Bioprocess Technology Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The report covers Bioprocess Technology Market Trends and the market is segmented by Product (Instruments, Consumables, and Accessories), Application (Recombinant Proteins, Monoclonal Antibodies, Antibiotics, and Other Applications), End-user (Biopharmaceutical Companies, Contract Manufacturing Organizations, Academic Research Institutes, and Other End-users) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market provides the value (in USD million) for the above-mentioned segments.

Bio-Process Technology Market Size

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Bio-process Technology Market Summary
Study Period 2019 - 2029
Market Size (2024) USD 33.60 Billion
Market Size (2029) USD 65.96 Billion
CAGR (2024 - 2029) 14.44 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Bio-process Technology Market Major Players

*Disclaimer: Major Players sorted in no particular order


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Bio-Process Technology Market Analysis

The Bio-process Technology Market size is estimated at USD 33.60 billion in 2024, and is expected to reach USD 65.96 billion by 2029, growing at a CAGR of 14.44% during the forecast period (2024-2029).

  • The COVID-19 pandemic has substantially impacted various markets. The bioprocess technology market faced tremendous disruptions in the initial phase, and its growth was affected. For instance, in August 2022, an article published in the American Pharmaceutical Review stated that the biopharmaceutical manufacturing industry experienced a huge strain on its supply chains. Some of the more significant challenges have occurred in consumable manufacturing goods. Specifically, membrane filters used for sterilization and several other purposes throughout manufacturing bioprocesses were in critically short supply. In addition, single-use systems, separation columns, tubing, raw materials, and components were not readily available. However, this market is expected to gain traction due to the powerful urge to develop vaccines and other biological products. For instance, according to an article published by Poznan University of Economics and Business, biopharma companies undertook new partnerships to discover and deliver vaccines against COVID-19. The pandemic has also enabled the development of several innovative projects related to the COVID-19 vaccine and drug development. Bioprocess technology is highly adopted for vaccine and other biopharmaceutical production.
  • The factors driving the growth of the studied market are expansion in the biopharmaceutical industry and increasing investments in research and development by biotechnology and pharmaceutical companies. The biopharmaceutical sector has deepened its roots across the medical and pharmaceutical industries on account of the transformation of pharmaceutical companies toward biotechnology, creating growth opportunities. For instance, an article published in the Biotechnology Report in July 2022 stated that growing technological developments in biopharmaceutical and pharmaceutical sectors like 3D bioprinting, biosensors, and gene editing, as well as the incorporation of cutting-edge artificial intelligence and virtual and augmented reality, are expected to open growth opportunities by increasing and speeding the production through bioprocessing. Thus, the increasing demand for bio-process technology is driving the growth of the market.
  • Similarly, in October 2022, Oculis SA and European Biotech Acquisition Corp. reported they had entered into a definitive business combination agreement. This agreement is to accelerate the development of Oculis' differentiated ophthalmology pipeline. This product addresses areas of significant medical need, including diabetic macular edema (DME), dry eye disease (DED), and neuro-retina indications, such as glaucoma, affecting growing patient populations. Such agreements and partnerships between different biopharmaceutical companies for developing innovative products are propelling the growth of the market.
  • The increasing research and development are also contributing to the growth of the studied market. For instance, according to the report published by the International Federation of Pharmaceutical Manufacturers & Associations, the annual spending by the biopharmaceutical industry is 8.1 times greater than that of the aerospace and defense industries, 7.2 times more than that of the chemicals industry, and 1.2 times more than that of the software and computer services industry. Of all industrial sectors, the biopharmaceutical industry has consistently invested the most in R&D, even in times of economic turmoil and financial crisis. Similarly, Thermo Fisher Scientific's 2021 annual report reported that the company registered a research and development cost of USD 1,406.00 million in 2021. The R&D expenses grew by 19.05% in 2021. The growing research and development expenses of biopharmaceutical companies are contributing to the development of innovative biopharma products, thereby driving the growth of this market.
  • Thus, the bio-process technology market is expected to witness significant growth over the forecast period due to the expansion in the biopharmaceutical industry and increasing investments in research and development by biotechnology and pharmaceutical companies. However, the high cost of instruments and strict regulations may slow down the growth over the studied period.

Bio-Process Technology Market Trends

Recombinant Protein Segment Expected to Witness Significant Growth Over the Forecast Period.

  • The industrial synthesis of recombinant proteins that are important for therapeutic and preventative purposes depends on the development of effective bioprocessing techniques.
  • Current developments in the various fields of bioprocessing are being used to provide efficient methods for creating recombinant proteins. These include the use of high-throughput devices for effective bioprocess optimization and of disposable systems, continuous upstream processing, continuous chromatography, integrated continuous bioprocessing, quality by design, and process analytical technologies to achieve a quality product with a higher yield.
  • The recombinant protein segment is expected to witness significant growth over the forecast period owing to the growing demand for recombinant proteins for therapeutic applications. Moreover, the recombinant therapeutic proteins provide essential therapies for various diseases, such as diabetes, cancer, infectious diseases, hemophilia, and anemia.
  • Furthermore, recombinant proteins are valuable tools in understanding protein-protein interactions, and the increasing research and development and technological advancements are also expected to drive the growth of this segment.
  • For instance, in October 2022, Larimar Therapeutics Inc. reported issuing a US patent for the protection of CTI-1601. CTI-1601 is a recombinant fusion protein intended to deliver human frataxin to the mitochondria of patients with Friedreich's ataxia who cannot produce enough of this essential protein.
  • Similarly, in February 2021, Sanofi and GSK promulgated the initiation of a new randomized, double-blind, multi-center dose-finding Phase 2 study of their adjuvanted recombinant protein-based COVID-19 vaccine with 720 volunteers. Thus, innovation in healthcare solutions and the development of new recombinant protein-based drugs are driving the segment's growth.
  • The increasing prevalence of chronic diseases like diabetes also boosts the demand for recombinant proteins. For instance, IDF reported that 537 million people (20-79 years old) had diabetes in 2021. This number is expected to increase by 643 million diabetics worldwide by 2030 and 783 million by 2045. With the increase in the diabetic population, the demand for recombinant proteins in the therapeutics segment is likely to show lucrative growth in the coming years, thereby contributing to the development of this segment.
  • Thus, due to the growing demand for recombinant proteins for therapeutic applications and new product launches, the segment is expected to witness significant growth over the forecast period.
Bio-process Technology Market: Research and Development Expenses (in USD million), Global, By Company, 2021

North America Expected to Witness Significant Growth Over the Forecast Period.

  • North America is expected to witness significant growth over the forecast period owing to government support for promoting bioprocess technologies, rising medical expenditure, and developing healthcare infrastructure. In addition, the region has witnessed major collaborative activities with healthcare giants that are extensively investing in R&D in bioprocess technology development.
  • For instance, in March 2022, Stam Biotech raised USD 17 million for its next-generation 3-D printer bioreactor. Similarly, in October 2022, Thermo Fisher Scientific Inc. launched a large-scale cell culture harvesting solution. DynaSpin single-use centrifuge system is a centrifuge that is specifically designed to provide an optimal single-use solution for large-scale cell culture harvesting, to improve and streamline the process by reducing the number of depth filtration cartridges required to complete the harvest process.
  • Furthermore, in May 2022, GOOD Meat signed an exclusive multi-year agreement with ABEC Inc. to design, manufacture, install, and commission the largest known bioreactors for avian and mammalian cell culture. Technologies are focused on helping customers in the biopharmaceutical and pharmaceutical industry to improve the human condition and to provide life-changing drugs to market faster and more efficiently. The collaboration between the companies has leveraged their complementary strengths to develop specific workflows, which bridge the gap between analytical and process solutions.
  • These major biopharmaceutical companies are expanding and boosting the biopharmaceutical segment in North America. For instance, in October 2021, 3M Health Care and Thermo Fisher Scientific collaborated to meet the growing demand for protein-based therapeutics. Manufacturers need advanced technologies and solutions that support reliable and consistent manufacturing processes. The collaboration between 3M and Thermo Fisher also enabled the manufacturers to capture high titer, high cell-density cultures to improve harvesting and clarification and optimize manufacturing capacity, quality, and efficiency.
  • Thus, the technologies, expansions, and investments by these global biopharmaceutical companies are driving the bioprocess technology market in North America.
Bio-process Technology Market: Bio-Process Technology Market - Growth Rate By Region

Bio-Process Technology Industry Overview

The bio-process technology market is fragmented and competitive due to many companies operating globally and regionally. The competitive landscape includes an analysis of a few international as well as local companies which hold market shares and are well known. Some of them are listed below. 

  • F. Hoffmann-La Roche Ltd
  • Sartorius Group
  • Thermo Fisher Scientific Inc.
  • Agilent Technologies Inc.
  • Elitechgroup SpA (Gonotec Gmbh)
  • Advanced Instruments LLC
  • Danaher Corporation
  • Merck KGaA
  • Becton, Dickinson and Company
  • Bio-Rad Laboratories Inc.
  • Lonza Group AG
  • Sartorius Group.

Bio-Process Technology Market Leaders

  1. Thermo Fisher Scientific, Inc.

  2. Agilent Technologies, Inc.

  3. Danaher Corporation

  4. Bio-Rad Laboratories, Inc.

  5. Sartorius Group

*Disclaimer: Major Players sorted in no particular order

Bio-process Technology Market Concentration
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Bio-Process Technology Market News

  • February 2023: Researchers from the Indian Institute of Technology (IIT) Guwahati developed a special 'Protein Toolbox,' which can be used to convert skin cells into heart cells and hence, fix a damaged heart. Known as a 'Recombinant Protein Toolbox,' it comprises six special proteins and can be used to regenerate damaged heart tissues.
  • August 2022: Beckman Coulter Life Sciences announced a partnership with Flownamics to create an automated, online solution for bioprocess culture monitoring and control. This automated integration removes error-prone manual steps while enabling load-and-go sample runs for up to eight bioreactors, GMP compliance with electronic data management, and continuous control of viable cell density, including remote workflows.

Bio-Process Technology Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Expansion in the Biopharmaceutical Industry

      2. 4.2.2 Increasing Investments in Research and Development by Biotechnology and Pharmaceutical Companies

    3. 4.3 Market Restraints

      1. 4.3.1 High Cost of Instruments

      2. 4.3.2 Strict Regulations

    4. 4.4 Industry Attractiveness - Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 5.1 By Product

      1. 5.1.1 Instruments

        1. Bioprocess Analyzers

        2. Osmometers

        3. Bioreactors

        4. Incubators

        5. Other Instruments

      2. 5.1.2 Consumables and Accessories

        1. Culture Media

        2. Reagents

        3. Other Consumables and Acessories

    2. 5.2 By Application

      1. 5.2.1 Recombinant Proteins

      2. 5.2.2 Monoclonal Antibodies

      3. 5.2.3 Antibiotics

      4. 5.2.4 Other Applications

    3. 5.3 By End-User

      1. 5.3.1 Biopharmaceutical Companies

      2. 5.3.2 Contract Manufacturing Organizations

      3. 5.3.3 Academic Research Institute

      4. 5.3.4 Other End-Users

    4. 5.4 Geography

      1. 5.4.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.4.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.4.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.4.4 Middle East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle East and Africa

      5. 5.4.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 F. Hoffmann-La Roche Ltd

      2. 6.1.2 Sartorius Group

      3. 6.1.3 Thermo Fisher Scientific Inc.

      4. 6.1.4 Agilent Technologies Inc.

      5. 6.1.5 ELITechgroup Inc. (Gonotec Gmbh)

      6. 6.1.6 Advanced Instruments LLC

      7. 6.1.7 Danaher Corporation

      8. 6.1.8 Merck KGaA

      9. 6.1.9 Getinge AB

      10. 6.1.10 Bio-Rad Laboratories Inc.

      11. 6.1.11 Lonza Group AG

      12. 6.1.12 Eppendorf AG

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Bio-Process Technology Industry Segmentation

As per the scope of the report, bio-process is a specific process that uses complete living cells or their components to obtain desired products.

The bio-process technology market is segmented by product (instruments (bioprocess analyzers, osmometers, bioreactors, incubators, and other instruments), consumables, and accessories (culture media, reagents, and other consumables and accessories), application (recombinant proteins, monoclonal antibodies, antibiotics, and other applications), end-user (biopharmaceutical companies, contract manufacturing organizations, academic research institutes, and other end-users) and geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Product
Bioprocess Analyzers
Other Instruments
Consumables and Accessories
Culture Media
Other Consumables and Acessories
By Application
Recombinant Proteins
Monoclonal Antibodies
Other Applications
By End-User
Biopharmaceutical Companies
Contract Manufacturing Organizations
Academic Research Institute
Other End-Users
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle East and Africa
South Africa
Rest of Middle East and Africa
South America
Rest of South America
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Bio-Process Technology Market Research FAQs

The Bio-process Technology Market size is expected to reach USD 33.60 billion in 2024 and grow at a CAGR of 14.44% to reach USD 65.96 billion by 2029.

In 2024, the Bio-process Technology Market size is expected to reach USD 33.60 billion.

Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., Danaher Corporation, Bio-Rad Laboratories, Inc. and Sartorius Group are the major companies operating in the Bio-process Technology Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Bio-process Technology Market.

In 2023, the Bio-process Technology Market size was estimated at USD 29.36 billion. The report covers the Bio-process Technology Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Bio-process Technology Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Bioprocess Technology Industry Report

Statistics for the 2024 Bioprocess Technology market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Bioprocess Technology analysis includes a market forecast outlook 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Bioprocess Technology Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)