Carglumic Acid Market Size

Carglumic Acid Market Analysis

The Carglumic Acid Market is projected to register a CAGR of 7.2% during the forecast period.

COVID-19 brought a high infection rate among the population across the globe.The medical emergency known as hyperammonemia results in cerebral edema and neurologic impairment. Due to hyperammonemia from a disseminated cryptococcal infection, respiratory distress syndrome in COVID-19 patients may be the cause of such an infection.A rare genetic condition characterized by a lack of N-acetylglutamate synthase (NAGS) can be treated with the orphan medication carglumic acid, which aids in converting ammonia into urea in patients. This condition is creating a demand for carglumic acid medications for patients suffering from COVID-19 infections. Due to a deficit in the hepatic enzyme NAGS, it was utilized as a supplementary therapy for the treatment of acute hyperammonemia and as a maintenance therapy for chronic hyperammonemia. Hence, the COVID-19 pandemic significantly impacted the market.

The main things that are driving the growth of the carglumic acid market are the rise in cancers caused by drinking, smoking, and being inactive, as well as the rise in metabolic disorders like hepatic encephalopathy, Reye's syndrome, and cirrhosis around the world.WHO's key facts, which were last updated in May 2022, say that drinking too much can cause more than 200 diseases and injuries.According to the same source as above, alcohol-related disabilities caused 5.1% of the world's disease and injury burden in 2022.The amount of ammonia in the blood rises as people drink more alcohol. Carglumic acid is used and prescribed to lower the amount of ammonia in the blood.This is expected to drive the market.

In the same way, more people smoking and the problems that come with smoking are likely to increase the use of carglumic acid and help the market grow.For instance, according to the Office on Smoking and Health and the Chronic Disease Center (NCCDPHP), whose data was updated in March 2022, nearly 13 of every 100 United States adults aged 18 years or older (12.5%) smoked cigarettes in 2020. This means an estimated 30.8 million adults in the United States currently smoke cigarettes. More than 16 million Americans live with a smoking-related disease. Therefore, the smoking-related disease burden is anticipated to create demand for arglumic acid products, further fueling the market's growth.

In addition, hepatic encephalopathy (HE) is a nervous system disorder that is caused by severe liver disease and is often treated with carglumic acid. The number of people with covert hepatic encephalopathy (CHE) goes up to 54% when minimal hepatic encephalopathy (MHE) is found, according to an article in the Clinical Gastroenterology and Hepatology journal from August 2022.This burden of HE is expected to drive market growth. Additionally, according to the National Institute of Neurological Disorders and Stroke (NINDS) data published in February 2022, an estimated two children per year in the United States develop Reye's syndrome. This is expected to accumulate ammonia in the blood and thereby increase growth. Also, carglumic acid has shown potential for anti-tumor activity in breast cancer, along with various applications in cosmetics and chemicals, which are expected to fuel the global carglumic acid market during the forecast period.

But the market isn't growing as fast as it could because there are more problems in the development stage, patented products are expensive, and carglumic acid medicines can have serious side effects.