Acute Myeloid Leukemia Market Size & Share Analysis - Growth Trends & Forecasts (2023 - 2028)

The Acute Myeloid Leukemia Market is segmented by chemotherapy (Cytarabine, Anthracycline Drugs, Alkylating Agents, Anti-metabolites, Tyrosine Kinase Inhibitors, hormonal therapy, and other chemotherapies) and geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The report offers the value in (USD million) for the above segments.

Acute Myeloid Leukemia Market Size

Acute Myeloid Leukemia Market Summary
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Study Period 2019-2027
Market Size (2023) USD 1.66 Billion
Market Size (2028) USD 2.70 Billion
CAGR (2023 - 2028) 10.15 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Acute Myeloid Leukemia Market Major Players

*Disclaimer: Major Players sorted in no particular order


Need a report that reflects how COVID-19 has impacted this market and its growth?

Acute Myeloid Leukemia Market Analysis

The Acute Myeloid Leukemia Market size is expected to grow from USD 1.66 billion in 2023 to USD 2.70 billion by 2028, at a CAGR of 10.15% during the forecast period (2023-2028).

The COVID-19 pandemic has significantly impacted the acute myeloid leukemia market. Cancer treatments such as chemotherapy and immune suppressants damage the patient's immune system. This weakened immune system of the target population is expected to create a risk of Covid-19 infection. Various research was conducted to find the impact of Covid 19 on AML patients. According to the National Cancer Institute (NCI), in August 2021, people with cancer had a higher risk of severe illness from COVID-19.

Furthermore, according to an article published by the American Society of Hematology, in January 2022, due to anticipated shortfalls in blood bank supplies during the COVID-19 pandemic, blood transfusion thresholds were lowered while taking into account significant local/regional variability. Patients who tested positive for COVID-19 had got their treatment delayed. Since newly discovered AML is a treatment-emergent, intensive induction chemotherapy was made available to eligible AML patients. Thus, increased risk for an AML in a pandemic and the shortage of other treatment modalities are expected to drive the demand for AML drugs.

The key factors propelling the growth of this market are the high incidence and prevalence of acute myeloid leukemia, advancements in pharmacology and molecular biology to promote drug development, and increasing investments in research and development by pharmaceutical companies. According to the American Cancer Society, it is estimated that there will be 60,650 new leukemia cancer cases, of which 24,000 are expected to die in 2022 in the US. In addition, according to the same source, 20,050 new cases of acute myeloid leukemia (AML) are estimated in 2022 in the US. It will lead to increased adoption of AML therapies. The rising prevalence of AML in developed countries such as the US is expected to drive this market's growth.

Furthermore, with the rising investment in research and development, there is an increasing number of clinical trials conducted to demonstrate the effectiveness of the drugs. It is expected to drive the market over the forecast period. For Instance, according to the United States National Library of Medicine, a study titled 'Daunorubicin or Idarubicin With Cytarabine Plus Quizartinib vs. Physician's Choice in Newly Diagnosed FLT3-ITD+ AML (Q-SOC)' is in Phase III of clinical trials. The study was estimated to start in November 2021 and be complete in March 2025.

Thus, the abovementioned factors are impacting the market growth of the Acute myeloid leukemia market. However, stringent regulations on drugs and complications related to chemotherapy are the factors expected to restrain the market growth.

Acute Myeloid Leukemia Market Trends

This section covers the major market trends shaping the Acute Myeloid Leukemia Market according to our research experts:

Cytarabine is Expected to Witness High Growth Over the Forecast Period

Cytarabine can treat different leukemia forms, including acute and chronic myelogenous leukemia (AML and CML), acute lymphocytic leukemia (ALL), and acute promyelocytic leukemia (APL). It can also treat Hodgkin's lymphoma, meningeal leukemia, and other types of lymphoma (cancers found in the lining of the brain and spinal cord). Due to its effectiveness in treating acute myeloid leukemia, Cytarabine is widely used during chemotherapy. Organizations working for cancer, such as Macmillan Cancer Support, have stated that Cytarabine is more effective for acute myeloid leukemia, which is why the drug is used widely. Therefore, this sub-segment is expected to have a significant market share in the chemotherapy segment.

Rising approvals for Cytarabine by the US Food and Drug Administration for treating acute myeloid leukemia are also expected to drive the growth of this market. For Instance, in March 2021, Jazz Pharmaceuticals PLC received US Food and Drug Administration (FDA) approval for a revised label for Vyxeos (daunorubicin and Cytarabine), including a new indication to treat newly-diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC) in pediatric patients aged one year and older.​ Furthermore, in January 2022, the US Food and Drug Administration (FDA) granted the company orphan drug designation for its pipeline compound OM-301 to treat acute myeloid leukemia (AML) developed by Oncolyze Inc. These approvals from the regulatory authorities are driving the growth of the market.​

Therefore, owing to the abovementioned factors, the cytarabine segment is expected to show a significant share during the forecast period.

Acute Myeloid Leukemia Market : New Cases and Deaths of Leukemia, Global 2022

North America Holds a Major Share and Expected to do Same during the Forecast Period

North America currently dominates the market for acute myeloid leukemia and is expected to continue its stronghold over the forecast period. The rising prevalence of acute myeloid leukemia cases in the US is expected to drive the growth of this market in this region. For instance, according to the American Society of Clinical Oncology in 2021, acute myeloid leukemia is a rare malignancy that accounts for around 1% of all cancers. In the US, an estimated 20,240 people of all ages (11,230 men and boys and 9,010 women and girls) were diagnosed with this disease in 2021. AML is the second most prevalent kind of leukemia in adults and children, with adults accounting for the majority of occurrences. Therefore, the rising prevalence of acute myeloid leukemia in the US will lead to higher therapy adoption for this disease, thereby expected to drive the growth of this market in North America.

Furthermore, rising research and development and product launches for acute myeloid leukemia are further expected to drive market growth in this region. For instance, in May 2022, the FDA approved ivosidenib (Tibsovo, Servier Pharmaceuticals LLC) in combination with azacitidine (azacitidine for injection) for newly diagnosed acute myeloid leukemia (AML). It includes a susceptible IDH1 mutation detected by an FDA-approved test in adults 75 years or older or with comorbidities that preclude intensive induction chemotherapy.

Therefore, the market is expected to show a significant share in North America due to the abovementioned factors.

Acute Myeloid Leukemia MarketGrowth Rate by Region

Acute Myeloid Leukemia Industry Overview

The acute myeloid leukemia market is consolidated in nature due to the presence of a few companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international and local companies that hold market shares and are well known, including Novartis AG, Teva Pharmaceuticals, Pfizer, Bristol Myer Squibb, and Sanofi-Aventis (Genzyme Corporation), among others.

Acute Myeloid Leukemia Market Leaders

  1. Pfizer Inc.

  2. Novartis AG

  3. Sanofi-Aventis (Genzyme Corporation)

  4. Otsuka holdings co., ltd.

  5. Bristol Myers Squibb

*Disclaimer: Major Players sorted in no particular order

Acute Myeloid Leukemia Market Concentration

Acute Myeloid Leukemia Market News

  • January 2022- Oncolyze announced the receival of FDA Orphan Drug Designation for OM-301 to treat acute myeloid leukemia (AML).
  • December 2021- the European Commission granted Orphan Drug Designation to SNDX-5613, a highly selective oral menin inhibitor, to treat acute myeloid leukemia (AML) developed by Syndax Pharmaceuticals Inc.

Acute Myeloid Leukemia Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 High Incidence and Prevalence of Acute Myeloid Leukemia

      2. 4.2.2 Advancement in Pharmacology and Molecular Biology to Promote Drug Development

      3. 4.2.3 Increasing Investments in Research and Development

    3. 4.3 Market Restraints

      1. 4.3.1 Stringent Regulations on Drugs

      2. 4.3.2 Complications Related to Chemotherapy

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Bargaining Power of Suppliers

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Threat of New Entrants

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 5.1 Chemotherapy

      1. 5.1.1 Cytarabine

      2. 5.1.2 Anthracycline Drugs

      3. 5.1.3 Alkylating Agents

      4. 5.1.4 Anti-metabolites

      5. 5.1.5 Tyrosine Kinase Inhibitors

      6. 5.1.6 Hormonal Therapy

      7. 5.1.7 Other Chemotherapies

    2. 5.2 Geography

      1. 5.2.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.2.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.2.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.2.4 Middle East & Africa

        1. GCC

        2. South Africa

        3. Rest of Middle East & Africa

      5. 5.2.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Bristol-Myers Squibb Company (Celgene Corporation)

      2. 6.1.2 Novartis AG

      3. 6.1.3 Genmab AS

      4. 6.1.4 Otsuka Holdings Co. Ltd

      5. 6.1.5 Sanofi-Aventis (Genzyme Corporation)

      6. 6.1.6 Teva Pharmaceutical (Cephalon Inc.)

      7. 6.1.7 Pfizer Inc.

      8. 6.1.8 F. Hoffmann-La Roche Ltd

      9. 6.1.9 Sunesis Pharmaceuticals Inc.

      10. 6.1.10 Astellas Pharma

      11. 6.1.11 Oncolyze Inc.

      12. 6.1.12 Syndax Pharmaceuticals Inc.

      13. 6.1.13 AbbVie Inc.

      14. 6.1.14 Amgen Inc.

      15. 6.1.15 Agios Pharmaceuticals Inc.

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments

Acute Myeloid Leukemia Industry Segmentation

As per the scope of this report, acute myeloid leukemia is also known as acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia, or acute non-lymphocytic leukemia. In acute myeloid leukemia, abnormal white blood cells are rapidly collected in the bone marrow and disturb the production of normal blood cells. 

The Acute Myeloid Leukemia Market is segmented by chemotherapy (Cytarabine, Anthracycline Drugs, Alkylating Agents, Anti-metabolites, Tyrosine Kinase Inhibitors, hormonal therapy, and other chemotherapies) and geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major global regions. The report offers the value in (USD million) for the above segments. 


Anthracycline Drugs
Alkylating Agents
Tyrosine Kinase Inhibitors
Hormonal Therapy
Other Chemotherapies
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle East & Africa
South Africa
Rest of Middle East & Africa
South America
Rest of South America

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Acute Myeloid Leukemia Market Research FAQs

The Acute Myeloid Leukemia Market size is expected to reach USD 1,664.66 million in 2023 and grow at a CAGR of 10.15% to reach USD 2,699.28 million by 2028.

In 2023, the Acute Myeloid Leukemia Market size is expected to reach USD 1,664.66 million.

Pfizer Inc., Novartis AG, Sanofi-Aventis (Genzyme Corporation), Otsuka holdings co., ltd. and Bristol Myers Squibb are the major companies operating in the Acute Myeloid Leukemia Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2023-2027).

In 2023, the North America accounts for the largest market share in the Acute Myeloid Leukemia Market.

Acute Myeloid Leukemia Industry Report

Statistics for the 2023 Acute Myeloid Leukemia market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Acute Myeloid Leukemia analysis includes a market forecast outlook to 2028 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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