Protein Expression Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

Market Overview

The Protein Expression Market is expected to register a CAGR of 11.33% during the forecast period with a revenue of USD 2,047.91 million in 2020, and it is expected to reach USD 3,718.34 million by 2026.

The market has a slightly positive impact due to the pandemic. The development of therapeutic and preventive strategies requires an accurate understanding of the role that proteins play in the SARS-CoV-2 infection process and progression of COVID-19. The vast field of proteomics is well equipped with the technologies needed to help in facing this challenge. In an article published in October 2020 in the Journal of Proteins and Proteomics, researchers have highlighted that developments in proteome technologies will not only accelerate progress in addressing the coronavirus pandemics but could also prove invaluable in tackling the current COVID-19 crisis.

The propelling factors for the growth of the protein expression market include the rise in the R&D activity in the pharmaceutical sector, opportunities in the field of proteomics, advancements in the biologics market set to boost the market growth, and increasing incidences of chronic diseases. As per the World Health Organization 2020, the major chronic diseases such as cardiovascular diseases (CVD), cancer, chronic obstructive pulmonary disease and type 2 diabetes are estimated to account to 73% of all deaths and 60% of the global burden of diseases in 2020.

Biologics have played a crucial role in the treatment process of many health issues. The success of Humira, a drug for the treatment of rheumatoid arthritis, has been an encouraging factor for many drug makers to continue working in the pathway of biologics. The growing demand for biologicals increase the prospects of its manufacturing using the protein expression systmens boosting the market growth.

In addition the biotechnology-based organizations have also created a big opportunity for the protein expression market growth by developing novel therapeutics with minimal side effects. The increasing research intensity in the pharmaceutical sector is adding up to the opportunities for growth.

Therefore at present, the protein expression market is a highly attractive and profitable market due to the increasing adoption of biotechnology as well as genetic engineering in the pharmaceutical industry and medical science. However, the high cost of protein expression systems and lack of effective systems for post-translational modifications are expected to restrain the market growth over the forecast period.

Scope of the Report

As per the scope of the report, protein expression is the way in which proteins are modified, synthesized, and regulated in living organisms. The term is applicable to either the object of study or the laboratory techniques required to manufacture proteins. Proteins are regulated and synthesized depending upon the functional need in the host cell. The translation, transcription, and post-translational modifications are the three processes involved in protein expression. The protein expression market is Segmented By Product (Reagent and Kits, Service, Other Products), By Application (Therapeutic, Industrial, Research), By End User (Academia, Biotechnology & Pharmaceuticals Companies, Contract Research Organizations (CROs),)and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.

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Key Market Trends

Cell Free Expression is Expected to Hold a Major Market Share in the Protein Expression Market

The cell-free protein expression is well-established in the market, due to the acceptance of it and this protein expression is performed without the use of living cells. This technique has many advantages over other protein expression techniques and because of its advantages, it is widely used. Due to the advantages of cell-free protein techniques, such as increased speed, ability to express toxic proteins, ease of amino acid type selective labeling, among others, these are making the cell expression market grow.

Furthermore, the growing launches of cell-free systems boost the usage of the kits and reagents. For instance, in 2019, Arbor Biosciences announced the launch of myTXTLTM bulk offerings of cell-free expression systems. These new offerings align with the growing demand for larger volume requirements by organizations utilizing high-throughput screening in protein and enzyme engineering. These cell-free expression systems are currently available from Arbor Biosciences as a Sigma 70 or a linear DNA expression master mix

Moreover, the growing research and studies on cell-free systems, especially due to COVID is further boosting the growth of the segment. The article ‘Combating COVID-19 with Cell-Free Expression’ published in October 2020, synthetic biologists pivoted the cell-free expression technology that they were using for other diseases to develop new diagnostics, materials, and treatments specifically for COVID-19.

Therefore, the unique technology may increase the growth of the cell-free expression market, which in turn, is expected to boost the protein expression market.

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