Chromatography Reagents Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)

The market is segmented by Type (Buffers, Ion Pair Reagents, Solvents, Other Types), Physical State of Mobile Phase (Gas Chromatography Reagents, Liquid Chromatography Reagents, and Super Critical Fluid Chromatography Reagents), Technology (Ion Exchange, Affinity Exchange, Size Exclusion, Hydrophobic Interaction, Mixed-Mode, and Other Technologies), Application (Pharmaceutical, Food and Beverages, Water and Environmental Analysis, and Other Applications), and Geography (Asia-Pacific, North America, Europe, South America, and Middle-East and Africa). The report offers market size and forecasts for Chromatography Reagents in revenue (USD million) for all the above segments.

Market Snapshot

chromatography reagents market share
Study Period: 2016 - 2026
Base Year: 2021
Fastest Growing Market: Europe
Largest Market: North America
CAGR: >6.5 %
chromatography reagents market major players

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Market Overview

The global chromatography reagents market stood at around USD 8,500 million in 2020 and is expected to register a CAGR of over 6.5% during the forecast period of 2021-2026.

The market was not affected by the COVID-19 pandemic in 2020, as it includes end-use applications such as pharmaceuticals and food and beverage. The demand for pharmaceuticals and food and beverage industry has increased during the COVID-19 pandemic, which has augmented the chromatography reagents market during 2020.

  • Over the short term, the major factors driving the growth of the market studied are the rising importance of chromatography across various industries and technological advancements in chromatography processes.
  • On the flip side, the high cost of chromatography systems and lack of skilled professionals​ serves as one of the major stumbling blocks in the growth of the studied market.
  • By application, pharmaceutical segment is expected to dominate the market and is likely to grow at fastest rate during the forecast period.
  • North America dominated the market across the world, where the growth is majorly driven by the growing adoption of chromatography technique in pharmaceutical, and food and beverage industries.

Scope of the Report

The chromatography reagents market report is segmented by type, physical state of mobile phase, technology, apllication and geography. By type market is segmented into buffers, ion pair reagents, solvents, other types. By physical state of mobile phase, the market is segmented by gas chromatography reagents, liquid chromatography reagents, and super critical fluid chromatography reagents. By technology market is segmented into ion exchange, affinity exchange, size exclusion, hydrophobic interaction, mixed-mode, and other tchnologies. By application market is segmented into pharmaceutical, food and beverages, water and environmental analysis, and other applications. The report also covers the market size of and forecasts for the chromatography reagents market in 15 countries across major regions. For each segment, the market sizing and forecasts have been done on the basis of revenue (USD million).

Ion Pair Reagents
Other Types
Physical State of Mobile Phase
Gas Chromatography Reagents
Liquid Chromatography Reagents
High Pressure Liquid Chromatography (HPLC) Reagents
Ultra High Pressure Liquid Chromatography (UHPLC) Reagents
Low Pressure Liquid Chromatography (LPLC) Reagents
Super Critical Fluid Chromatography (SFC) Reagents
Ion Exchange
Affinity Exchange
Size Exclusion
Hydrophobic Interaction
Other Technologies
Drug Discovery
Drug Production
Food and Beverages
Water and Environmental Analysis
Other Applications
South Korea
Rest of Asia-Pacific
North America
United States
United Kingdom
Rest of Europe
South America
Rest of South America
Middle-East and Africa
Saudi Arabia
South Africa
Rest of Middle-East and Africa

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Key Market Trends

Pharmaceutical Segment to Dominate the Market Demand

  • The pharmaceutical industry is one of the most regulated industries worldwide, since the drug products must be safe and effective. To ensure the least risk to patients, all pharmaceutical products must be of the highest quality. Various technological equipment and analytical procedures, including liquid chromatography, are used by researchers, manufacturers, and developers during the development process to ensure that the goods meet the requirements.
  • Chromatography is used in the pharmaceutical industry for a variety of purposes, including identifying and analyzing samples for the presence of chemicals or trace elements, preparing large quantities of extremely pure materials, separating chiral compounds, detecting mixture purity and unknown compounds present, and drug development.
  • The HPLC chromatography technique is the most important analytical techniques used in the pharmaceutical business for identifying and quantifying pharmaceuticals. During the research, development, and production of medicine, this is used either in the active pharmaceutical ingredient or in the formulations. The first step in drug development is to find a therapeutic molecule, which can be done utilizing the fast or ultra-quick HPLC chromatography technique for separation and high-throughput screening. This chromatography technique is commonly utilized in pharmacokinetics, bioassays, and metabolic research, owing to its great sensitivity and selectivity.
  • The basic principle and separation technique of GC are outlined in the GC section of the United States Pharmacopeia (USP) 27 Chapter. Residual solvent analysis, analysis of diverse functional groups, analysis of drugs of abuse, and determining the identity of natural products, including complicated mixtures of related compounds, are some of the applications of GC in pharmaceutical sectors.
  • The pharmaceutical segment across the globe has grown rapidly in the past five years. Moreover, the COVID-19 pandemic, which hampered many industries, had the opposite effect on the pharmaceuticals segment. IQVIA, an American MNC serving the combined industries of health information technology and clinical research, stated that the revenue of the global pharmaceutical segment was USD 1265.2 million in 2020. Several countries, like India, the United States, Germany, and others, increased their expenditure on pharmaceuticals/medicines over the recent years. This is boosting the global chromatography reagents market.
  • The use of pharmaceutical products remarkably increased over the years, for the treatment of multiple pathological conditions, such as genetic diseases and cancer. With the growing burden of diseases, the need for early diagnosis and treatments increases. The pharmaceutical and biotechnology companies increased their investment and research for such therapies, and as the chromatography reagents are highly required in such research process, the segment is expected to drive the growth of the market.
  • Therefore, with the growth of the pharmaceutical industry, the demand for chromatography reagents is likely to rise during the coming years.
chromatography reagents market trends

North American Region to Dominate the Market

  • North American region dominated the global market share. The increased adoption of chromatography technique, majorly in food and beverage and pharmaceutical industries, drives the demand for chromatography reagents in the region.
  • With the increase in the aging population in the region and the rising number of critical diseases, healthcare expenditure has increased significantly in the region. This has increased R&D investments into the pharmaceutical industry for drug discovery and production, which has further increased the demand for chromatography techniques and reagents in the region.
  • The United States stood as the largest consumer of chromatography reagents. The pharmaceutical sector, being the largest in the world, has been one of the major industries in the United States, as well as one of the most R&D intensive industries in the country. According to the IFPMA, the share of the pharmaceutical industry in the United States is expected to increase from an estimated 40.3% in 2015 to 41% in 2020.
  • The nominal spending on medicines in the country has been growing at a rapid rate since the past several years. In 2020, spending increased by 3.5% reaching a total of USD 539 billion.
  • The revenue from the food and beverages industry in the United States is estimated to reach USD 21,320 million in 2021. The revenue is expected to show an annual growth rate of over 4.7%, resulting in a projected market volume of over USD 25,000 million by 2025. This is expected to increase the demand for products such as food processing additives, flavoring agents, etc., thereby boosting the market of study in the country over the forecast period.
  • Moreover, the United States is one of the highest consumers of water in the world. Approximately 80% of the United States’ water and wastewater treatment industry is owned and managed publicly.
  • However, the rural part of the country has significantly lower access to water treatment infrastructure and facilitates in comparison to the urban areas. Since 2003, the United States Department of Agriculture (USDA) has funded around USD 10 billion for the construction and maintenance of 7,500 rural water and wastewater systems. It is planning to further increase its investment in the coming years. This growing investment in water treatment is likely to boost the demand for reagents used in the sector.
  • Hence, all such trends, along with discovery and production of drugs, and robust demand for food and beverages and pharmaceutical products in the region are expected to drive the demand for chromatography reagents, over the forecast period.
chromatography reagents market growth rate

Competitive Landscape

The chromatography reagents is a fragmented market, where few players account for a significant share of the market demand. Some of the major players in the market include Merck, Thermo Fisher Scientific Inc., Avantor, Agilent Technologies Inc., and Shimadzu Corporation, amongst others.

Table of Contents


    1. 1.1 Study Assumptions

    2. 1.2 Scope of the Study




    1. 4.1 Drivers

      1. 4.1.1 Rising Importance of Chromatography across Various Industries

      2. 4.1.2 Technological Advancements in Chromatography Processes

    2. 4.2 Restraints

      1. 4.2.1 High Costs of Chromatography Processes and Lack of Skilled Professionals​

    3. 4.3 Industry Value-Chain Analysis

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Bargaining Power of Suppliers

      2. 4.4.2 Bargaining Power of Consumers

      3. 4.4.3 Threat of New Entrants

      4. 4.4.4 Threat of Substitute Products and Services

      5. 4.4.5 Degree of Competition


    1. 5.1 Type

      1. 5.1.1 Buffers

      2. 5.1.2 Ion Pair Reagents

      3. 5.1.3 Solvents

      4. 5.1.4 Other Types

    2. 5.2 Physical State of Mobile Phase

      1. 5.2.1 Gas Chromatography Reagents

      2. 5.2.2 Liquid Chromatography Reagents

        1. High Pressure Liquid Chromatography (HPLC) Reagents

        2. Ultra High Pressure Liquid Chromatography (UHPLC) Reagents

        3. Low Pressure Liquid Chromatography (LPLC) Reagents

      3. 5.2.3 Super Critical Fluid Chromatography (SFC) Reagents

    3. 5.3 Technology

      1. 5.3.1 Ion Exchange

      2. 5.3.2 Affinity Exchange

      3. 5.3.3 Size Exclusion

      4. 5.3.4 Hydrophobic Interaction

      5. 5.3.5 Mixed-Mode

      6. 5.3.6 Other Technologies

    4. 5.4 Application

      1. 5.4.1 Pharmaceutical

        1. Biotechnology

        2. Drug Discovery

        3. Drug Production

      2. 5.4.2 Food and Beverages

      3. 5.4.3 Water and Environmental Analysis

      4. 5.4.4 Other Applications

    5. 5.5 Geography

      1. 5.5.1 Asia-Pacific

        1. China

        2. India

        3. Japan

        4. South Korea

        5. Rest of Asia-Pacific

      2. 5.5.2 North America

        1. United States

        2. Canada

        3. Mexico

      3. 5.5.3 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Rest of Europe

      4. 5.5.4 South America

        1. Brazil

        2. Argentina

        3. Rest of South America

      5. 5.5.5 Middle-East and Africa

        1. Saudi Arabia

        2. South Africa

        3. Rest of Middle-East and Africa


    1. 6.1 Mergers and Acquisitions, Joint Ventures, Collaborations, and Agreements

    2. 6.2 Market Share (%)**/Ranking Analysis

    3. 6.3 Strategies Adopted by Leading Players

    4. 6.4 Company Profiles

      1. 6.4.1 Agilent Technologies Inc.

      2. 6.4.2 Avantor

      3. 6.4.3 Bio-Rad Laboratories Inc.

      4. 6.4.4 Honeywell International Inc.​

      5. 6.4.5 ITW Reagents

      6. 6.4.6 Merck

      7. 6.4.7 Regis Technologies Inc.

      8. 6.4.8 Santa Cruz Biotechnology Inc.

      9. 6.4.9 Shanghai Aladdin Biochemical Technology Co. Ltd​

      10. 6.4.10 Shimadzu Corporation​

      11. 6.4.11 Thermo Fisher​

      12. 6.4.12 Tokyo Chemicals Industry​

      13. 6.4.13 Tosoh Corporation

      14. 6.4.14 Waters Corporation

    5. *List Not Exhaustive

    1. 7.1 Growing Awareness about the Benefits of Chromatography Reagents

**Subject to Availability

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Frequently Asked Questions

The Chromatography Reagents Market market is studied from 2016 - 2026.

The Chromatography Reagents Market is growing at a CAGR of >6.5% over the next 5 years.

The Chromatography Reagents Market is valued at 8500 Million USD in 2016.

Europe is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

Merck, Thermo Fisher Scientific Inc., Avantor, Agilent Technologies Inc., Shimadzu Corporation are the major companies operating in Chromatography Reagents Market.

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