Protein Expression Market - Growth, Trends, COVID-19 Impact, and Forecasts (2021 - 2026)

The protein expression market is Segmented By Product (Instrument, Reagent, Service, Other Products), By Expression System, By End User and Geography.

Market Snapshot

protein expression market
Study Period:

2018 - 2026

Base Year:


Fastest Growing Market:

Asia Pacific

Largest Market:

North America


5.1 %

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Market Overview

The Protein Expression Market is expected to register a CAGR of 5.1% during the forecast period. The propelling factors for the growth of the protein expression market include the rise in the R&D activity in the pharmaceutical sector, opportunities in the field of proteomics, advancements in the biologics market set to boost the market growth, and increasing incidences of chronic diseases. According to the World Health Organization (WHO), in the year 2018, worldwide estimated 18.1 million new cases of cancer and approximately 9.6 million deaths. In addition, one in 5 men and one in 6 women globally develop cancer during their lifetime, and one in 8 men and one in 11 women die from the disease.

Biologics have played a crucial role in the treatment process of many health issues. The success of Humira, a drug for the treatment of rheumatoid arthritis, has been an encouraging factor for many drug makers to continue working in the pathway of biologics. Therefore, it is expected that the biologics industry may grow exponentially in the future. This is attributed to the fact that biologics are counted upon to deliver cures through gene therapy using viruses. Therefore, similar technological advances are thus expected to boost the growth of the biologics market.

In addition the biotechnology-based organizations have also created a big opportunity for the protein expression market growth by developing novel therapeutics with minimal side effects. The increasing research intensity in the pharmaceutical sector is adding up to the opportunities for growth.

Therefore at present, the protein expression market is a highly attractive and profitable market due to the increasing adoption of biotechnology as well as genetic engineering in the pharmaceutical industry and medical science.

Scope of the Report

As per the scope of the report, protein expression is the way in which proteins are modified, synthesized, and regulated in living organisms. The term is applicable to either the object of study or the laboratory techniques required to manufacture proteins. Proteins are regulated and synthesized depending upon the functional need in the host cell. The translation, transcription, and post-translational modifications are the three processes involved in protein expression. The Protein Expression Market is segmented by product, expression system, end user and geography.

By Expression System
Cell-Free Expression
Bacterial Expression
Yeast Expression
Algal Expression
Insect Expression
Mammalian Expression
Other Expression Systems
By Product
Other Products
By End User
Academic and Research Institutes
Pharmaceuticals and Biotechnology Industries
Other End Users
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East & Africa
South Africa
Rest of Middle-East & Africa
South America
Rest of South America

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Key Market Trends

Cell Free Expression is Expected to Hold a Major Market Share in the Protein Expression Market

The cell-free protein expression is well-established in the market, due to the acceptance of it and this protein expression is performed without the use of living cells. This technique has many advantages over other protein expression techniques and because of its advantages, it is widely used. Due to the advantages of cell-free protein techniques, such as increased speed, ability to express toxic proteins, ease of amino acid type selective labelling, among others, these are making the cell expression market to grow.

According to the International Agency for Research on Cancer (IARC), by the year 2040, it is estimated that new cases of cancer to grow to 27.5 million. In addition, the global cancer burden is anticipated to increase by 70% in the next 20 years.

Therefore, the unique technology may increase the growth of the cell-free expression market, which in turn, is expected to boost the protein expression market.

protein key trend 1.png

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North America is the Largest Growing Market that is Expected to Continue the Same Trend Over the Forecast Period

North America is the largest market for protein expression and is expected to dominate the overall protein expression market due to factors like the presence of well-established healthcare infrastructure in these regions combined with the intense R&D activities carried out. The United States protein expression market is driven by factors, such as an increase in the usage of protein technologies, the rapid evolution of the pharmaceutical industry in the region, and the presence of several companies in the region itself. According to the Centers for Disease Control and Prevention, in the year 2017, coronary heart disease is the most common type of heart disease, killing approximately 365,914 people in the United States. Moreover, about 18.2 million adults age 20 and older have Coronary heart disease (CAD), 2 in 10 deaths from Coronary heart disease happen in adults less than 65 years old. Thus, owing to the above factors the market is expected to grow in this country.

Protein Expression Market2

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Competitive Landscape

The Protein Expression Market is fragmented competitive. The companies present have a broad product portfolio with comprehensive features and have a strong geographical presence. Furthermore, these leaders cater to the requirements of major end users, such as research laboratories and pharmaceutical and biotechnology companies. Some of the companies which are currently dominating the market are Agilent Technologies Inc., Bio-Rad Technologies, Thermo Fisher Scientific Inc., Merck KGA, Takara Bio Inc., New England Biolabs Inc., Oxford Expression Technologies Ltd, Promega Corporation, Qiagen NV, and Sigma-Aldrich Corporation.

Table of Contents


    1. 1.1 Study Deliverables

    2. 1.2 Study Assumptions

    3. 1.3 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Rising R&D Activity in the Pharmaceutical Sector

      2. 4.2.2 Escalation in the Biologics Market

      3. 4.2.3 Increasing Incidences of Chronic Diseases

    3. 4.3 Market Restraints

      1. 4.3.1 High Cost of Protein Expression Systems

      2. 4.3.2 Growing Competition Among the Vendors

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Expression System

      1. 5.1.1 Cell-Free Expression

      2. 5.1.2 Bacterial Expression

      3. 5.1.3 Yeast Expression

      4. 5.1.4 Algal Expression

      5. 5.1.5 Insect Expression

      6. 5.1.6 Mammalian Expression

      7. 5.1.7 Other Expression Systems

    2. 5.2 By Product

      1. 5.2.1 Instrument

      2. 5.2.2 Reagent

      3. 5.2.3 Service

      4. 5.2.4 Other Products

    3. 5.3 By End User

      1. 5.3.1 Academic and Research Institutes

      2. 5.3.2 Pharmaceuticals and Biotechnology Industries

      3. 5.3.3 Other End Users

    4. 5.4 Geography

      1. 5.4.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.4.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.4.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.4.4 Middle-East & Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East & Africa

      5. 5.4.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Agilent Technologies Inc.

      2. 6.1.2 Bio-Rad Technologies

      3. 6.1.3 Merck KGaA

      4. 6.1.4 Takara Bio Inc.

      5. 6.1.5 New England Biolabs Inc.

      6. 6.1.6 Oxford Expression Technologies Ltd

      7. 6.1.7 Promega Corporation

      8. 6.1.8 Qiagen NV

      9. 6.1.9 Creative Biolabs

      10. 6.1.10 Thermo Fisher Scientific Inc.

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments

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Frequently Asked Questions

The Protein Expression Market market is studied from 2018 - 2026.

The Protein Expression Market is growing at a CAGR of 5.1% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

  • Agilent Technologies Inc
  • Thermo Fisher Scientific Inc
  • Merck KGaA
  • Takara Bio Inc
  • New England Biolabs Inc

Are the major companies operating in Protein Expression Market.

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