Postmenopausal Osteoporosis Market - Growth, Trends, Covid-19 Impact, And Forecasts (2022 - 2027)

The Postmenopausal Osteoporosis Market is segmented by Treatment (Vitamin D, Bisphosphonates, Hormone Therapy, Parathyroid Hormone Therapy, Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The report offers the value (USD million) for the above segments.

Market Snapshot

Postmenopausal Osteoporosis Market Size
Study Period: 2019-2027
Base Year: 2021
Fastest Growing Market: Asia-Pacific
Largest Market: North America
CAGR: 3.9 %

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Market Overview

The postmenopausal osteoporosis market is projected to register a CAGR of 3.9% during the forecast period.

The outbreak of Covid-19 has significantly impacted the healthcare industry, including relative negligence of chronic diseases such as osteoporosis. A survey conducted by the National Osteoporosis Foundation and International Osteoporosis Foundation concluded that the major impact includes delays in scanning for diagnosis, interruptions in the supply of drugs and raw material, an increase in telemedicine consultations, and a decrease in parenteral medicine delivery.

The aging population and lifestyle changes are the key factors responsible for the growth of the postmenopausal osteoporosis market. According to WHO statistics, the proportion of the world’s senior population (more than 60 years old) is expected to double from 12% to 22% from 2015 to 2050. This data showed a continuous increase in the geriatric population within the study period, which is the sufferer of postmenopausal osteoporosis (aged between 50 and 60 years). Hence, the market is projected to grow during the forecast period with an increase in demand for therapy.

Additionally, lifestyle changes such as lack of exercise, high consumption of alcohol or smoking, prolonged work duration, and unhealthy eating habits also impact the menopausal period and lead to osteoporosis in many women worldwide. Age, smoking, alcohol, and consumption of medications used to treat various diseases such as gonadotropins, excess consumption of thyroid hormone, and cytotoxic agents are some of the risk factors for causing low bone density and thereby developing osteoporosis after menopause in women. According to data published by the International Menopause Society (IMS), in 2021, more than 200 million women are estimated to suffer from osteoporosis, and 1 in 3 women aged more than 50 is expected to experience osteoporosis fracture.

Many women are diagnosed with postmenopausal osteoporosis after their first fracture (not before the fracture or as soon as the symptoms started) and hence restricted access to diagnosis and treatment of postmenopausal osteoporosis in under-developed countries hamper the market growth in coming years. Additionally, pricing pressure from generic drugs, as many lost their patent in the last few years, is expected to restrain the market growth.

Scope of the Report

When women go through a transitional menopausal period, more bone resorption happen than formation due to a drop in estrogen level, resulting in osteoporosis. Therapy or treatment for this condition is considered in the report's scope. The postmenopausal osteoporosis market is segmented by treatment (vitamin D, bisphosphonates, hormone replacement therapy, parathyroid hormone therapy, others), By distribution channel (hospital pharmacies, retail pharmacies, online pharmacies), and geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America).

By Treatment
Vitamin D
Hormone Replacement Therapy
Parathyroid Hormone Therapy
By Distribution Channel
Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
North America
United States
United Kingdom
Rest of Europe
South Korea
Rest of Asia-Pacific
Middle-East and Africa
South Africa
Rest of Middle-East and Africa
South America
Rest of South America

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Key Market Trends

The Bisphosphonates Segment Held the Largest Share of the Market in 2021 and is Projected to Observe the Same Dominance During the Forecast Period

The bisphosphonates class of drug accounted for the market's maximum share, which can be attributed to their ability to prevent the loss of bone density and thereby minimize the fracture risk by 50%. Additionally, bisphosphonates can be tolerated by most patients on a long-term basis. Hence, they are prescribed for most patients who have early-stage osteoporosis.

Alendronate, risedronate, ibandronate, and zoledronic acid are some of the most prescribed bisphosphonates to prevent and treat postmenopausal osteoporosis. A new regimen through the intravenous route is under investigation, and positive results from the trial can further accelerate the market of bisphosphonates during the forecast period. Bisphosphonates are generally prescribed for five years, and the bone-protective benefit of the drug continues even after the treatment discontinuation. Hence, adherence is also high for the bisphosphonate class of drug.

Global % of Population Affects (Over age of 50), by Sex

North America Dominates the Global Postmenopausal Osteoporosis Market and is Expected to do the Same in the Forecast Period

North America contributes the highest revenue in the market due to its developed healthcare infrastructure, presence of major industry players, high diagnosis and treatment rate, more patient compliance, and large patient base. The United States contributes the maximum share in North America. According to the data published by the Centers for Disease Control and Prevention (CDC) in 2021, about 18.8% of women aged 50 years or more had osteoporosis. The prevalence is expected to increase further due to sedentary lifestyles and unhealthy eating & drinking habits. According to the National Osteoporosis Foundation, it is projected that by 2030, about 71 million Americans will have osteoporosis and low bone mass condition.

High research and development activities due to investment by market players and research institutes are expected to further accelerate the market growth during the forecast period from 2022 to 2027. According to data published on, about 25 active Phase III and Phase IV clinical trials are going on in the United States. In April 2019, the United States Food and Drug Administration (US FDA) approved a new treatment, Evenity (romosozumab-aqqg), for the treatment of postmenopausal osteoporosis in women at high risk of bone fracture.

Postmenopausal Osteoporosis Market Analysis

Competitive Landscape

The postmenopausal osteoporosis market is fragmented and highly competitive due to several generics in the market. However, some of the key players operating in the market are Novartis International AG, Eli Lilly and CO., Pfizer Inc., Merck & Co., Inc., BiologicsMD, Allergan plc., and Cipla Inc.

Increasing awareness about postmenopausal osteoporosis, developing new drugs, and partnerships or collaborations to reach their drugs at maximum patients are some strategies market players are utilizing to gain market share in the industry.

Recent Developments

In January 2021, The Asia Pacific Consortium on Osteoporosis (APCO) launched pan-Asia Pacific clinical practice standards to screen, diagnose, and manage osteoporosis that will majorly target a broad range of high-risk groups. The program is expected to increase further awareness in the region, which is expected to boost the market in Asia-Pacific.

In June 2020, UCB S.A. and Amgen collaborated with the International Osteoporosis Foundation (IOF) to implement coordination programs for post-fracture care and reduce osteoporosis's public health burden across the globe. Both the companies are supporting the International Osteoporosis Foundation's "Capture the Fracture" program to decrease vertebral and hip fractures by 25% by 2025.

Table of Contents


    1. 1.1 Study Assumptions & Market Defination

    2. 1.2 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Increase in Geriatric Population

      2. 4.2.2 Investment by Market Players and Thereby Strong Pipeline

    3. 4.3 Market Restraints

      1. 4.3.1 Low Awarenss about Postmenopause Osteoporosis

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Treatment

      1. 5.1.1 Vitamin D

      2. 5.1.2 Bisphosphonates

      3. 5.1.3 Hormone Replacement Therapy

      4. 5.1.4 Parathyroid Hormone Therapy

      5. 5.1.5 Others

    2. 5.2 By Distribution Channel

      1. 5.2.1 Hospital Pharmacies

      2. 5.2.2 Retail Pharmacies

      3. 5.2.3 Online Pharmacies

    3. 5.3 Geography

      1. 5.3.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.3.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.3.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.3.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 Amgen Inc.

      2. 6.1.2 Eli Lilly and CO.

      3. 6.1.3 Pfizer Inc.

      4. 6.1.4 Proctor & Gamble Co.

      5. 6.1.5 Novartis International AG

      6. 6.1.6 Clonz Biotech

      7. 6.1.7 Ligand Pharmaceuticals Incorporated.

      8. 6.1.8 Merck & Co., Inc

      9. 6.1.9 BiologicsMD

      10. 6.1.10 Enteris BioPharma

      11. 6.1.11 Oncobiologics, Inc.

      12. 6.1.12 Allergan plc

    2. *List Not Exhaustive

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The Global Postmenopausal Osteoporosis Market market is studied from 2019 - 2027.

The Global Postmenopausal Osteoporosis Market is growing at a CAGR of 3.9% over the next 5 years.

Asia-Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2021.

Amgen Inc. , Eli Lilly and Co. , F. Hoffmann-La Roche Ltd , Merck & Co., Inc. , Allergan plc are the major companies operating in Global Postmenopausal Osteoporosis Market .

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