| Study Period | 2019 - 2030 |
| Base Year For Estimation | 2024 |
| Forecast Data Period | 2025 - 2030 |
| Historical Data Period | 2019 - 2023 |
| Market Size (2025) | USD 785.62 Million |
| Market Size (2030) | USD 937.59 Million |
| CAGR (2025 - 2030) | 3.60% |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market Analysis by Mordor Intelligence
The Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size is estimated at USD 785.62 million in 2025, and is expected to reach USD 937.59 million by 2030, at a CAGR of 3.6% during the forecast period (2025-2030).
The COVID-19 pandemic positively impacted the Middle East and Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market. Diabetes and uncontrolled hyperglycemia are risk factors for poor outcomes in patients with COVID-19 including an increased risk of severe illness or death. People with diabetes have a weaker immune system, the COVID-19 complication aggravates the condition, and the immune system gets weaker very fast. People with diabetes have more chances to get into serious complications rather than normal people.
Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and are used in the treatment of type 2 diabetes. DPP4 inhibitors increase insulin and GLP-1 secretion and are commonly prescribed for people suffering from type 2 diabetes. The use of DPP4 inhibitors in patients with COVID-19 with or even without type 2 diabetes offers a simple way to reduce the virus entry and replication into the airways and to hamper the sustained cytokine storm and inflammation within the lung in patients diagnosed with COVID-19 infection.
The diabetic prevalence is high in countries in the Middle East and African region. The gradually growing obesity rate, combined with the genetic predisposition for Type-2 diabetes, acted as a prominent driver for the increase in the Type-2 diabetic population over the last 40 years. Currently, nearly 10% of the population is living with diabetes. Diabetic patients in the Middle East and African region mainly suffer from Type-2 diabetes, accounting for nearly 90% of the total diabetic population in 2021.
Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period.
Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market Trends and Insights
The Tradjenta segment is expected to witness the highest CAGR in the Middle East and Africa Dipeptide Peptidase 4 (DDP-4) Inhibitors Market over the forecast period
The Tradjenta segment is expected to register the highest CAGR of about 7.6% in the Middle East and Africa dipeptide peptidase 4 (DDP-4) inhibitors market over the forecast period.
Tradjenta is a prescription drug that helps improve blood glucose control in adults with type-2 diabetes and is considered an adjunct treatment to diet and exercise. It is also used as an add-on therapy to insulin. Tradjenta should not be used in patients with type-1 diabetes or for the treatment of diabetic ketoacidosis. The persistence of oral antidiabetic treatment for type-2 diabetes is characterized by drug class, patient characteristics, and severity of renal impairment. Unlike older classes of glucose-lowering drugs such as sulfonylureas and insulin, DPP-4 inhibitors have an inherently low risk of causing hypoglycemia due to their glucose-dependent insulinotropic mechanism of action mediated via the incretin hormone glucagon-like peptide-1.
About 73 million adults were living with diabetes in 2021 which is estimated to increase to 95 million by 2030 in the IDF MENA Region. Governments in the ME have identified the threat of diabetes and started to respond with various policies, initiatives, and programs. Six out of 15 countries in this region still do not have a national operational action policy for diabetes. Many countries still do not have a national strategy to reduce overweight, obesity, and physical inactivity, which are important risk factors for diabetes. Most counties have fully implemented national diabetes treatment guidelines. However, constant measures are being taken to minimize diabetic complications.
Owing to the rising rate of obesity, the growing genetic factors for type-2 diabetes, the increasing prevalence, and the aforementioned factors, the market is likely to grow.
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Saudi Arabia holds the highest market share in the Middle East and African Dipeptide Peptidase 4 (DPP-4) Inhibitors Market in the current year
Saudi Arabia holds the highest market share in the Middle East and Africa dipeptide peptidase 4 (DPP-4) inhibitors market in the current year and is expected to register a CAGR of around 3.1% over the forecast period.
More than one in ten people in Saudi Arabia were living with diabetes, and the prevalence of the disease was expected to almost double by 2045, according to the IDF 2021 report. The IDF report also mentioned that 4.27 million people in Saudi Arabia, which has a population of about 34.8 million, have diabetes, while 1.86 million people have the disease but are yet to be diagnosed.
The growing incidence, prevalence, and progressive nature of the disease have encouraged the development of new drugs to provide additional treatment options for diabetic patients. Non-insulin treatments, used as first-line therapies for patients suffering from type 2 diabetes, currently capture more than half the sales in the anti-diabetic market. Over the past decade, two important classes have entered this market: dipeptidyl peptidase-4 inhibitors (DPP-4) and sodium-glucose cotransporter-2 inhibitors (SGLT-2). Oral antidiabetic agents work in various ways to reduce blood sugar levels in people with type-2 diabetes; some stimulate insulin secretion by the pancreas, and others improve the responsiveness of cells to insulin or prevent glucose production by the liver. Others slow the absorption of glucose after meals.
The Saudi Government declared that the country has a growing demand for quality healthcare services, spurred by changes including an increasing and aging population and a growing prevalence of lifestyle diseases such as diabetes and obesity in July 2022. The government and private sector are both involved in working on healthcare entities, certifications, and regulations. The government is taking steps to have 100 percent of Saudi citizens covered by insurance and is working towards ensuring affordability, access, and quality digital healthcare and primary care with cost-effectiveness.
Owing to the aforementioned factors, the market is expected to grow during the forecast period.
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Competitive Landscape
The Middle East and Africa dipeptide peptidase 4 (DPP-4) inhibitors market is consolidated, with a few major manufacturers like Eli Lilly, AstraZeneca, Merck, Boehringer Ingelheim, Novartis, etc., while the remaining market comprises other local or region-specific manufacturers.
Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Industry Leaders
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Merck
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Novartis
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Boehringer Ingelheim
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AstraZeneca
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Eli Lilly and Company
- *Disclaimer: Major Players sorted in no particular order
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Recent Industry Developments
- February 2023: Glenmark Pharmaceuticals Inc. received a 2nd tentative approval by the United States Food & Drug Administration for Saxagliptin Tablets, 2.5 mg and 5 mg, the generic version of Onglyza Tablets, 2.5 mg and 5 mg, of AstraZeneca.
- February 2022: Eurofarma launched Suganon (evogliptin) in Latin America, an innovative therapy for type 2 diabetes patients. Suganon (evogliptin) is a new DPP-4 enzyme inhibitor, which featured the benefits of offering convenient dosing, as well as having a low potential for interaction with other medications, ensuring greater ease and safety for prescribers and type-2 diabetes patients.
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Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market Report Scope
Dipeptidyl peptidase 4 (DPP-4) inhibitors are a pharmacological class of drugs for treating Type 2 diabetes. They help to control glycemia by increasing the levels of active incretins. The Middle East and Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market is segmented into drugs (Januvia (Sitagliptin), Onglyza (Saxagliptin), Tradjenta (Linagliptin), Vipidia/Nesina (Alogliptin), Galvus (Vildagliptin), and Others) and Geography. The report offers the value (in USD) and volume (in Units) for the above segments. Further, the report will cover a segment-wise breakdown (Value and Volume) for all the countries covered under the Table of Contents.
Drug
| Januvia (Sitagliptin) |
| Onglyza (Saxagliptin) |
| Tradjenta (Linagliptin) |
| Vipidia/Nesina (Alogliptin) |
| Galvus (Vildagliptin) |
| Other Drugs |
Geography
| Saudi Arabia |
| Iran |
| Egypt |
| Oman |
| South Africa |
| Rest of Middle East and Africa |
| Drug | Januvia (Sitagliptin) |
| Onglyza (Saxagliptin) | |
| Tradjenta (Linagliptin) | |
| Vipidia/Nesina (Alogliptin) | |
| Galvus (Vildagliptin) | |
| Other Drugs | |
| Geography | Saudi Arabia |
| Iran | |
| Egypt | |
| Oman | |
| South Africa | |
| Rest of Middle East and Africa |
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Key Questions Answered in the Report
How big is the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market?
The Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size is expected to reach USD 785.62 million in 2025 and grow at a CAGR of 3.60% to reach USD 937.59 million by 2030.
What is the current Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size?
In 2025, the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size is expected to reach USD 785.62 million.
Who are the key players in Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market?
Merck, Novartis, Boehringer Ingelheim, AstraZeneca and Eli Lilly and Company are the major companies operating in the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market.
What years does this Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market cover, and what was the market size in 2024?
In 2024, the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size was estimated at USD 757.34 million. The report covers the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market historical market size for years: 2019, 2020, 2021, 2022, 2023 and 2024. The report also forecasts the Middle East And Africa Dipeptide Peptidase 4 Inhibitors Market size for years: 2025, 2026, 2027, 2028, 2029 and 2030.
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Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors Market Report
Statistics for the 2025 Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Middle East And Africa Dipeptide Peptidase 4 (DPP-4) Inhibitors analysis includes a market forecast outlook for 2025 to 2030 and historical overview. Get a sample of this industry analysis as a free report PDF download.
