Live Cell Encapsulation Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The Market Report Covers Global Encapsulation Companies and is Segmented by Manufacturing Technique (Simple Dripping, Electrostatic Dripping, Coaxial Airflow, Rotating Disk Atomization, Others), Polymer Type (Alginate, Chitosan, Silica, Cellulose Sulfate, Others), Application (Drug Delivery, Regenerative Medicine, Cell Transplantation, Others), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The value is provided in (USD million) for the above segments.

Live Cell Encapsulation Market Size

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Live Cell Encapsulation Market Summary
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Study Period 2019 - 2029
Base Year For Estimation 2023
Forecast Data Period 2024 - 2029
CAGR 3.20 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Live Cell Encapsulation Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Live Cell Encapsulation Market Analysis

The live-cell encapsulation market is expected to increase with a CAGR of nearly 3.2% during the forecast period.

The Live-cell encapsulation market was significantly impacted by COVID-19. However, various COVID-19 vaccines are RNA encapsulated, impacting market growth over the pandemic period. For instance, according to the study published in the Journal of Virus Research in October 2021, 1273 mRNA is a vaccine made up of synthetic mRNA encapsulated in lipid nanoparticles (LNPs) that codes for SARS-full-length, CoV-2's pre-fusion stabilized spike protein. Additionally, in May 2021, Moderna and the Vaccine Research Centre worked on an mRNA-based vaccine candidate encapsulating the mRNA in lipid nanoparticles, while Codagenix worked on a live attenuated viral vaccine in collaboration with the Serum Institute of India. Thus, the use of live cell encapsulation procedures in the development of COVID-19 treatment therapies during the pandemic had a notable impact on the market growth. In addition, the demand for live cell encapsulation is expected to remain intact due to the increasing focus on developing treatment therapies against the mutant strain of SARS-CoV-2, fueling the market's growth over the forecast period.

The major factors, such as increasing research programs to establish the clinical efficacy of the cell encapsulation process, are expected to boost market growth. The rising application of live cell encapsulation in developing treatment therapies for major chronic diseases like diabetes, cancers, autoimmune diseases, etc., is also expected to contribute to the market's growth over the forecast period. For instance, according to the study published in the NGP Asia Material in May 2022, blood glucose levels and body weights improved with live cell porous microcapsules encasing cells. These characteristics suggest that porous microcapsules encasing cells are effective in treating diabetes, and researchers believe that because of their superior capabilities, this method will be widely used in the clinic. Thus, the efficacy of live cell encapsulation therapy in treating diabetes is expected to drive the demand for live cell encapsulation, thereby boosting the market's growth over the forecast period.

Moreover, the rising diabetes population worldwide is expected to drive the demand for live cell encapsulation for the development of innovative therapies, thereby contributing to the market's growth. For instance, as per the September 2021 report by the International Diabetes Federation, Diabetes affected approximately 537 million adults (20-79 years) in 2021. By 2030, the total number of diabetes is expected to reach 643 million; by 2045, it will reach 783 million. Thus, the rising number of cases creates a huge opportunity for the market player to bring the novel live cell encapsulated drug for treating people with diabetes, expected to boost the market growth.

Furthermore, another major driving factor accrediting the growth of the live-cell encapsulation market is rising public-private investments to fund product development. For instance, in July 2021, Austrianova developed a novel and proprietary technology for encapsulating living mammalian (Cell-in-a-Box) and bacterial (Bac-in-a-Box) cells using cellulose sulfate-based materials received an investment from Real Tech. Such investments in the development of live cell encapsulation are expected to contribute to the market's growth.

However, the high cost of good-quality raw materials and adopting alternative therapies are major factors restraining the market's growth.

Live Cell Encapsulation Market Trends

This section covers the major market trends shaping the Live Cell Encapsulation Market according to our research experts:

Drug Delivery Segment is Expected to be the Major Contributor to the Live Cell Encapsulation market

Live cell encapsulation produces tablets, capsules, and parenteral dosage forms and is widely used in drug delivery systems. The increasing use of cell encapsulation for drug delivery drives this segment's growth, owing to its procedural advantages, such as improved efficacy, reduced toxicity, and improved patient condition.

The advantages of live cell encapsulated drug delivery include high efficacy, tolerability, and patient compliance. For instance, according to the Elsevier study article published in October 2021, live cell encapsulation improves drug solubility and permeability, bioavailability, reduces side effects, and improves therapeutic efficiency while providing preferential accumulation of active molecules at specific tissue sites or cells. Thus, the advantages of live-cell encapsulation in drug delivery are expected to drive the demand for live-cell encapsulation, thereby anticipated to boost segment growth.

Additionally, various market players involved in developing encapsulated drug deliveries and market player strategies are also expected to contribute to the market's growth. For instance, in May 2022, Pancryos signed a licensing deal with Brigham and Women's Hospital to develop microencapsulation for treating type 1 diabetes. Similarly, in February 2021, ViaCyte Inc. announced initiating a phase 2 study of encapsulated cell therapy for type 1 diabetes patients. The study will advance a leading encapsulated cell therapy candidate to replace the insulin-producing cells lost in type 1 diabetes.

Thus, all factors above, such as the efficacy of live cell encapsulation in drug delivery product developments by various market players and the rising prevalence of chronic diseases such as diabetes, are anticipated to boost segment growth over the forecast period.

Live Cell Encapsulation Market - Estimated Number of Diabetes Cases (in Million), Global, 2021-2045

North America is Expected to Hold a Significant Share in the Live Cell Encapsulation Market Over the Forecast Period

North America is expected to dominate the overall live-cell encapsulation market throughout the forecast period. The market growth is due to factors such as the presence of key players, increasing per capita healthcare expenditure, increasing funding and investment for research and development programs in the United States and Canada, and established healthcare infrastructure are the key factors accountable for its large share in the market.

According to a report published in September 2021 by the Pharmaceutical Research and Manufacturers of America (PhRMA), Untill 2021, biopharmaceutical companies invested more than a trillion dollars in research and development, PhRMA member companies invested about USD 91 billion in research and development Additionally, the in December 2021, Government of Alberta announced USD 5.6 million funding to strengthen Alberta's life sciences and pharmaceutical sector in Canada. Thus, increasing research and development spending along with high investments is expected to create a huge opportunity for the market players in order to develop advanced therapies involving live cell encapsulation procedures, thereby contributing to the growth of the market.

Furthermore, rising product developments by various market players in the region are expected to boost market growth. For instance, in November 2021, PharmaCyte Biotech, Inc., a biotechnology company focused on developing cellular therapies for cancer and diabetes using its signature live-cell encapsulation technology, Cell-in-a-Box, recently confirmed that the empty capsule material used in its CypCapsTM pancreatic cancer product does not irritate the skin and can be brought into the market. Thus, such product developments are expected to contribute to the growth of the market over the forecast period.

Thus, all aforementioned factors, such as increasing investments in research and development and rising funding from the government along with the presence of key market players, are anticipated to boost the market over the forecast period.

Live Cell Encapsulation Market - Growth Rate by Region

Live Cell Encapsulation Industry Overview

The live-cell encapsulation market is relatively competitive and consists of several major players. Some of the companies which are currently dominating the market are Viacyte, Inc, Living Cell Technologies Limited., Diatranz Otsuka Ltd, PharmaCyte Biotech Inc., Sernova Corporation, Sigilon Therapeutics, Inc., BÜCHI Labortechnik AG, Blacktrace Holdings Ltd.

Live Cell Encapsulation Market Leaders

  1. Living Cell Technologies Limited.

  2. Viacyte, Inc.

  3. Diatranz Otsuka Ltd

  4. PharmaCyte Biotech Inc.

  5. Atelerix Ltd

*Disclaimer: Major Players sorted in no particular order

Live Cell Encapsulation Market Concentration
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Live Cell Encapsulation Market News

  • In November 2022, Bio INX launched Hydrobio INX 400, the boring enabling live cell encapsulation in 3D printing with Nanoscribe's two-photon polymerization technology. The material is designed with the ability for cell encapsulation in combination with cell seeding to fabricate complex biomimetic tissues.
  • In March 2022, PharmaCyte Biotech, Inc. reported successfully completing a 24-month product stability study required by the United States Food and Drug Administration (FDA) for its clinical trial product candidate, CypCaps. The significance of this time point is that CypCaps has now demonstrated a shelf life of at least 24 months when stored at -80 celsius.

Live Cell Encapsulation Market Report - Table of Contents

  1. 1. INTRODUCTION

    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study

  2. 2. RESEARCH METHODOLOGY

  3. 3. EXECUTIVE SUMMARY

  4. 4. MARKET DYNAMICS

    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Growing Public-Private Investments in the Biotechnology Research

      2. 4.2.2 Increasing Research to Establish the Clinical Efficacy of Cell Encapsulation

      3. 4.2.3 Rising Public Awareness for Role of Encapsulated Cells in Disease Management

    3. 4.3 Market Restraints

      1. 4.3.1 Limited Availability of Good Quality Raw Material

      2. 4.3.2 Adoption of Alternative Therapies

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 5.1 By Manufacturing Technique

      1. 5.1.1 Simple Dripping

      2. 5.1.2 Electrostatic Dripping

      3. 5.1.3 Coaxial Airflow

      4. 5.1.4 Rotating Disk Atomization

      5. 5.1.5 Others

    2. 5.2 By Polymer Type

      1. 5.2.1 Alginate

      2. 5.2.2 Chitosan

      3. 5.2.3 Silica

      4. 5.2.4 Cellulose Sulfate

      5. 5.2.5 Others

    3. 5.3 By Application

      1. 5.3.1 Drug Delivery

      2. 5.3.2 Regenerative Medicine

      3. 5.3.3 Cell Transplantation

      4. 5.3.4 Others

    4. 5.4 Geography

      1. 5.4.1 North America

        1. 5.4.1.1 United States

        2. 5.4.1.2 Canada

        3. 5.4.1.3 Mexico

      2. 5.4.2 Europe

        1. 5.4.2.1 Germany

        2. 5.4.2.2 United Kingdom

        3. 5.4.2.3 France

        4. 5.4.2.4 Italy

        5. 5.4.2.5 Spain

        6. 5.4.2.6 Rest of Europe

      3. 5.4.3 Asia-Pacific

        1. 5.4.3.1 China

        2. 5.4.3.2 Japan

        3. 5.4.3.3 India

        4. 5.4.3.4 Australia

        5. 5.4.3.5 South Korea

        6. 5.4.3.6 Rest of Asia-Pacific

      4. 5.4.4 Middle East and Africa

        1. 5.4.4.1 GCC

        2. 5.4.4.2 South Africa

        3. 5.4.4.3 Rest of Middle East and Africa

      5. 5.4.5 South America

        1. 5.4.5.1 Brazil

        2. 5.4.5.2 Argentina

        3. 5.4.5.3 Rest of South America

  6. 6. COMPETITIVE LANDSCAPE

    1. 6.1 Company Profiles

      1. 6.1.1 Viacyte, Inc.

      2. 6.1.2 Living Cell Technologies Limited.

      3. 6.1.3 Diatranz Otsuka Ltd

      4. 6.1.4 PharmaCyte Biotech Inc

      5. 6.1.5 Sernova Corp

      6. 6.1.6 Sigilon Therapeutics, Inc.

      7. 6.1.7 Buchi Labortechnik AG

      8. 6.1.8 Blacktrace Holdings Ltd.

      9. 6.1.9 Atelerix Ltd.

      10. 6.1.10 Neurotech Pharmaceuticals, Inc

      11. 6.1.11 Kadimastem

      12. 6.1.12 Austrianova

    2. *List Not Exhaustive
  7. 7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Live Cell Encapsulation Industry Segmentation

As per the scope of the report, live-cell microencapsulation is a technology that involves immobilizing the cells inside a polymeric semi-permeable membrane that allows the bidirectional diffusion of molecules essential for cell metabolism and the outward diffusion of products. Simultaneously, the semi-permeable nature of the membrane prevents immune cells and antibodies from damaging the encapsulated cells considering them as particles. The Live Cell Encapsulation Market is segmented by Manufacturing Technique (Simple Dripping, Electrostatic Dripping, Coaxial Airflow, Rotating Disk Atomization, Others), Polymer Type (Alginate, Chitosan, Silica, Cellulose Sulfate, Others), Application (Drug Delivery, Regenerative Medicine, Cell Transplantation, Others), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Manufacturing Technique
Simple Dripping
Electrostatic Dripping
Coaxial Airflow
Rotating Disk Atomization
Others
By Polymer Type
Alginate
Chitosan
Silica
Cellulose Sulfate
Others
By Application
Drug Delivery
Regenerative Medicine
Cell Transplantation
Others
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America
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Live Cell Encapsulation Market Research FAQs

The Global Live Cell Encapsulation Market is projected to register a CAGR of 3.20% during the forecast period (2024-2029)

Living Cell Technologies Limited., Viacyte, Inc., Diatranz Otsuka Ltd, PharmaCyte Biotech Inc. and Atelerix Ltd are the major companies operating in the Global Live Cell Encapsulation Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Global Live Cell Encapsulation Market.

The report covers the Global Live Cell Encapsulation Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Global Live Cell Encapsulation Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Live Cell Encapsulation Industry Report

Statistics for the 2024 Live Cell Encapsulation market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Live Cell Encapsulation analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Live Cell Encapsulation Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)