Microbiome Sequencing Services Market Overview
The global microbiome sequencing services market was valued at USD 554.99 million in 2017, registering a CAGR of 19.21%, during 2018-2023. A microbiome is the unique collection of trillions of microorganisms in and on an individual’s body. The goal of human microbiome studies is to understand the role of microbes in health and disease. Human microbiome analysis is the study of microbial communities found in and on the human body. North America dominates the market due to a surge in technological advancement in next-generation sequencing (NGS) projects in the region.
Huge Investment in Microbiome Research Boost the growth of Microbiome Sequencing Services Market
The sequencing of metagenome offers a novel method in diagnosing and treating a wide range of chronic diseases, such as oncology, etc. The metagenome differs from person to person significantly, which is key to its diagnostic potential, due to which the government is investing a large number of funds for microbiome sequencing projects. In 2007, the US National Institutes of Health (NIH) funded USD 140 million to the Human Microbiome Project, which examines all the microorganisms in the human body. In 2008, the European Commission financed USD 29 million for Metagenomics of the Human Intestinal Tract project (MetaHIT). The Wall Street Journal in 2016, reported that from 2011 to 2015, venture funding in microbiome firms climbed by 458.5% to USD114.5 million. About USD 616.9 million was raised for microbiome companies in 2016, which is more than all of the venture investment in the microbiome space between 2011 to 2015 period.
Also, rising demand for NGS, surge in genomic research, and widening application area of microbiome sequencing, and a decline in the cost of sequencing are the major factors driving the growth of the market.
Lack of Skilled Technicians for NGS Data Analysis Hinders the growth of Microbiome Sequencing Services Market
Lack of technicians in the interpretation of sequencing data is the major factor restricting the growth of the microbiome sequencing services market. Microbiome sequencing generates a huge amount of data, which needs to be interpreted using advanced software. The lack of awareness and knowledge of advanced tools of data analysis among physicians and scientists is the major factor restricting the growth of the global microbiome sequencing services market. Further, government regulations and ethical & legal issues related to NGS are the also restraining the growth of the microbiome sequencing services market.
Market Segmentation Insights for the Microbiome Sequencing Services Market
The microbiome sequencing services market is segmented into technology, application, and end-user. By technology it is further segmented into Sequencing by Litigation (SBL), Sequencing by Synthesis (SBS), Short Gun Sequencing, Targeted Gene Sequencing, RNA Sequencing, and others. Sequencing by Synthesis (SBS) has dominated the market with a market share of about 47% in 2017. However, RNA Sequencing is growing rapidly with the highest CAGR in the market due to recent developments for instance, the development of Oligo Library Synthesis kit for RNA libraries, by Agilent, offer to draw down subsets of targets through custom mixtures of up to 60,000 different 150–200 bp oligonucleotides, allowing m-RNA targeted sequencing which can further propel the market growth over the forecast period.
By application, the market is further segmented into Gastro-Intestinal Diseases, Infectious Diseases, CNS Diseases, Oncology, and other applications. Gastro-intestinal diseases have the largest share which is about 35% due to the innovation of various products which are used in the treatment of inflammatory bowel disease (IBD) treatment, ulcerative colitis, and Crohn’s disease. For instance, Origin Sciences (United Kingdom) is a company developing sampling devices through its approved OriCol platform, which is also currently being tested for the validation of Calprotectin as a biomarker, for differential diagnosis of inflammatory bowel diseases. It also exhibits the highest CAGR in the application segment.
By end-user is segmented into Research and Academic Institutes, Pharmaceutical and Biotechnology Companies and Other End Users. Pharmaceutical and Biotechnology Companies has the maximum share in the market which is about 45%. Several established pharmaceutical companies are increasing their focus on microbiome R&D, powered by advancements in synthetic biology and microbial ecology, and thereby augmenting the growth of the market. Also, it is exhibiting the highest CAGR in the end-user segment.
North America to Dominate the Microbiome Sequencing Services Market
The microbiome sequencing services market is segmented by technology type, application, end user, and geography. By geography, it is segmented into North America, Europe, Asia-Pacific, Middle East & Africa, and South America.
North America dominates the microbiome sequencing services market, owing to factors, such as government support through funds for genomics research, consistent developments in sequencing technologies, and ease in availability of commercial solutions for NGS data analysis. Asia-Pacific is also expected to grow tremendously during the forecast period, owing to a growing number of research studies on cancer and inherited rare diseases and rising demand for next-generation sequencing for diagnosis and therapeutic applications.
Key Developments in the Microbiome Sequencing Services Market
- November 2017: MicroBiome Therapeutics, LLC launched first microbiome modulator. The product is described as an all-natural blend of prebiotics, including fermentable fiber and polyphenol antioxidants, in a patent-pending blend intended to help nurture and nourish beneficial microorganisms in the lower gut.
- June 2017: Zymo Research Corp. launched new kits for Microbiome Research at ASM Microbe 2017.
Major Companies: Clinical Microbiomics A/S, Baseclear B.V., EPIBIOME, Microbiome Insights Inc., Microbiome Therapeutics, LLC., MR DNA, Merieux Nutrisciences Corporation, Ubiome, Inc., Zymo Research Corp., and Second Genome, among others
Microbiome Sequencing Services Market Segmentation
- By Technology
- Sequencing by Litigation (SBL)
- Sequencing by Synthesis (SBS)
- Short Gun Sequencing
- Targeted Gene Sequencing
- RNA Sequencing
- By Application
- Gastro-Intestinal Diseases
- Infectious Diseases
- CNS Diseases
- By End User
- Research and Academic Institutes
- Pharmaceutical and Biotechnology Companies
- By Geography
- North America
- Asia Pacific
- South Korea
- Middle East and Africa
- South Africa
- South America
- North America
Country-Level Data Points Coverage and Deliverables for Microbiome Sequencing Services Market
Microbiome Sequencing Services Market Report Summary
Microbiome Sequencing Services Market
(2015 – 2023)
By technology type, the microbiome sequencing services market has been segmented into – sequencing by ligation, by synthesis, shot gun sequencing, targeted gene sequencing, RNA sequencing, and other technologies. By application, the market has been segmented into – gastrointestinal diseases, infectious diseases, CNS diseases, oncology, and other applications. On the basis of end user, the market has been segmented into research and academic institutes, pharmaceutical and biotechnology companies, and other end users.
North America (US, Canada, Mexico), Europe (UK, Germany, France, Italy Spain, Rest of Europe), Asia-Pacific (Japan, China, India, Australia, South Korea and Rest of Asia Pacific), Middle East & Africa (GCC, South Africa and Rest of MEA) and South America (Brazil, Argentina and Rest of South America)
November 2017: MicroBiome Therapeutics, LLC launched first microbiome modulator. The product is described as an all-natural blend of prebiotics, including fermentable fiber and polyphenol antioxidants, in a patent-pending blend intended to help nurture and nourish beneficial microorganisms in the lower gut.
Clinical Microbiomics A/S, Baseclear B.V., EPIBIOME, Microbiome Insights Inc., Microbiome Therapeutics, LLC., MR DNA, Merieux Nutrisciences Corporation, Ubiome, Inc., Zymo Research Corp., and Second Genome, among others.
Microbiome Sequencing Services Market offers latest trends, growth prospects, industry competitiveness, major players, regional share of market and forecast to 2023.
Reasons to Purchase Microbiome Sequencing Services Market Report
- Current and future global microbiome sequencing services market outlook in the developed and emerging markets
- Analysis of various perspectives of the market with the help of Porter’s five forces analysis
- The segment that is expected to dominate the market
- Regions that are expected to witness the fastest growth during the forecast period
- Identify the latest developments, market shares, and strategies employed by the major market players
- 3-month analyst support, along with the Market Estimate sheet (in Excel)
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1.1 Market Definition
2. Research Methodology
3. Executive Summary
4. Key Inferences
5. Market Overview
5.1 Current Market Scenario of Microbiome Sequencing Services
5.2 Porter's Five Forces Analysis
5.2.1 Bargaining Power of Suppliers
5.2.2 Bargaining Power of Consumers
5.2.3 Threat of New Entrants
5.2.4 Threat of Substitute Product and Services
5.2.5 Competitive Rivalry within the Industry
6. Drivers, Restraints, Opportunities and Challenges Analysis (DROC)
6.1 Market Drivers
6.1.1 Huge Investment in Microbiome Research
6.1.2 Rise in Demand for NGS Services
6.1.3 Decline in Cost of NGS Sequencing
6.1.4 Surge in Genomic Research and Widening Application Area of Microbiome Sequencing
6.2 Market Restraints
6.2.1 Ethical and Legal Issues Related to Genome Sequencing
6.2.2 Lack of Skilled Technicians for NGS Data Analysis
6.4 Key Challenges
7. Microbiome Sequencing Services Market Segmentation
7.1 By Technology
7.1.1 Sequencing by Litigation (SBL)
7.1.2 Sequencing by Synthesis (SBS)
7.1.3 Short Gun Sequencing
7.1.4 Targeted Gene Sequencing
7.1.5 RNA Sequencing
7.2 By Application
7.2.1 Gastro-Intestinal Diseases
7.2.2 Infectious Diseases
7.2.3 CNS Diseases
7.3 By End User
7.3.1 Research and Academic Institutes
7.3.2 Pharmaceutical and Biotechnology Companies
7.4 By Geography
7.4.1 North America
126.96.36.199 United States
188.8.131.52 United Kingdom
184.108.40.206 Rest Of Europe
220.127.116.11 Australia & New Zealand
18.104.22.168 South Korea
22.214.171.124 Rest of Asia-Pacific
7.4.4 Middle East & Africa
126.96.36.199 South Africa
188.8.131.52 Rest of the Middle East & Africa
7.4.5 South America
184.108.40.206 Rest of South America
8. Competitive Landscape
8.1 Mergers & Acquisition Analysis
8.2 Agreements, Collaborations, and Partnerships
8.3 New Products Launches
9. Microbiome Sequencing Services Market Key Players
9.1 Baseclear B.V.
9.2 Clinical Microbiomics A/S
9.3 Merieux Nutrisciences Corporations
9.5 Microbiome Insights Inc.
9.6 Microbiome Therapeutics, LLC.
9.7 MR DNA
9.8 Second Genome
9.9 Ubiome, Inc.
9.10 Zymo Research Corp.
*List Not Exhaustive
10. Future of the Market