Ubiquitin Proteasome Market - Growth, Trends, COVID-19 Impact, and Forecasts (2021 - 2026)

The Ubiquitin Proteasome market is segmented by Application (Scientific Research and Treatment), and Geography

Market Snapshot

Study Period: 2018 - 2026
Base Year: 2020
Fastest Growing Market: Asia Pacific
Largest Market: North America
CAGR: 3.9 %

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Market Overview

The Ubiquitin Proteasome market studied is anticipated to grow with a CAGR of nearly 3.9%, during the forecast period.

Certain factors that are driving the market growth include rising prevalence of cancer and neurodegenerative diseases and an increase in research and development activities. According to the WHO, Cancer is the second leading cause of death globally and was responsible for an estimated 9.6 million deaths in 2018. Globally, about 1 in 6 deaths is due to cancer. Approximately 70% of deaths from cancer occur in low- and middle-income countries.

As data is being generated aggressively in the healthcare sector, a few developing countries have surpassed the lack of data, and it is likely to become so in the remaining countries as well. This augmentation of data is expected to provide the basis for any national policy on cancer. In turn, this factor may possibly lead to an increase in the percentage of people opting for cancer treatment.

Additionally, with increasing global population and average lifespan, the prevalence of neurological disorders is on the rise, worldwide. According to a study by the Parkinson’s Disease Foundation, the number of new cases of the disease has increased over the last 30 years. Globally, over 10 million people are living with Parkinson's disease, according to the statistics of 2016. The Alzheimer's Association stated that around 5.4 million people in the United States were living with Alzheimer’s disease, in 2016.

Scope of the Report

The Ubiquitin Proteasome Pathway (UPP) is the principal mechanism for protein catabolism in the mammalian cytosol and nucleus. The highly regulated UPP affects a wide variety of cellular processes and substrates and defects in the system can result in the pathogenesis of several important human diseases. The drugs that work based on and target this pathway are used to treat such diseases. It also has extensive application in research field, since ubiquitin, Uch-L1, and the proteasome can be manipulated pharmacologically providing convenient methods for research applications.

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Key Market Trends

Cancer Holds Significant Share in the Treatment Market

  • Globally, cancer is one of the leading causes of death. The disease witnessed significant growth in the last few decades, and it is expected to grow rapidly over the forecast period. The World Health Organization (WHO) estimates the rate of cancer number to increase to 70% over the next two decades.
  • Additionally, the increased burden of several lifestyle disorders is also expected to drive the market. As per the American Cancer Society, in 2018, the United States witnessed around 164,690 new cases of prostate cancer, causing over 26,430 deaths. About 60% of the total prostate cancer cases diagnosed are among men aged 65 years or older. In order to tackle such challenges, extensive research in the field of therapeutics has been undertaken. Overall, with such a high prevalence rate of cancer across the world, the demand for Ubiquitin Proteasome is sure to rise, in turn, leading to the growth of this segment in the years to come.
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North America Dominates the Global Ubiquitin Proteasome Market

The United States has witnessed a considerable rise in the number of cancer patients. According to the American Cancer Society, in 202, there will be approximately 89,500 cancer cases diagnosed and about 9,250 cancer deaths in adolescents and young adults (AYAs) ages 15 to 39 years in the US. Prostate and breast cancers are the most prevalent forms of cancer in the region.

Similarly, according to the National Institute of Health, approximately 1.2 million people in the United States are predicted to have Parkinson’s disease by 2030. It is the second-most common neurodegenerative disorder in the United States. In addition, there are thousands of patients who go undetected. As the aging population levels continue to grow, the number of people suffering from Parkinson's disease (PD) will continue to grow, and this is expected to double by 2040.

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Competitive Landscape

The global Ubiquitin Proteasome market is competitive and consists of a few major players. Companies like BioVision Inc., Promega Corporation, Merck KGaA, Takeda Pharmaceutical, Tocris Bioscience, among others, hold a substantial market share in the market.

Table of Contents


    1. 1.1 Study Deliverables

    2. 1.2 Study Assumptions

    3. 1.3 Scope of the Study




    1. 4.1 Market Overview

    2. 4.2 Market Drivers

      1. 4.2.1 Rising Prevalence of Cancer and Neurodegenerative Diseases

      2. 4.2.2 Increase in Research and Development Activities

    3. 4.3 Market Restraints

      1. 4.3.1 High Cost of the Drug and Stringent Regulations

      2. 4.3.2 Side Effects associated with Drugs

    4. 4.4 Porter's Five Force Analysis

      1. 4.4.1 Threat of New Entrants

      2. 4.4.2 Bargaining Power of Buyers/Consumers

      3. 4.4.3 Bargaining Power of Suppliers

      4. 4.4.4 Threat of Substitute Products

      5. 4.4.5 Intensity of Competitive Rivalry


    1. 5.1 By Application

      1. 5.1.1 Scientific Research

      2. 5.1.2 Treatment

        1. Cancer

        2. Neurodegenerative Disease

        3. Others

    2. 5.2 Geography

      1. 5.2.1 North America

        1. United States

        2. Canada

        3. Mexico

      2. 5.2.2 Europe

        1. Germany

        2. United Kingdom

        3. France

        4. Italy

        5. Spain

        6. Rest of Europe

      3. 5.2.3 Asia-Pacific

        1. China

        2. Japan

        3. India

        4. Australia

        5. South Korea

        6. Rest of Asia-Pacific

      4. 5.2.4 Middle-East and Africa

        1. GCC

        2. South Africa

        3. Rest of Middle-East and Africa

      5. 5.2.5 South America

        1. Brazil

        2. Argentina

        3. Rest of South America


    1. 6.1 Company Profiles

      1. 6.1.1 BioVision Inc.

      2. 6.1.2 Promega Corporation

      3. 6.1.3 Merck KGaA

      4. 6.1.4 Takeda Pharmaceutical

      5. 6.1.5 Tocris Bioscience

    2. *List Not Exhaustive

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

The Ubiquitin Proteasome Market market is studied from 2018 - 2026.

The Ubiquitin Proteasome Market is growing at a CAGR of 3.9% over the next 5 years.

Asia Pacific is growing at the highest CAGR over 2021- 2026.

North America holds highest share in 2020.

Merck KGaA , Takeda Pharmaceutical , BioVision Inc., Promega Corporation , Tocris Bioscience are the major companies operating in Ubiquitin Proteasome Market.

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