3D Bioprinting Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 1.44 Billion |
| Market Size (2029) | USD 3.00 Billion |
| CAGR (2024 - 2029) | 15.89 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
3D Bioprinting Market Analysis
The 3D Bioprinting Market size is estimated at USD 1.44 billion in 2024, and is expected to reach USD 3 billion by 2029, growing at a CAGR of 15.89% during the forecast period (2024-2029).
The 3D bioprinting market is growing due to the increasing technological advancements in the healthcare and pharmaceutical industries. Several government regulations to improve healthcare and increasing investments in R&D are also significant factors driving the market.
- 3D bioprinting is an emerging field represented by various biologically applied deposition and assembling systems, which include direct writing, photolithography, microstamping, extrusion, laser writing, stereolithography, electro-printing, microfluidics, and inkjet deposition. Healthcare is one of the major markets where 3D bioprinting has been bringing seismic change. This trend is major because of the increasing investments in healthcare applications, such as model and organ prototyping and production worldwide, and growing innovations in healthcare through 3D printing.
- The primary bioprinting applications include 3D bioprinted tissue and hair follicles, as they are very beneficial to cosmetics companies, especially in Europe, where animal testing for cosmetics was banned in 2013. A cosmetic company can test a product economically and ethically (i.e., not on animals) across varying skin types for more accurate results.
- Various companies are undergoing extensive R&D expenditures to boost technology through significant product developments and innovations. For instance, Organovo, a medical laboratory and research company, has been at the front of the R&D of 3D bioprinting in the United States.
- The company created its name by offering pharmaceutical companies its exVive3D Liver Tissue for medicine toxicity testing. It joined a few significant companies, including Merck and L'Oréal, in the healthcare space and is preparing to introduce its exVive3D Kidney Tissue product.
- Additionally, 3D bioprinting methods offer unique opportunities for positioning, stem cell distribution, and differentiation at the microscale to make the differentiated architecture of tissues while maintaining control and precision over the cellular microenvironment. Bioprinting also helps introduce a wide array of approaches to modify stem cell fate.
- The COVID-19 pandemic significantly accelerated technological advancements in pharmaceutical, medical devices, and manufacturing technologies due to disrupted supply chains and newer demands for treatments and materials. 3D bioprinting was one of these advancements, which primarily involves arranging encapsulated cells or other biological materials (bio-inks) using a 3D printer to construct tissue, organs, or biocompatible scaffolds that can promote tissue growth.
3D Bioprinting Market Trends
This section covers the major market trends shaping the 3D Bioprinting Market according to our research experts:
Drug Testing and Development to Hold Significant Market Share
- 3D bioprinters are highly important for drug testing and clinical trial applications. They are expected to drastically reduce the need for animal trials, thus being ethically beneficial and cost-effective. Traditionally, clinical trials for new drug development involved testing on animals with artificially-induced affected tissues.
- Traditionally, clinical trials for new drug development involved testing on animals with artificially-induced affected tissues. With the advent of 3D bioprinting, drug developers can address the complications associated with human clinical trials of new drugs by identifying them in a short period (since these can be tested with human-like 3D-printed tissues), thus reducing the losses incurred during late-stage failures.
- Lack of safety and efficacy are the principal causes of the failure of the drugs, which become evident only in Phases II and III of clinical trials.
- The bioprinted organs can identify the side effects of drugs and help medicine developers to streamline safe drug dosages to be administered to humans, as this technology allows for short drug discovery time. According to Pharma Intelligence, at the beginning of 2022, there were 11,351 drugs in the pre-clinical phase of the R&D. The market is expected to witness considerable opportunity over the forecast period.
- The regulatory agency of the US Food and Drug Administration is considering integrating alternatives for drug safety and efficacy assessment, providing scope for the market. Companies like Organovo (US-based) were instrumental in the development of a 3D bioprinter to develop liver and kidney tissue for drug discovery applications.
Asia-Pacific to Witness Significant Growth
- Asia-Pacific is the fastest-growing market for 3D bioprinting, mainly due to a strong existing consumer base that may drive the demand for 3D bioprinting, the massive scope of 3D printing in medical services, increasing R&D for 3D printing, and government support and tax incentives.
- The adoption of 3D printing in China is rapidly picking pace compared to other developed economies, such as North America and Europe, though it was not among the earliest adopters of the technology. The primary factor driving this growth is the support from the Chinese government in the innovation, development, and adoption of the technology across several end-user industries in the country. This trend has helped the research institutes ramp up their developments, significantly boosting the market's growth.
- The country also witnessed various kinds of research in bio-manufacturing. Tsinghua University (Beijing, China) is one of the leading laboratories in the interdisciplinary field of additive manufacturing and 3D bioprinting. Sponsored by the Ministry of Science and Technology of China, the National Natural Science Foundation of China, the National Health Commission of China, and the Beijing Municipal Science & Technology Commission, its bio-manufacturing center is highly dedicated to conducting research involving biomaterials, living cells, proteins, and other biological compounds, as basic building blocks to fabricate biomimetic structures. This research finds applications in various areas, such as tissue engineering, regenerative medicine, disease pathogenesis, drug screening, and tissue/organ-on-a-chip.
- Chinese researchers have rapidly advanced 3D bioprinting technology, such as the liquid-in-liquid printing method. This method involves liquid polymers that create a stable membrane where they meet. The resulting liquid structures, as they claim, can hold their shape for as long as 10 days before they begin to merge. Using this new technique, they could print an assortment of complex shapes. This further offers opportunities to print complex 3D-printed tissues made using living cells.
- According to the Indian Brand Equity Foundation, the healthcare sector is one of the fastest-growing industries in the country. It was estimated to grow threefold to INR 8.6 trillion (USD 133.44 billion) by 2022. In the recent budget, India's public expenditure on healthcare stood at 1.2% as a percentage of the GDP. The Government of India plans to increase public health spending to 2.5% of the GDP by 2025. Such trends in the healthcare sector are expected to boost the market's growth in the country significantly.
- Many Indian start-ups are making bioprinting technology popular through innovative solutions. For instance, Biop, established by BITS Pilani and Goa students, aims to change medical research by manufacturing the equipment and technology for 3D bioprinting. The product can form human tissues with one click, using sensors, actuators, and UV technology to control the 3D bioprinting. The company collaborated with MIT and Harvard for the same. The growth of start-ups, as well as the increasing elderly population and cancer cases, is among the significant factors set to fuel the market's growth over the forecast period.
- The Japanese government estimates that the regenerative medicine industry will record a revenue of JPY 1 trillion by 2030. The New Energy and Industrial Technology Development Organization (NEDO) expects that the emerging and innovative technologies, such as 3D bioprinting, may lead the market in the near future.
3D Bioprinting Industry Overview
The 3D bioprinting market is very competitive in nature. The market is concentrated due to the presence of various small and large players. Some of the significant players in the market are 3D Systems Corporation, Aspect Biosystems Ltd, GeSIM GmbH, Cellink AB, Cyfuse Biomedical KK, and Envision TEC GmbH.
- September 2022 - The Indian Institute of Science (IISc) announced its collaboration with CELLINK, a Sweden-based bioprinting solutions company, to provide two to three bioprinters to the Centre of Excellence (CoE), each of which uses a different printing technology at its own cost. India is expected to have its first dedicated center for 3D bioprinting technology in about two months at the Indian Institute of Science (IISc). IISc plans to set up its CoE in 3D bioprinting at its Centre for Biosystems Science and Engineering (BSSE). The CoE aims to advance the field by becoming a resource center for researchers, biopharma companies, hospitals, etc.
- June 2022 - REGEMAT 3D, a company at the forefront of personalized bio fabrication solutions, announced a partnership with Humabiologics, a company providing human-derived biomaterials for regenerative medicine, in response to the growing demand and to serve a broader life sciences customer base of the industry partners and academic institutions in the European bioprinting and drug testing market.
3D Bioprinting Market Leaders
Cellink
3D Systems Corporation
3D Bioprinting Solutions
REGEMAT 3D
Aspect Biosystems Ltd
*Disclaimer: Major Players sorted in no particular order
3D Bioprinting Market News
- SEP 2022 - 3D Systems announced a new 3D bioprinting subsidiary, Systemic Bio, to accelerate drug discovery and development. The new company will leverage 3D Systems' recent breakthroughs in the bioprinting of vascularized human organs and tissues to reduce cost, accelerate new drug development, and ultimately reduce or eliminate animal testing. Systemic Bio plans to open a new market for 3D Systems in the pharmaceutical sector, creating a biotech revenue stream that could approach USD 100 million annually over the next five years.
- MAY 2022 - Regemat 3D raised over EUR 500,000 to advance its 3D bioprinting technology. The firm's portfolio includes software, a bioreactor, materials and accessories, and its flagship BIO V1 and REG4LIFE 3D bioprinters. While the BIO V1 allows for a wide range of movements in the X, Y, and Z axis, providing it with the precision to place cells on varying surface types, the REG4LIFE facilitates independent Z-axis movement, enabling the use of two syringes on multi-well plates. According to the company, the machines are designed to meet disease modeling, drug testing, and organ-on-a-chip applications.
3D Bioprinting Market Report - Table of Contents
1. INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET INSIGHTS
4.1 Market Overview
4.2 Industry Attractiveness - Porter's Five Forces Analysis
4.2.1 Bargaining Power of Suppliers
4.2.2 Bargaining Power of Consumers
4.2.3 Threat of New Entrants
4.2.4 Threat of Substitutes
4.2.5 Intensity of Competitive Rivalry
4.3 Impact of COVID-19 on the 3D Bioprinting Market
5. MARKET DYNAMICS
5.1 Market Drivers
5.1.1 Increasing Geriatric Population
5.1.2 Increasing Investments in R&D
5.2 Market Challenges
5.2.1 Operational Challenges
6. MARKET SEGMENTATION
6.1 By Technology
6.1.1 Syringe/Extrusion Bioprinting
6.1.2 Inkjet Bioprinting
6.1.3 Magnetic Levitation Bioprinting
6.1.4 Laser-assisted Bioprinting
6.1.5 Other Technologies
6.2 By Component
6.2.1 3D Bioprinters
6.2.2 Biomaterials
6.2.3 Scaffolds
6.3 By Application
6.3.1 Drug Testing and Development
6.3.2 Regenerative Medicine
6.3.3 Food Testing
6.3.4 Research
6.3.5 Other Applications
6.4 By Geography
6.4.1 North America
6.4.1.1 United States
6.4.1.2 Canada
6.4.2 Europe
6.4.2.1 United Kingdom
6.4.2.2 Germany
6.4.2.3 France
6.4.2.4 Rest of Europe
6.4.3 Asia-Pacific
6.4.3.1 China
6.4.3.2 Japan
6.4.3.3 India
6.4.3.4 Rest of Asia-Pacific
6.4.4 Rest of the World
7. COMPETITIVE LANDSCAPE
7.1 Company Profiles
7.1.1 Cellink
7.1.2 3D Systems Corporation
7.1.3 3D Bioprinting Solutions
7.1.4 REGEMAT 3D
7.1.5 Aspect Biosystems Ltd
7.1.6 Cyfuse Biomedical KK
7.1.7 Envision TEC GmbH
7.1.8 Organovo Holdings Inc.
7.1.9 RegenHU SA
7.1.10 Stratasys Ltd
7.1.11 GeSIM GmbH
7.1.12 Arcam AB (GE Company)
- *List Not Exhaustive
8. INVESTMENT ANALYSIS
9. FUTURE OF THE MARKET
3D Bioprinting Industry Segmentation
The 3D bioprinting market is segmented by technology (syringe/extrusion bioprinting, inkjet bioprinting, magnetic levitation bioprinting, laser-assisted bioprinting), component (3D bioprinters, biomaterials, scaffolds), application (drug testing and development, regenerative medicine, food testing, research), and geography. 3D bioprinting, an extended application of AM (additive manufacturing), is now being explored for regenerative medicine and tissue engineering.
| By Technology | |
| Syringe/Extrusion Bioprinting | |
| Inkjet Bioprinting | |
| Magnetic Levitation Bioprinting | |
| Laser-assisted Bioprinting | |
| Other Technologies |
| By Component | |
| 3D Bioprinters | |
| Biomaterials | |
| Scaffolds |
| By Application | |
| Drug Testing and Development | |
| Regenerative Medicine | |
| Food Testing | |
| Research | |
| Other Applications |
| By Geography | ||||||
| ||||||
| ||||||
| ||||||
| Rest of the World |
3D Bioprinting Market Research FAQs
How big is the 3D Bioprinting Market?
The 3D Bioprinting Market size is expected to reach USD 1.44 billion in 2024 and grow at a CAGR of 15.89% to reach USD 3.00 billion by 2029.
What is the current 3D Bioprinting Market size?
In 2024, the 3D Bioprinting Market size is expected to reach USD 1.44 billion.
Who are the key players in 3D Bioprinting Market?
Cellink, 3D Systems Corporation, 3D Bioprinting Solutions, REGEMAT 3D and Aspect Biosystems Ltd are the major companies operating in the 3D Bioprinting Market.
Which is the fastest growing region in 3D Bioprinting Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in 3D Bioprinting Market?
In 2024, the North America accounts for the largest market share in 3D Bioprinting Market.
What years does this 3D Bioprinting Market cover, and what was the market size in 2023?
In 2023, the 3D Bioprinting Market size was estimated at USD 1.24 billion. The report covers the 3D Bioprinting Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the 3D Bioprinting Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
3D Bioprinting Industry Report
Statistics for the 2024 3D Bioprinting market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. 3D Bioprinting analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
