Topical Analgesic Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The Global Topical Analgesics / Pain Relief Market is segmented by Drug Type (Non-Opioids, Opioids), Formulation (Cream, Patch, Spray, Gel, Other Formulations), Type (Over the Counter (OTC) Analgesic and Prescription Analgesic), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market size and forecasts are provided in terms of value (USD million) for all the above segments.

Topical Analgesic Market Size

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Topical Analgesic Market Summary
Study Period 2019 - 2029
Base Year For Estimation 2023
CAGR 6.44 %
Fastest Growing Market Asia Pacific
Largest Market North America
Market Concentration Medium

Major Players

Topical Analgesic Market

*Disclaimer: Major Players sorted in no particular order


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Topical Analgesic Market Analysis

The topical analgesic market size is expected to grow from USD 4.58 billion in 2023 to USD 6.26 billion by 2028, registering a CAGR of 6.44% during the forecast period.

The COVID-19 pandemic impacted the studied market during the pandemic due to supply chain alterations and altered production of various consumer healthcare products. However, consumer healthcare products like pain management medicines had high demand during the pandemic. For instance, according to the latest data from the ZOE Health Study in December 2022, the top symptoms reported by contributors in the United Kingdom with positive COVID-19 tests included headache, muscle aches, pains, and other respiratory symptoms. Headaches and muscle aches were reported as top symptoms from the initial stages of the COVID-19 pandemic. An increase in the number of individuals who experienced headaches, body discomfort, and fatigue due to COVID-19-related stress boosted sales of painkillers, specifically topical painkillers, due to their easy application. Hence, the market initially experienced a slight adverse impact but attained growth due to the high demand for topical analgesics and is expected to continue the steady growth over the coming years.

Certain factors that are driving the market growth include the high prevalence of arthritis, rising cases of sports-related injuries, and the growing geriatric population. Arthritis is the most common joint disease but also one of the major causes of disability in people aged 65 years and above. Pain is a prominent feature of many rheumatic and musculoskeletal diseases (RMDs) and is the source of much personal, financial, and societal burden. For instance, as per the report published by the European Pain Federation EFIC in October 2022, more than 120 million RMDs of all ages are estimated to experience pain in Europe. Similarly, according to the report published by the Deutsches Rheuma-Forschungszentrum in January 2023; currently, 1.5-2.1 million adults and 14,000 children have rheumatic diseases in Germany. The most common are rheumatoid arthritis and spondyloarthritis. Thus, the high burden of pain diseases like arthritis increases the need for topical analgesics, likely boosting the market growth.

Furthermore, the new product approvals and launches increase the widespread distribution of products in various regions, likely boosting market growth. For instance, in June 2022, Lumiera Health Inc. launched its Awaye pain relief cream in the United States market. Awaye relieves acute and chronic pain by exploiting the CB2 receptors of the endocannabinoid system. Thus, all the factors above, like the high prevalence of arthritis and new product approvals and launches, increase the demand for topical analgesics, likely propelling the market over the forecast period.

However, side effects related to topical analgesics are expected to hinder the market's growth over the forecast period.

Topical Analgesic Market Trends

Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Under Non-opioids Segment are Expected to Hold Significant Share in the Market Over the Forecast Period

NSAIDs work to reduce pain and inflammation by inhibiting enzymes called cyclooxygenases (COX). Several NSAIDs are available as creams and gels for topical use. These agents have been shown to have similar benefits to taking NSAIDs in pill form in osteoarthritis and low back pain. Topical use may be safer than the pill form, which has the common side effect of gastrointestinal discomfort. The rising burden of chronic pain and inflammation caused by various musculoskeletal disorders and rising sports-related injuries is expected to have a high demand for topical NSAIDs, likely boosting the market growth.

Sport-related injuries, such as ligament sprains, muscle sprains, tennis elbow, supraspinatus tendinitis, and others, are increasing among young athletes. For instance, according to an article published in Translational Pediatrics in February 2022, it was observed that about 8.6 million athletes suffer from sports-related injuries each year in the United States. Similarly, as per the report published by the National High School Sports-Related Injury Surveillance Study in August 2022, for the academic year 2021/22 in the United States, there were 4,998 injuries reported, with an injury incidence of 2.02 injuries per 1,000 athletes' exposures in the 20 sports. Thus, the high incidence of these sports injuries increases the need for topical analgesics for immediate relief, which likely propels the market growth over the study period.

The new product launches increase the availability of products to the public, which likely propels market growth. For instance, in December 2022, Lupin Limited launched an authorized generic PENNSAI (Diclofenac Sodium Topical Solution), 2% w/w of Horizon Pharma Therapeutics. Thus, all the abovementioned factors, like new product launches and increasing sport-related injuries, increase the demand for topical NSAIDs segment growth over the forecast period.

Topical Analgesic Market: Total Number of Sports-related Injuries, In Thousand, By Sport, United States, 2021

North America is Expected to Have the Largest Market Share Over the Forecast Period

North America is estimated to have a major market share due to the rising prevalence of pain-related diseases and disorders such as migraines, musculoskeletal disorders, and neuropathic pain, as well as the rising number of sports-related injuries. In addition, the growing approval of drugs by the drug regulatory and novel product launches by the key market players in the region is further expected to boost market growth during the study period.

According to the National Safety Council (NSC), in 2021, exercise equipment accounted for about 409,224 injuries in the United States, the most in any sports and recreation category. The injuries caused by bicycles and accessories accounted for 375,797 in 2021. As per the same source, the United States surged 20% in 2021 following a record-low number of sports and recreational injuries reported in 2020. In 2021, 3.2 million people were treated in emergency departments for sports and recreational equipment injuries. Thus, high sports-related injuries are expected to drive the demand for topical analgesics in the region.

The new product launches increase the availability of products, which is likely to have a significant impact on the market. For instance, in January 2023, Yaral Pharma Inc. launched a diclofenac epolamine topical system 1.3%, the authorized generic of IBSA Pharma's Flector (diclofenac epolamine) topical system in the United States. These authorized generics are poised to rapidly expand their product line and will likely have significant market growth in the region.

Therefore, owing to the abovementioned factors, the growth of the topical analgesics market in North America is expected to drive over the forecast period.

Topical Analgesic Market - Growth Rate by Region

Topical Analgesic Industry Overview

The topical analgesic market is highly fragmented, and key players manufacture most topical analgesic products. The leaders in this industry have established their position in the market, and these manufacturers have a wide product range and an extensive distribution system worldwide. Some of the key players in the market are Haleon plc, Johnson & Johnson, Sanofi, Reckitt Benckiser Group PLC, Sun Pharmaceutical Industries Ltd, Bayer AG, and others.

Topical Analgesic Market Leaders

  1. Johnson & Johnson

  2. Sun Pharmaceutical Industries Ltd

  3. Haleon plc

  4. Sanofi

  5. Reckitt Benckiser Group PLC

*Disclaimer: Major Players sorted in no particular order

Topical Analgesic Market Concentration
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Topical Analgesic Market News

  • May 2023: Scilex Holding Company, a Sorrento Company, initiated Phase 2, a randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the safety and efficacy of SP-103 (lidocaine topical system) in subjects with acute low back pain.
  • February 2023: Aurobindo Pharma Limited and its subsidiary Aurolife Pharma LLC received final approval from the United States Food & Drug Administration (FDA) to manufacture and market Diclofenac Sodium Topical Solution USP, 2% w/w, which is bioequivalent and therapeutically equivalent to the reference listed drug (RLD), Pennsaid Topical Solution, 2% w/w.

Topical Analgesic Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increasing Prevalence of Arthritis

      2. 4.2.2 Rising Cases of Sports Related Injuries

      3. 4.2.3 Growing Geriatric Population

    3. 4.3 Market Restraints

      1. 4.3.1 Side Effects Related to Topical Analgesics

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Bargaining Power of Buyers/Consumers

      2. 4.4.2 Bargaining Power of Suppliers

      3. 4.4.3 Threat of New Entrants

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD)

    1. 5.1 By Drug Type

      1. 5.1.1 Non Opioids

        1. Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

        2. Capsaicin

        3. Lidocaine

        4. Methyl Salicylates

        5. Other Drug Types

      2. 5.1.2 Opioids

    2. 5.2 By Formulation

      1. 5.2.1 Cream

      2. 5.2.2 Patch

      3. 5.2.3 Spray

      4. 5.2.4 Gel

      5. 5.2.5 Other Formulations

    3. 5.3 By Type

      1. 5.3.1 Over the Counter (OTC) Analgesic

      2. 5.3.2 Prescription Analgesic

    4. 5.4 Geography

      1. 5.4.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.4.2 Europe

        1. United Kingdom

        2. Germany

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.4.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.4.4 Middle East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle East and Africa

      5. 5.4.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 AdvaCare Pharma

      2. 6.1.2 Haleon plc

      3. 6.1.3 Johnson & Johnson

      4. 6.1.4 Parker Laboratories, Inc

      5. 6.1.5 Hisamitsu Pharmaceutical co.,inc.

      6. 6.1.6 Sanofi

      7. 6.1.7 Sun Pharmaceutical Industries Ltd

      8. 6.1.8 Topricin (Topical BioMedics, Inc.)

      9. 6.1.9 Teva Pharmaceutical Industries Ltd

      10. 6.1.10 Bayer AG

      11. 6.1.11 Reckitt Benckiser Group PLC

      12. 6.1.12 Cipla Inc.

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Topical Analgesic Industry Segmentation

Topical analgesics are recommended when patients experience acute and chronic muscle and joint pain to relieve their symptoms. The products are applied directly to the skin instead of being injected or swallowed. The Topical Analgesic Market is Segmented by Drug Type (Non-Opioids and Opioids), Formulation (Cream, Patch, Spray, Gel, and Other Formulations), Type (Counter (OTC) Analgesic and Prescription Analgesic), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.

By Drug Type
Non Opioids
Nonsteroidal Anti-inflammatory Drugs (NSAIDS)
Methyl Salicylates
Other Drug Types
By Formulation
Other Formulations
By Type
Over the Counter (OTC) Analgesic
Prescription Analgesic
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle East and Africa
South Africa
Rest of Middle East and Africa
South America
Rest of South America
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Topical Analgesic Market Research FAQs

The Global Topical Analgesic Market is projected to register a CAGR of 6.44% during the forecast period (2024-2029)

Johnson & Johnson, Sun Pharmaceutical Industries Ltd, Haleon plc, Sanofi and Reckitt Benckiser Group PLC are the major companies operating in the Global Topical Analgesic Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Global Topical Analgesic Market.

The report covers the Global Topical Analgesic Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Global Topical Analgesic Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Topical Painkiller Industry Report

Statistics for the 2024 Topical Analgesic market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Topical Analgesic analysis includes a market forecast outlook to for 2024 to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Topical Analgesic Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)