Protein Engineering Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Global Protein Engineering Market Report is Segmented by Product Type (Insulin, Monoclonal Antibodies, Coagulation Factors (Blood Factors + Tissue Plasminogen), Vaccines, Growth Factors (Hormones + Cytokine), and Other Product Types), Technology (Irrational Protein Design and Rational Protein Design), End User (Pharmaceutical and Biotechnology Companies, Academic Institutions, and Contract Research Organizations (CROs)), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Value is Provided in Terms of USD Million for the Above Segments.

Protein Engineering Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

Protein Engineering Market Size

Protein Engineering Market Summary
Study Period 2019 - 2030
Market Size (2025) USD 4.09 Billion
Market Size (2030) USD 8.68 Billion
CAGR (2025 - 2030) 16.24 %
Fastest Growing Market Asia Pacific
Largest Market North America
Market Concentration Medium

Major Players

Protein Engineering Market Major Players

*Disclaimer: Major Players sorted in no particular order

Compare market size and growth of Protein Engineering Market with other markets in Healthcare Industry

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Protein Engineering Market Analysis

The Protein Engineering Market size is estimated at USD 4.09 billion in 2025, and is expected to reach USD 8.68 billion by 2030, at a CAGR of 16.24% during the forecast period (2025-2030).

The propelling factors for the growth of the protein engineering market include the increase in chronic diseases, the rise in demand for targeted therapies, and rising government funding for protein engineering studies. For instance, an article published in April 2023 in the Journal of the Advanced Practitioner in Oncology mentioned the advantages of targeted therapy for improving the response and survival rate among cancer patients. It was observed that the targeted therapy helped oncologists personalize cancer therapy and enhance patient outcomes. Thus, the demand for protein engineering is expected to increase as the use of engineered proteins for targeted drug activation enhances the control of pharmacokinetics and pharmacodynamics and reduces side effects. Such factors are anticipated to propel market growth over the forecast period.

The increasing prevalence of chronic diseases such as cancer fuels the demand for protein-engineered therapies that recognize different molecular targets to regulate the related signaling pathways and kill tumor cells. For instance, according to the 2024 updated data published by the American Cancer Society, around 20 million cancer cases have been diagnosed worldwide, and it is projected to reach 35 million by 2050. Thus, the expected increase in cancer cases is expected to raise the need for effective therapies, which is anticipated to boost the growth of the protein engineering market over the forecast period.

Furthermore, new product launches and collaborative strategies adopted by key players are anticipated to fuel the demand for protein engineering to develop protein-based therapies, propelling market growth. For instance, in April 2023, Swiss Adaptyv Biosystems Sàrl launched two fast-feedback tools that allow cheap, rapid, and miniaturized validation of AI-designed proteins. The new tool is intended to open the way for protein designers to develop new medicines, novel enzymes, and sustainable materials. Similarly, in January 2022, Amgen and Generate Biomedicines entered a research collaboration to discover and create protein therapeutics for five clinical targets across several therapeutic areas and multiple modalities. Hence, the increasing number of strategic activities by key players for efficient protein engineering research helps drive the market's overall growth.

Therefore, factors such as the increasing prevalence of chronic diseases, the growing demand for targeted therapies, and strategic initiatives by key players contribute to market growth. However, the high costs of protein engineering techniques are likely to restrain market growth over the forecast period.

Protein Engineering Industry Overview

The protein engineering market is partially fragmented in nature, and the key players are highly focused on strategies, such as mergers and acquisitions, new product development initiatives, and geographical expansion, to retain their market position. Some of the market players include Amgen Inc., Bruker Corporation, Bio-Rad Laboratories Inc., Agilent Technologies Inc., Eli Lilly and Company, and Merck KGaA.

Protein Engineering Market Leaders

  1. Amgen Inc.

  2. Bio-Rad Laboratories Inc.

  3. Agilent Technologies Inc.

  4. Eli Lilly and Company

  5. Bruker Corporation

  6. *Disclaimer: Major Players sorted in no particular order
Protein Engineering Market Concentration
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Protein Engineering Market News

  • April 2024: Northpond-funded Laboratory for Bioengineering Research and Innovation made an investment with the Wyss Institute for the AmnioX project to facilitate the development of protein-based drugs, thus improving the accessibility of medicines to patients.
  • March 2023: Arzeda collaborated with Takeda to leverage artificial intelligence-based protein design technology to boost the optimization of protein biologics. This collaboration is likely to enhance therapeutic protein development and its products.

Protein Engineering Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Prevalence of Chronic Diseases and Rise in Demand for Targeted Therapies
    • 4.2.2 Rising Government Funding for Protein Engineering Studies
  • 4.3 Market Restraints
    • 4.3.1 High Costs of Protein Engineering Techniques
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Bargaining Power of Suppliers
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Threat of New Entrants
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD)

  • 5.1 By Product Type
    • 5.1.1 Insulin
    • 5.1.2 Monoclonal Antibodies
    • 5.1.3 Coagulation Factors
    • 5.1.4 Vaccines
    • 5.1.5 Growth Factors
    • 5.1.6 Other Product Types
  • 5.2 By Technology
    • 5.2.1 Irrational Protein Design
    • 5.2.2 Rational Protein Design
  • 5.3 By End User
    • 5.3.1 Pharmaceutical and Biotechnology Companies
    • 5.3.2 Academic Institutions
    • 5.3.3 Contract Research Organizations
  • 5.4 Geography
    • 5.4.1 North America
    • 5.4.1.1 United States
    • 5.4.1.2 Canada
    • 5.4.1.3 Mexico
    • 5.4.2 Europe
    • 5.4.2.1 Germany
    • 5.4.2.2 United Kingdom
    • 5.4.2.3 France
    • 5.4.2.4 Italy
    • 5.4.2.5 Spain
    • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
    • 5.4.3.1 China
    • 5.4.3.2 Japan
    • 5.4.3.3 India
    • 5.4.3.4 Australia
    • 5.4.3.5 South Korea
    • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East and Africa
    • 5.4.4.1 GCC
    • 5.4.4.2 South Africa
    • 5.4.4.3 Rest of Middle East and Africa
    • 5.4.5 South America
    • 5.4.5.1 Brazil
    • 5.4.5.2 Argentina
    • 5.4.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Agilent Technologies Inc.
    • 6.1.2 Amgen Inc.
    • 6.1.3 Bruker Corporation
    • 6.1.4 Bio-Rad Laboratories Inc.
    • 6.1.5 Eli Lilly and Company
    • 6.1.6 Merck KGaA
    • 6.1.7 Novo Nordisk AS
    • 6.1.8 PerkinElmer Inc.
    • 6.1.9 Thermo Fisher Scientific Inc.
    • 6.1.10 Waters Corporation
    • 6.1.11 GenScript Biotech Corporation
    • 6.1.12 GE HealthCare
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape Covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Protein Engineering Industry Segmentation

As per the scope of the report, protein engineering is the method in which the structures of proteins are modified to produce the desired properties or synthesize proteins with particular structures. The development of valuable proteins for the treatment of diseases such as cancer enhances their stability and enzymatic activity.

The protein engineering market is segmented by product type, technology, end user, and geography. By product type, the market is segmented into insulin, monoclonal antibodies, coagulation factors, vaccines, growth factors, and other product types. By technology, the market is segmented into irrational protein design and rational protein design. By end users, the market is segmented into pharmaceutical and biotechnology companies, academic institutions, and contract research organizations. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. For each segment, the market size is provided in terms of USD value.

By Product Type Insulin
Monoclonal Antibodies
Coagulation Factors
Vaccines
Growth Factors
Other Product Types
By Technology Irrational Protein Design
Rational Protein Design
By End User Pharmaceutical and Biotechnology Companies
Academic Institutions
Contract Research Organizations
Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
South America Brazil
Argentina
Rest of South America
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Protein Engineering Market Research FAQs

How big is the Protein Engineering Market?

The Protein Engineering Market size is expected to reach USD 4.09 billion in 2025 and grow at a CAGR of 16.24% to reach USD 8.68 billion by 2030.

What is the current Protein Engineering Market size?

In 2025, the Protein Engineering Market size is expected to reach USD 4.09 billion.

Who are the key players in Protein Engineering Market?

Amgen Inc., Bio-Rad Laboratories Inc., Agilent Technologies Inc., Eli Lilly and Company and Bruker Corporation are the major companies operating in the Protein Engineering Market.

Which is the fastest growing region in Protein Engineering Market?

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2025-2030).

Which region has the biggest share in Protein Engineering Market?

In 2025, the North America accounts for the largest market share in Protein Engineering Market.

What years does this Protein Engineering Market cover, and what was the market size in 2024?

In 2024, the Protein Engineering Market size was estimated at USD 3.43 billion. The report covers the Protein Engineering Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Protein Engineering Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.

Protein Engineering Industry Report

Statistics for the 2025 Protein Engineering market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Protein Engineering analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.