.4.2 E. I. Du Pont De Nemours and Company

      3. 6.4.3 Koninklijke DSM NV

      4. 6.4.4 Novozymes AS

      5. 6.4.5 Advanced Enzyme Technologies

      6. 6.4.6 Merck KGaA

      7. 6.4.7 Tate & Lyle PLC

      8. 6.4.8 Amano Enzyme Inc.

      9. 6.4.9 Dyadic International Incorporated

      10. 6.4.10 Tereos SA

    5. *List Not Exhaustive


**Subject to Availability
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Proteases Market Research FAQs

The Proteases Market is studied from 2018 - 2028.

The Proteases Market is growing at a CAGR of 5.8% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2018 - 2028.

Europe holds highest share in 2021.

E. I. Du Pont De Nemours and Company, Advanced Enzyme Technologies, Merck KGaA, Koninklijke DSM NV, Novozymes AS are the major companies operating in Proteases Market.

Proteases Industry Reports

In-depth industry statistics and market share insights of the Proteases sector for 2020, 2021, and 2022. The Proteases research report provides a comprehensive outlook of the market size and an industry growth forecast for 2023 to 2028. Available to download is a free sample file of the Proteases report PDF.

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