| Study Period | 2019 - 2030 |
| Base Year For Estimation | 2024 |
| Market Size (2025) | USD 612.58 Million |
| Market Size (2030) | USD 786.30 Million |
| CAGR (2025 - 2030) | 5.12 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Immunoprecipitation Testing Market Analysis
The Global Immunoprecipitation Testing Market size is estimated at USD 612.58 million in 2025, and is expected to reach USD 786.30 million by 2030, at a CAGR of 5.12% during the forecast period (2025-2030).
The COVID-19 pandemic is expected to have a significant impact on the growth of the studied market. The coronavirus enters the cell when viral spike protein binds to the ACE2 protein present on the surface of human cells. Immunity among the COVID-19 recovered patients is predicted to develop due to the presence of neutralizing antibodies that block this binding. Hence, researchers study the protein interactions and action of neutralizing antibodies. For instance, as per the research study published in Science Daily in December 2020, titled 'Plasma From Recovered COVID-19 Patients Inhibits Spike Protein Binding to ACE2 in a Microsphere-Based Inhibition Assay', researchers applied immunoprecipitation associated with flow cytometry (IP-FCM) in studying the interactions of proteins in SARS-CoV2 infection and the role of antibodies in blocking the virus from binding to cells. Thus, given the ongoing pandemic and increasing research activities, the studied market is expected to be significantly impacted by the current crisis.
The immunoprecipitation testing market is increasing due to the prevalence of autoimmune disorders, which require antibody-antigen interaction testing. Additionally, the growing opportunities in funding and investments from the government and non-government organizations toward the research on next-generation DNA sequencing and genomics are fueling the market growth. In February 2021, the National Institute of Allergy and Infectious Diseases (NIAID) initiated a Phase 1 clinical study to evaluate the safety and immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine, in which the secondary immunogenicity endpoints are measured using luciferase immunoprecipitation assay.
The growing applications of immunoprecipitation testing in central nervous disorders, cancers, and cardiovascular diseases are also boosting the growth of the immunoprecipitation testing market. The tumor cells resistant to drugs exhibit dynamic protein-protein interactions; immunoprecipitation testing aids in studying these interactions among cancer patients. According to the Globocan 2020 fact sheet, an estimated 19,292,789 new cancer cases were diagnosed worldwide, with nearly 9,958,133 deaths from cancer globally. According to estimates from the International Agency for Research on Cancer (IARC), by 2040, the global burden of cancers is expected to grow to 27.5 million new cancer cases and 16.3 million deaths worldwide. Thus, the growing burden of cancers is also expected to drive market growth.
Additionally, in May 2019, Merck & Co. Inc. established a new life science facility that is majorly aimed at research and development activities related to oncology, immunology, and immuno-oncology.
However, limitations in sample size and variations in lipid content might hamper the wide application of this test, which is expected to impede the market growth.
Immunoprecipitation Testing Market Trends
Chromatin Immunoprecipitation (ChIP) is Expected to Dominate the Market by Type Over the Forecast Period
Chromatin immunoprecipitation (ChIP) is a type of immunoprecipitation technique used to investigate the regions of the genome associated with target DNA-binding protein, or to identify the specific proteins associated with a specific region of the genome. Chromatin immunoprecipitation is commonly used in epigenetics research.
ChIP is expected to experience significant growth owing to technological advances. For instance, the Chromatrap technology enables data accuracy and delivers quick results without any pipetting risks, allowing researchers to simultaneously analyze multiple antibodies and gene targets.
In the current COVID-19 pandemic, ChIP plays a vital role in determining the protein-DNA interactions, which is very important in understanding the target binding sequences for the SARS-Cov2 Virus. Thus, as the research progresses, the studied segment is expected to witness significant growth during the pandemic.
Additionally, the key players are involved in research activities to develop improved protocols for chromatin immunoprecipitation, which aids in the growth of the studied market. For instance, in the study published in Bio-Protocol in December 2020, titled 'Chromatin Immunoprecipitation (ChIP) to Assess Histone Marks in Auxin-treated Arabidopsis thaliana Inflorescence Tissue' chromatin immunoprecipitation, coupled with quantitative PCR (Chip-qPCR), was used in the identification of binding sites of DNA binding proteins and the detection of histone modification on locus-specific areas of the genome. Hence, the extensive application of ChIP in various genomic studies is a major factor driving the studied segment over the forecast period.
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North America Holds the Major Share in Immunoprecipitation Testing Market and is Expected to Dominate the Market Over the Forecast Period
North America holds the major share in the immunoprecipitation testing market owing to the increasing investments and government funding, especially in biotechnology research, and growing awareness regarding personalized medicine. Additionally, growing collaborations and partnerships between organizations and universities and a high concentration of key regional players are expected to drive the studied market in the region. Various government bodies, like NHGRI (National Human Genome Research Institute), have supported the work on sequencing of the human genome and funded the research that involves the study of the genome's structure, function, and role in human health and various disease.
In April 2020, GlaxoSmithKline invested USD 250 million in Vir Biotechnologies, a San Francisco-based clinical-stage immunology company, to support its antibody-drug development program for COVID-19. Similarly, in April 2020, the federal government granted USD 14.5 million to Emergent BioSolutions-a Maryland-based biopharmaceutical company-to working on an antibody-drug trial for COVID-19. However, this pandemic has slowed the discovery and development activities of biological products for other applications, such as oncology and rare diseases, which may somewhat hamper growth.
With the growing number of COVID-19 cases in the region, particularly in the United States, extensive research employs advanced tools such as immunoprecipitation sequencing to study the DNA-protein interactions and genome analysis. Additionally, according to the research article published by the National Institutes of Health (NIH) in June 2020, titled 'Increasing Prevalence of Antinuclear Antibodies in the United States' the prevalence of antinuclear antibodies (ANA), which is the common biomarker of autoimmunity, was significantly increasing in the United States over the years. Thus, given the aforementioned factors, the North American region is expected to witness significant growth over the forecast period.
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Immunoprecipitation Testing Industry Overview
The immunoprecipitation testing market has rapidly evolved over the last few years. In recent years, the major players in the studied market are expanding their product portfolio through strategies such as product developments, mergers, and acquisitions. Thus, the immunoprecipitation testing market has become a moderately competitive industry. The major players in the studied market include Merck KGaA, Thermo Fisher Scientific, Inc., Bio-rad laboratories, GenScript Biotech Corporation, and Biologics International Corp, among others.
Immunoprecipitation Testing Market Leaders
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Bio-Rad Laboratories
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Biologics International Corp
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Merck KGaA
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Thermo Fisher Scientific, Inc.
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GenScript Biotech Corporation
- *Disclaimer: Major Players sorted in no particular order
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Immunoprecipitation Testing Market News
In March 2022, T2T Consortium published early findings from complete human genome assembly. Researchers outlined the genome sequence, genetic variant, epigenetic, expression, and other insights being gleaned from a complete "telomere-to-telomere" (T2T) version of the human reference genome.
In February 2022, MilliporeSigma, through its Sigma-Aldrich business, licensed its portfolio of CRISPR-related intellectual property to Israeli agbio firm BetterSeeds for use in plants.
Immunoprecipitation Testing Industry Segmentation
As per the scope of this report, immunoprecipitation (IP) is a precipitation procedure that purifies and enriches the selected protein by allowing the identification of protein-protein interactions in proteomics workflows. Immunoprecipitation is one of the major tools used in identifying the presence and size of proteins and studying downregulation or up-regulation, relative abundance, post-translational modifications (PTMs), stability, and interactions between proteins. The immunoprecipitation testing market is segmented by Type (Individual Protein Immunoprecipitation, Co-immunoprecipitation (Co-IP), Chromatin Immunoprecipitation (ChIP), RNA Immunoprecipitation (RIP), and Other Types), End User (Pharmaceutical and Biotechnology Industries, Contract Research Organizations (CROs), and Academic and Research Institutes), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major global regions. The report offers the value (in USD million) for the above segments.
| By Type | Individual protein immunoprecipitation | ||
| Co-Immunoprecipitation (Co-IP) | |||
| Chromatin Immunoprecipitation (ChIP) | |||
| RNA Immunoprecipitation (RIP) | |||
| Other Types | |||
| By End User | Pharmaceutical and Biotechnology Industries | ||
| Contract Research Organizations (CRO's) | |||
| Academic and Research Institutes | |||
| Geography | North America | United States | |
| Canada | |||
| Mexico | |||
| Europe | Germany | ||
| United Kingdom | |||
| France | |||
| Italy | |||
| Spain | |||
| Rest of Europe | |||
| Asia-Pacific | China | ||
| Japan | |||
| India | |||
| Australia | |||
| South Korea | |||
| Rest of Asia-Pacific | |||
| Middle-East and Africa | GCC | ||
| South Africa | |||
| Rest of Middle-East and Africa | |||
| South America | Brazil | ||
| Argentina | |||
| Rest of South America | |||
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Immunoprecipitation Testing Market Research FAQs
How big is the Global Immunoprecipitation Testing Market?
The Global Immunoprecipitation Testing Market size is expected to reach USD 612.58 million in 2025 and grow at a CAGR of 5.12% to reach USD 786.30 million by 2030.
What is the current Global Immunoprecipitation Testing Market size?
In 2025, the Global Immunoprecipitation Testing Market size is expected to reach USD 612.58 million.
Who are the key players in Global Immunoprecipitation Testing Market?
Bio-Rad Laboratories, Biologics International Corp, Merck KGaA, Thermo Fisher Scientific, Inc. and GenScript Biotech Corporation are the major companies operating in the Global Immunoprecipitation Testing Market.
Which is the fastest growing region in Global Immunoprecipitation Testing Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).
Which region has the biggest share in Global Immunoprecipitation Testing Market?
In 2025, the North America accounts for the largest market share in Global Immunoprecipitation Testing Market.
What years does this Global Immunoprecipitation Testing Market cover, and what was the market size in 2024?
In 2024, the Global Immunoprecipitation Testing Market size was estimated at USD 581.22 million. The report covers the Global Immunoprecipitation Testing Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Global Immunoprecipitation Testing Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
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Global Immunoprecipitation Testing Industry Report
Statistics for the 2025 Global Immunoprecipitation Testing market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Global Immunoprecipitation Testing analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
