Macular Degeneration Treatment Market Size

Macular Degeneration Treatment Market Analysis

The Macular Degeneration Treatment Market size is estimated at USD 15.47 billion in 2024, and is expected to reach USD 23.29 billion by 2029, growing at a CAGR of 8.51% during the forecast period (2024-2029).

The COVID-19 pandemic had potential economic impact and implications for most sectors, including the pharmaceutical and biotech industries. For instance, according to a research study published in the SN Comprehensive Clinical Medicine Journal in October 2020, the number of clinic visits for intravitreal injections (IVI) in the treatment of macular degeneration during one month from March 15 to April 14 of 2020 was compared to a similar time period in each of the last four years. The study demonstrated a decrease in clinic visits for intravitreal injections (IVI) compared with the same 4-week interval in the four previous years, and a total of 636 eyes received injections during a 4-week period of the COVID-19 outbreak in the Retina Clinic, Israel, in 2020, as compared to 995 injections in 2019. However, the easing of norms and the start of vaccination programs led to a recovery in the macular degeneration market.

The major factors attributing to the growth of the macular degeneration treatment market are the increasing burden of retinal disorders, the upsurge in the geriatric population, and an increase in research and development investments.

The increasing burden of retinal disorders is driving the market's growth. For instance, according to a research article published in the British Journal of Ophthalmology in August 2020, in Europe, age-related macular degeneration (AMD) is the main cause of visual impairment and blindness. About 67 million people in Europe are affected by age-related macular degeneration (AMD), and due to population aging, this number is expected to increase by 15% until 2050. As per the statistics, the increasing number of individuals with retinal disorders is directly proportional to market growth. Thus, the increasing burden of such disorders is driving the demand for macular degeneration treatment, which is further contributing to market growth.

Moreover, increasing research and development (R&D) and increasing clinical trials are other major factors for market growth. For instance, in November 2022, 4D Molecular Therapeutics, Inc., a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines, announced interim clinical data from cohort 1 of the Phase I/II clinical trial of intravitreal 4D-150 for wet AMD. The data focused on safety, tolerability, aflibercept transgene expression, and anti-VEGF clinical activity of the 4D-150 genetic medicine in patients enrolled in Cohort 1. Moreover, in January 2021, Novartis AG started a phase III clinical trial to evaluate the efficacy and safety of brolucizumab in patients with neovascular age-related macular degeneration. Such developments are fueling the growth of the macular degeneration market.

However, the increasing use of off-label drugs and lack of awareness regarding the disease are the major restraints on the growth of the market.