In Vitro Fertilization Market - Growth, Trends, COVID-19 Impact, and Forecasts (2021 - 2026)

Market Overview

The In Vitro Fertilization Market was valued at approximately USD 685 million in 2020 and is expected to witness a revenue of USD 1,102 million in 2026, with a CAGR of 8.2% over the forecast period.

The impact on COVID-19 pandemic on the studied market is anticipated to be significant as most of the countries across globe have been adopted their own strategies to diminish and eliminate the spread of coronavirus. For instance, the healthcare sectors offering infertility treatments were in inline with the recommendations provided by the WHO. Scientific societies, such as the European Society for Human Reproduction and Embryology and American Society for Reproductive Medicine, have provided recommendations and guidance to overcome and flatten the growing curve of infection in patients who undergo IVF treatments. According to a research article titled “Suspension of fertility treatments during COVID-19 has mental health impacts”, published on Sep 2020, the American Society of Reproductive Medicine and the Canadian Fertility and Andrology Society announced their recommendations to immediately and indefinitely suspend all in-person fertility treatments in the United States and Canada due to COVID-19 from March 17, 2020. As a result, 86 percent of couples amidst treatment reported that treatment suspensions had a negative impact on their mental health and 52 percent reported clinically significant depression symptoms. Also, the recommendations included suspending initiation of new treatments and an alternative freeze-all protocol in cases where couples have already undergone human chorionic gonadotrophin triggering and consideration of cryopreservation of gametes for cases of urgent fertility preservation. Thus, the COVID-19 pandemic is expected to have tremendous impact on the growth of the studied market.

The increasing awareness on advanced In Vitro Fertilization(IVF) techniques, rising success rates of IVF, and disorders due to the delayed onset of pregnancy have stimulated the demand for in vitro fertilization techniques across the world.

The proportion of women who are intentionally delaying pregnancies beyond the age of 35 years has been increasing in the past few years. Delay in pregnancy is a major cause of infertility. Delayed pregnancies, in many cases, lead to pregnancy-associated complications and an increased chance of infertility. According to the Center for Disease Control and Prevention (CDC), about 10 percent of women (6.1 million) in United States aged between 15 -44 have difficulty in getting pregnant or staying pregnant each year. Also, a study by the Hebrew University of Jerusalem revealed that sperm counts for men have more than halved over the last 40 years. As per the UN World Fertility report 2019, the rapid fertility declines were observed in 77 countries globally and areas where adolescent fertility declined by more than 50 per cent between 1990-1995 and 2015-2020.

Furthermore, the growing focus on research and strategic alliances by the key players is driving the market growth. For instance,iIn Jul 2019, Vitrolife signed a collaboration agreement with Prime Tech to develop and exclusively market the Piezo technique for improved Intracytoplasmic sperm injection (ICSI) procedure in human IVF globally except for Japan, Thailand and Malaysia

Moreover, the increasing trend of delayed pregnancy is contributing to the higher adoption of IVF techniques. However, the complications associated with the IVF technique and socio-ethical issues involved are expected to restrict the growth of the market studied, over the forecast period.

Scope of the Report

In Vitro Fertilization is an Assistive Reproductive Technology, which involves the process of fertilization by retrieving eggs from the woman's ovaries and fertilizing them with sperm outside the body, under a laboratory environment. The in vitro fertilization market is segmented by products, end-user, and geography. By products, the market is segmented into reagents, and instruments (imaging systems, incubators, cryosystems, IVF cabinet, ovum aspiration pump, sperm separation systems, micromanipulator systems, and other instruments). By end-user, the market is segmented into fertility clinics, hospitals, and other end users. By Geography, the market is segmented into North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The report offers the value (in USD million) for the above segments.

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Key Market Trends

The Sperm Separation Systems Segment is Estimated to Hold the Largest Share in Terms of Revenue Generated over the Forecast Period

Sperm Separation Systems are used in most Assisted reproductive technology (ART) such as in In vitro fertilization (IVF) and artificial insemination. These systems are crucial for ARTs as they provide purified samples for further procedures. Furthermore, the rising focus of companies on developing novel devices for use in assisted reproductive technology (ART) procedures conducted by fertility clinics and obstetrician-gynecologist (OB/GYN) practices is driving the market growth. For instance, in March 2018, DxNow, Inc., received US FDA 510(k) clearance of its ZyMōt ICSI and ZyMōt Multi Sperm Separation Devices. The devices are used in the separation and preparation of highly-motile sperm with normal morphology and thus aid in assisted reproductive technology procedures. The ZyMōt Multi (provided with 850µl and 3ml collection chambers) has an inlet port that communicates with the lower sample chamber. The sample chambers are separated by a microporous filter. Untreated semen is added through the inlet port and after a period of time, the separated sperm are collected from the upper chamber through the outlet port.

Healthier sperm produce outcomes, such as improved progressive motility, a higher proportion of normal morphology, increased fertilization rates, and higher euploidy and pregnancy rates. The improved outcome associated with these devices may fuel its demand in the future.

Additionally, as per the research article published in BioRXiV, 2020, a new microchamber-based microfluidics platform was studied to separate only the progressively motile sperm directly from a raw semen sample in a short period of time of approximately 10 minutes. Hence owing to the recent advancements and novel product launches, the market is expected to grow at a healthy CAGR over the forecast period.

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