CRISPR Technology Market Size and Share

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Compare market size and growth of CRISPR Technology Market with other markets in Healthcare Industry

CRISPR Technology Market Analysis by Mordor Intelligence

The CRISPR technology market size stood at USD 4.53 billion in 2025 and is projected to reach USD 11.23 billion by 2030, reflecting a 19.89% CAGR. Rapid growth follows the December 2023 FDA clearance of CASGEVY, the first CRISPR therapy for β-thalassemia and sickle-cell disease. Capital inflows continue as prime-editing trials report positive human data and falling reagent costs widen the user base. Consolidation around delivery know-how is visible through investments such as Regeneron’s stake in Mammoth Biosciences, while public bioeconomy initiatives in the United States, United Kingdom, China, and Australia support downstream manufacturing. The CRISPR technology market benefits from clearer regulatory guidance and a growing pipeline that now spans hematology, oncology, neurological, and agricultural use cases.

Key Report Takeaways

  •  By product category, Kits & Reagents led with 43.23% revenue share in 2024; Design Tools/Software is forecast to register the fastest 21.34% CAGR through 2030.
  • By service, Cell Line Engineering accounted for 38.21% of the CRISPR technology market share in 2024, while CRISPR Screening Services are expected to advance at a 21.78% CAGR to 2030.
  • By technology, CRISPR/Cas9 commanded 71.54% share in 2024; Prime Editing is projected to grow at a 21.45% CAGR over the same period.
  • By application, Biomedical applications held 56.43% of the CRISPR technology market size in 2024 and Environmental & Synthetic Biology is set to expand at a 22.31% CAGR through 2030.
  • By end user, Pharmaceutical & Biotechnology Companies represented 50.32% share in 2024, whereas Contract Research Organizations are anticipated to record the highest 22.56% CAGR to 2030.
  • By geography, North America captured 42.56% of 2024 revenue; Asia-Pacific is expected to post the fastest 20.34% CAGR between 2025 and 2030.

Segment Analysis

By Product: Reagents Anchor Revenue While Software Leads Growth

Kits & Reagents accounted for 43.23% revenue in 2024, reflecting essential consumables like guide RNAs, nucleases, and delivery mixes used in every experiment. The segment delivers recurring sales that smooth research-funding cycles. Design Tools/Software is the fastest-growing category with a 21.34% CAGR, propelled by AI-assisted platforms that simplify experimental planning. Enzymes maintain steady demand as improved fidelity variants launch yearly, while custom guide-RNA catalogs expand to meet precision-therapy needs. CRISPR libraries support pooled screens in drug discovery, and other specialized delivery reagents address tissue-specific challenges.

Historical growth from 2019-2024 emphasized consumable expansion, while the 2025-2030 horizon focuses on integrated platforms bundling cloud design, lab automation, and reagent fulfillment. Vendors differentiate on workflow performance rather than standalone product specs. The CRISPR technology market size for kits & reagents is projected to surpass USD 5.4 billion by 2030, equal to roughly 48% of total revenue. Bundled subscriptions lock customers into single-vendor ecosystems, sustaining margins despite commodity pressure.

CRISPR Technology Market: Market Share by Product
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Note: Segment shares of all individual segments available upon report purchase

Kits & Reagents Segment in CRISPR Technology Market

The Kits & Reagents segment is projected to exhibit the highest growth rate of approximately 21% during the forecast period 2024-2029. This accelerated growth is attributed to the increasing research and development activities and growing awareness about CRISPR technology across various applications. The segment's expansion is supported by the wide-ranging presence of innovative tools and CRISPR gene editing kits for gene modification experiments, fulfilling the growing need for genome editing solutions. The development of comprehensive CRISPR kits that enhance the efficiency of gene editing processes has also contributed to the segment's rapid growth. Furthermore, several companies are actively engaged in launching new products and forming strategic partnerships to expand their CRISPR kits and reagents portfolio, driving the segment's exceptional growth trajectory.

By Service: Engineering Dominates While Screening Accelerates

Cell-line engineering captured 38.21% of 2024 revenue because pharmaceutical pipelines rely on bespoke models for target validation. Technical complexity justifies premium fees and long contracts. CRISPR screening services post a 21.78% CAGR as functional-genomics programs require high-throughput loss-of-function and gain-of-function assays. gRNA design and synthesis underpins every application, while animal-model generation supports disease research where cell lines fall short.

By Technology: Cas9 Dominates but Precision Platforms Surge

CRISPR/Cas9 delivered 71.54% share in 2024 thanks to broad validation, simple design rules, and abundant off-the-shelf kits. Yet safety concerns around double-strand breaks push demand toward prime editing, base editing, and compact Cas12/13 systems. Prime editing posts a 21.45% CAGR, driven by 2025 clinical data that showed durable correction without translocations. Base editors target point-mutation diseases unsuitable for full re-writes. Cas13 unlocks transcript-level interventions with lower immunogenicity. Innovation pivots toward delivery-ready compact nucleases like Scribe’s X-editing family that fit AAV capsids, lowering dose requirements. Tool suppliers bundle high-fidelity variants with lipid nanoparticles to improve in-vivo performance. The CRISPR technology market share enjoyed by Cas9 is forecast to slip yet remain above 55% by 2030 given entrenched research usage, while combined precision platforms could exceed 30%, reflecting rapid clinical adoption.

By Application: Biomedical Underpins Revenue while Environment Gathers Pace

Biomedical uses generated 56.43% of 2024 revenue because therapies command premium pricing and require large reagent volumes. Oncology, hematology, and rare diseases dominate trial pipelines, with several programs in Phase III. Environmental & Synthetic Biology shows 22.31% CAGR as climate mandates fuel demand for carbon-negative microbes and biodegradable-plastic production strains. Agricultural applications gain momentum on regulatory clarity for non-transgenic crops in the European Union and expanding acreage in China, India, and Brazil. Industrial biotechnology uses CRISPR to fine-tune enzyme pathways for bio-based chemicals, cutting fossil inputs. The CRISPR technology industry navigates different capital cycles: healthcare benefits from venture and pharma funding, whereas environmental plays rely on government grants and corporate sustainability budgets. By 2030, biomedical may still represent about half of total sales, but environmental and industrial verticals together can close the gap as scale economies emerge.

CRISPR Technology Market: Market Share by Application
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Note: Segment shares of all individual segments available upon report purchase

By End User: Pharma Leads, CROs Scale Fast

Pharmaceutical & Biotechnology Companies held 50.32% share in 2024, reflecting internal pipeline investments and partnership payments. Yet these firms increasingly outsource specialized steps to Contract Research Organizations, which record a 22.56% CAGR through 2030. CRO expansion aligns with cost-control and speed-to-clinic pressures, driving multi-year master-service agreements. Academic institutes remain pivotal in discovery but lag in downstream manufacturing spending. Other end users—seed companies, environmental groups, bio-materials start-ups—collectively form a growing long-tail segment. The CRISPR technology market size generated by CRO engagements is on track to double by 2030. Competition amplifies as large CDMOs enter the space, bundling viral-vector manufacturing and cell-processing suites with gene-editing services.

Geography Analysis

CRISPR Technology Market in North America

North America held 42.56% of 2024 revenue, driven by mature venture funding, favorable reimbursement, and clear FDA guidance that de-risks clinical investment. Boston, San Francisco, and San Diego anchor ecosystems where CRISPR Therapeutics, Editas Medicine, and Beam Therapeutics run multi-indication pipelines. The 2025 National Biotechnology Initiative Act expands tax credits for GMP capacity, strengthening domestic supply chains and cementing regional dominance[2]House of Representatives, “National Biotechnology Initiative Act of 2025,” congress.gov.

Asia-Pacific is the fastest-growing region at 20.34% CAGR to 2030, led by China’s multi-billion-dollar synthetic-biology parks and relaxed rules for gene-edited crops[3]CSIRO, “Synthetic Biology Roadmap,” csiro.au. Australia’s roadmap foresees AUD 30 billion value by 2040 and funds industrial enzymes, while Singapore subsidizes GMP suites to lure global clinical-trial production. India’s contract-research sector leverages cost advantages and skilled labor to capture discovery outsourcing, broadening regional participation in the CRISPR technology market.

Europe remains influential through deep regulatory expertise and generous public grants. The United Kingdom’s GBP 100 million Engineering Biology fund finances fermentation hubs, and the EU-backed SYNBEE accelerator spans 25 nations, nurturing start-ups in food and environmental editing. EMA guidelines standardize genome-editing submissions, providing predictability despite stringent data demands. Central-eastern EU members court agricultural trials on climate-resilient wheat and maize, reflecting a pan-continental spread of CRISPR technology market applications.

CRISPR Technology Market CAGR (%), Growth Rate by Region
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Competitive Landscape

The tools segment is moderately concentrated as Thermo Fisher Scientific, Merck KGaA, and Danaher control global reagent supply and distribution. Their advantage lies in GMP manufacturing scale, validated quality systems, and multi-channel sales footprints. 

Therapeutics remain less concentrated; CRISPR Therapeutics, Intellia, Editas, and Beam each hold single-digit revenue shares, none exceeding 15% of overall pipeline investment. Intellectual-property disputes between UC Berkeley and Broad Institute continue, but larger companies mitigate risk by licensing both estates, creating a barrier for smaller entrants.

Strategic partnerships shape competition. Regeneron–Mammoth, Sanofi–Scribe, and Danaher–IGI exemplify pharma preference for compact nucleases and manufacturing leverage. Delivery innovation remains the main white space; startups engineer lipid nanoparticles and viral vectors tuned to tissue tropism, and incumbents respond through acquisitions. AI-powered design suites like CRISPR-GPT and OpenCRISPR-1 democratize access, prompting tool giants to integrate software subscriptions into reagent bundles. Over 2025-2030, winners will combine broad patent coverage, digital design ecosystems, scalable GMP production, and proven clinical safety to consolidate shares in the CRISPR technology market.

CRISPR Technology Industry Leaders

  1. Merck KGaA

  2. GenScript

  3. Danaher Corporation (Integrated DNA Technologies (IDT))

  4. PerkinElmer Inc. (Horizon Discovery Group)

  5. ThermoFisher Scientific, Inc.

  6. *Disclaimer: Major Players sorted in no particular order
CRISPR Technology Market
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Recent Industry Developments

  • May 2025: Prime Medicine announced up to 72% gene correction in Alpha-1 Antitrypsin Deficiency mice and plans an IND/CTA by mid-2026.
  • May 2025: Aldevron and Integrated DNA Technologies delivered the first personalized mRNA CRISPR therapy for an infant with urea-cycle disorder within six months.
  • May 2025: Corteva invested USD 25 million in Pairwise to accelerate climate-resilient crops via the Fulcrum platform
  • May 2025: Nature reported the first human prime-editing trial restoring immune function in chronic granulomatous disease.
  • March 2025: AWS and ElevateBio partnered on generative-AI-powered gene-editing workflows.
  • January 2025: Scribe Therapeutics hit a milestone in its USD 1.2 billion in-vivo CRISPR pact with Sanofi.

Table of Contents for CRISPR Technology Industry Report

1. Introduction

  • 1.1 Study Assumptions & Market Definition
  • 1.2 Scope Of The Study

2. Research Methodology

3. Executive Summary

4. Market Landscape

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Expanding Clinical Pipeline For Genetic Disorders
    • 4.2.2 Surge In Agri-Biotech Gene-Edited Crop Approvals
    • 4.2.3 Falling Genome Editing Costs And Tool Democratization
    • 4.2.4 Strategic Pharma-Biotech Alliances For In-Vivo CRISPR Therapies
    • 4.2.5 AI-Enabled Functional Genomics Discovery Acceleration
    • 4.2.6 Government Bioeconomy Programs Supporting Synthetic Biology Scale-Up
  • 4.3 Market Restraints
    • 4.3.1 Stringent Regulatory Scrutiny And Evolving Compliance Frameworks
    • 4.3.2 Unresolved Ethical Concerns Around Germline Editing
    • 4.3.3 Complex Intellectual Property Landscape And Litigation Risks
    • 4.3.4 Limited Delivery Modalities For In-Vivo Editing
  • 4.4 Regulatory Landscape
  • 4.5 Technological Outlook
  • 4.6 Porter's Five Forces Analysis
    • 4.6.1 Threat Of New Entrants
    • 4.6.2 Bargaining Power Of Buyers
    • 4.6.3 Bargaining Power Of Suppliers
    • 4.6.4 Threat Of Substitutes
    • 4.6.5 Competitive Rivalry

5. Market Size & Growth Forecasts (Value, USD)

  • 5.1 By Product
    • 5.1.1 Enzymes
    • 5.1.2 Kits & Reagents
    • 5.1.3 Guide RNA
    • 5.1.4 CRISPR Libraries
    • 5.1.5 Design Tools / Software
    • 5.1.6 Other Products
  • 5.2 By Service
    • 5.2.1 gRNA Design & Synthesis
    • 5.2.2 Cell Line Engineering
    • 5.2.3 Animal Model Generation
    • 5.2.4 CRISPR Screening Services
    • 5.2.5 Other Services
  • 5.3 By Technology
    • 5.3.1 CRISPR/Cas9
    • 5.3.2 CRISPR/Cas12
    • 5.3.3 CRISPR/Cas13
    • 5.3.4 Base Editing
    • 5.3.5 Prime Editing
    • 5.3.6 Other Technologies
  • 5.4 By Application
    • 5.4.1 Biomedical
    • 5.4.2 Agricultural
    • 5.4.3 Industrial Biotechnology
    • 5.4.4 Environmental & Synthetic Biology
    • 5.4.5 Other Applications
  • 5.5 By End User
    • 5.5.1 Pharmaceutical & Biotechnology Companies
    • 5.5.2 Academic & Government Research Institutes
    • 5.5.3 Contract Research Organizations
    • 5.5.4 Other End Users
  • 5.6 Geography
    • 5.6.1 North America
    • 5.6.1.1 United States
    • 5.6.1.2 Canada
    • 5.6.1.3 Mexico
    • 5.6.2 Europe
    • 5.6.2.1 Germany
    • 5.6.2.2 United Kingdom
    • 5.6.2.3 France
    • 5.6.2.4 Italy
    • 5.6.2.5 Spain
    • 5.6.2.6 Rest of Europe
    • 5.6.3 Asia-Pacific
    • 5.6.3.1 China
    • 5.6.3.2 Japan
    • 5.6.3.3 India
    • 5.6.3.4 Australia
    • 5.6.3.5 South Korea
    • 5.6.3.6 Rest of Asia-Pacific
    • 5.6.4 Middle East & Africa
    • 5.6.4.1 GCC
    • 5.6.4.2 South Africa
    • 5.6.4.3 Rest of Middle East & Africa
    • 5.6.5 South America
    • 5.6.5.1 Brazil
    • 5.6.5.2 Argentina
    • 5.6.5.3 Rest of South America

6. Competitive Landscape

  • 6.1 Market Concentration
  • 6.2 Market Share Analysis
  • 6.3 Company Profiles (includes Global level Overview, Market level overview, Core Business Segments, Financials, Headcount, Key Information, Market Rank, Market Share, Products and Services, and analysis of Recent Developments)
    • 6.3.1 Thermo Fisher Scientific
    • 6.3.2 Merck KGaA
    • 6.3.3 Danaher (IDT)
    • 6.3.4 Agilent Technologies
    • 6.3.5 GenScript
    • 6.3.6 PerkinElmer (Horizon Discovery)
    • 6.3.7 New England Biolabs
    • 6.3.8 Cellecta
    • 6.3.9 Origene Technologies
    • 6.3.10 Synthego
    • 6.3.11 CRISPR Therapeutics
    • 6.3.12 Editas Medicine
    • 6.3.13 Intellia Therapeutics
    • 6.3.14 Caribou Biosciences
    • 6.3.15 Beam Therapeutics
    • 6.3.16 Sangamo Therapeutics
    • 6.3.17 Precision Biosciences
    • 6.3.18 ERS Genomics
    • 6.3.19 Takara Bio
    • 6.3.20 Integrated Micro-Biome Therapeutics

7. Market Opportunities & Future Outlook

  • 7.1 White-Space & Unmet-Need Assessment
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Global CRISPR Technology Market Report Scope

As per the scope of the report, CRISPR technology is a tool for editing genomes. It enables researchers to alter DNA sequences and further modify gene function easily. It has several potential applications, including treating and preventing disease spread, correcting genetic defects, and improving crops.

The CRISPR technology market is segmented by product, application, end user, and geography. The product segment is further segmented into enzymes, kits, and reagents, guide RNA, and other products. The application segment is further divided into biomedical, agricultural, industrial, and other applications. The end user segment is further bifurcated into pharmaceutical companies and biotechnology companies, academics and government research institutes, and other end users (CROs, etc.). By geography, the market is further segmented into North America, Europe, Asia-Pacific, Middle East And Africa, and South America. The report offers the value (in USD) for the segments mentioned above.

By Product Enzymes
Kits & Reagents
Guide RNA
CRISPR Libraries
Design Tools / Software
Other Products
By Service gRNA Design & Synthesis
Cell Line Engineering
Animal Model Generation
CRISPR Screening Services
Other Services
By Technology CRISPR/Cas9
CRISPR/Cas12
CRISPR/Cas13
Base Editing
Prime Editing
Other Technologies
By Application Biomedical
Agricultural
Industrial Biotechnology
Environmental & Synthetic Biology
Other Applications
By End User Pharmaceutical & Biotechnology Companies
Academic & Government Research Institutes
Contract Research Organizations
Other End Users
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa GCC
South Africa
Rest of Middle East & Africa
South America Brazil
Argentina
Rest of South America
By Product
Enzymes
Kits & Reagents
Guide RNA
CRISPR Libraries
Design Tools / Software
Other Products
By Service
gRNA Design & Synthesis
Cell Line Engineering
Animal Model Generation
CRISPR Screening Services
Other Services
By Technology
CRISPR/Cas9
CRISPR/Cas12
CRISPR/Cas13
Base Editing
Prime Editing
Other Technologies
By Application
Biomedical
Agricultural
Industrial Biotechnology
Environmental & Synthetic Biology
Other Applications
By End User
Pharmaceutical & Biotechnology Companies
Academic & Government Research Institutes
Contract Research Organizations
Other End Users
Geography
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa GCC
South Africa
Rest of Middle East & Africa
South America Brazil
Argentina
Rest of South America
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Key Questions Answered in the Report

What was the CRISPR technology market size in 2025?

It stood at USD 4.53 billion, reflecting the first full year of commercial therapy sales.

How fast is the CRISPR technology market expected to grow to 2030?

The forecast indicates a 19.89% CAGR, pushing revenue to about USD 11.23 billion.

Which product segment holds the largest share today?

Kits & Reagents lead with 43.23% of 2024 revenue owing to recurring consumables demand.

What region will expand quickest through 2030?

Asia-Pacific is projected to grow at a 20.34% CAGR because of strong public funding and manufacturing investment.

Why are Contract Research Organizations gaining importance?

Pharma companies outsource complex editing tasks to CROs to control costs and speed up development, driving a 22.56% CAGR in CRO demand.

What is the main restraint facing the CRISPR technology market?

Strict and evolving regulatory frameworks add time and cost to both therapeutic and agricultural approvals, weighing on growth potential.

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