High-Performance Liquid Chromatography (HPLC) Market Size

High-Performance Liquid Chromatography (HPLC) Market Analysis

The High-Performance Liquid Chromatography Market size is estimated at USD 5 billion in 2024, and is expected to reach USD 6.20 billion by 2029, growing at a CAGR of 4.45% during the forecast period (2024-2029).

The COVID-19 pandemic significantly impacted the high-performance liquid chromatography (HPLC) market. For instance, a study published in the Journal of Pharmaceutical and Biomedical Analysis in May 2022 studied the permeability quantitation of Molnupiravir in nanoformulations. The study established that the reversed-phase HPLC method is more applicable for the routine analysis of Molnupiravir compared to the Liquid Chromatography - Mass Spectrometry / Mass Spectrometry methods. Furthermore, according to an article published by WHO in November 2021, the established method HPLC was employed to quantify remdesivir in marketed pharmaceutical formulations. The rise in the applications of HPLC systems in the COVID-19 study propelled the growth of the studied market. However, as the COVID-19 cases started to decline, the market began to show normal pre-pandemic level growth and is likely to continue its significant growth rate during the forecast period.

Factors such as advancements in HPLC technologies and the surge in usage of HPLC in pharmaceutical and bio-pharmaceutical companies are expected to drive the market's growth over the forecast period. For instance, according to an article published in the Journal of Current Opinion in Chemical Engineering in June 2021, HPLC is highly versatile, used for fast analysis and high-yield separation at both preparative and process scales, and is the most common separation method in the production of pharmaceutical and biopharmaceutical products. The article indicated that the combination of computational and experimental work could help the adoption of more complex models, reduce the simulation time, and facilitate faster screening of multidimensional operation spaces for parameter estimation and optimization. The advances made in the HPLC sector will likely add to the market growth in the forecast period.

Several key market players have also been interested in developing and manufacturing innovative HPLC-based systems for various laboratory functions, including diagnostics. For instance, in June 2021, Trivitron Healthcare launched HPLC-based diagnostic solutions, the HbA1c analyzers for monitoring diabetes, thalassemia, and hemoglobin variants. The fully automated NANO H5 analyzer can process five samples at a time. The NANO H110 is a compact, automated HPLC analyzer with a dual test mode for HbA1c test and Hb Variant detection, with a high sample loading capacity of 110 samples at a time. Such innovations are expected to propel market growth in the study period.

However, the lack of skilled personnel and the high cost of the HPLC systems will likely hinder the market growth in the forecast period.