High-Performance Liquid Chromatography (HPLC) Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 5 Billion |
| Market Size (2029) | USD 6.20 Billion |
| CAGR (2024 - 2029) | 4.45 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
High-Performance Liquid Chromatography (HPLC) Market Analysis
The High-Performance Liquid Chromatography Market size is estimated at USD 5 billion in 2024, and is expected to reach USD 6.20 billion by 2029, growing at a CAGR of 4.45% during the forecast period (2024-2029).
The COVID-19 pandemic significantly impacted the high-performance liquid chromatography (HPLC) market. For instance, a study published in the Journal of Pharmaceutical and Biomedical Analysis in May 2022 studied the permeability quantitation of Molnupiravir in nanoformulations. The study established that the reversed-phase HPLC method is more applicable for the routine analysis of Molnupiravir compared to the Liquid Chromatography - Mass Spectrometry / Mass Spectrometry methods. Furthermore, according to an article published by WHO in November 2021, the established method HPLC was employed to quantify remdesivir in marketed pharmaceutical formulations. The rise in the applications of HPLC systems in the COVID-19 study propelled the growth of the studied market. However, as the COVID-19 cases started to decline, the market began to show normal pre-pandemic level growth and is likely to continue its significant growth rate during the forecast period.
Factors such as advancements in HPLC technologies and the surge in usage of HPLC in pharmaceutical and bio-pharmaceutical companies are expected to drive the market's growth over the forecast period. For instance, according to an article published in the Journal of Current Opinion in Chemical Engineering in June 2021, HPLC is highly versatile, used for fast analysis and high-yield separation at both preparative and process scales, and is the most common separation method in the production of pharmaceutical and biopharmaceutical products. The article indicated that the combination of computational and experimental work could help the adoption of more complex models, reduce the simulation time, and facilitate faster screening of multidimensional operation spaces for parameter estimation and optimization. The advances made in the HPLC sector will likely add to the market growth in the forecast period.
Several key market players have also been interested in developing and manufacturing innovative HPLC-based systems for various laboratory functions, including diagnostics. For instance, in June 2021, Trivitron Healthcare launched HPLC-based diagnostic solutions, the HbA1c analyzers for monitoring diabetes, thalassemia, and hemoglobin variants. The fully automated NANO H5 analyzer can process five samples at a time. The NANO H110 is a compact, automated HPLC analyzer with a dual test mode for HbA1c test and Hb Variant detection, with a high sample loading capacity of 110 samples at a time. Such innovations are expected to propel market growth in the study period.
However, the lack of skilled personnel and the high cost of the HPLC systems will likely hinder the market growth in the forecast period.
High-Performance Liquid Chromatography (HPLC) Market Trends
Consumables Segment is Expected to Hold a Significant Share in the High-Performance Liquid Chromatography (HPLC) Market
HPLC consumables are the columns, reagents, tubes, and other products that are used for high-performance liquid chromatography techniques. Due to the advancements in column technologies and pumps, the segment is anticipated to grow at significant rates. The pharma and biopharmaceutical companies manufacturing HPLC systems are anticipated to grow at a significant rate owing to the increasing need for the development of new therapeutics to address the growing prevalence of chronic diseases around the world and an increase in government expenditure in research and development of biotechnology. For instance, according to a study published by Analytical Liquid Chromatography in May 2022, the chromatographic column is an essential part of HPLC separation. Significant progress has been made in developing columns with better performance to provide better separation, a shorter separation time, resilience to a wider pH range of the mobile phase, longer lifetime, use of lower volumes of the mobile phase, etc. Such advancements in these columns are expected to drive segmental growth.
Recent advances made by the market players in the research and development of novel HPLC techniques are also adding to the market's growth. For instance, in February 2022, Thermo Fisher Scientific launched a new portfolio of high-performance chromatography and mass spectrometry consumables called SureStart, which includes a new collection of caps, vials, inserts, kits, well plates, and mats. The Thermo Scientific SureStart portfolio is compatible with all add-ons and chromatography autosamplers, allowing analysts to use the new portfolio in all systems. Such research and developments in High-Performance Liquid Chromatography (HPLC) techniques are expected to propel the market growth over the forecast period.
Thus, owing to the abovementioned factors, the consumables segment is expected to project significant growth over the forecast period.
North America is Expected to Hold a Significant Share in the Market Over the Forecast Period
The rise in the adoption of highly advanced techniques and systems in manufacturing High-Performance Liquid Chromatography (HPLC) and the technological advancements made in chromatographic studies is expected to boost the market's growth in the North American region. The high awareness among the research personnel on the availability of innovative chromatography studies in the market contributes to the increased market growth in the area. Various governmental research organizations in the United States use the HPLC technique to analyze specific components in a drug mixture or similar elements. An article published by the United States Environmental Protection Agency, updated in May 2021, on the High-PerformanceEnvironmental Sampling and Analytical Methods (ESAM) Program focused on Determining Carbonyl Compounds by using High-Performance Liquid Chromatography (HPLC). Such application of HPLC techniques as standard protocols for sample analysis adds to the market's growth in the North American region.
The launch of innovative High-Performance Liquid Chromatography (HPLC) systems by the key market players also adds to the market's growth. For instance, in February 2021, Waters launched ACQUITY PREMIER Liquid Chromatography Solution, which combines the ACQUITY PREMIER System with ACQUITY PREMIER Columns with MaxPeak HPS technology. It is designed to alleviate the problem of analyte/metal surface interactions when analyzing organic acids, organophosphates, oligonucleotides, phosphopeptides, acidic glycans, and phospholipids by reversed-phase and hydrophilic interaction chromatography. Such activities are expected to propel market growth over the forecast period.
Thus, the increasing necessity for High-Performance Liquid Chromatography (HPLC) is known to propel the market growth in this region.
High-Performance Liquid Chromatography (HPLC) Industry Overview
The High-Performance Liquid Chromatography (HPLC) market is fragmented in nature due to the presence of several companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international as well as local companies that hold significant market shares and are well known, including Merck KGaA, Bio-Rad Laboratories Inc., Mitsubishi Chemical Corporation, Tosoh Corporation, and General Electric (Cytiva Life Sciences).
High-Performance Liquid Chromatography (HPLC) Market Leaders
Merck KGaA
Bio-Rad Laboratories, Inc.
Mitsubishi Chemical Corporation
Tosoh Corporation
General Electric (Cytiva Life Sciences)
*Disclaimer: Major Players sorted in no particular order
High-Performance Liquid Chromatography (HPLC) Market News
- Feb 2022: Shimadzu Corporation launched the Nexera XS inert high-performance liquid chromatograph globally. The Nexera XS inert incorporates rust-resistant materials and nonmetallic materials that limit the adsorption of molecules to provide stable measurements of biopharmaceuticals and medium molecule pharmaceuticals.
- Jan 2022: Bruker Corporation acquired Prolab Instruments GmbH, a Swiss technology company specializing in low-flow, high-precision liquid chromatography technology and systems.
High-Performance Liquid Chromatography (HPLC) Market Report - Table of Contents
1. INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Advancements in HPLC Technologies
4.2.2 The Surge in Usage of HPLC in Pharmaceutical and Biopharmaceutical Companies
4.3 Market Restraints
4.3.1 High Cost of the HPLC Systems
4.3.2 Lack of Skilled Professionals
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value - in USD Millions)
5.1 By Product Type
5.1.1 Instruments
5.1.1.1 Systems
5.1.1.2 Detectors
5.1.1.3 Pumps
5.1.1.4 Other Instruments
5.1.2 Consumables
5.1.3 Accessories
5.2 By Application
5.2.1 Protein Expression
5.2.2 Cloning
5.2.3 Other Applications
5.3 By End User
5.3.1 Pharma Bio-pharmaceutical Companies
5.3.2 Contract Research Organizations
5.3.3 Academic Institutions
5.4 Geography
5.4.1 North America
5.4.1.1 United States
5.4.1.2 Canada
5.4.1.3 Mexico
5.4.2 Europe
5.4.2.1 Germany
5.4.2.2 United Kingdom
5.4.2.3 France
5.4.2.4 Italy
5.4.2.5 Spain
5.4.2.6 Rest of Europe
5.4.3 Asia-Pacific
5.4.3.1 China
5.4.3.2 Japan
5.4.3.3 India
5.4.3.4 Australia
5.4.3.5 South Korea
5.4.3.6 Rest of Asia-Pacific
5.4.4 Middle-East and Africa
5.4.4.1 GCC
5.4.4.2 South Africa
5.4.4.3 Rest of Middle-East and Africa
5.4.5 South America
5.4.5.1 Brazil
5.4.5.2 Argentina
5.4.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Merck KGaA
6.1.2 Bio-Rad Laboratories Inc.
6.1.3 Mitsubishi Chemical Corporation
6.1.4 Tosoh Corporation
6.1.5 General Electric (Cytiva Life Sciences)
6.1.6 Agilent Technologies Inc.
6.1.7 PerkinElmer Inc.
6.1.8 Gilson Inc.
6.1.9 Thermo Fisher Scientific
6.1.10 Shimadzu Corporation
6.1.11 Waters
6.1.12 Hitachi High-Tech Corporation
6.1.13 Hamilton Company
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
High-Performance Liquid Chromatography (HPLC) Industry Segmentation
As per the scope of the report, High-performance liquid chromatography (HPLC) is used to separate, identify, and quantify the components in a given mixture. HPLC is one of the types of column chromatography in which the components are separated using solubility.
The High-Performance Liquid Chromatography (HPLC) Market is Segmented by Product Type (Instruments (Systems, Detectors, Pumps, and Other Instruments), Consumables, and Accessories), Application (Protein Expression, Cloning, and Other Applications), End User (Pharma Bio-pharmaceutical Companies, Contract Research Organizations, and Academic Institutions), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions globally. The report offers the value (in USD) for the above segments.
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High-Performance Liquid Chromatography (HPLC) Market Research FAQs
How big is the High-Performance Liquid Chromatography Market?
The High-Performance Liquid Chromatography Market size is expected to reach USD 5 billion in 2024 and grow at a CAGR of 4.45% to reach USD 6.20 billion by 2029.
What is the current High-Performance Liquid Chromatography Market size?
In 2024, the High-Performance Liquid Chromatography Market size is expected to reach USD 5 billion.
Who are the key players in High-Performance Liquid Chromatography Market?
Merck KGaA, Bio-Rad Laboratories, Inc., Mitsubishi Chemical Corporation, Tosoh Corporation and General Electric (Cytiva Life Sciences) are the major companies operating in the High-Performance Liquid Chromatography Market.
Which is the fastest growing region in High-Performance Liquid Chromatography Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in High-Performance Liquid Chromatography Market?
In 2024, the North America accounts for the largest market share in High-Performance Liquid Chromatography Market.
What years does this High-Performance Liquid Chromatography Market cover, and what was the market size in 2023?
In 2023, the High-Performance Liquid Chromatography Market size was estimated at USD 4.78 billion. The report covers the High-Performance Liquid Chromatography Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the High-Performance Liquid Chromatography Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
High-performance Liquid Chromatography Industry Report
Statistics for the 2024 High-performance Liquid Chromatography market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. High-performance Liquid Chromatography analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
