Mass Spectrometry Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Mass Spectrometry Market Report is Segmented by Technology (Hybrid Mass Spectrometry, Single Mass Spectrometry, MALDI-TOF Mass Spectrometry, and More), Component (Instruments, Ionization Sources, and More), Application (Pharmaceutical & Biotechnology, and More), and Geography (North America, Europe, Asia-Pacific, Middle East & Africa, South America). The Market Forecasts are Provided in Terms of Value (USD).

Mass Spectrometry Market Size and Share

Mass Spectrometry Market (2025 - 2030)
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Compare market size and growth of Mass Spectrometry Market with other markets in Healthcare Industry

Mass Spectrometry Market Analysis by Mordor Intelligence

The Mass Spectrometry Market size is estimated at USD 7.16 billion in 2025, and is expected to reach USD 10.13 billion by 2030, at a CAGR of 7.17% during the forecast period (2025-2030).

Momentum stems from rising biologics characterization, tighter food-safety oversight, miniaturized point-of-care systems, artificial-intelligence (AI) data analytics, and multi-omics funding. North America’s mature research ecosystem and stringent regulatory framework keep the region at the forefront, yet Asia-Pacific’s double-digit trajectory signals a geographical power shift. Competitive differentiation is gravitating toward software-hardware integration, as user demand for real-time, high-throughput insights eclipses pure instrument specifications. Meanwhile, capital constraints in developing-country academic facilities and persistent talent gaps temper adoption, underscoring the need for creative financing and training programs.

Key Report Takeaways

  • By technology, hybrid mass spectrometry commanded 46.82% of the mass spectrometry market share in 2024, while matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) is projected to accelerate at an 11.45% CAGR to 2030.
  • By component, instruments held 71.27% of the mass spectrometry market in 2024; software and informatics represent the fastest growth path, with a 12.16% CAGR through 2030.
  • By application, the pharmaceutical and biotechnology segment led with 34.71% revenue share in 2024; clinical diagnostics and proteomics are advancing at a 12.83% CAGR to 2030.
  • By geography, North America retained 35.19% of the mass spectrometry market in 2024, whereas Asia-Pacific is on track to expand at a 10.38% CAGR between 2025 and 2030.

Segment Analysis

By Technology: MALDI-TOF Reshapes Clinical Workflows

Hybrid architectures continued to dominate 46.82% of the mass spectrometry market share in 2024, yet MALDI-TOF platforms exhibit the steepest trajectory, posting an 11.45% CAGR outlook. MALDI-TOF’s rapid microbial identification slashed diagnostic turnaround to minutes, lowering hospitalization costs. Beyond microorganisms, MALDI HiPLEX-IHC now delivers multiplexed intact-protein imaging at 5 µm spatial resolution, enabling spatial proteomics in oncology tissue sections.

Second-generation MALDI units also tackle rapid microbiota classification with near-90% accuracy, broadening usage in gut-microbiome studies. Integration with machine-learning algorithms automates spectral-fingerprint libraries, a key differentiator as hospital laboratories scale throughput demands.

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Note: Segment shares of all individual segments available upon report purchase

By Component: Software Unlocks Analytical Value

Instruments constituted 71.27% of the mass spectrometry market for components in 2024, yet software and informatics projected to register a 12.16% CAGR between 2025 and 2030. Empower, adopted in 80% of 2023 novel-drug filings, illustrates the regulatory confidence vendors capture through validated data-handling platforms.

MZmine 3 harmonizes inputs from ion-mobility, time-of-flight, and orbitrap instruments into a single workspace, breaking down vendor silos and elevating user productivity. Looking forward, AI-driven annotation engines anticipate expanding the accessible chemical space, compressing data-review timelines, and freeing capacity for higher-value interpretation.

By Application: Diagnostics Surges Ahead

Pharmaceutical and biotechnology laboratories retained 34.71% revenue in 2024, but clinical diagnostics and proteomics are advancing at a brisk 12.83% CAGR. In onychomycosis detection, MALDI-TOF reached 95.4% sensitivity and 97.5% specificity, highlighting disruptive accuracy over culture-based assays.

Minimal residual disease tracking in multiple myeloma reveals another leap: the EXENT automated MALDI-TOF system identified low-level M-proteins even when standard serum electrophoresis missed them. Such use cases underline the clinical imperative for precise, high-throughput, and cost-effective mass spectrometry diagnostics.

Mass Spectrometry Market: Market Share by Application
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Note: Segment shares of all individual segments available upon report purchase

Geography Analysis

North America contributed 35.19% to the mass spectrometry market in 2024, owing to strong National Institutes of Health funding, a vibrant biotech pipeline, and stringent environmental regulations. The United States Environmental Protection Agency’s PFAS mandates require lower detection limits, driving instrument refresh cycles, and specialized consumables. Canada is following up with updated drinking-water quality guidelines, spurring provincial tenders.

Asia-Pacific is forecast to expand at a 10.38% CAGR to 2030 and is central to future volume growth. China’s manufacturers secured venture funding to commercialize miniaturized direct-ionization devices, aiming to address domestic demand and export opportunities. Parallel expansion of contract development and manufacturing organizations (CDMOs) in India and South Korea creates recurring demand for compliance-ready platforms.

Europe remains a stable, high-value market, anchored by stringent EFSA and EMA regulations. The ECHA’s continuously evolving chemical-safety framework necessitates frequent method-validation updates, sustaining service revenue streams. Middle East & Africa and South America, though smaller in total addressable revenue, exhibit momentum through GCC public-health investments and Brazil’s agrochemical-residue monitoring programs, respectively.

Mass Spectrometry Market CAGR (%), Growth Rate by Region
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Competitive Landscape

Competition centers on five global leaders: Thermo Fisher Scientific, Agilent Technologies, Waters Corporation, Bruker Corporation, and Danaher (SCIEX). Together, they capture the largest share, with Thermo Fisher solidifying its edge via the 2024 Stellar platform that unites fast throughput with translational-omics versatility.

Agilent’s ExD Cell retrofit strategy lets users bolster legacy LC/Q-TOFs for complex biotherapeutic characterization, illustrating the value of modularity. Waters focuses on workflow-centric software; Empower’s regulatory track record increases customer stickiness. Bruker’s majority purchase of RECIPE brings ready-to-run diagnostic kits that simplify triple-quad deployment in routine clinical labs. Danaher’s SCIEX unit emphasizes differentiated analytical-service contracts that guarantee uptime.

Emerging challengers attack niches, portable formats, AI-augmented data mining, and modular detector add-ons rather than trying to out-spec incumbents on resolution. Patent filings such as Thermo Fisher Bremen’s time-of-flight peak-deconvolution algorithm confirm that proprietary computation is joining ion source design as a primary competitive frontier.

Mass Spectrometry Industry Leaders

  1. Thermo Fisher Scientific Inc.

  2. Agilent Technologies Inc.

  3. Danaher Corporation (SCIEX)

  4. Waters Corporation

  5. Bruker Corporation

  6. *Disclaimer: Major Players sorted in no particular order
Mass Spectrometry Market
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Recent Industry Developments

  • April 2025: Bruker has announced the majority acquisition of RECIPE, a leading provider of mass spectrometry-based diagnostic assay kits. This strategic move strengthens Bruker's position in the field of therapeutic drug monitoring (TDM). The two companies are collaborating to pioneer the high-throughput, "chrom-free" ClinDART triple-quad mass spectrometry (MS) platform, designed to deliver robust and cost-effective TDM assays. This advancement aims to improve clinical diagnostics by offering more efficient and accessible monitoring solutions for therapeutic drug levels, benefiting both healthcare providers and patients.
  • June 2024: Thermo Fisher Scientific launched the Stellar mass spectrometer at the ASMS conference, emphasizing fast throughput, high sensitivity, and ease of use for translational omics research. It integrates with the Ardia platform and Vanquish Neo UHPLC system.
  • June 2024: Bruker Corporation introduced the Neoflex Imaging Profiler, a MALDI-TOF/TOF mass spectrometry system for tissue imaging. It features a 10-kHz smart beam 3D laser and enhanced imaging detectors to transition from discovery imaging to clinical tissue research.
  • June 2024: Agilent Technologies announced the launch of the 7010D Triple Quadrupole GC/MS System and the ExD Cell for the 6545XT AdvanceBio LC/Q-TOF at the ASMS 2024 conference. These systems target food, environmental markets, and complex biotherapeutics analysis.

Table of Contents for Mass Spectrometry Industry Report

1. Introduction

  • 1.1 Study Assumptions & Market Definition
  • 1.2 Scope of the Study

2. Research Methodology

3. Executive Summary

4. Market Landscape

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Evolving Biologics & Large-Molecule Characterization Needs
    • 4.2.2 Stringent Food-Safety Regulations Accelerating Adoption
    • 4.2.3 Miniaturization & High-Throughput Screening Demand in Clinical Diagnostics
    • 4.2.4 Rising Multi-omics Research Funding
    • 4.2.5 Increasing R&D Expenditure by Private and Government Research Organizations
    • 4.2.6 Emergence of Ambient and Portable Mass Spectrometry Technologies
  • 4.3 Market Restraints
    • 4.3.1 Capital-Expenditure Constraints in Academic Core Facilities Across Developing Countries
    • 4.3.2 Shortage of Experienced Mass-Spectrometrists in Emerging Markets
    • 4.3.3 Data-Management & Standardization Challenges in Large-Scale Omics Projects
    • 4.3.4 Lengthy Instrument Validation and Regulatory Approval Cycles
  • 4.4 Technological Outlook
  • 4.5 Porter’s Five Forces Analysis
    • 4.5.1 Threat of New Entrants
    • 4.5.2 Bargaining Power of Buyers
    • 4.5.3 Bargaining Power of Suppliers
    • 4.5.4 Threat of Substitutes
    • 4.5.5 Intensity of Competitive Rivalry

5. Market Size & Growth Forecasts (Value in USD)

  • 5.1 By Technology
    • 5.1.1 Hybrid Mass Spectrometry
    • 5.1.1.1 Triple Quadrupole (LC-MS/MS)
    • 5.1.1.2 Quadrupole Time-of-Flight (Q-TOF)
    • 5.1.1.3 Fourier-Transform (FT-MS)
    • 5.1.2 Single Mass Spectrometry
    • 5.1.2.1 Quadrupole
    • 5.1.2.2 Time-of-Flight (TOF)
    • 5.1.2.3 Ion Trap
    • 5.1.3 MALDI-TOF Mass Spectrometry
    • 5.1.4 Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
    • 5.1.5 Others
  • 5.2 By Component
    • 5.2.1 Instruments
    • 5.2.2 Ionization Sources
    • 5.2.3 Detectors & Analyzers
    • 5.2.4 Software & Informatics
    • 5.2.5 Services
  • 5.3 By Application
    • 5.3.1 Pharmaceutical & Biotechnology
    • 5.3.2 Clinical Diagnostics & Proteomics
    • 5.3.3 Food & Beverage Testing
    • 5.3.4 Environmental Testing
    • 5.3.5 Chemical & Petrochemical
    • 5.3.6 Forensic & Toxicology
    • 5.3.7 Academia & Research Institutes
    • 5.3.8 Others
  • 5.4 By Geography
    • 5.4.1 North America
    • 5.4.1.1 United States
    • 5.4.1.2 Canada
    • 5.4.1.3 Mexico
    • 5.4.2 Europe
    • 5.4.2.1 Germany
    • 5.4.2.2 United Kingdom
    • 5.4.2.3 France
    • 5.4.2.4 Italy
    • 5.4.2.5 Spain
    • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
    • 5.4.3.1 China
    • 5.4.3.2 Japan
    • 5.4.3.3 India
    • 5.4.3.4 Australia
    • 5.4.3.5 South Korea
    • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East & Africa
    • 5.4.4.1 GCC
    • 5.4.4.2 South Africa
    • 5.4.4.3 Rest of Middle East & Africa
    • 5.4.5 South America
    • 5.4.5.1 Brazil
    • 5.4.5.2 Argentina
    • 5.4.5.3 Rest of South America

6. Competitive Landscape

  • 6.1 Market Concentration
  • 6.2 Market Share Analysis
  • 6.3 Company Profiles (includes Global level Overview, Market level overview, Core Segments, Financials as available, Strategic Information, Market Rank/Share for key companies, Products & Services, and Recent Developments)
    • 6.3.1 Agilent Technologies Inc.
    • 6.3.2 Thermo Fisher Scientific Inc.
    • 6.3.3 Waters Corporation
    • 6.3.4 Bruker Corporation
    • 6.3.5 Shimadzu Corporation
    • 6.3.6 Danaher Corporation (SCIEX)
    • 6.3.7 PerkinElmer Inc.
    • 6.3.8 LECO Corporation
    • 6.3.9 JEOL Ltd.
    • 6.3.10 Hitachi High-Tech Corporation
    • 6.3.11 MKS Instruments (Extrel)
    • 6.3.12 Bio-Rad Laboratories Inc.
    • 6.3.13 Advion Inc.
    • 6.3.14 Kore Technology Ltd.
    • 6.3.15 Analytik Jena GmbH
    • 6.3.16 Rigaku Corporation
    • 6.3.17 Teledyne FLIR (FLIR Systems)
    • 6.3.18 TOFWERK AG
    • 6.3.19 Hiden Analytical Ltd.
    • 6.3.20 OI Analytical

7. Market Opportunities & Future Outlook

  • 7.1 White-Space & Unmet-Need Assessment
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Global Mass Spectrometry Market Report Scope

As per the scope of this report, mass spectrometry (MS) is an analytical chemistry technique used to identify the amount and type of chemical species present in a sample, by measuring the mass-to-charge ratio and abundance of gas-phase ions. 

The Mass Spectrometry Market is Segmented by Technology (Hybrid Mass Spectrometry (Triple Quadrupole (Tandem), Quadrupole TOF (Q-TOF), and FTMS (Fourier Transform Mass Spectrometry), Single Mass Spectrometry (ION Trap, Quadrupole, and Time-of-Flight (TOF)), and Inductively Coupled Plasma Mass Spectrometry), Application (Chemical Industry, Academic Research, Pharmaceutical and Biotechnology Companies, and Others), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

By Technology Hybrid Mass Spectrometry Triple Quadrupole (LC-MS/MS)
Quadrupole Time-of-Flight (Q-TOF)
Fourier-Transform (FT-MS)
Single Mass Spectrometry Quadrupole
Time-of-Flight (TOF)
Ion Trap
MALDI-TOF Mass Spectrometry
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Others
By Component Instruments
Ionization Sources
Detectors & Analyzers
Software & Informatics
Services
By Application Pharmaceutical & Biotechnology
Clinical Diagnostics & Proteomics
Food & Beverage Testing
Environmental Testing
Chemical & Petrochemical
Forensic & Toxicology
Academia & Research Institutes
Others
By Geography North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa GCC
South Africa
Rest of Middle East & Africa
South America Brazil
Argentina
Rest of South America
By Technology
Hybrid Mass Spectrometry Triple Quadrupole (LC-MS/MS)
Quadrupole Time-of-Flight (Q-TOF)
Fourier-Transform (FT-MS)
Single Mass Spectrometry Quadrupole
Time-of-Flight (TOF)
Ion Trap
MALDI-TOF Mass Spectrometry
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Others
By Component
Instruments
Ionization Sources
Detectors & Analyzers
Software & Informatics
Services
By Application
Pharmaceutical & Biotechnology
Clinical Diagnostics & Proteomics
Food & Beverage Testing
Environmental Testing
Chemical & Petrochemical
Forensic & Toxicology
Academia & Research Institutes
Others
By Geography
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East & Africa GCC
South Africa
Rest of Middle East & Africa
South America Brazil
Argentina
Rest of South America
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Key Questions Answered in the Report

What is the current value of the mass spectrometry market?

The mass spectrometry market size stands at USD 7.16 billion in 2025 and is projected to reach USD 10.13 billion by 2030.

Which technology segment is growing the fastest?

MALDI-TOF leads with an expected 11.45% CAGR to 2030 thanks to rapid microbial-identification and tissue-imaging applications.

Why is Asia-Pacific considered the most attractive growth region?

Expanding pharmaceutical manufacturing bases, stricter environmental policies, and rising clinical adoption drive a 10.38% CAGR forecast for Asia-Pacific.

How are software tools influencing buyer decisions?

Validated informatics suites like Empower and MZmine 3 enable regulatory-grade data handling and multimodal analysis, making software a key purchase determinant.

What factors inhibit wider mass spectrometry uptake in developing nations?

High capital costs, limited grant funding, and shortages of trained mass-spectrometrists constrain instrument deployment in emerging markets.

Which clinical application areas show the greatest promise?

Point-of-care pathogen identification and minimal residual disease monitoring in oncology are among the fastest-expanding diagnostic opportunities for mass spectrometry.

Page last updated on: March 18, 2025