Adherence Packaging Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The adherence packing market is segmented by Material (Plastic, Paper and Paperboard, and Aluminium), Type (Unit-dose Packaging, Multi-dose Packaging), Packaging Type (Blisters, Pouches), End-User Industries (Pharmacies, Hospitals) and Geography.

Market Snapshot

AP_Image cagr
Study Period: 2018 - 2026
Base Year: 2021
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 5.9 %

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Market Overview

The adherence packing market is expected to register a CAGR of 5.9% over the forecast period from 2020 to 2025. Blister packaging helps prevent children from accidental medicine consumption. Regarding the incidence of hospitalization, with opioid poisoning among children, the CDC reported that, during 2007-2011, for every 500 adults treated with buprenorphine, one child was hospitalized. Hence, the active transition toward blister packaging by 2012 saw a 65% drop in emergency department visits.

  • Also, more than 80% of emergency department (ED) visits, in line with medication poisoning among children under the age of 12 years, can be attributed to unsupervised children taking medications independently. Additionally, nearly 10% of ED visits are primarily due to medication errors, as per the National Electronic Injury Surveillance System-Cooperative Adverse Event Surveillance System (NEISS-CADES) project. The reduction of dosing intervals is crucial for patients who develop the need to alleviate the anxiety of anticipated pain between dosing intervals. Therefore, adherence packaging offers dosage reminders for patients and caregivers, thus, reducing the likelihood of underdosing or overdosing.
  • Furthermore, recent developments about the digital capture of dispense events via near field communication (NFC) or radio frequency identification (RFID) are being incorporated into packaging for verification, on similar lines. The unit-dose blisters allow passive, active, and interactive features to combat the opioid epidemic and improve pharmaceutical safety. Passive elements refer to graphic or text reminders and warnings. Dynamic features use electronics for reminders or alarms, in case of a shortened dosing period. Moreover, interactive features enable the patients to respond to prompts from the packaging, in the form of recording of doses and timing, to curb the addictive behavior.
  • The recent event, Pharmapack Europe, 2020, highlighted the importance of digital value-added medicines, increased need for waste management, device development in biologics, and blockchain. It went further to address the role of blister packaging in adherence packaging. However, a study on adherence in people with mental disorders across India suggested that the primary cause of non-compliance is due to the high cost of medicines. Pharmaceutical manufacturers can affect the prices of medicine by delivering safe and effective drugs at lower costs. Although the pharma packaging industry cannot be directly associated with the rising cost of products for the end-users, at an operational level, the capital equipment purchases may assist the costs indirectly.
  • Meanwhile, on the vendor front, Acute Technology, a tech-based medication adherence provider, has been stressing upon the use of Hydra Communications Gateway. This may enable the usage of a smartphone to facilitate the electronic monitoring of dosages. This effectively addresses the problem of a lack of control of the medication supplied through weekly medicine trays. However, pharmaceutical companies taking center stage in the COVID-19 fight, such as Gilead and Eli Lilly, are seeing positive growth on the stock market and a new burst of innovation in the infectious disease landscape as the race for treatment approval for a COVID-19 therapy taking off which expected to boost the adherence packaging market significantly.

Scope of the Report

Compliance packaging, also known as adherence packaging, refers to the type of packaging that eases the patients’ adherence to their drug regimen. The arrangement of drugs, by specifying drugs by dose, days of the week, and time of day, makes it easier for patients to take the right medicines at the right time.

By Material
Plastic (PE, PET, PVC, and PP)
Paper and Paperboard
By Type
Unit-dose Packaging
Multi-dose Packaging
By Packaging Type
Other Packaging Types
By End-User Industry
Other End-user Industries
North America
Asia Pacific
Latin America
Middle East and Africa

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Key Market Trends

Multi-Dose Packaging is Expected to Witness Significant Growth

  • The importance of medication adherence and the benefits of synchronizing those medications have led to the development of multi-dose packages. The benefits of multi-dose blister cards include setting up dosage time to eliminate confusion, more natural self-medication, and cutting down the number of visits to the pharmacy per month. Multiple studies have proven improved adherence and health outcomes, combined with multimed blister packs and medication therapy management (MTM).
  • A survey conducted by Omnicell suggested that patients assigned to the multimed packaging groups accounted for medication adherence rates of 80% initially, and they even accounted for 90% adherence rates by the completion of the trial. Alternatively, patients assigned to the pill bottle-only group accounted for an adherence rate of 56%. Omnicell offered multimed blister cards to Holyoke Health Center. The health center used Omnicell’s SureMed+, a seven-day, four-time pass, cold-seal, bi-fold card.
  • In early 2019, Buffalo Pharmacies offered multimed blister card packaging to patients, caregivers, and pharmacists, for the smooth management of complex medication regimens. To increase patient adherence to medications, the company selected the SureMed packaging system from Omnicell. The system provided perforated cards to offer a level of convenience for the patients. And, the ability to ‘tear-off’ a dose for on-the-go consumption served as a significant advantage, in terms of adherence packaging.
  • Furthermore, e-commerce players are observed to have been expanding convenience, compliance, and customized healthcare packaging for the elderly population. Last year’s Amazon’s purchase of the online pharmacy, PillPack, suggests the need for the online delivery of medication, thus, indicating the potential for multimed packs to be demanded. The multi-dose packaging, amid the COVID-19 outbreak, has to ensure a reduced amount of ‘touchpoints’ for the processing of a patient’s prescriptions, while avoiding confusion associated with self-medicating.
Adherence Packaging Market

North America Dominates the Market and Expected to do Same in the Forecast Period

  • The North American region is developed with prosperous economies, aging population segments, and advanced medical delivery systems. Still, the countries vary measurably in population size, healthcare spending intensities, aggregate gross domestic product (GDP) levels, and the structure of health insurance plans. With advanced primary medical community, extensive medical and life science research activities, high healthcare spending intensity, and large pharmaceutical and medical supply and device industries, the United States accounts for one of the world's largest geographical markets for adherence packaging products.
  • In August 2019, the Healthcare Compliance Packaging Council (HCPC) supported the US Congress' and the FDA's plan to enhance packaging development to reduce opioid misuse among patients. The development of unit-dose blister packaging has successfully aided the CDC's and FDA's plans to limit the initial prescriptions for acute pain by providing pre-packed doses. Unit-dose packaging is gaining momentum in blister packaging, as it offers advantages, such as decreased dosing intervals for some of the chronic care patients.
  • In early 2019, PCI Pharma Services announced the launch of child-resistant blister packaging. Its investments across US facilities were the result of the new opioid legislation in the United States. The US DEA Schedule I-V controlled substances for both commercial prescription medicines and investigational clinical trials that were being supported by the company. Since then, the company's significant investments have been to expand the existing capacity for blister packaging to meet the stringent requirements of the regulatory authorities. Thus, the company can now produce more than five billion units of blister packs annually.
  • Also, as per Parata Systems, non -adherence to medication, on average, costs USD 300 billion/year in the United States. Pouch packaging has reduced the cost of care and improved patient outcomes. With the growing presence of strip packaging in the market, patient awareness is expected to pressurize pharmacies without proper packaging to be left behind. The company launched Parata PASSTM 36, targeting pharmacies. Parata Systems, being a provider of pharmacy automation systems, including vial -filling, adherence packaging, and workflow and patient experience solutions, launched a pouch packager, named PASSTM 36.

Competitive Landscape

The global adherence packaging market is moderately competitive and consists of a few significant players. Companies like Cardinal Health, Inc., WestRock Company, Omnicell Inc., Parata Systems LLC, and Keystone Folding Box Co., among others, hold a substantial market share in the Adherence Packaging market. The market various is also witnessing multiple product launches and partnerships.

  • February 2020 - Parata Systems launched a new pouch packager, the PASS 36. The Parata PASS 36 with a small footprint and low cost now provides pharmacies ready to begin their adherence packaging program with automation designed to handle smaller volumes while promising the scalability a growing business needs.
  • January 2020 - Omnicell, Inc. showcased the latest advancements to its medication management portfolio at the Arab Health Exhibition and Congress, Dubai. Omnicell’s platform of automation solutions supports medication safety on patient wards; provides more efficient medication storage, dispensing, and filling in the hospital pharmacy; and helps improve medication adherence through automated multimed packaging solutions for an outpatient pharmacy, which can result in better patient outcomes.

Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Industry Supply Chain Analysis

    3. 4.3 Industry Attractiveness - Porter's Five Forces Analysis

      1. 4.3.1 Bargaining Power of Suppliers

      2. 4.3.2 Bargaining Power of Consumers

      3. 4.3.3 Threat of New Entrants

      4. 4.3.4 Threat of Substitute Products

      5. 4.3.5 Intensity of Competitive Rivalry


    1. 5.1 Market Drivers

      1. 5.1.1 Rise in Need to Minimize Medication Wastage

      2. 5.1.2 High Rate of Medication Non-Adherence

    2. 5.2 Market Challenges

      1. 5.2.1 High Installation and Maintenance Costs of Automated Systems

      2. 5.2.2 Lack of Awareness Regarding Medication Adherence Packaging

    3. 5.3 Market Opportunties




    1. 8.1 By Material

      1. 8.1.1 Plastic (PE, PET, PVC, and PP)

      2. 8.1.2 Paper and Paperboard

      3. 8.1.3 Aluminum

    2. 8.2 By Type

      1. 8.2.1 Unit-dose Packaging

      2. 8.2.2 Multi-dose Packaging

    3. 8.3 By Packaging Type

      1. 8.3.1 Blisters

      2. 8.3.2 Pouches

      3. 8.3.3 Other Packaging Types

    4. 8.4 By End-User Industry

      1. 8.4.1 Pharmacies

      2. 8.4.2 Hospitals

      3. 8.4.3 Other End-user Industries

    5. 8.5 Geography

      1. 8.5.1 North America

      2. 8.5.2 Europe

      3. 8.5.3 Asia Pacific

      4. 8.5.4 Latin America

      5. 8.5.5 Middle East and Africa


    1. 9.1 Company Profiles

      1. 9.1.1 Westrock Company

      2. 9.1.2 Keystone Folding Box Co.

      3. 9.1.3 Cardinal Health Inc

      4. 9.1.4 Omnicell Inc.

      5. 9.1.5 Jones Healthcare Group

      6. 9.1.6 Drug Package LLC

      7. 9.1.7 Parata Systems LLC

    2. *List Not Exhaustive

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Frequently Asked Questions

The Adherence Packaging Market market is studied from 2018 - 2026.

The Adherence Packaging Market is growing at a CAGR of 5.9% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

Westrock Company, Omnicell Inc., Cardinal Health, Inc., Parata Systems LLC, Keystone Folding Box Co. are the major companies operating in Adherence Packaging Market.

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