T-Cell Lymphoma Market - Growth, Trends, Covid-19 Impact, and Forecasts (2022-2027)

The T-Cell Lymphoma Market is Segmented by Type of Lymphoma (Peripheral T-cell Lymphoma, Cutaneous T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angio-immuno-blastic T-cell Lymphoma, Other Types of Lymphoma), T-cell Lymphoblastic Lymphoma), Type of Therapy (Radiotherapy, Chemotherapy, Immunotherapy, Stem Cell Transplantation, Other Types of Therapies), and Geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The report offers the value (in USD million) for the above segments.

Market Snapshot

T-Cell Lymphoma Market Size
Study Period: 2019-2027
Base Year: 2021
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 8.25 %

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Market Overview

The T-cell lymphoma market was valued at USD 1,588.89 million in 2021, and it is expected to reach USD 2,701.45 million by 2027, registering a CAGR of 8.25% during the forecast period (2022-2027).

Due to the high transmission rate of COVID-19 and lack of treatment, many countries suffered, and they continue to bear a significant burden on their economies and healthcare systems. The COVID-19 outbreak may put patients with cutaneous lymphomas at additional risk of not receiving the necessary diagnostic procedures and treatment because they cannot access hospitals easily or due to healthcare resources limitations. Several guidelines for managing cutaneous lymphoma have been recently published to help dermatologists choose the right approach in the COVID-19 pandemic. However, these guidelines happen to be not applicable in countries that are still under a lockdown or do not have enough resources to implement the plan.

Moreover, the outbreak of COVID-19 impacted the cancer T-cell lymphoma market, as hospitals and healthcare services were significantly reduced due to social distancing measures enforced globally. The COVID-19 pandemic also affected the global economy and showed a huge impact on the general hospital care functioning for non-COVID-19 patients in hospitals across the world.

The growth of the T-cell lymphoma market is attributed to the rise in lymphoma cancer incidence due to radiations, an increase in the number of T-cell lymphoma-specific therapies, and the risk of lymphoma due to autoimmune disorders.

According to Leukemia & Lymphoma Society 2021, 186,400 people in the United States were diagnosed with leukemia and lymphoma in 2021. In addition, 825,651 people lived with lymphoma in the United States, 152,671 people lived with Hodgkin lymphoma, and 672,980 people lived with non-Hodgkin lymphoma. T-cell lymphoma is significantly contributing to non-Hodgkin lymphoma, which further boosts the overall market growth.

In addition, the growing uptake of premium-priced products such as Keytruda, Opdivo, and immune checkpoint inhibitors and the launch of several novel therapies with label extension of commercialized products are also boosting the overall market growth. However, the high cost associated with T-cell lymphoma treatment and the adverse side effects of therapies have been obstructing the overall market growth.

Scope of the Report

As per the scope of the report, lymphoma occurs when a lymphocyte, a type of white blood cell, is out of control inside the body, affecting the body's immune capacity to fight against infection. Lymphomas are grouped as Hodgkin (abnormal B-cells) and non-Hodgkin (developing from abnormal T-cells or B-cells) lymphomas. The T-cell lymphoma market is segmented by type of lymphoma (peripheral T-cell lymphoma, cutaneous T-cell Lymphoma, anaplastic large cell lymphoma, angio-immuno-blastic T-cell lymphoma, other types of lymphoma), T-cell lymphoblastic lymphoma), type of therapy (radiotherapy, chemotherapy, immunotherapy, stem cell transplantation, other types of therapies) and geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions globally. The report offers the value (in USD million) for the above segments.

By Type of Lymphoma
Peripheral T-cell Lymphoma
Cutaneous T-cell Lymphoma
Anaplastic Large Cell Lymphoma
Angio-immuno-blastic T-cell Lymphoma
Other Types of Lymphoma
T-cell Lymphoblastic Lymphoma
By Type of Therapy
Radiotherapy
Chemotherapy
Immunotherapy
Stem Cell Transplantation
Other Types of Therapies
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa
GCC
South Africa
Rest of Middle East & Africa
South America
Brazil
Argentina
Rest of South America

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Key Market Trends

Chemotherapy is Expected to Hold Significant Market Share over the Forecast Period

Chemotherapy is a type of drug treatment often used to treat lymphoma. It works by stopping and slowing down the growth of cancer cells. Surgery and radiation therapy works by removing, killing, or damaging the cancer cells in a particular area, but chemotherapy works throughout the whole body. This means that chemotherapy can destroy and damage cancer cells that have spread to other parts of the body away from the original tumor.

According to the European Society for Medical Oncology, the COVID-pandemic had generated a huge backlog in oncology care and research. In addition, cancer care was hit by the COVID-19 pandemic due to the halt in diagnostic procedures and surgical procedures. Moreover, as per many studies, cancer patients are more susceptible to coronavirus than individuals without cancer, as they are in an immunosuppressive state caused by the malignancy and anticancer treatment.

For instance, as per the American Society of Clinical Oncology, chemotherapy treatments and follow-ups were postponed during the COVID-19 pandemic. Even private clinics in major Indian cities reported a nearly 50% decrease in patients for cancer care. Overall cancer services declined by 50% in April and May 2020. As per a study titled ‘Impact of nationwide lockdown on cancer care during COVID-19 pandemic: A retrospective analysis from western India’ published in 2021, Chemotherapy was the most commonly received treatment (before lockdown 71.8% and during lockdown 45.9%).

Chemotherapy is used with surgery or radiation therapy, or both. In some cases, it is used in combination with other drugs, such as hormone therapy, targeted therapy, or immunotherapy. For example, chemo may be used to shrink a tumor before surgery or radiation therapy. Chemo used in this way is called neoadjuvant therapy or after surgery or radiation therapy to help kill any remaining cancer cells in the body. Chemo used in this way is called adjuvant therapy.

There are several types of chemotherapies given to T-cell lymphoma patients, including alkylating agents, plant alkaloids, antitumor antibiotics, antimetabolites, topoisomerase inhibitors, and miscellaneous antineoplastics.

Favorable reimbursement policies concerning these drugs, making them accessible and affordable, are expected to positively impact the market studied. For instance, Pralatrexate, a chemotherapy drug used to treat patients with relapsed/refractory peripheral T-cell lymphoma (PTCL), is listed under the PBS scheme by the Australian government.

Thus, with the rising awareness about the benefits of chemotherapy and favorable government policies, the market studied is expected to flourish during the forecast period.

USA

North America Dominates the Market, and it is Expected to do the Same over the Forecast Period

Some of the factors driving market growth in the North American region include the high prevalence of T-cell lymphoma, the presence of key market players, and increasing research and development activities.

The COVID-19 outbreak impacted the cancer T-cell lymphoma market, as hospitals and healthcare services were significantly reduced due to social distancing measures enforced in the North American region. Some biopharmaceutical companies, such as Merck & Co. Inc. and Eli Lilly and Company, announced clinical trial delays. For instance, the data from ClinicalTrials.gov showed that more than 200 interventional oncology studies were suspended in March and April 2020 as a result of the COVID-19 crisis. In addition, 60% of institutions in the United States are enrolling new patients at a lower rate.

According to the Globocan 2020 report, Canada had 8,506 cases of Non-Hodgkin lymphoma and 313 deaths caused due to it in 2020. This is expected to increase T-cell lymphoma incidence in the country. ​ The increase in cases of Non-Hodgkin lymphoma is expected to boost the demand for treatment options, which is going to positively aid market development, as T-cell lymphomas are a type of Non-Hodgkin lymphoma.

Some of the major companies that operate in the oncology segment in the North American region are adopting several strategies, such as collaboration and acquisition, to strengthen their positions in the T-cell lymphoma market. For instance, in August 2020, BostonGene Corporation announced the collaboration with The Weinstock Laboratory, which is at Dana-Farber Cancer Institute Inc. The collaboration is focused on defining predictors of response to PI3 kinase inhibition in relapsed/refractory T-cell lymphomas. In addition, other companies, such as Amgen and Merck, have been working on developing cancer therapies for T-cell lymphomas. Hence the aforementioned factors are expected to fuel market growth in this region.

T-Cell Lymphoma Market Growth

Competitive Landscape

The T-cell lymphoma market is highly competitive and consists of a few major players. Companies like Johnson & Johnson (Janssen Pharmaceuticals Inc.), Novartis AG, Bristol Myers Squibb Company, Merck & Co. Inc., and F. Hoffmann-La Roche Ltd hold a substantial share in the market.

Recent Developments

In September 2021, Soligenix Inc. announced that the US Food and Drug Administration's (FDA) Office of Orphan Products Development granted orphan drug designation to the active ingredient hypericin for the treatment of T-cell lymphoma, expanding the target population beyond the previously granted cutaneous T-cell lymphoma (CTCL).

In December 2020, the FDA cleared an investigational new drug application for LB1901, a chimeric antigen receptor T-cell therapy in development for the treatment of adults with relapsed or refractory T-cell lymphoma, according to the agent’s manufacturer.

In July 2020, miRagen Therapeutics Inc. announced that the Food and Drug Administration (FDA) had granted orphan drug designation to cobomarsen for the treatment of T-cell lymphoma. Cobomarsen is an inhibitor and is being developed by miRagen in two clinical programs to address different types of T-cell lymphomas, which include a Phase 2 trial for cutaneous T-cell lymphoma (CTCL) and a Phase 1 trial for adult T-cell lymphoma (ATLL).

Table of Contents

  1. 1. INTRODUCTION

    1. 1.1 Study Assumptions

    2. 1.2 Scope of the Study

  2. 2. RESEARCH METHODOLOGY

  3. 3. EXECUTIVE SUMMARY

  4. 4. MARKET DYNAMICS

    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Rise in Lymphoma Cancer Incidence

      2. 4.2.2 Advancements in T-cell Lymphoma-specific Therapies

      3. 4.2.3 Risk of Lymphoma due to Autoimmune Disorders

    3. 4.3 Market Restraints

      1. 4.3.1 High Cost of Treatment

      2. 4.3.2 Adverse Side Effects of Therapies

    4. 4.4 Porter's Five Forces Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry

  5. 5. MARKET SEGMENTATION (Market Size by Value – USD million)

    1. 5.1 By Type of Lymphoma

      1. 5.1.1 Peripheral T-cell Lymphoma

        1. 5.1.1.1 Cutaneous T-cell Lymphoma

        2. 5.1.1.2 Anaplastic Large Cell Lymphoma

        3. 5.1.1.3 Angio-immuno-blastic T-cell Lymphoma

        4. 5.1.1.4 Other Types of Lymphoma

      2. 5.1.2 T-cell Lymphoblastic Lymphoma

    2. 5.2 By Type of Therapy

      1. 5.2.1 Radiotherapy

      2. 5.2.2 Chemotherapy

      3. 5.2.3 Immunotherapy

      4. 5.2.4 Stem Cell Transplantation

      5. 5.2.5 Other Types of Therapies

    3. 5.3 Geography

      1. 5.3.1 North America

        1. 5.3.1.1 United States

        2. 5.3.1.2 Canada

        3. 5.3.1.3 Mexico

      2. 5.3.2 Europe

        1. 5.3.2.1 Germany

        2. 5.3.2.2 United Kingdom

        3. 5.3.2.3 France

        4. 5.3.2.4 Italy

        5. 5.3.2.5 Spain

        6. 5.3.2.6 Rest of Europe

      3. 5.3.3 Asia-Pacific

        1. 5.3.3.1 China

        2. 5.3.3.2 Japan

        3. 5.3.3.3 India

        4. 5.3.3.4 Australia

        5. 5.3.3.5 South Korea

        6. 5.3.3.6 Rest of Asia-Pacific

      4. 5.3.4 Middle East & Africa

        1. 5.3.4.1 GCC

        2. 5.3.4.2 South Africa

        3. 5.3.4.3 Rest of Middle East & Africa

      5. 5.3.5 South America

        1. 5.3.5.1 Brazil

        2. 5.3.5.2 Argentina

        3. 5.3.5.3 Rest of South America

  6. 6. COMPETITIVE LANDSCAPE

    1. 6.1 Company Profiles

      1. 6.1.1 Mundipharma International

      2. 6.1.2 Bristol-Myers Squibb Company

      3. 6.1.3 Genmab AS

      4. 6.1.4 Johnson & Johnson (Janssen Pharmaceuticals Inc.)

      5. 6.1.5 Merck & Co. Inc.

      6. 6.1.6 F. Hoffmann-La Roche Ltd

      7. 6.1.7 Novartis AG

      8. 6.1.8 Autolus Therapeutics PLC

      9. 6.1.9 Acrotech Biopharma

      10. 6.1.10 Macopharma

    2. *List Not Exhaustive
  7. 7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Competitive Landscape Covers - Business Overview, Financials, Products and Strategies, and Recent Developments

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Frequently Asked Questions

The Global T-Cell Lymphoma Market market is studied from 2019 - 2027.

The Global T-Cell Lymphoma Market is growing at a CAGR of 8.25% over the next 5 years.

The Global T-Cell Lymphoma Market is valued at 1588 Million USD in 2019.

The Global T-Cell Lymphoma Market is valued at 2701 Million USD in 2027.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2021.

Johnson & Johnson (Janssen Pharmaceuticals Inc.), Novartis AG, Bristol Myers Squibb Company, Merck & Co. Inc, F. Hoffmann-La Roche Ltd are the major companies operating in Global T-Cell Lymphoma Market.

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