Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market Size and Share

Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market Analysis by Mordor Intelligence
The Europe Insulin Drugs And Glucagon-Like Peptide 1 Receptor Agonist market size is expected to grow from USD 10.06 billion in 2025 to USD 10.49 billion in 2026 and is forecast to reach USD 12.93 billion by 2031 at 4.27% CAGR over 2026-2031.
The COVID-19 epidemic has significantly affected the market for insulin drugs and devices. Patients with type-1 diabetes are more affected by COVID-19. Since people with diabetes already have weakened immune systems, COVID-19 causes those immune systems to deteriorate rapidly. Those with diabetes are more likely to experience significant complications than healthy persons. During COVID-19, the manufacturers of insulin drugs worked with local governments to provide insulin drugs to diabetes patients.
NovoNordisk stated on their website that 'Since the start of COVID-19, our commitment to patients, our employees and the communities where we operate has remained unchanged, we continue to supply our medicines and devices to people living with diabetes and other serious chronic diseases, safeguard the health of our employees, and take actions to support doctors and nurses as they work to defeat COVID-19.' Doctors around the world suggested diabetes patients check their diabetes levels more often to be careful and the intake of medicine has increased, which lead to an increase in the usage of insulin drugs.
The rates of newly diagnosed Type 1 and Type 2 diabetes cases are seen increasing among the youth in Europe. The prevalence of diabetes among all ages in the European region is increasing, mainly due to obesity, unhealthy diet, and physical inactivity. The prevalence of autoimmune Type 1 diabetes is also increasing in Europe, and as per sources, Europe has the highest number of children with Type 1 diabetes. Though Type 2 patients are initiated with oral drugs, insulin may also be required when glucose levels are not well controlled due to an unhealthy lifestyle. Thus, the demand for insulin also exists among Type 2 diabetes patients.
Each drug is unique in the way it works in helping patients with diabetes to keep their condition under control. Certain drugs have similar actions, and they are grouped in the same class. They can also be classified in the way they are administered, with some medicines taken orally and others injected directly into the blood (insulin and GLP-1).
Byetta was the first GLP-1 that received approval in 2005. The glucagon-like peptide receptor agonist is administered subcutaneously and is used by Type 2 diabetes patients to control their blood glucose levels.
The rapidly increasing incidence and prevalence of diabetic patients and healthcare expenditure in Europe are indications of the increasing usage of diabetic drug products. Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period.
Note: Market size and forecast figures in this report are generated using Mordor Intelligence’s proprietary estimation framework, updated with the latest available data and insights as of 2026.
Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market Trends and Insights
The rise in Insulin Drug Pricing in Europe
Insulins have been in the market for decades. However, the cost of insulin has always been a primary concern. A recent example is the pull-out of Tresiba from Germany due to the pricing pressure after the authorities said they would price the long-acting basal insulin on par with old human insulin injections. Though biosimilar competition in Europe increased, allowing insulin prices to be low, branded drugs have always been the order of the day. Moreover, leading players have gotten multiple extensions by making incremental improvements to their branded drugs. In recent years, diabetes prevalence has increased alarmingly throughout the European continent. People with diabetes must make several adjustments daily to keep their blood glucose levels within acceptable ranges. Examples include taking oral anti-diabetic medicine or consuming more carbs while monitoring their blood glucose levels. Obesity, a poor diet, and lack of exercise are the main causes of the rise in newly diagnosed Type 1 and Type 2 diabetes cases. Diabetes medicine usage is on the rise, as evidenced by the fast-rising incidence, prevalence, and healthcare costs of diabetes individuals. R&D of diabetes is crucial from many perspectives. Around 10% of all healthcare costs in Italy are related to diabetes. Diabetes represents a major public health challenge in Italy. R&D of diabetes is extensive across the world and in Italy itself. Italy ranks 3rd globally in the peer-reviewed publication of research on endocrine-metabolic topics. However, the incidence of diabetes is increasing due to lifestyle and nutrition factors.
Despite the increasing insulin drug prices, with the increasing type-1 population in Europe, the market for insulin drugs is increasing, and there is no alternative.

Germany Held the Highest Market Share in Current Year
In current year, Germany dominated the insulin market and is expected to continue its dominance during the forecast period. The rise is due to the high prevalence of diabetes among the country's population. In Germany, according to an estimate, the number of patients with Type 1 and Type 2 diabetes is gradually increasing. Pharmaceutical manufacturers in the country, including Novo Nordisk, have assured diabetes patients that there is no current impact of COVID-19 on their supply chain. Furthermore, companies regularly monitor their supply chain to assess the situation better and act proactively to ensure minimal or no disruption in the availability of insulin drugs for the diabetes population in the country. Insulin drug pricing is a major concern in many countries, and Germany is no exception. The German government regulates the prices of drugs; thus, pharmaceutical companies focus on pricing the products at minimal rates.
Over the next twenty years, type 2 diabetes will become more prevalent in Germany. By 2040, up to twelve million people could have the metabolic disorder, according to DZD researchers. The rapid rise in type 1 and type 2 diabetes among the aging population will present significant issues for the German Diabetes Medications system in the years to come. The German Diabetes Center (DDZ) estimates that at least 7.2% of the population in Germany presently has diabetes, and that number will rise dramatically over the next 20 years. Obesity, a poor diet, and lack of exercise are the main causes of the rise in newly diagnosed Type 1 and Type 2 diabetes cases. Healthcare spending and the fast-rising incidence and prevalence of diabetic individuals are signs of market expansion. A cap on out-of-pocket medical expenses and coverage of all medically required treatments, including insulin medications, are mandated by German law for public insurance plans. T1 International, an organization that advocates for individuals with diabetes, claims that out-of-pocket expenses for German diabetes patients are among the lowest globally. In Germany, strict government rules and supportive WHO regulations incentivize businesses to create novel products. These solutions' market penetration in Germany helps regional clinical research organizations (CROs) with their clinical research trials and assures managerial simplicity, which speeds up the discovery process.
As a result, the studied market is expected to develop throughout the analysis period due to the rising prevalence of diabetes.

Competitive Landscape
The Europe Insulin Drugs and GLP-1 receptor agonist market is largely consolidated in nature, with the presence of leading companies like Sanofi, Novo Nordisk, and Eli Lilly. They account for more than 80% of the supply in Europe. All these companies have established their brands in the market. However, due to intense competition in the local markets for insulin, consumer penetration for their products must be achieved through constant work and effort.
Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Industry Leaders
Sanofi
Eli Lilly
Novo Nordisk
AstraZeneca
Biocon
- *Disclaimer: Major Players sorted in no particular order

Market Opportunities and Future Outlook
Reimbursement updates and route-of-administration changes are widening treatment access for GLP-1 portfolios alongside continued insulin use across Europe. In 2026, France confirmed national health insurance coverage for Wegovy and Mounjaro effective 15 June 2026, with defined reimbursement and eligibility criteria. In parallel, the EU authorized an oral Wegovy tablet and a higher-dose 7.2 mg pen in July 2026.
These decisions give manufacturers more concrete options when designing country-level access strategies across differing HTA processes and public-budget structures. On the supply side, Novo Nordisk's EUR 400 million expansion of its oral GLP-1 tabletting facility in Athlone, Ireland (March 2026) and its inauguration of a new manufacturing facility in Bohumil, Czech Republic for APIs for its diabetes and obesity portfolio (June 2026) indicate capacity and localization initiatives aimed at maintaining continuity for high-volume peptide products. Portfolio rationalization and lifecycle changes in insulin, including discontinuations of certain legacy insulin presentations reported in 2026, also create room for differentiated delivery approaches and for competition in selected insulin categories, within national reimbursement rules and prescribing pathways.
Recent Industry Developments
- July 2026: The European Commission granted marketing authorization for Novo Nordisk's Wegovy pill (oral semaglutide) for weight management, and also authorized a higher-dose 7.2 mg injection pen. The development expands format options for prescribers and influences how companies position GLP-1 therapies as countries adjust access pathways for obesity and related metabolic disease management.
- June 2026: Novo Nordisk inaugurated a new manufacturing facility in Bohumil, Czech Republic focused on APIs for its diabetes and obesity portfolio. The facility increases local API production capacity and supports EU supply continuity.
- March 2026: Novo Nordisk announced an over EUR 400 million expansion of its oral GLP-1 tabletting facility in Athlone, Ireland. The expansion strengthens European manufacturing capacity for oral semaglutide and supports planned demand growth.
Research Methodology Framework and Report Scope
Market Definition and Coverage
For this report, we define the market as the sales value of prescription insulin drugs and GLP-1 receptor agonist therapies used for diabetes care across Europe, counted at the manufacturer level and converted into USD using consistent year-average exchange rates.
Scope exclusions: We exclude insulin delivery devices, glucose monitoring products, and non-GLP-1 diabetes drug classes (such as SGLT-2 inhibitors and DPP-4 inhibitors).
Segmentation Overview
- GLP-1 Receptor Agonists
- Exenatide
- Byetta
- Bydureon
- Liraglutide (Victoza)
- Lixisenatide (Lyxumia)
- Dulaglutide (Trulicity)
- Semaglutide (Ozempic)
- Exenatide
- Insulin Drugs
- Basal or Long-acting Insulins
- Lantus (Insulin glargine)
- Levemir (Insulin detemir)
- Toujeo (Insulin glargine)
- Tresiba (Insulin degludec)
- Basaglar (Insulin glargine)
- Bolus or Fast-acting Insulins
- NovoRapid/Novolog (Insulin aspart)
- Humalog (Insulin lispro)
- Apidra (Insulin glulisine)
- FIASP (Insulin aspart)
- Admelog (Insulin lispro)
- Traditional Human Insulins
- Novolin/Actrapid/Insulatard
- Humulin
- Insuman
- Combination Insulins
- NovoMix (Biphasic Insulin aspart)
- Ryzodeg (Insulin degludec/Insulin aspart)
- Xultophy (Insulin degludec/Liraglutide)
- Soliqua/Suliqua (Insulin glargine/ Lixisenatide)
- Biosimilar Insulins
- Insulin Glargine Biosimilars
- Human Insulin Biosimilars
- Basal or Long-acting Insulins
- Geography
- United Kingdom
- Germany
- France
- Italy
- Spain
- Russia
- Rest of Europe
Data Sources, Market Sizing, and Validation
Desk Research
Desk work starts with building the demand and access context, since diabetes treatment use is shaped by epidemiology and reimbursement pathways. We review public health statistics and clinical guidance, such as World Health Organization diabetes indicators, OECD health data, and European Medicines Agency labels and safety updates, which clarify what is approved and how it is used in practice.
To anchor country-level inputs, we also reference sources such as Eurostat demographic tables and health expenditure series, alongside national health system publications and payer updates where they are publicly available. For pricing and utilization context, we cross-check tender and procurement signals, published reimbursement decisions, and company filings and investor materials. Paid subscriptions are used selectively for standardized company financials and for patent and innovation checks where it helps validate product lifecycle timing. These examples are illustrative, and many other public sources are reviewed during data collection, cross-checks, and clarification.
Primary Interviews and Surveys
Primary work is used to translate the desk view into workable assumptions for how insulin and GLP-1 therapies are prescribed and reimbursed across European countries. We speak with a mix of clinicians, hospital and retail pharmacy stakeholders, payer or formulary informed experts, and supply-side commercial roles to confirm therapy-mix shifts, access restrictions, and typical price evolution.
Because Europe is not a uniform market, we ensure coverage across major Western European systems and selected Central and Eastern markets, and then we re-check gaps where a single country can move totals through a policy change or a shortage event.
Distribution of primary research fieldwork respondents
| Company type | Respondent position | Region |
|---|---|---|
| Top tier: 39% | CXOs: 21% | |
| Mid tier: 40% | Functional/Unit leaders: 34% | |
| Smaller Players: 21% | Managers: 45% |
Market-Sizing & Forecasting
Sizing is built from a top-down treated-patient and therapy adoption view, where diabetes prevalence and diagnosis rates are translated into treated cohorts, which are then mapped to insulin versus GLP-1 usage patterns by country. The core model is corroborated with selective bottom-up checks using supplier revenue splits, channel feedback, and sampled price per patient or price per pack multiplied by estimated volumes, and adjustments are made when the two views do not reconcile.
Key inputs used to shape the totals include diabetes prevalence and age mix, intensity of insulin use in advanced type 2 and type 1 treatment, GLP-1 uptake linked to guideline positioning and obesity overlap, formulary access and reimbursement criteria, switching from older human insulin to analogs and biosimilars, and country-level price erosion versus volume growth. Where direct volume signals are not available, gaps are handled using proxy logic, such as peer-country benchmarks with similar reimbursement structures and validated treatment rates, then reviewed again with interview feedback.
For forecasting, we rely on scenario analysis supported by trend lines in access expansion, pipeline and launch timing, and expected price movements, stress-tested country by country. Assumptions are kept simple and auditable so that a reader can reproduce the steps using the same public indicators and a small set of validated interview inputs.
Data Validation & Update Cycle
Outputs are validated through a set of cross-checks that look for mismatches against independent signals, such as diabetes population trends, therapy class share shifts discussed by experts, and country reimbursement changes that should visibly affect demand. When an outlier appears, it is investigated through input review, re-running sensitivity on key assumptions, and re-contacting relevant respondents if the variance cannot be explained.
Before sign-off, the model and written conclusions go through multi-step analyst review so that definitions, currency timing, and country additions are consistent throughout. Reports are refreshed annually, and interim updates are triggered when a material event occurs, such as a major label change, reimbursement expansion, or a supply disruption. Right before delivery, a final pass is completed to ensure the latest public updates are reflected in the numbers.
Mordor Intelligence's Europe Insulin Drugs and Glucagon Like Peptide 1 Receptor Agaonist Market Size Compared With Other Published Estimates
Published market sizes for this space often look different because authors draw the line around therapy classes in different ways and apply different price and access assumptions across Europe. Even when the same countries are covered, totals can shift based on whether the estimate reflects list prices versus net prices, and whether short-term shortage and substitution effects are treated as one-off or structural.
Key gaps usually come from what is counted as in-scope therapy revenue and how quickly GLP-1 uptake is assumed to expand across obesity-linked use. Another common driver is the handling of biosimilars and fixed-dose combinations, where some estimates either double count across classes or exclude combination value to avoid overlap, and currency conversion timing can add another layer of spread.
Benchmark comparison
| Source | Market Size | Gaps in Research Methodology |
|---|---|---|
| Mordor Intelligence | USD 10.06 B (2025) | |
| Industry Association A | USD 9.10 B (2024) | Uses a diabetes drug spend lens that can understate newer GLP-1 growth by mixing hospital and retail reporting cycles and by not separating combination therapies consistently across countries. |
| Regional Consultancy B | USD 12.00 B (2025) | Often applies a faster GLP-1 penetration curve across Europe and leans on list-price style assumptions, which can inflate value where reimbursement discounts and eligibility limits are tighter. |
The table shows a spread that mainly tracks what is included under the therapy boundary and how quickly pricing is assumed to normalize across countries. In Mordor Intelligence's model, the value includes insulin drugs and GLP-1 receptor agonists with biosimilars and fixed-dose combinations counted once under the therapy revenue pool. With that scope kept consistent across the covered European countries, the final number stays traceable to treated cohorts, access signals, and a small set of clearly stated price and mix assumptions.
Key Questions Answered in the Report
How big is the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market?
The Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market size is expected to reach USD 10.49 billion in 2026 and grow at a CAGR of 4.27% to reach USD 12.93 billion by 2031.
What is the current Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market size?
In 2026, the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market size is expected to reach USD 10.49 billion.
Who are the key players in Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market?
Sanofi, Eli Lilly, Novo Nordisk, AstraZeneca and Biocon are the major companies operating in the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market.
What years does this Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market cover, and what was the market size in 2025?
In 2025, the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market size was estimated at USD 10.49 billion. The report covers the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Europe Insulin Drugs And Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Market size for years: 2026, 2027, 2028, 2029, 2030 and 2031.
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