Solvent Evaporation Market Size & Share Analysis - Growth Trends & Forecasts (2023 - 2028)

Solvent Evaporation Market is segmented By Type (Nitrogen Blowdown Evaporators, Rotary Evaporators, Centrifugal Evaporators, and Spiral Air Flow Evaporators), End User (Research and Academic Institutes, Diagnostic Laboratories, and Pharmaceutical and Biopharmaceutical Industry), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The market provides the value (in USD million) for the above-mentioned segments.

Solvent Evaporation Market Size

Solvent Evaporation Market Size
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Study Period 2018 - 2028
Base Year For Estimation 2022
Forecast Data Period 2023 - 2028
CAGR 6.50 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players


*Disclaimer: Major Players sorted in no particular order


Need a report that reflects how COVID-19 has impacted this market and its growth?

Solvent Evaporation Market Analysis

The solvent evaporation market is expected to register a CAGR of 6.5% during the forecast period.

The COVID-19 outbreak has had a significant negative impact on the healthcare business and has badly impacted the entire supply chain. Regarding the market studied, the solvent evaporation technique was used in some instances to understand the drug efficacy for COVID-19. For instance, as per the article published in March 2022 titled, 'Study results in three new co-amorphous drug systems with great anti-COVID-19 potential,' in China, MAR has a long history of use in the treatment of chronic enteritis and hepatitis. MAR was used in COVID-19 therapy at the beginning of 2020 in combination with antiviral drugs such as ritonavir, lopinavir, or abidol. To understand the efficacy of these drugs, co-amorphous systems were developed using the solvent evaporation method. Hence, with such effective uses of solvent evaporation, the market witnessed a positive impact of the COVID-19 pandemic.

The growth of the market is attributed to increasing R&D expenditure, a growing development of large-molecule biopharmaceuticals, and increasing demand for pure samples in the end-use markets. For instance, during the year 2021, major pharmaceutical companies spent a considerable amount on research and development as a result of the rising need for novel therapeutics. Companies such as Pfizer, Roche, Merck & Co., and Johnson and Johnson have spent almost 20% to 25% of their total revenue on R&D. This high spending is contributing to the market growth.

The solvent evaporation technique is widely used in sample preparation across pharmaceutical industries. Thus, the increasing use of this technology, coupled with growing development in the novel drug, is propelling the market. Moreover, the benefits of solvent evaporation techniques compared to other preparation methods, such as sonication and spray drying, are widely used in microencapsulation and floating microspheres. Furthermore, the rising demand to obtain the highest purity in drugs with rising demand for laboratory automation is likely to fuel the solvent evaporation market.

Solvent Evaporation Market Trends

This section covers the major market trends shaping the Solvent Evaporation Market according to our research experts:

Rotary Evaporator in Solvent Evaporation Market is Estimated to Witness a Healthy Growth in Future.

A rotary evaporator is estimated to witness healthy growth in the future due to the increasing demand for pure samples in the pharmaceutical and biotechnology industries and its wide application in food technology, environmental engineering, and diagnosing laboratories. These rotary evaporator plays a major role in the efficient extraction of solvent through evaporation which is an important step in developing pure samples in several industries. The increasing R&D expenditures worldwide may also propel the solvent evaporation market due to several benefits associated with this technique. For instance, as per the 2020 report published by India Brand Equity Foundation (IBEF), Indian pharma companies spent around 8.5% of their revenue on research and development during 2020. With high R&D, new technologies in solvent evaporation may evolve which is believed to fuel the market growth.

In the search for novel therapies, rotary evaporation is utilized for synthesis, development, sample preparation, solvent recycling, and scale-up production. The technological advancements in the rotary evaporators are enabling ease of pharma production. For instance, high automation is one of the leading features of rotary evaporators that can offer reliability and convenience in the pharma R&D laboratory. For instance, BUCHI India Pvt. Ltd, a company operating in this business provides a Rotavapor R-300 rotary evaporator which is highly advanced. This evaporator can provide a sample throughput of 4 to 96 samples per batch with sample amounts ranging from 1 to 500 ml per sample.

Hence, with the availability of technologically advanced rotary evaporators and the rising need for the same across the pharma industry, the segment is expected to witness strong growth over the forecast period.


North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period

North America is expected to hold a significant market share in the global solvent evaporation market due to increasing R&D expenditure, rising growth in biosimilars and generics markets, increasing healthcare expenditure, and the presence of a well-established healthcare infrastructure. Moreover, the United States is the largest market for biopharmaceuticals. It is the world leader in biopharmaceuticals R&D. As per the Pharmaceuticals Research and Manufacturers Association (PhRMA), the United States holds the most R&D centers worldwide in the pharmaceutical sector. As per the PhRMA Annual Membership Survey conducted in 2022, the United States spent approximately USD 102 billion during the year 2021 which is 8.7% more than that of the year 2020. Thus, the increasing number of pharmaceutical manufacturers is expected to boost the demand for this technique and further drive the market studied in the North American region.

Some of the key companies operating in the solvent evaporation business across North American countries include Labconco Corporation, Biotage AB, Organomation Associates, Inc., and Raykol, among others. With the high adoption of the technology in the United States and Canada, solvent evaporation equipment is becoming more advanced which is fueling the market growth in the region.

Hence, with the above-mentioned factors, North America is expected to dominate the global solvent evaporation market over the forecast period.

Solvent Evaporation Market Growth

Solvent Evaporation Industry Overview

The solvent evaporation market is moderately competitive and consists of several major players. Some of the companies in this market include Biotage, Buchi Labortechnik AG, Heidolph Instruments GmbH & CO. KG, Labconco, Yamato Scientific Co., Porvair PLC, KNF Neuberger Inc., and Steroglass Srl.

Solvent Evaporation Market Leaders

  1. Biotage

  2. Buchi Labortechnik AG

  3. Heidolph Instruments GmbH & CO. KG

  4. Labconco

  5. Yamato Scientific Co.

*Disclaimer: Major Players sorted in no particular order


Solvent Evaporation Market News

  • In February 2022, Biotage announced the launch of a sophisticated well plate evaporator, the TurboVap 96 Dual, a second-generation system with two separate, and independently controlled evaporation compartments, building upon the reputable foundation of the Biotage TurboVap product line.
  • In January 2021, Porvair Sciences has launched a new second-generation model of its Ultravap Mistral - an automation-ready sample evaporator that offers throughput advantages to laboratories looking to optimize and accelerate sample preparation.

Solvent Evaporation Market Report - Table of Contents


    1. 1.1 Study Assumptions and Market Definition

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increasing R&D Expenditure

      2. 4.2.2 Growing Development of Large-molecule Biopharmaceuticals

      3. 4.2.3 Increasing Demand for Pure Samples in the End-user Markets

    3. 4.3 Market Restraints

      1. 4.3.1 High Manufacturing and Product Cost

    4. 4.4 Industry Attractiveness - Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size - Value in USD million)

    1. 5.1 By Type

      1. 5.1.1 Nitrogen Blowdown Evaporators

      2. 5.1.2 Rotary Evaporators

      3. 5.1.3 Centrifugal Evaporators

      4. 5.1.4 Spiral Air Flow Evaporators

    2. 5.2 By End User

      1. 5.2.1 Research and Academic Institutes

      2. 5.2.2 Diagnostic Laboratories

      3. 5.2.3 Pharmaceutical and Biopharmaceutical Industry

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Biotage

      2. 6.1.2 Buchi Labortechnik AG

      3. 6.1.3 Heidolph Instruments GmbH & CO. KG

      4. 6.1.4 Labconco

      5. 6.1.5 Yamato Scientific Co.

      6. 6.1.6 Porvair PLC

      7. 6.1.7 KNF Neuberger Inc.

      8. 6.1.8 Steroglass Srl

    2. *List Not Exhaustive

**Subject to Availability
**Competitive Landscape Covers - Business Overview, Financials, Products and Strategies, and Recent Developments

Solvent Evaporation Industry Segmentation

As per the scope, solvent evaporation is an important technique used in preparing polymeric nanoparticles for pharmaceutical formulation. This technique involves the emulsification of an organic solvent, which comprise dissolved polymer and dissolved dispersed drug in the continuous phase. The Solvent Evaporation Market is segmented By Type (Nitrogen Blowdown Evaporators, Rotary Evaporators, Centrifugal Evaporators, and Spiral Air Flow Evaporators), End User (Research and Academic Institutes, Diagnostic Laboratories, and Pharmaceutical and Biopharmaceutical Industry), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.

By Type
Nitrogen Blowdown Evaporators
Rotary Evaporators
Centrifugal Evaporators
Spiral Air Flow Evaporators
By End User
Research and Academic Institutes
Diagnostic Laboratories
Pharmaceutical and Biopharmaceutical Industry
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Solvent Evaporation Market Research FAQs

The Global Solvent Evaporation Market is projected to register a CAGR of 6.5% during the forecast period (2023-2028).

Biotage, Buchi Labortechnik AG, Heidolph Instruments GmbH & CO. KG, Labconco and Yamato Scientific Co. are the major companies operating in the Global Solvent Evaporation Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2023-2028).

In 2023, the North America accounts for the largest market share in the Global Solvent Evaporation Market.

Solvent Evaporation Industry Report

Statistics for the 2023 Solvent Evaporation market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Solvent Evaporation analysis includes a market forecast outlook to 2028 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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