Biomedical Refrigerator And Freezer Market Size and Share
Biomedical Refrigerator And Freezer Market Analysis by Mordor Intelligence
The Biomedical refrigerator & freezer market is valued at USD 4.54 billion in 2025 and is forecast to reach USD 6.04 billion by 2030, expanding at a 6.4% CAGR. This growth reflects rising investments in cell and gene therapies that rely on ultra-precise temperature control, stricter global vaccine‐storage mandates, and an accelerating shift toward decentralized clinical trials that require portable, IoT-enabled cold-chain assets. Compressor technology still underpins most installed capacity, yet sustainability regulations are propelling rapid adoption of magnetic refrigeration and other refrigerant-free approaches. Supply-chain resilience is a recurring theme: helium scarcity constrains cryogenic capacity, while semiconductor shortages lengthen lead times for smart freezers. As a result, buyers now evaluate vendors not only on cooling performance but also on component traceability, remote monitoring, and predictive-maintenance features that limit downtime.
Key Report Takeaways
- By product type, laboratory refrigerators captured 23.4% of the Biomedical refrigerator & freezer market share in 2024, while ultra-low-temperature freezers are projected to expand at a 10.6% CAGR through 2030.
- By technology, compressor-based systems retained a 54.2% share, and magnetic refrigeration is forecast to post the fastest 46.9% CAGR between 2025 and 2030.
- By end user, hospitals led with 33.4% revenue share in 2024, whereas biobanks are set to grow at a 10.7% CAGR to 2030.
- By geography, North America held a 27.3% share of the Biomedical refrigerator and freezer market in 2024, and Asia Pacific remains the fastest-growing region, with a 6.9% CAGR.
Global Biomedical Refrigerator And Freezer Market Trends and Insights
Drivers Impact Analysis
Driver | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
---|---|---|---|
Growing Burden Of Chronic Diseases | +1.20% | Global, with concentration in North America & Europe | Long term (≥ 4 years) |
Increasing Demand For Organ Transplantation & Cell and Gene Therapy Storage | +1.80% | North America & EU core, expanding to APAC | Medium term (2-4 years) |
Expansion Of Blood Banks & Biobanks In Emerging Markets | +0.90% | APAC core, spill-over to MEA and Latin America | Long term (≥ 4 years) |
Regulatory Mandates For Temperature-Sensitive Vaccine Logistics | +1.10% | Global | Short term (≤ 2 years) |
Decentralized Clinical Trials Driving Portable, IoT-Enabled Cold Chain | +0.70% | North America & EU, early adoption in APAC | Medium term (2-4 years) |
Adoption Of Magnetic Refrigeration For Green, Energy-Efficient Labs | +0.50% | EU core, expanding to North America | Long term (≥ 4 years) |
Source: Mordor Intelligence
Growing Burden of Chronic Diseases
More than 537 million adults live with diabetes, and many require insulin that must remain between 2 °C and 8 °C.[1]World Health Organization, “Diabetes,” who.int This single-therapy storage requirement alone keeps a continuous stream of orders flowing into the Biomedical refrigerator & freezer market. Government-sponsored non-communicable-disease programs are funding new pharmaceutical-grade cold rooms, especially across India and Southeast Asia, while European hospitals are upgrading to multi-zone cabinets that can segregate biologics, vaccines, and blood products without expanding floor space. Oncology wards are another growth node; a single batch of temperature-excursion-sensitive monoclonal antibodies can exceed USD 70,000 in replacement cost, which heightens willingness to pay for redundant compressors, battery backups, and 24/7 cloud telemetry.
Increasing Demand for Organ Transplantation & Cell and Gene Therapy Storage
CAR-T, CRISPR-edited cell products, and ex-vivo gene therapies must often remain below -150 °C from manufacturing to bedside. Fusion-style freezers that forgo liquid nitrogen while maintaining -165 °C are gaining traction because they ease lab safety checks and shrink operating expenses. Logistics chains now embed GPS and continuous-temperature data streams so that a transplant coordinator can verify, in real time, whether a donor heart remains within its mandated 2 °C to 8 °C envelope during cross-country flights. Each incremental regulatory guideline—such as the FDA’s 2024 cell-therapy manufacturing guidance—elevates the equipment specification baseline and accelerates replacement of legacy freezers that cannot document uniformity or rapid temperature recovery.
Expansion of Blood Banks & Biobanks in Emerging Markets
Large-scale facilities such as Brazil’s Fiocruz Biodiversity and Health Biobank illustrate how middle-income economies are leapfrogging straight to high-specification, IoT-enabled storage.[3]Frontiers Editors, “Fiocruz Biodiversity and Health Biobank,” frontiersin.org Indonesia’s Medela Potentia attracted a USD 12 million IFC loan partly to purchase modular ULT banks that can expand capacity without lengthy construction permits. Biobanks now double as genomic-data repositories, so cabinets must integrate barcode readers, RFID antennas, and secure cloud connections. To mitigate power outages in rural areas, many units ship with 24-hour battery packs and solar inverters.
Regulatory Mandates for Temperature-Sensitive Vaccine Logistics
The CDC’s latest Vaccine Storage and Handling Toolkit removes exemptions for household fridges, obligating clinics to adopt purpose-built biomedical models with continuous digital logging. USP <659> codified “controlled cold” (+2 °C to +15 °C) and excursion limits, prompting pharmacies to recalibrate procedures and invest in alarm-forwarding systems that dispatch SMS alerts when thresholds approach. The mRNA vaccine boom has further normalized –80 °C storage, raising base-line specifications across the entire Biomedical refrigerator & freezer market. Off-grid regions rely on solar direct-drive units capable of 93-hour holdover at 43 °C ambient, shrinking cold-chain gaps in sub-Saharan Africa.
Restraints Impact Analysis
Restraint | (~) % Impact on CAGR Forecast | Geographic Relevance | Impact Timeline |
---|---|---|---|
High Capital & Maintenance Costs | -1.40% | Global, particularly impacting emerging markets | Long term (≥ 4 years) |
Stringent Phase-Out Of High-GWP Refrigerants | -0.80% | EU core, expanding to North America & APAC | Medium term (2-4 years) |
Global Helium Shortage Limiting Cryogenic Freezer Uptake | -0.60% | Global, with acute impact in North America & Europe | Short term (≤ 2 years) |
Chip-Set Supply Crunch Delaying Smart-Freezer Roll-Outs | -0.40% | Global, with concentration in North America & APAC | Short term (≤ 2 years) |
Source: Mordor Intelligence
High Capital & Maintenance Costs
A state-of-the-art ULT freezer can list for USD 50,000, and annual service contracts often reach 15% of the purchase price. Electricity adds further burden: one 80 °C box may consume 15 kWh per day, equaling USD 1,500 in yearly energy expense at average US commercial rates. Smaller clinics and NGOs routinely defer purchases or opt for leasing to avoid upfront hits to capital budgets. Import tariffs compound the challenge in Africa and parts of South Asia, where duties can exceed 15% on medical equipment. These factors lengthen replacement cycles and slow penetration of advanced IoT-enabled units, especially in price-sensitive geographies.
Global Helium Shortage Limiting Cryogenic Freezer Uptake
Helium spot prices quadrupled between 2022 and 2024 after outages at US and Russian refining plants. Many laboratories now ration helium for MRI magnets, leaving little for –150 °C cryogenic freezers.[2]IOP Publishing, “Cryogenic Freezers for Cell Therapy,” iopscience.iop.org Some sites have mothballed research protocols that depend on sub-120 °C storage, temporarily shifting samples into –86 °C cabinets that, while acceptable for weeks, risk viability losses over longer horizons. Vendors fast-track helium-free designs, yet scaling alternative technologies still requires multi-year manufacturing investments.
Segment Analysis
By Product Type: Laboratory Refrigerators Lead Amid ULT Surge
Laboratory refrigerators captured the largest slice of the Biomedical refrigerator & freezer market in 2024 at 23.4% because virtually every clinical, academic, and industrial health facility must store reagents, vaccines, or patient samples within the 2 °C–8 °C band. These units now ship with microprocessor controllers, door-opening sensors, and fan-assisted airflow that keeps temperature variance below ±1 °C. At the same time, the ULT category is growing at a 10.6% CAGR as biobanks, contract-development organizations, and hospital pathology labs expand cryogenic capacity for cell lines, stem cells, and mRNA therapeutics. ULT freezers already account for USD 1.12 billion of the Biomedical refrigerator & freezer market size, and their share will climb because regulatory filings for ATMPs require validated sub--80 °C storage audits.
Plasma freezers and blood bank refrigerators sustain mid-single-digit growth by replacing aging stock in transfusion centers, whereas shock freezers—niche devices that drop from ambient to –40 °C within 10 minutes—are finding new demand in advanced oncology research protocols. Manufacturers increasingly bundle cloud dashboards and service-level agreements that guarantee four-hour on-site technician response, a feature especially valued by high-throughput COVID-19 genomic surveillance labs.
Note: Segment shares of all individual segments available upon report purchase
By Technology: Compressor Systems Dominate While Magnetic Refrigeration Disrupts
Conventional compressor architectures remain the backbone with 54.2% share because their maintenance ecosystem is mature and replacement parts are ubiquitous. The design’s decades-long track record reassures risk-averse hospital engineers, preserving strong reorder momentum even as greener options emerge. However, magnetic refrigeration demonstrates a 46.9% CAGR thanks to 20%–30% lower electricity draw and elimination of high-GWP refrigerants. Early adopters include central labs in Denmark piloting 600-liter pilot units that meet ISO 20387 biobank accreditation without hydrofluorocarbons. Absorption and Stirling engines occupy specific niches: absorption excels in off-grid vaccine programmes due to silent, battery-free operation, while Stirling engines enable precise temperature control with very low vibration, protecting delicate electron-microscopy samples.
Beyond mechanical innovation, software overlays are universal. Vendors now ship over-the-air firmware updates to patch cybersecurity vulnerabilities, and AI algorithms forecast compressor wear, prompting preemptive part replacement. Such digital layers turn hardware sales into subscription services, lengthening customer stickiness within the Biomedical refrigerator & freezer market.
By End User: Hospitals Lead While Biobanks Drive Growth
Hospitals hold 33.4% of 2024 revenue because inpatient pharmacies, blood banks, and clinical-trial pharmacies all rely on tightly managed cold rooms. A tertiary medical center may operate more than 200 individual cabinets spread across wards, ICU wings, and OR suites. Pharmacy accreditation bodies now audit continuous-temperature records, pushing hospital procurement toward units with integrated cloud gateways and battery-backed memory modules.
Biobanks, however, deliver a 10.7% CAGR through 2030 as precision-medicine initiatives chase vast repositories of genomic samples. National-scale projects like Genome India plan to bank several million biospecimens, fueling multi-million-dollar tenders for modular rack-mount ULT clusters. Academic labs and pharma R&D groups continue to expand ULT fleets, though they increasingly outsource overflow storage to commercial biorepository operators that guarantee 99.99% uptime under ISO 9001 and ISO 20387 certification. Diagnostic and IVF centers represent smaller but rising contributors, especially in Asia Pacific, where fertility-preservation demand lifts purchases of –150 °C cryogenic canisters.

Note: Segment shares of all individual segments available upon report purchase
Geography Analysis
North America generated 27.3% of worldwide revenue in 2024. FDA quality-management reforms, effective February 2026, require device makers to harmonize with ISO 13485; forward-thinking hospitals and CROs are pre-emptively replacing legacy stock to avoid qualification headaches. The United States also houses leading biopharma clusters that consume significant cryogenic capacity; Thermo Fisher’s USD 2 billion multi-site investment underscores confidence in sustained demand. Semiconductor shortages remain a downside risk; nearly 80% of manufacturers report 12-month lead times for Wi-Fi-enabled temperature-loggers, hampering rollouts of smart cabinets.
Asia Pacific records the fastest 6.9% CAGR on the strength of health-system capital spending and a thriving clinical-research outsourcing sector. China scales local biomanufacturing, India expands transfusion services, while Indonesia receives multilateral funding to install rural vaccine fridges with solar-direct-drive compressors. Regional governments often bundle cold-chain upgrades with broader infectious-disease preparedness, effectively underwriting initial equipment procurement. Domestic manufacturing is ramping: Chinese vendors now export ENERGY STAR-certified ULT models across ASEAN, intensifying price competition but also driving product innovation.
Europe grows steadily on the back of stringent environmental policies. EU F-gas phase-down regulations discourage high-GWP refrigerants, pushing labs toward natural-refrigerant compressors or emerging magnetocaloric systems. Cold Chain Technologies opened a Netherlands plant with an A+++ energy rating, allowing same-day distributionI'll help you with a comprehensive analysis of the Biomedical Refrigerator & Freezer market. Let me use the available tools to gather more information and provide you with a well-structured analysis.

Competitive Landscape
Competitive Landscape
Biomedical Refrigerator And Freezer Industry Leaders
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Arctiko
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PHC Corporations
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Haier Biomedical
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Philips Kirsch GmbH
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Terumo Corporation
- *Disclaimer: Major Players sorted in no particular order

Recent Industry Developments
- April 2025: Thermo Fisher Scientific committed USD 2 billion to US manufacturing and R&D over four years.
- March 2025: Cold Chain Technologies set up new Asia Pacific distribution and service hubs.
- January 2025: Cryoport introduced the HV3 cryogenic shipping system for advanced therapies.
- June 2024: Haier Biomedical launched the wide-neck CryoBio cryogenic series with IoT controls.
Global Biomedical Refrigerator And Freezer Market Report Scope
As per the scope, a biomedical refrigerator and freezer are designed in such a way that they can store samples of biological origin at the lowest temperatures. The Biomedical Refrigerator and Freezer Market is segmented by product type (plasma freezers, blood bank refrigerators, laboratory refrigerators, laboratory freezers, and others), end user (hospitals and clinics, biobanks, and others), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across the major regions globally. The report offers the values in (USD million) for the above segments.
By Product Type | Plasma Freezers | ||
Blood Bank Refrigerators | |||
Laboratory Refrigerators | |||
Laboratory Freezers | |||
Ultra-Low Temperature Freezers | |||
Shock Freezers | |||
Pharmaceutical Refrigerators | |||
Others | |||
By Refrigeration Technology | Compressor-based | ||
Absorption/Adsorption | |||
Magnetic Refrigeration | |||
Stirling Engine | |||
By End User | Hospitals & Clinics | ||
Blood Banks | |||
Biobanks & Gene Banks | |||
Pharma & Biotech Companies | |||
Academic & Research Labs | |||
Others (Diagnostic / IVF Centers) | |||
By Geography | North America | United States | |
Canada | |||
Mexico | |||
Europe | Germany | ||
United Kingdom | |||
France | |||
Italy | |||
Spain | |||
Rest of Europe | |||
Asia Pacific | China | ||
Japan | |||
India | |||
South Korea | |||
Australia | |||
Rest of Asia Pacific | |||
Middle East & Africa | GCC | ||
South Africa | |||
Rest of Middle East & Africa | |||
South America | Brazil | ||
Argentina | |||
Rest of South America |
Plasma Freezers |
Blood Bank Refrigerators |
Laboratory Refrigerators |
Laboratory Freezers |
Ultra-Low Temperature Freezers |
Shock Freezers |
Pharmaceutical Refrigerators |
Others |
Compressor-based |
Absorption/Adsorption |
Magnetic Refrigeration |
Stirling Engine |
Hospitals & Clinics |
Blood Banks |
Biobanks & Gene Banks |
Pharma & Biotech Companies |
Academic & Research Labs |
Others (Diagnostic / IVF Centers) |
North America | United States |
Canada | |
Mexico | |
Europe | Germany |
United Kingdom | |
France | |
Italy | |
Spain | |
Rest of Europe | |
Asia Pacific | China |
Japan | |
India | |
South Korea | |
Australia | |
Rest of Asia Pacific | |
Middle East & Africa | GCC |
South Africa | |
Rest of Middle East & Africa | |
South America | Brazil |
Argentina | |
Rest of South America |
Key Questions Answered in the Report
What is driving the current growth of the Biomedical refrigerator & freezer market?
The strongest tailwinds are the surge of cell and gene therapies that need ultra-low temperatures, tighter global vaccine-storage rules, and hospital investments in IoT-enabled units for real-time monitoring—all combining to support a 6.4% CAGR through 2030.
How large is the Biomedical refrigerator & freezer market today, and what is its outlook?
The Biomedical refrigerator & freezer market stands at USD 4.54 billion in 2025 and is projected to reach USD 6.04 billion by 2030 as precision-medicine pipelines and decentralized clinical trials expand cold-chain nodes worldwide.
Why are magnetic-refrigeration systems gaining traction?
Labs in Europe and North America are adopting magnetocaloric technology because it eliminates high-GWP refrigerants and lowers power draw by up to 30%, helping facilities meet increasingly strict sustainability targets without sacrificing –80 °C performance.
Which end-user segment is growing fastest?
Biobanks record a 10.7% CAGR to 2030, propelled by precision-medicine initiatives and pandemic-preparedness plans that require long-term, ultra-low-temperature storage for tissue, plasma, and genomic samples.
How are supply-chain disruptions affecting equipment availability?
Semiconductor shortages are extending lead times for smart cabinets to 12 months or more, while a global helium crunch limits the roll-out of –150 °C cryogenic freezers, pushing buyers to consider helium-free Stirling or magnetic alternatives.
Page last updated on: June 29, 2025