Knee Cartilage Repair Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Knee Cartilage Repair Market report segments the industry into Application (Arthroscopic Chondroplasty, Autologous Chondrocyte Implantation, Cell-based Cartilage Resurfacing, Osteochondral Grafts Transplantation, Others), End User (Hospitals, Ambulatory Surgical Centers, Orthopedic Clinics), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, South America).

Knee Cartilage Repair Market Size

Knee Cartilage Repair Market Summary

Knee Cartilage Repair Market Analysis

The Global Knee Cartilage Repair Market is expected to register a CAGR of 6.2% during the forecast period.

During the COVID-19 pandemic, the studied market was adversely affected due to supply chain issues and long waiting times. For instance, in August 2021, a research study titled "Impact of the COVID-19 Outbreak on Orthopedic Surgery: A Nationwide Analysis of the First Pandemic Year" stated that the number of orthopedic surgeries fell by 22.8% during the first year of the pandemic in Chile. All surgical procedures were adversely affected, with fracture and trauma surgeries being the least affected. The maximum adverse impact was seen in knee arthroplasty (-64%), followed by hip arthroplasty (-41%) and knee ligament reconstruction (-44%). The COVID-19 outbreak reduced the number of orthopedic procedures during 2020, as public health networks did have a more significant adverse impact on elective surgeries due to a slower recovery than private institutions. An increase in the waiting list should be expected, which will widen the access gap to orthopedic surgery, ultimately impacting the market growth rate over the coming years.

Factors such as the increasing geriatric population coupled with increasing road and sports-related injuries and a rising preference for minimally invasive surgeries are driving the market growth. For instance, an article published by the World Health Organization titled "Age and Health" in October 2021 stated that by 2030, 1 in 6 people worldwide would be 60 years or older. The share of the population aged 60 years and over will increase from 1 billion in 2020 to 1.4 billion. By 2050, the world's population of people aged 60 years and older will double (to 2.1 billion). The number of people aged 80 years or older is expected to triple between 2020 and 2050 to reach 426 million. Aging may hurt knee health, and thus, there will be an increased chance of knee cartilage damage and thus it will require treatment. Hence, growth in the geriatric population, thereby drive the demand for knee surgeries, in turn boosting the market's growth.

Similarly, rising road accidents are another factor augmenting the market's growth. For instance, in October 2021, the National Road Safety Authority (ANSR) stated that there was a worsening in the evolution of the indicators, with a growth of 42.5% in fatalities, in contrast to the reductions of the two previous months, and an increase of 9.1% in the number of accidents, from 2.4% for serious injuries and 11.6% for minor injuries, compared to August 2020. According to the same document, in August 2021, there were 2,996 road accidents on Portuguese roads, which caused 57 deaths, 217 serious injuries, and 3,644 minor injuries. As a result, rising injuries will increase the demand for knee cartilage treatment, driving market growth in the coming years. 

Similarly, a rising preference for minimally invasive surgeries would increase market growth. For instance, in January 2021, a research study published titled "Augmented reality navigation for minimally invasive knee surgery using enhanced arthroscopy" stated that during minimally invasive knee surgery, surgeons insert surgical instruments and arthroscopy through small incisions and implement treatment assisted by 2D arthroscopic images. Compared with 2D arthroscopic navigation, the proposed augmented reality navigation reduced the targeting errors by 2.10 mm and 2.70 mm for knee phantom and in vitro swine knee experiments, respectively. Thus, with technological advancements, the preference for minimally invasive surgeries will increase and support the market's growth.

Additionally, in July 2021, the HYALEX Cartilage System by Hyalex Orthopaedics, Inc. was granted Breakthrough Device Designation by the United States Food and Drug Administration (FDA). The HYALEX Cartilage System is intended to repair cartilage defects and restore function for patients with loss of knee articular cartilage and bone requiring surgery.

Thus, the abovementioned factors will increase the market's growth in the upcoming period. However, the high cost of treatment may hinder the market's growth over the forecast period.

Knee Cartilage Repair Industry Overview

The market is partially fragmented and consists of several major players. In terms of market share, a few major players dominate the market. Some of the companies which are currently dominating the market are B. Braun Melsungen AG, ISTO Technologies, Inc., Smith & Nephew, Stryker, and Zimmer Biomet Holdings, Inc., among others.

Knee Cartilage Repair Market Leaders

  1. B. Braun Melsungen AG

  2. ISTO Technologies, Inc.

  3. Smith & Nephew

  4. Stryker

  5. Zimmer Biomet Holdings, Inc.

  6. *Disclaimer: Major Players sorted in no particular order
Knee Cartilage Repair Market Concentration
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Knee Cartilage Repair Market News

  • In March 2022, CartiHeal Ltd., a developer of implants for the treatment of cartilage and osteochondral defects in arthritic and non-arthritic knee joints, announced that the US Food and Drug Administration (FDA) had granted Premarket Approval (PMA) for its Agili-C implant.
  • In February 2022, Hy2Care BV started a clinical trial for advanced cartilage treatment with injectable-hydrogel validation of the effect. The objective of this clinical investigation is to demonstrate the clinical safety and performance of the Hy2Care Injectable hydrogel.

Knee Cartilage Repair Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Geriatric Population
    • 4.2.2 Increasing Road and Sports Related Injuries
    • 4.2.3 Increasing Preference for Minimally Invasive Surgeries
  • 4.3 Market Restraints
    • 4.3.1 High Cost of Treatment
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Application
    • 5.1.1 Arthroscopic Chondroplasty
    • 5.1.2 Autologous Chondrocyte Implantation
    • 5.1.3 Cell-based Cartilage Resurfacing
    • 5.1.4 Osteochondral Grafts Transplantation
    • 5.1.5 Others
  • 5.2 By End User
    • 5.2.1 Hospitals
    • 5.2.2 Ambulatory Surgical Centers
    • 5.2.3 Orthopedic Clinics
  • 5.3 Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Italy
    • 5.3.2.5 Spain
    • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
    • 5.3.3.1 China
    • 5.3.3.2 Japan
    • 5.3.3.3 India
    • 5.3.3.4 Australia
    • 5.3.3.5 South Korea
    • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle-East and Africa
    • 5.3.4.1 GCC
    • 5.3.4.2 South Africa
    • 5.3.4.3 Rest of Middle-East and Africa
    • 5.3.5 South America
    • 5.3.5.1 Brazil
    • 5.3.5.2 Argentina
    • 5.3.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Anika Therapeutics, Inc
    • 6.1.2 Arthrex, Inc
    • 6.1.3 B. Braun Melsungen AG
    • 6.1.4 CartiHeal, Inc
    • 6.1.5 CONMED Corporation
    • 6.1.6 ISTO Technologies, Inc.
    • 6.1.7 Johnson & Johnson (DePuy Synthes)
    • 6.1.8 MEDIPOST Co. Ltd.
    • 6.1.9 Smith & Nephew
    • 6.1.10 Stryker
    • 6.1.11 Vericel Corporation
    • 6.1.12 Zimmer Biomet Holdings, Inc.
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Knee Cartilage Repair Industry Segmentation

As per the scope of the report, cartilage damage is repaired using arthroscopic surgery, which means minimal impact on healthy parts of the knee, less scarring, and quicker recovery times. The report includes both products and therapies. The cartilage may be removed, trimmed, or smoothed down using special tools. The Knee Cartilage Repair Market is Segmented by Application (Arthroscopic Chondroplasty, Autologous Chondrocyte Implantation, Cell-based Cartilage Resurfacing, Osteochondral Grafts Transplantation, and Others), End User (Hospitals, Ambulatory Surgical Centers, and Orthopedic Clinics), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major global regions. The report offers the value (USD million) for the above segments.

By Application Arthroscopic Chondroplasty
Autologous Chondrocyte Implantation
Cell-based Cartilage Resurfacing
Osteochondral Grafts Transplantation
Others
By End User Hospitals
Ambulatory Surgical Centers
Orthopedic Clinics
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle-East and Africa GCC
South Africa
Rest of Middle-East and Africa
South America Brazil
Argentina
Rest of South America
By Application
Arthroscopic Chondroplasty
Autologous Chondrocyte Implantation
Cell-based Cartilage Resurfacing
Osteochondral Grafts Transplantation
Others
By End User
Hospitals
Ambulatory Surgical Centers
Orthopedic Clinics
Geography
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle-East and Africa GCC
South Africa
Rest of Middle-East and Africa
South America Brazil
Argentina
Rest of South America
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Knee Cartilage Repair Market Research FAQs

What is the current Global Knee Cartilage Repair Market size?

The Global Knee Cartilage Repair Market is projected to register a CAGR of 6.2% during the forecast period (2025-2030)

Who are the key players in Global Knee Cartilage Repair Market?

B. Braun Melsungen AG, ISTO Technologies, Inc., Smith & Nephew, Stryker and Zimmer Biomet Holdings, Inc. are the major companies operating in the Global Knee Cartilage Repair Market.

Which is the fastest growing region in Global Knee Cartilage Repair Market?

Asia-Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Global Knee Cartilage Repair Market?

In 2025, the North America accounts for the largest market share in Global Knee Cartilage Repair Market.

What years does this Global Knee Cartilage Repair Market cover?

The report covers the Global Knee Cartilage Repair Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Knee Cartilage Repair Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Global Knee Cartilage Repair Industry Report

Statistics for the 2025 Global Knee Cartilage Repair market share, size and revenue growth rate, created by Mordor Intelligenceā„¢ Industry Reports. Global Knee Cartilage Repair analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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